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1

T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes

Kula, Tomasz, Dezfulian, Mohammad H., Wang, Charlotte I., Abdelfattah, Nouran S., Hartman, Zachary C., Wucherpfennig, Kai W., Lyerly, Herbert Kim, Elledge, Stephen J.

Journal:

Year:

2019

Language:

english

File:

PDF, 5.27 MB

english, 2019

2

Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1

Moza, Beenu, Varma, Ashok K, Buonpane, Rebecca A, Zhu, Penny, Herfst, Christine A, Nicholson, Melissa J, Wilbuer, Anne-Kathrin, Seth, Nilufer P, Wucherpfennig, Kai W, McCormick, John K

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 378 KB

english, 2007

3

Analysis of the Relationship between Viral Infection and Autoimmune Disease

Vily Panoutsakopoulou, Marie E. Sanchirico, Katharina M. Huster, Marianne Jansson, Francesca Granucci, David J. Shim, Kai W. Wucherpfennig, Harvey Cantor

Journal:

Year:

2001

Language:

english

File:

PDF, 316 KB

english, 2001

4

Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

Tay, Rong En, Olawoyin, Olamide, Cejas, Paloma, Xie, Yingtian, Meyer, Clifford A., Ito, Yoshinaga, Weng, Qing Yu, Fisher, David E., Long, Henry W., Brown, Myles, Kim, Hye-Jung, Wucherpfennig, Kai W.

Journal:

Journal of Experimental Medicine

Year:

2020

File:

PDF, 6.66 MB

2020

5

Binding of conserved islet peptides by human and murine MHC class II molecules associated with susceptibility to type I diabetes

Bei Yu, Laurent Gauthier, Dorothee H. F. Hausmann, Kai W. Wucherpfennig

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000

6

Common T-cell receptor Vβ usage in oligoclonal T lymphocytes derived from cerebrospinal fluid and blood of patients with multiple sclerosis

Soon Jin Lee, Kai W. Wucherpfennig, Staley A. Brod, Deborah Benjamin, Howard L. Weiner, Dr David A. Hafler

Journal:

Annals of Neurology

Year:

1991

Language:

english

File:

PDF, 814 KB

english, 1991

7

Reply

David A. Hafler, Kai W. Wucherpfennig, Staley A. Brod, Howard L. Weiner

Journal:

Annals of Neurology

Year:

1991

Language:

english

File:

PDF, 107 KB

english, 1991

8

Frontline: Self-peptides that bind with low affinity to the diabetes-associated I-Ag7 molecule readily induce T cell tolerance in non-obese diabetic mice

Walter G. Ferlin, Evelyne Mougneau, Stéphanie Hugues, Heiner Appel, Mei-Huei Jang, Julie Cazareth, Lucie Beaudoin, Corinne Schricke, Agnès Lehuen, Kai W. Wucherpfennig, Nicolas Glaichenhaus

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

9

T-cell recognition of myelin basic protein

Kai W Wucherpfennig, Howard L Weiner, David A Hafler

Journal:

Immunology Today

Year:

1991

Language:

english

File:

PDF, 894 KB

english, 1991

10

Insights into autoimmunity gained from structural analysis of MHC–peptide complexes

Kai W Wucherpfennig

Journal:

Current Opinion in Immunology

Year:

2001

Language:

english

File:

PDF, 481 KB

english, 2001

11

Activation of autoreactive T cells by peptides from human pathogens

Stefan Hausmann, Kai W Wucherpfennig

Journal:

Current Opinion in Immunology

Year:

1997

Language:

english

File:

PDF, 839 KB

english, 1997

12

Structural alterations in peptide–MHC recognition by self-reactive T cell receptors

Kai W Wucherpfennig, Melissa J Call, Lu Deng, Roy Mariuzza

Journal:

Current Opinion in Immunology

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

13

Measuring T cell immunity to influenza vaccination in children after haemopoietic stem cell transplantation

W. Nicholas Haining, John W. Evans, Nilufer P. Seth, G. Derek Callaway, Kai W. Wucherpfennig, Lee M. Nadler, Eva C. Guinan

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 375 KB

english, 2004

14

10.1038/88694

Lee, Kon Ho, Wucherpfennig, Kai W., Wiley, Don C.

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 902 KB

english, 2001

15

The structural basis for intramembrane assembly of an activating immunoreceptor complex

Call, Matthew E, Wucherpfennig, Kai W, Chou, James J

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

16

HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

Anders, Anne-Kathrin, Call, Melissa J, Schulze, Monika-Sarah E D, Fowler, Kevin D, Schubert, David A, Seth, Nilufer P, Sundberg, Eric J, Wucherpfennig, Kai W

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

17

10.1038/ni0901-767

Wucherpfennig, Kai W., Eisenbarth, George S.

