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51

Imatinib for newly diagnosed chronic-phase chronic myeloid leukemia: results of a prospective study in Japan

Tadashi Nagai, Jin Takeuchi, Nobuaki Dobashi, Yuzuru Kanakura, Shuichi Taniguchi, Koji Ezaki, Chiaki Nakaseko, Akira Hiraoka, Masaya Okada, Yasushi Miyazaki, Toshiko Motoji, Masaaki Higashihara, Norif

Journal:

International Journal of Hematology

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

52

Molecular analysis of a patient with type I Glanzmann thrombasthenia and clinical impact of the presence of anti-αIIbβ3 alloantibodies

Hirokazu Kashiwagi, Kazunobu Kiyomizu, Tsuyoshi Kamae, Tsuyoshi Nakazawa, Seiji Tadokoro, Shuji Takiguchi, Yuichiro Doki, Yuzuru Kanakura, Yoshiaki Tomiyama

Journal:

International Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

53

Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: the AEGIS Clinical Trial

Yuzuru Kanakura, Kazuma Ohyashiki, Tsutomu Shichishima, Shinichiro Okamoto, Kiyoshi Ando, Haruhiko Ninomiya, Tatsuya Kawaguchi, Shinji Nakao, Hideki Nakakuma, Jun-ichi Nishimura, Taroh Kinoshita, Cami

Journal:

International Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 307 KB

english, 2011

54

Myeloid neoplasm-related gene abnormalities differentially affect dendritic cell differentiation from murine hematopoietic stem/progenitor cells

Jiro Fujita, Masao Mizuki, Masayasu Otsuka, Sachiko Ezoe, Hirokazu Tanaka, Yusuke Satoh, Kentaro Fukushima, Masahiro Tokunaga, Itaru Matsumura, Yuzuru Kanakura

Journal:

Immunology Letters

Year:

2011

Language:

english

File:

PDF, 2.57 MB

english, 2011

55

Relation between iron content of serum ferritin and clinical status factors extracted by factor analysis in patients with hyperferritinemia

Hachiro Yamanishi, Shigeru Iyama, Yoshihisa Yamaguchi, Yuzuru Kanakura, Yoshinori Iwatani

Journal:

Clinical Biochemistry

Year:

2002

Language:

english

File:

PDF, 105 KB

english, 2002

56

Roles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies

Itaru Matsumura, Masao Mizuki, Yuzuru Kanakura

Journal:

Year:

2008

Language:

english

File:

PDF, 196 KB

english, 2008

57

Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria

Yoshiko Murakami, Norimitsu Inoue, Tsutomu Shichishima, Rieko Ohta, Hideyoshi Noji, Yusuke Maeda, Jun-ichi Nishimura, Yuzuru Kanakura, Taroh Kinoshita

Journal:

British Journal of Haematology

Year:

2012

Language:

english

File:

PDF, 223 KB

english, 2012

58

Diffuse large B-cell lymphoma showing an interfollicular pattern of proliferation: a study of the Osaka Lymphoma Study Group

A Yamauchi, J Ikeda, I Nakamichi, M Kohara, S Fukuhara, M Hino, Y Kanakura, H Ogawa, H Sugiyama, A Kanamaru, K Aozasa

Journal:

Year:

2008

Language:

english

File:

PDF, 666 KB

english, 2008

59

Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group

Naoki Wada, Mona A A Zaki, Masaharu Kohara, Hiroyasu Ogawa, Haruo Sugiyama, Shosaku Nomura, Itaru Matsumura, Masayuki Hino, Yuzuru Kanakura, Hiroshi Inagaki, Eiichi Morii, Katsuyuki Aozasa

Journal:

Year:

2012

Language:

english

File:

PDF, 595 KB

english, 2012

60

Transdifferentiation between Mast Cell Subpopulations : (mast cells/tissue microenvironment/mutant mice/proteoglycans)

