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1

Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

Löffler, A, Gruen, M, Wuchter, C, Schriever, F, Kufer, P, Dreier, T, Hanakam, F, Baeuerle, P A, Bommert, K, Karawajew, L

Journal:

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

2

Lineage Classification of Childhood Acute Lymphoblastic Leukemia according to the EGIL Recommendations: Results of the ALL-BFM 2000 Trial

R. Ratei, R. Schabath, L. Karawajew, M. Zimmermann, A. Möricke, M. Schrappe, W. Ludwig

Year:

2013

File:

PDF, 286 KB

2013

3

1H-NMR structural analysis of ethidium bromide complexation with self-complementary deoxytetranucleotides 5′-d (ApCpGpT), 5′-d (ApGpCpT), and 5′-d (TpGpCpA) in aqueous solution

D. B. Davies, L. Karawajew, A. N. Veselkov

Journal:

Year:

1996

Language:

english

File:

PDF, 999 KB

english, 1996

4

Y-box factor YB-1 is associated with the centrosome during mitosis

Martin Janz, Karsten Jürchott, Leonid Karawajew, Hans-Dieter Royer

Journal:

Gene Function & Disease

Year:

2000

Language:

english

File:

PDF, 1.27 MB

english, 2000

5

Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemias

Richard Ratei, Leonid Karawajew, Francis Lacombe, Krystyna Jagoda, Giovanni Del Poeta, Jaco Kraan, Maria De Santiago, János Kappelmayer, Elisabeth Björklund, W.-D. Ludwig, Jan Gratama, Alberto Orfao

Journal:

Cytometry Part B: Clinical Cytometry

Year:

2006

Language:

english

File:

PDF, 574 KB

english, 2006

6

Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible

Michael Norbert Dworzak, Giuseppe Gaipa, Richard Ratei, Marinella Veltroni, Angela Schumich, Oscar Maglia, Leonid Karawajew, Allessandra Benetello, Ulrike Pötschger, Zvenyslava Husak, Helmut Gadner, A

Journal:

Cytometry Part B: Clinical Cytometry

Year:

2008

Language:

english

File:

PDF, 614 KB

english, 2008

7

Modulation of antigen expression in B-cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: Evidence for a drug-induced regulatory phenomenon. Results of the AIEOP-BFM-ALL-FLOW-MRD-Study Group

Michael N. Dworzak, Giuseppe Gaipa, Angela Schumich, Oscar Maglia, Richard Ratei, Marinella Veltroni, Zvenyslava Husak, Giuseppe Basso, Leonid Karawajew, Helmut Gadner, Andrea Biondi

Journal:

Cytometry Part B: Clinical Cytometry

Year:

2010

Language:

english

File:

PDF, 468 KB

english, 2010

8

Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease

Doris Steinemann, Gunnar Cario, Martin Stanulla, Leonid Karawajew, Marcel Tauscher, Anja Weigmann, Gudrun Göhring, Wolf-Dieter Ludwig, Jochen Harbott, Bernhard Radlwimmer, Claus Bartram, Peter Lichter

Journal:

Genes, Chromosomes and Cancer

Year:

2008

Language:

english

File:

PDF, 287 KB

english, 2008

9

Analysis of the energetic state of heart cells after adenovirus-mediated expression of hALC-1

Udo B. Zacharzowsky, Gerhard Wolff, Monika Kott, Hannelore Haase, Holger Bartsch, Andreas K. Nuessler, Leonidas G. Baltas, Leonid Karawajew, Ingo Morano

Journal:

Journal of Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 223 KB

english, 2002

10

371 — Polyelectrolyte properties of nucleoproteins

Michael Böttger, Leonid Karawajew, Siegfried Scherneck, Heinz Fenske, Ruth Lindigkeit

Journal:

Bioelectrochemistry and Bioenergetics

Year:

1981

Language:

english

File:

PDF, 765 KB

english, 1981

11

Polyelectrolyte properties of nucleoproteins

Michael Böttger, Leonid Karawajew, Siegfried Scherneck, Heinz Fenske, Ruth Lindigkeit

Journal:

Journal of Electroanalytical Chemistry and Interfacial Electrochemistry

Year:

1981

Language:

english

File:

PDF, 583 KB

english, 1981

12

Mutation analysis of CD95 (APO-1/Fas) in childhood B-lineage acute lymphoblastic leukaemia

Christian Beltinger, Thomas Böhler, Leonid Karawajew, Wolf-Dieter Ludwig, Martin Schrappe, Klaus-Michael Debatin

