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1

Essential elements in depression and anxiety. Part I

Młyniec, Katarzyna, Davies, Claire Linzi, de Agüero Sánchez, Irene Gómez, Pytka, Karolina, Budziszewska, Bogusława, Nowak, Gabriel

Journal:

Pharmacological Reports

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

2

Essential elements in depression and anxiety. Part II

Młyniec, Katarzyna, Gaweł, Magdalena, Doboszewska, Urszula, Starowicz, Gabriela, Pytka, Karolina, Davies, Claire Linzi, Budziszewska, Bogusława

Journal:

Pharmacological Reports

Year:

2015

Language:

english

File:

PDF, 572 KB

english, 2015

3

The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect

Pytka, Karolina, Podkowa, Karolina, Rapacz, Anna, Podkowa, Adrian, Żmudzka, Elżbieta, Olczyk, Adrian, Sapa, Jacek, Filipek, Barbara

Journal:

Pharmacological Reports

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

4

Single Administration of HBK-15—a Triple 5-HT1A, 5-HT7, and 5-HT3 Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosterone

Pytka, Karolina, Głuch-Lutwin, Monika, Kotańska, Magdalena, Waszkielewicz, Anna, Kij, Agnieszka, Walczak, Maria

Journal:

Molecular Neurobiology

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

5

Serotonin receptors in depression and anxiety: Insights from animal studies

Żmudzka, Elżbieta, Sałaciak, Kinga, Sapa, Jacek, Pytka, Karolina

Journal:

Year:

2018

File:

PDF, 1.87 MB

2018

6

Novel aryloxyethyl derivatives of 1-(1-benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) phosphorylation-preferring serotonin 5 HT1A receptor biased agonists with robust antidepressant-like activity

Sniecikowska, Joanna, Głuch-Lutwin, Monika, Bucki, Adam, Więckowska, Anna, Siwek, Agata, Jastrzębska-Więsek, Magdalena, Partyka, Anna, Wilczyńska, Daria, Pytka, Karolina, Pociecha, Krzysztof, Cios, Ag

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 2.11 MB

2019

7

Synthesis and preliminary evaluation of pharmacological properties of some piperazine derivatives of xanthone

Szkaradek, Natalia, Rapacz, Anna, Pytka, Karolina, Filipek, Barbara, Siwek, Agata, Cegła, Marek, Marona, Henryk

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 611 KB

english, 2013

8

Reviews of Books

Librowski., Tadeusz, Pytka, Karolina, Szaleniec, Marcin

Journal:

Year:

1983

Language:

english

File:

PDF, 173 KB

english, 1983

9

Antihistaminic activity of carane derivatives in isolated guinea pig ileum

Librowski., Tadeusz, Pytka, Karolina, Szaleniec, Marcin

Journal:

Pharmacological Reports

Year:

2009

Language:

english

File:

PDF, 195 KB

english, 2009

10

SURGICAL LECTURES.

Librowski., Tadeusz, Pytka, Karolina, Szaleniec, Marcin

Journal:

Year:

1824

Language:

english

File:

PDF, 902 KB

english, 1824

11

Correction

Karolina, Pytka, Jacek, Sapa, Barbara, Filipek, Anna, Partyka, Magdalena, Jastrzębska-Więsek, Anna, Wesołowska

Journal:

Clinical Gastroenterology and Hepatology

Year:

2010

File:

PDF, 145 KB

2010

12

Potential antidepressant and anxiolytic properties of new phenylpiperazine derivaties

Karolina, Pytka, Jacek, Sapa, Barbara, Filipek, Anna, Partyka, Magdalena, Jastrzębska-Więsek, Anna, Wesołowska

Journal:

Pharmacological Reports

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

13

Does receptor activation initiate the NFκB pathway in hippocampal neurones?

Pytka, Karolina, Librowski, Tadeusz, Filipek, Barbara, Paul, Andrew, Bushell, Trevor

Journal:

Pharmacological Reports

Year:

2010

Language:

english

File:

PDF, 52 KB

english, 2010

14

Masthead

Pytka, Karolina, Librowski, Tadeusz, Filipek, Barbara, Paul, Andrew, Bushell, Trevor

Journal:

Journal of Vascular and Interventional Radiology

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

15

Antiarrhythmic, hypotensive and α1-adrenolytic properties of new 2-methoxyphenylpiperazine derivatives of xanthone

Rapacz, Anna, Pytka, Karolina, Sapa, Jacek, Kubacka, Monika, Filipek, Barbara, Szkaradek, Natalia, Marona, Henryk