YUKIHIKO KITAMURA, TORU NAKANO, YUZURU KANAKURA

Journal:

Development, Growth & Differentiation

Year:

1986

Language:

english

File:

PDF, 355 KB

english, 1986

61

Expression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineage

H. KASHIWAGI, M. SHIRAGA, H. KATO, S. HONDA, M. SAKO, Y. KURATA, Y. KANAKURA, Y. TOMIYAMA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 567 KB

english, 2005

62

Impaired platelet function in a patient with P2Y12 deficiency caused by a mutation in the translation initiation codon

M. SHIRAGA, S. MIYATA, H. KATO, H. KASHIWAGI, S. HONDA, Y. KURATA, Y. TOMIYAMA, Y. KANAKURA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 357 KB

english, 2005

63

Critical role of ADP interaction with P2Y12 receptor in the maintenance of αIIbβ3 activation: association with Rap1B activation

T. KAMAE, M. SHIRAGA, H. KASHIWAGI, H. KATO, S. TADOKORO, Y. KURATA, Y. TOMIYAMA, Y. KANAKURA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 388 KB

english, 2006

64

Presence of platelet-associated anti-glycoprotein (GP)VI autoantibodies and restoration of GPVI expression in patients with GPVI deficiency

M. AKIYAMA, H. KASHIWAGI, K. TODO, M. MOROI, M. C. BERNDT, H. KOJIMA, Y. KANAKURA, Y. TOMIYAMA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 526 KB

english, 2009

65

Bleeding tendency and impaired platelet function in a patient carrying a heterozygous mutation in the thromboxane A2 receptor

T. KAMAE, K. KIYOMIZU, T. NAKAZAWA, S. TADOKORO, H. KASHIWAGI, S. HONDA, Y. KANAKURA, Y. TOMIYAMA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 612 KB

english, 2011

66

Platelet-associated IgM elevated in patients with chronic hepatitis C contains no anti-platelet autoantibodies

S. Kosugi, Y. Imai, Y. Kurata, Y. Tomiyama, M. Shiraga, S. Honda, M. Nishikawa, T. Yonezawa, Y. Kanakura, Y. Matsuzawa

Journal:

Liver International

Year:

1997

Language:

english

File:

PDF, 678 KB

english, 1997

67

10.1038/1209

Nishida, Toshirou, Hirota, Seiichi, Taniguchi, Masahiko, Hashimoto, Koji, Isozaki, Koji, Nakamura, Harumi, Kanakura, Yuzuru, Tanaka, Tomoyuki, Takabayashi, Arimichi, Matsuda, Hikaru, Kitamura, Yukihik

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

68

Determination of the breakpoints of a chromosomal translocation found in a patient with paroxysmal nocturnal hemoglobinuria

Inoue, Norimitsu, Izui, Tomohisa, Kuwayama, Maki, Nishimura, Junichi, Kurokawa, Ken, Machii, Takashi, Kanakura, Yuzuru, Kinoshita, Taroh

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 29 KB

english, 2001

69

Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts

Koma, Yu-ichiro, Ito, Akihiko, Watabe, Kenji, Hirata, Tatsumi, Mizuki, Masao, Yokozaki, Hiroshi, Kitamura, Toshio, Kanakura, Yuzuru, Kitamura, Yukihiko

Journal:

Laboratory Investigation

Year:

2005

Language:

english

File:

PDF, 265 KB

english, 2005

70

Role of DNA methylation for expression of novel stem cell marker CDCP1 in hematopoietic cells

Kimura, H, Morii, E, Ikeda, J-i, Ezoe, S, Xu, J-X, Nakamichi, N, Tomita, Y, Shibayama, H, Kanakura, Y, Aozasa, K

Journal:

Year:

2006

Language:

english

File:

PDF, 195 KB

english, 2006

71

Roles of tyrosine residues 845, 892 and 922 in constitutive activation of murine FLT3 kinase domain mutant