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 44 KB

english, 2001

18

Positively selecting peptides: their job does not end in the thymus

Wucherpfennig, Kai W, Gagnon, Etienne

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 488 KB

english, 2009

19

Unconventional topology of self peptide–major histocompatibility complex binding by a human autoimmune T cell receptor

Hahn, Michael, Nicholson, Melissa J, Pyrdol, Jason, Wucherpfennig, Kai W

Journal:

Nature Immunology

Year:

2005

Language:

english

File:

PDF, 825 KB

english, 2005

20

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Lang, Heather L.E., Jacobsen, Helle, Ikemizu, Shinji, Andersson, Christina, Harlos, Karl, Madsen, Lars, Hjorth, Peter, Sondergaard, Leif, Svejgaard, Arne, Wucherpfennig, Kai

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 401 KB

english, 2002

21

Infectious triggers for inflammatory neurological diseases

Wucherpfennig, Kai W.

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 846 KB

english, 2002

22

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

Korn, Thomas, Reddy, Jayagopala, Gao, Wenda, Bettelli, Estelle, Awasthi, Amit, Petersen, Troels R, Bäckström, B Thomas, Sobel, Raymond A, Wucherpfennig, Kai W, Strom, Terry B

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 414 KB

english, 2007

23

Common themes in the assembly and architecture of activating immune receptors

Call, Matthew E., Wucherpfennig, Kai W.

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 1.00 MB

english, 2007

24

Stoichiometry of the T-cell receptor–CD3 complex and key intermediates assembled in the endoplasmic reticulum

Call, Matthew E, Pyrdol, Jason, Wucherpfennig, Kai W

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 384 KB

english, 2004

25

MHC-Linked Susceptibility to Type 1 Diabetes : A Structural Perspective

KAI W. WUCHERPFENNIG

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 200 KB

2003

26

Myelin-specific Regulatory T Cells Accumulate in the Central Nervous System, but Fail to Suppress Pathogenic Effector T Cells at the Peak of Autoimmune Inflammation

Thomas Korn, Mohamed Oukka, Jay, Reddy, Estelle Bettelli, Amit Awasthi, Raymond Sobel, Kai Wucherpfennig, Vijay Kuchroo

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

27

Efficient Activation of Self-reactive T Cells from MS Patients with Altered Synapse Formation

Susana Gordo, David Schubert, Santosh Vardhana, Nilufer Seth, Jason Pyrdol, Khadir Raddassi, David Hafler, Michael Dustin, Kai Wucherpfennig

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

28

Structural Characterization of an Unusual Binding Mode of a Myelin-specific T Cell Receptor

Dhruv Sethi, David Schubert, Kathrin Wilbuer, Kai Wucherpfennig

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

29

Altered Synapse Formation by Self-reactive T Cells from MS Patients

David Schubert, Susana Gordo, Santosh Vardhana, Jason Pyrdol, Nilufer Seth, Khadir Raddassi, David Hafler, Michael Dustin, Kai Wucherpfennig

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

30

Helicobacter Pylori Infection and Immunity: Edited by Yoshimasa Yamamoto, Herman Friedman, Paul S. Hoffman, Kluwer Academic/Plenum Publishers, New York, Price: $135.00

Kai Wucherpfennig

Journal:

Journal of Neuroimmunology

Year:

2002

Language:

english

File:

PDF, 45 KB

english, 2002

31

Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions

Kevin C O'Connor, Tanuja Chitnis, Diane E Griffin, Sucheep Piyasirisilp, Amit Bar-Or, Samia Khoury, Kai W Wucherpfennig, David A Hafler

Journal:

Journal of Neuroimmunology

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

32

Improved assessment of aggregate size in Taxus plant cell suspension cultures using laser diffraction

Thomas Wucherpfennig, Jana Schilling, Dominik Sieblitz, Matthias Pump, Kai Schütte, Christoph Wittmann, Rainer Krull

Journal:

Engineering in Life Sciences

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

33

Autoimmunity in the Central Nervous System: Mechanisms of Antigen Presentation and Recognition

Kai W. Wucherpfennig

Journal:

Clinical Immunology and Immunopathology

Year:

1994

File:

PDF, 1.04 MB

1994

34

Structural Basis of Molecular Mimicry

Kai W Wucherpfennig

Journal:

Journal of Autoimmunity

Year:

2001

Language:

english

File:

PDF, 2.18 MB

english, 2001

35

Microbial peptides and superantigens in the pathogenesis of autoimmune diseases of the central nervous system

Stefan Brocke, Stefan Hausmann, Lawrence W. Steinman, Kai W. Wucherpfennig

Journal:

Seminars in Immunology

Year:

1998

Language:

english

File:

PDF, 99 KB

english, 1998

36

The Structure of the ζζ Transmembrane Dimer Reveals Features Essential for Its Assembly with the T Cell Receptor

Matthew E. Call, Jason R. Schnell, Chenqi Xu, Regina A. Lutz, James J. Chou, Kai W. Wucherpfennig

Journal:

Year:

2006

Language:

english

File:

PDF, 960 KB

english, 2006

37

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

Chenqi Xu, Etienne Gagnon, Matthew E. Call, Jason R. Schnell, Charles D. Schwieters, Christopher V. Carman, James J. Chou, Kai W. Wucherpfennig

Journal:

Year:

2008

Language:

english

File:

PDF, 950 KB

english, 2008

38

Response Multilayered Control of T Cell Receptor Phosphorylation

Etienne Gagnon, Chenqi Xu, Wei Yang, H. Hamlet Chu, Matthew E. Call, James J. Chou, Kai W. Wucherpfennig

Journal:

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

39

The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway

Monika-Sarah ED Schulze, Kai W Wucherpfennig

Journal:

Current Opinion in Immunology

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

40

Editorial overview

Kai W Wucherpfennig, Randolph J Noelle

Journal:

Current Opinion in Immunology

Year:

2011

Language:

english

File:

PDF, 155 KB

english, 2011

41

Convergence on a Distinctive Assembly Mechanism by Unrelated Families of Activating Immune Receptors

Jianwen Feng, David Garrity, Matthew E. Call, Howell Moffett, Kai W. Wucherpfennig

Journal:

Year:

2005

Language:

english

File:

PDF, 643 KB

english, 2005

42

Unusual Features of Self-Peptide/MHC Binding by Autoimmune T Cell Receptors

Melissa J. Nicholson, Michael Hahn, Kai W. Wucherpfennig

Journal:

Year:

2005

Language:

english

File:

PDF, 505 KB

english, 2005

43

Regulation of Activated CD4+ T Cells by NK Cells via the Qa-1–NKG2A Inhibitory Pathway

Linrong Lu, Koichi Ikizawa, Dan Hu, Miriam B.F. Werneck, Kai W. Wucherpfennig, Harvey Cantor

Journal:

Year:

2007

Language:

english

File:

PDF, 534 KB

english, 2007

44

Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

Anneli Peters, Lisa A. Pitcher, Jenna M. Sullivan, Meike Mitsdoerffer, Sophie E. Acton, Bettina Franz, Kai Wucherpfennig, Shannon Turley, Michael C. Carroll, Raymond A. Sobel, Estelle Bettelli, Vijay

Journal:

Year:

2011

Language:

english

File:

PDF, 2.92 MB

english, 2011

45

T cell receptor crossreactivity as a general property of T cell recognition

Kai W Wucherpfennig

Journal:

Molecular Immunology

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

46

Molecular mechanisms for the assembly of the T cell receptor–CD3 complex

Matthew E. Call, Kai W. Wucherpfennig

Journal:

Molecular Immunology

Year:

2004

Language:

english

File:

PDF, 377 KB

english, 2004

47

The structure and function of antigen receptors

Kai W. Wucherpfennig

Journal:

Seminars in Immunology

Year:

2007

Language:

english

File:

PDF, 45 KB

english, 2007

48

Polyspecificity of T cell and B cell receptor recognition

Kai W. Wucherpfennig, Paul M. Allen, Franco Celada, Irun R. Cohen, Rob De Boer, K. Christopher Garcia, Byron Goldstein, Ralph Greenspan, David Hafler, Philip Hodgkin, Erik S. Huseby, David C. Krakauer

Journal:

Seminars in Immunology

Year:

2007

Language:

english

File:

PDF, 139 KB

english, 2007

49

T cell receptor recognition of self and foreign antigens in the induction of autoimmunity

Kai W. Wucherpfennig, Dhruv Sethi

Journal:

Seminars in Immunology

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

50

The Organizing Principle in the Formation of the T Cell Receptor-CD3 Complex

Matthew E. Call, Jason Pyrdol, Martin Wiedmann, Kai W. Wucherpfennig

Journal:

Year:

2002

Language:

english

File:

PDF, 745 KB

english, 2002