Journal:

European Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

16

Alpha1-adrenoceptor antagonistic properties of novel phenylpiperazine xanthone derivatives

Rapacz, Anna, Sałat, Kinga, Pytka, Karolina, Nowiński, Leszek, Filipek, Barbara, Szkaradek, Natalia

Journal:

Pharmacological Reports

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

17

Obituary

Rapacz, Anna, Sałat, Kinga, Pytka, Karolina, Nowiński, Leszek, Filipek, Barbara, Szkaradek, Natalia

Journal:

Year:

1966

Language:

english

File:

PDF, 315 KB

english, 1966

18

Antidepressant-like properties of (R,S)-HBK-1 and its isomers, new xanthone derivatives, in mice

Pytka, Karolina, Sapa, Jacek, Rapacz, Anna, Filipek, Barbara, Partyka, Anna, Jastrzębska-Więsek, Magdalena, Wesołowska, Anna, Siwek, Agata, Szkaradek, Natalia, Marona, Henryk

Journal:

Pharmacological Reports

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

19

Antidepressant-like activity of a new piperazine derivative of xanthone in the forced swim test in mice: The involvement of serotonergic system

Pytka, Karolina, Rapacz, Anna, Zygmunt, Małgorzata, Olczyk, Adrian, Waszkielewicz, Anna, Sapa, Jacek, Filipek, Barbara

Journal:

Pharmacological Reports

Year:

2015

Language:

english

File:

PDF, 413 KB

english, 2015

20

Biofunctional studies of new 2-methoxyphenylpiperazine xanthone derivatives with α1-adrenolytic properties

Rapacz, Anna, Sapa, Jacek, Nowiński, Leszek, Mogilski, Szczepan, Pytka, Karolina, Filipek, Barbara, Siwek, Agata, Szkaradek, Natalia, Marona, Henryk

Journal:

Pharmacological Reports

Year:

2015

Language:

english

File:

PDF, 509 KB

english, 2015

21

Synthesis and Evaluation of Antidepressant-like Activity of Some 4-Substituted 1-(2-methoxyphenyl)Piperazine Derivatives

Waszkielewicz, Anna M., Pytka, Karolina, Rapacz, Anna, Wełna, Elżbieta, Jarzyna, Monika, Satała, Grzegorz, Bojarski, Andrzej, Sapa, Jacek, Żmudzki, Paweł, Filipek, Barbara, Marona, Henryk

Journal:

Chemical Biology & Drug Design

Year:

2015

Language:

english

File:

PDF, 660 KB

english, 2015

22

Antiarrhythmic activity of new 2-methoxyphenylpiperazine xanthone derivatives after ischemia/reperfusion in rats

Rapacz, Anna, Sapa, Jacek, Pytka, Karolina, Dudek, Magdalena, Filipek, Barbara, Szkaradek, Natalia, Marona, Henryk

Journal:

Pharmacological Reports

Year:

2015

Language:

english

File:

PDF, 297 KB

english, 2015

23

Cardiovascular activity of the chiral xanthone derivatives

Szkaradek, Natalia, Rapacz, Anna, Pytka, Karolina, Filipek, Barbara, Żelaszczyk, Dorota, Szafrański, Przemysław, Słoczyńska, Karolina, Marona, Henryk

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

24

The antidepressant-like activity of 6-methoxy-2-[4-(2-methoxyphenyl)piperazin-1-yl]-9H-xanthen-9-one involves serotonergic 5-HT1A and 5-HT2A/C receptors activation

Pytka, Karolina, Walczak, Maria, Kij, Agnieszka, Rapacz, Anna, Siwek, Agata, Kazek, Grzegorz, Olczyk, Adrian, Gałuszka, Adam, Waszkielewicz, Anna, Marona, Henryk, Sapa, Jacek, Filipek, Barbara

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 550 KB

english, 2015

25

The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect

Pytka, Karolina, Dziubina, Anna, Młyniec, Katarzyna, Dziedziczak, Agnieszka, Żmudzka, Elżbieta, Furgała, Anna, Olczyk, Adrian, Sapa, Jacek, Filipek, Barbara

Journal:

Pharmacological Reports

Year:

2015

Language:

english

File:

PDF, 491 KB

english, 2015

26

HBK-7 — A new xanthone derivative and a 5-HT1A receptor antagonist with antidepressant-like properties