Ishiko, Jun, Mizuki, Masao, Matsumura, Itaru, Shibayama, Hirohiko, Sugahara, Hiroyuki, Scholz, Glen, Serve, Hubert, Kanakura, Yuzuru

Journal:

Year:

2005

Language:

english

File:

PDF, 489 KB

english, 2005

72

Difference between genomic actions of estrogen versus raloxifene in human ovarian cancer cell lines

Kamegai, H, Seino-Noda, H, Ezoe, S, Matsumura, I, Kanakura, Y, Sasaki, H, Hayakawa, J, Terai, Y, Kanemura, M, Tanabe-Kimura, A

Journal:

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

73

Determination of leukocyte counts in cerebrospinal fluid with a disposable plastic hemocytometer

Hachiro Yamanishi, Nobuko Imai, Etsuji Suehisa, Yuzuru Kanakura, Yoshinori Iwatani

Journal:

Journal of Clinical Laboratory Analysis

Year:

2007

Language:

english

File:

PDF, 116 KB

english, 2007

74

Expression of CD27 on Peripheral CD4+T-Lymphocytes Correlates with the Development of Severe Acute Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation

Hitoshi Yoshida, Tetsuo Maeda, Jun Ishikawa, Shinya Inoue, Hitomi Matsunaga, Satoru Kosugi, Masamichi Shiraga, Kenji Oritani, Yuzuru Kanakura, Yoshiaki Tomiyama

Journal:

International Journal of Hematology

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

75

Differentiation and Transdifferentiation of Mast Cells; a Unique Member of the Hematopoietic Cell Family

Yukihiko Kitamura, Yuzuru Kanakura, Jun Fujita, Toru Nakano

Journal:

Year:

1987

Language:

english

File:

PDF, 821 KB

english, 1987

76

The biology of GM-CSF: Regulation of production and interaction with its receptor

James D. Griffin, Stephen A. Cannistra, George D. Demetri, Timothy J. Ernst, Yuzuru Kanakura, Richard Sullivan

Journal:

Year:

1990

Language:

english

File:

PDF, 908 KB

english, 1990

77

Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation: Report of a case

Shigeru Miyagawa, Goro Matsumiya, Toshihiro Funatsu, Masao Yoshitatsu, Naozumi Sekiya, Shinya Fukui, Takaya Hoashi, Masatsugu Hori, Hideki Yoshikawa, Yuzuru Kanakura, Jun Ishikawa, Katsuyuki Aozasa, N

Journal:

Year:

2009

Language:

english

File:

PDF, 203 KB

english, 2009

78

Acceleration of a murine T-cell leukemia associated with loss of interleukin-3 producing activity

Akira Kuriu, Jun Fujita, Yuzuru Kanakura, Takeshi Yonezawa, Kazuko Yoshida, Yukihiko Kitamura

Journal:

Leukemia Research

Year:

1989

Language:

english

File:

PDF, 456 KB

english, 1989

79

Differential effects of a novel IFN-ζ/limitin and IFN-α on signals for Daxx induction and Crk phosphorylation that couple with growth control of megakaryocytes

Naoko Ishida, Kenji Oritani, Masamichi Shiraga, Hitoshi Yoshida, Sin-ichiro Kawamoto, Hidetoshi Ujiie, Hiroaki Masaie, Michiko Ichii, Yoshiaki Tomiyama, Yuzuru Kanakura

Journal:

Experimental Hematology

Year:

2005

Language:

english

File:

PDF, 477 KB

english, 2005

80

Regulation of human B lymphopoiesis by the transforming growth factor-β superfamily in a newly established coculture system using human mesenchymal stem cells as a supportive microenvironment

Michiko Ichii, Kenji Oritani, Takafumi Yokota, Makoto Nishida, Isao Takahashi, Takahiro Shirogane, Sachiko Ezoe, Norimitsu Saitoh, Rie Tanigawa, Paul W. Kincade, Yuzuru Kanakura