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 402 KB

english, 1998

13

Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict the response to induction chemotherapy and relapse rate in childhood acute lymphoblastic leukaemia

Christian Wuchter, Leonid Karawajew, Velia Ruppert, Martin Schrappe, Jochen Harbott, Richard Ratei, Bernd Dörken, Wolf-Dieter Ludwig

Journal:

British Journal of Haematology

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

14

Structure–activity relation for synthetic phenoxazone drugs : Evidence for a direct correlation between DNA binding and pro-apoptotic activity

Alexei N. Veselkov, Vladimir Ya. Maleev, Evgenie N. Glibin, Leonid Karawajew, David B. Davies

Journal:

Year:

2003

Language:

english

File:

PDF, 552 KB

english, 2003

15

Physicochemical properties of salt-soluble, unsheared chromatin

M. Böttger, H. Fenske, L. Karawajew, H. Hamann, K. Karawajew, R. Lindigkeit

Journal:

Molecular Biology Reports

Year:

1982

Language:

english

File:

PDF, 558 KB

english, 1982

16

Physicochemical properties of salt-soluble, unsheared chromatin

L. Karawajew, H. Fenske, M. Böttger, R. Lindigkeit

Journal:

Molecular Biology Reports

Year:

1981

Language:

english

File:

PDF, 292 KB

english, 1981

17

Physicochemical properties of salt-soluble, unsheared chromatin

M. Böttger, L. Karawajew, H. Fenske, K. Grade, R. Lindigkeit

Journal:

Molecular Biology Reports

Year:

1981

Language:

english

File:

PDF, 297 KB

english, 1981

18

Monoclonal antibodies against rat mast cells differentiate between subtypes

H. Repke, N. Rossow, S. Savoly, J. Odarjuk, L. Karawajew, J. Gomes

Journal:

Inflammation Research

Year:

1987

Language:

english

File:

PDF, 220 KB

english, 1987

19

Immunophenotype and clinical characteristics of CD45-negative and CD45-positive childhood acute lymphoblastic leukemia

R. Ratei, C. Sperling, L. Karawajew, G. Schott, M. Schrappe, J. Harbott, H. Riehm, W.-D. Ludwig

Journal:

Annals of Hematology

Year:

1998

Language:

english

File:

PDF, 324 KB

english, 1998

20

Differential expression of the carcinoembryonic antigen-related cell adhesion molecules panCD66, CD66a, CD66c and of sialyl-Lewis x (CD15s) on blast cells of acute leukemias

Richard Ratei, Leonid Karawajew, Richard Schabath, Angelika Ehrfeldt, Fritz Grunert, Wolf-Dieter Ludwig

Journal:

International Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 237 KB

english, 2008

21

Monitoring treatment response of childhood precursor B-cell acute lymphoblastic leukemia in the AIEOP-BFM-ALL 2000 protocol with multiparameter flow cytometry: predictive impact of early blast reduction on the remission status after induction

Ratei, R, Basso, G, Dworzak, M, Gaipa, G, Veltroni, M, Rhein, P, Biondi, A, Schrappe, M, Ludwig, W-D, Karawajew, L

Journal:

Year:

2008

Language:

english

File:

PDF, 158 KB

english, 2008

22

Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo

Tamm, Ingo, Schumacher, Axel, Karawajew, Leonid, Ruppert, Velia, Arnold, Wolfgang, Nüssler, Andreas K, Neuhaus, Peter, Dörken, Bernd, Wolff, Gerhard

Journal:

Cancer Gene Therapy

Year:

2002

Language:

english

File:

PDF, 661 KB

english, 2002

23

Coexpression of p21WAF1/CIP1 in adenovirus vector transfected human primary hepatocytes prevents apoptosis resulting in improved transgene expression

Wolff, G, Schumacher, A, Nuessler, A K, Ruppert, V, Karawajew, L, Wehnes, E, Neuhaus, P, Dörken, B

Journal:

Year:

2003

Language:

english

File:

PDF, 352 KB

english, 2003

24

Differential CD95 expression and function in T and B lineage acute lymphoblastic leukemia cells

Karawajew, L, Wuchter, C, Ruppert, V, Drexler, H, Gruss, H-J, Dörken, B, Ludwig, W-D

Journal:

Year:

1997

Language:

english

File:

PDF, 510 KB

english, 1997

25

Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics

Wuchter, C, Karawajew, L, Ruppert, V, Büchner, T, Schoch, C, Haferlach, T, Ratei, R, Dörken, B, Ludwig, W-D

Journal:

Year:

1999

Language:

english

File:

PDF, 184 KB

english, 1999

26

Detection of acute leukemia cells with mixed lineage leukemia (MLL) gene rearrangements by flow cytometry using monoclonal antibody 7.1

Wuchter, C, Harbott, J, Schoch, C, Schnittger, S, Borkhardt, A, Karawajew, L, Ratei, R, Ruppert, V, Haferlach, T, Creutzig, U

Journal:

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

27

Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation

Cai, Z, Lin, M, Wuchter, C, Ruppert, V, Dörken, B, Ludwig, W-D, Karawajew, L

Journal:

Year:

2001

Language:

english

File:

PDF, 366 KB

english, 2001

28

In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-κB activity

Wuchter, C, Krappmann, D, Cai, Z, Ruppert, V, Scheidereit, C, Dörken, B, Ludwig, W-D, Karawajew, L

Journal:

Year:

2001

Language:

english

File:

PDF, 317 KB

english, 2001

29

P18 CLINICAL CHARACTERISTICS, PROGNOSTIC FACTORS AND SURVIVAL OF 36 ADULT PATIENTS WITH ACUTE PROMYELOCYTIC LEUKAEMIA.

Karawajew, L, Rhein, P, Czerwony, G, Ludwig, W-D, Meyer, L H, Karawajew, L, Debatin, K-M, Stahnke, K, Debatin, K-M, Kofler, R

Journal:

Year:

2003

Language:

english

File:

PDF, 454 KB

english, 2003

30

Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia

Rhein, P, Scheid, S, Ratei, R, Hagemeier, C, Seeger, K, Kirschner-Schwabe, R, Moericke, A, Schrappe, M, Spang, R, Ludwig, W-D, Karawajew, L

Journal:

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

31

Discriminant function analysis as decision support system for the diagnosis of acute leukemia with a minimal four color screening panel and multiparameter flow cytometry immunophenotyping

Ratei, R, Karawajew, L, Lacombe, F, Jagoda, K, Poeta, G D, Kraan, J, De Santiago, M, Kappelmayer, J, Björklund, E, Ludwig, W-D

Journal:

Year:

2007

Language:

english

File:

PDF, 230 KB

english, 2007

32

Mutations and Deletions of the TP53 Gene Predict Nonresponse to Treatment and Poor Outcome in First Relapse of Childhood Acute Lymphoblastic Leukemia

Hof, J., Krentz, S., van Schewick, C., Korner, G., Shalapour, S., Rhein, P., Karawajew, L., Ludwig, W.-D., Seeger, K., Henze, G.

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

33

Infection of cells with replication deficient adenovirus induces cell cycle alterations and leads to downregulation of E2F-1

Hartmut Kuhn, Uta Liebers, Christian Gessner, Leonid Karawajew, Velia Ruppert, Axel Schumacher, Christian Witt, Gerhard Wolff

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2002

Language:

english

File:

PDF, 311 KB

english, 2002

34

Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring

Joern Toedling, Peter Rhein, Richard Ratei, Leonid Karawajew, Rainer Spang

Journal:

BMC Bioinformatics

Year:

2006

Language:

english

File:

PDF, 4.78 MB

english, 2006

35

Bispecific IgA/IgM antibodies and their use in enzyme immunoassay

O. Behrsing, G. Kaiser, L. Karawajew, B. Micheel

Journal:

Journal of Immunological Methods

Year:

1992

Language:

english

File:

PDF, 741 KB

english, 1992

36

Production and ELISA application of bispecific monoclonal antibodies against fluorescein isothiocyanate (FITC) and horseradish peroxidase (HRP)

L. Karawajew, O. Behrsing, G. Kaiser, B. Micheel

Journal:

Journal of Immunological Methods

Year:

1988

Language:

english

File:

PDF, 409 KB

english, 1988

37

Bispecific antibody-producing hybrid hybridomas selected by a fluorescence activated cell sorter

L. Karawajew, B. Micheel, O. Behrsing, M. Gaestel

Journal:

Journal of Immunological Methods

Year:

1987

Language:

english

File:

PDF, 441 KB

english, 1987

38

The production and radioimmunoassay application of monoclonal antibodies to fluorescein isothiocyanate (FITC)

B. Micheel, P. Janstcheff, V. Böttger, G. Scharte, G. Kaiser, P. Stolley, L. Karawajew

Journal:

Journal of Immunological Methods

Year:

1988

Language:

english

File:

PDF, 446 KB

english, 1988

39

Flow sorting of hybrid hybridomas using the DNA stain Hoechst 33342

L. Karawajew, S. Rudchenko, T. Wlasik, I. Trakht, V. Rakitskaya

Journal:

Journal of Immunological Methods

Year:

1990

Language:

english

File:

PDF, 412 KB

english, 1990

40

Hybrid hybridomas producing bispecific antibodies to CEA and peroxidase isolated by a combination of HAT medium selection and fluorescence activated cell sorting

P. Jantscheff, L. Winkler, L. Karawajew, G. Kaiser, V. Böttger, B. Micheel

Journal:

Journal of Immunological Methods

Year:

1993

Language:

english

File:

PDF, 496 KB

english, 1993

41

A flow cytometric long-term cytotoxicity assay

Leonid Karawajew, Gundram Jung, Hans Wolf, Burkhard Micheel, Karin Ganzel

Journal:

Journal of Immunological Methods

Year:

1994

Language:

english

File:

PDF, 872 KB

english, 1994

42

A simple and sensitive method to study effects mediated by soluble lymphokines as demonstrated by the interaction of CD4+ and CD8+ cell subsets during T cell activation

Leonid Karawajew, Burkhard Micheel, Gundram Jung, Hans Wolf, Olaf Behrsing

Journal:

Journal of Immunological Methods

Year:

1994

Language:

english

File:

PDF, 340 KB

english, 1994

43

Flow diagnostics essential code: A simple and brief format for the summary of leukemia phenotyping

Hrušák, Ondřej, Basso, Giuseppe, Ratei, Richard, Gaipa, Giuseppe, Luria, Drorit, Mejstříková, Ester, Karawajew, Leonid, Buldini, Barbara, Rozenthal, Eti, Bourquin, Jean Pierre, Kalina, Tomáš, Sartor,

Journal:

Cytometry Part B: Clinical Cytometry

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

44

1 H NMR investigation of the hetero-association of phenanthridine dyes with Daunomycin: effect of substitution of amino with azido groups in the dye chromophore

Veselkov, Dennis A., Karawajew, Leonid, Veselkov, Alexei N., Davies *, David B.

Journal:

Molecular Physics

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

45

Vergleichsmessung der spezifischen Aktivität einer 90 Sr/ 90 Y-Lösung zwischen dem ASMW Berlin und dem WNIIM Leningrad

Brust, R., Schönfeld, E., Greupner, H., Kotschin, A. E., Karawajew, F. M.

Journal:

Isotopenpraxis Isotopes in Environmental and Health Studies

Year:

1974

File:

PDF, 369 KB

1974

46

Zur Methodik der Messung der Aktivität von umschlossenen γ-Strahlungsquellen mittels Ionisationskammern

Karawajew, F. M., Dričko, A. F., Greupner, H., Sucker, K.-H.

Journal:

Isotopenpraxis Isotopes in Environmental and Health Studies

Year:

1975

File:

PDF, 405 KB

1975

47

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia

Zaliova, M, Zimmermannova, O, Dörge, P, Eckert, C, Möricke, A, Zimmermann, M, Stuchly, J, Teigler-Schlegel, A, Meissner, B, Koehler, R, Bartram, C R, Karawajew, L, Rhein, P, Zuna, J, Schrappe, M, Cari

Journal:

Year:

2014

Language:

english

File:

PDF, 423 KB

english, 2014

48

High Interleukin-15 Expression Characterizes Childhood Acute Lymphoblastic Leukemia With Involvement of the CNS

Cario, G., Izraeli, S., Teichert, A., Rhein, P., Skokowa, J., Moricke, A., Zimmermann, M., Schrauder, A., Karawajew, L., Ludwig, W.-D., Welte, K., Schunemann, H. J., Schlegelberger, B., Schrappe, M.,

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 238 KB

english, 2007

49

Expression of Late Cell Cycle Genes and an Increased Proliferative Capacity Characterize Very Early Relapse of Childhood Acute Lymphoblastic Leukemia

Kirschner-Schwabe, R., Lottaz, C., Todling, J., Rhein, P., Karawajew, L., Eckert, C., von Stackelberg, A., Ungethum, U., Kostka, D., Kulozik, A. E., Ludwig, W.-D., Henze, G., Spang, R., Hagemeier, C.,

Journal:

Clinical Cancer Research

Year:

2006

Language:

english

File:

PDF, 611 KB

english, 2006

50

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia

Zaliova, M, Zimmermannova, O, Dörge, P, Eckert, C, Möricke, A, Zimmermann, M, Stuchly, J, Teigler-Schlegel, A, Meissner, B, Koehler, R, Bartram, C R, Karawajew, L, Rhein, P, Zuna, J, Schrappe, M, Cari

Journal:

Year:

2015

File:

PDF, 57 KB

2015