Journal:

Experimental Hematology

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

81

Stromal cell-free conditions favorable for human B lymphopoiesis in culture

Michiko Ichii, Kenji Oritani, Takafumi Yokota, Daniel C. Schultz, Jennifer L. Holter, Yuzuru Kanakura, Paul W. Kincade

Journal:

Journal of Immunological Methods

Year:

2010

Language:

english

File:

PDF, 982 KB

english, 2010

82

Predictability of the response to tyrosine kinase inhibitors via in vitro analysis of Bcr-Abl phosphorylation

Masaru Shibata, Sachiko Ezoe, Kenji Oritani, Keiko Matsui, Masahiro Tokunaga, Natsuko Fujita, Yuri Saito, Takayuki Takahashi, Masayuki Hino, Itaru Matsumura, Yuzuru Kanakura

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 678 KB

english, 2011

83

Study on melatonin like substance in both human and rat placental tissue

K. Nakazawa, Y. Kanakura, K. Kometanil, S. Iwasaki, Y. Yoshimura

Journal:

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

84

Study on melatonin in human and rat placental tissue

Kazumi Nakazawa, Yoichi Kanakura, Kunio Kometani, Shinya Iwasaki, Yasunori Yosimura

Journal:

Year:

1999

Language:

english

File:

PDF, 276 KB

english, 1999

85

Increase in platelet–large cell ratio in chronic myeloid leukemia

Osamu Kabutomori, Yuzuru Kanakura, Yoshinori Iwatani

Journal:

Leukemia Research

Year:

2001

Language:

english

File:

PDF, 42 KB

english, 2001

86

Platelet glycoprotein IIb as a target antigen in two patients with chronic idiopathic thrombocytopenic purpura

Y. Tomiyama, Y. Kurata, H. Mizutani, Y. Kanakura, T. Tsubakio, T. Yonezawa, S. Tarui

Journal:

British Journal of Haematology

Year:

1987

Language:

english

File:

PDF, 469 KB

english, 1987

87

Plasma cell leukaemia of non-producer type with missing light chain gene rearrangement

Nobuhiko Tominaga, Shuichi Katagiri, Yasushi Hamaguchi, Tetsuo Nishiura, Yuzuru Kanakura, Yoshio Kanayama, Kazuhiro Nagao, Yoshiyuki Kakiuchi, Kazuhiro Nishida, Tatsuo Abe, Tasuku Honjo, Takeshi Yonez

Journal:

British Journal of Haematology

Year:

1988

Language:

english

File:

PDF, 564 KB

english, 1988

88

A lower starting dose of eltrombopag is efficacious in Japanese patients with previously treated chronic immune thrombocytopenia

Y. TOMIYAMA, Y. MIYAKAWA, S. OKAMOTO, S. KATSUTANI, A. KIMURA, Y. OKOSHI, H. NINOMIYA, H. KOSUGI, S. NOMURA, K. OZAKI, Y. IKEDA, T. HATTORI, K. KATSURA, Y. KANAKURA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

89

Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality

Masaaki Takatoku, Takashi Uchiyama, Shinichiro Okamoto, Yuzuru Kanakura, Kenichi Sawada, Masao Tomonaga, Shinji Nakao, Tatsutoshi Nakahata, Mine Harada, Takashi Murate, Keiya Ozawa, the Japanese Natio

Journal:

European Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 588 KB

english, 2007

90

Presence of B-cell clones in T-cell lymphoma

Mona A.A. Zaki, Naoki Wada, Masaharu Kohara, Junichiro Ikeda, Yumiko Hori, Shigeki Fujita, Hiroyasu Ogawa, Haruo Sugiyama, Masayuki Hino, Yuzuru Kanakura, Eiichi Morii, Katsuyuki Aozasa

Journal:

European Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 489 KB

english, 2011

91

Expression of vascular permeability factor (VPFNEGF) messenger RNA by plasma cells: Possible involvement in the development of edema in chronic inflammation

Akihiko Ito, Seiichi Hirota, Hitoshi Mizuno, Yoshiaki Kawasaki, Teiji Takemura, Tetsuo Nishiura, Yuzuru Kanakura, Yoshinari Katayama, Shintaro Nomura, Yukihiko Kitamura

Journal:

Pathology International

Year:

1995

Language:

english

File:

PDF, 1.61 MB

english, 1995

92

Detection of Small Populations of CD59-Deficient Erythrocytes in Patients with Aplastic Anemia or Myelodysplastic Syndrome and Normal Individuals

Mitsuhiro Yamaguchi, Takashi Machii, Yasuhiko Azenishi, Junichi Nishimura, Masaru Shibano, Yuzuru Kanakura, Teruo Kitani

Journal:

Blood Cells, Molecules, and Diseases

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

93

Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) nonmyeloablative stem cell transplantation

K. Ikegame, T. Fujioka, Y. Taniguchi, S. Yoshihara, M. Kawakami, H. Hasei, K. Kaida, T. Masuda, E.H. Kim, Y. Kanakura, H. Ogawa

Journal:

Biology of Blood and Marrow Transplantation

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

94

Serum levels of soluble interleukin-2 receptor is a powerful marker of acute graft-versus host disease after HLA-haploidentical bone marrow transplantation

K. Kaida, K. Ikegame, T. Fujioka, Y. Taniguchi, S. Yoshihara, M. Kawakami, H. Hasei, S. Nishida, T. Masuda, M. Murakami, E.H. Kim, A. Tsuboi, Y. Oji, Y. Oka, T. Shirakata, Y. Ogawa, H. Kanakura

Journal:

Biology of Blood and Marrow Transplantation

Year:

2006

Language:

english

File:

PDF, 67 KB

english, 2006

95

Spectroscopic diagnosis of anti-phospholipid antibodies by visible and near-infrared spectroscopy in SLE patients’ plasma samples

Junzo Nojima, Akikazu Sakudo, Yukiko Hakariya, Hirohiko Kuratsune, Yasuyoshi Watanabe, Yuzuru Kanakura, Kazuyoshi Ikuta

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 195 KB

english, 2007

96

Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients

Junzo Nojima, Yumiko Masuda, Yoshinori Iwatani, Etsuji Suehisa, Yoshiaki Futsukaichi, Hirohiko Kuratsune, Yasuyoshi Watanabe, Toru Takano, Yoh Hidaka, Yuzuru Kanakura

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

97

A cell-death-defying factor, anamorsin mediates cell growth through inactivation of PKC and p38MAPK

Yuri Saito, Hirohiko Shibayama, Hirokazu Tanaka, Akira Tanimura, Yuzuru Kanakura

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 493 KB

english, 2011

98

NAD-dependent histone deacetylase, SIRT1, plays essential roles in the maintenance of hematopoietic stem cells

Keiko Matsui, Sachiko Ezoe, Kenji Oritani, Masaru Shibata, Masahiro Tokunaga, Natsuko Fujita, Akira Tanimura, Takao Sudo, Hirokazu Tanaka, Michael W. McBurney, Itaru Matsumura, Yuzuru Kanakura

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

99

Expression of HMGA2 in blood cells from patients with paroxysmal nocturnal haemoglobinuria

Yoshiko Murakami, Rieko Ohta, Norimitsu Inoue, Junichi Nishimura, Yuzuru Kanakura, Taroh Kinoshita

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

100

Enzymatic assay for determination of bicarbonate ion in plasma using urea amidolyase

Shigeki Kimura, Hachiro Yamanishi, Shigeru Iyama, Yoshihisa Yamaguchi, Yuzuru Kanakura

Journal:

Clinica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003