Pytka, Karolina, Kazek, Grzegorz, Siwek, Agata, Mordyl, Barbara, Głuch-Lutwin, Monika, Rapacz, Anna, Olczyk, Adrian, Gałuszka, Adam, Waszkielewicz, Anna, Marona, Henryk, Sapa, Jacek, Filipek, Barbara,

Journal:

Pharmacology Biochemistry and Behavior

Year:

2016

Language:

english

File:

PDF, 464 KB

english, 2016

27

H3histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice

Dudek, Magdalena, Kuder, Kamil, Kołaczkowski, Marcin, Olczyk, Adrian, Żmudzka, Elżbieta, Rak, Aleksandra, Bednarski, Marek, Pytka, Karolina, Sapa, Jacek, Kieć-Kononowicz, Katarzyna

Journal:

Metabolic Brain Disease

Year:

2016

Language:

english

File:

PDF, 889 KB

english, 2016

28

Evaluation of antidepressant-like and anxiolytic-like activity of purinedione-derivatives with affinity for adenosine A2A receptors in mice

Dziubina, Anna, Szmyd, Karina, Zygmunt, Małgorzata, Sapa, Jacek, Dudek, Magdalena, Filipek, Barbara, Drabczyńska, Anna, Załuski, Michał, Pytka, Karolina, Kieć-Kononowicz, Katarzyna

Journal:

Pharmacological Reports

Year:

2016

Language:

english

File:

PDF, 569 KB

english, 2016

29

HBK-14 and HBK-15 with antidepressant-like and/or memory-enhancing properties increase serotonin levels in the hippocampus after chronic treatment in mice

Pytka, Karolina, Gawlik, Katarzyna, Pawlica-Gosiewska, Dorota, Witalis, Jadwiga, Waszkielewicz, Anna

Journal:

Metabolic Brain Disease

Year:

2017

Language:

english

File:

PDF, 831 KB

english, 2017

30

Design, synthesis and anticonvulsant-analgesic activity of new N-[(phenoxy)alkyl]- and N-[(phenoxy)ethoxyethyl]aminoalkanols

Rapacz, Anna, Waszkielewicz, Anna M., Pańczyk, Katarzyna, Pytka, Karolina, Koczurkiewicz, Paulina, Piska, Kamil, Pękala, Elżbieta, Budziszewska, Bogusława, Starek-Świechowicz, Beata, Marona, Henryk

Journal:

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

31

The role of melatonin, neurokinin, neurotrophic tyrosine kinase and glucocorticoid receptors in antidepressant-like effect

Pytka, Karolina, Młyniec, Katarzyna, Podkowa, Karolina, Podkowa, Adrian, Jakubczyk, Magdalena, Żmudzka, Elżbieta, Lustyk, Klaudia, Sapa, Jacek, Filipek, Barbara

Journal:

Pharmacological Reports

Year:

2017

Language:

english

File:

PDF, 472 KB

english, 2017

32

HBK-15 protects mice from stress-induced behavioral disturbances and changes in corticosterone, BDNF, and NGF levels

Pytka, Karolina, Głuch-Lutwin, Monika, Kotańska, Magdalena, Żmudzka, Elżbieta, Jakubczyk, Magdalena, Waszkielewicz, Anna, Janiszewska, Paulina, Walczak, Maria

Journal:

Behavioural Brain Research

Year:

2017

Language:

english

File:

PDF, 1.53 MB

english, 2017

33

Novel 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands With Antipsychotic-like, Mood-Modulating And Procognitive Activity

Bucki, Adam, Marcinkowska, Monika, Śniecikowska, Joanna, Więckowski, Krzysztof, Pawłowski, Maciej H., Głuch-Lutwin, Monika, Gryboś, Anna, Siwek, Agata, Pytka, Karolina, Jastrzębska-Więsek, Magdalena,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.01 MB

english, 2017

34

HBK-14 and HBK-15, triple 5-HT 1A , 5-HT 7 and 5-HT 3 antagonists with potent antidepressant- and anxiolytic-like properties, increase seizure threshold in various seizure tests in mice

Pytka, Karolina, Socała, Katarzyna, Rapacz, Anna, Nieoczym, Dorota, Pieróg, Mateusz, Gryboś, Anna, Siwek, Agata, Waszkielwicz, Anna, Wlaź, Piotr

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 575 KB

english, 2017

35

Synthesis and activity of di- or trisubstituted N -(phenoxyalkyl)- or N -{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system

Pańczyk, Katarzyna, Pytka, Karolina, Jakubczyk, Magdalena, Rapacz, Anna, Sałat, Kinga, Furgała, Anna, Siwek, Agata, Głuch-Lutwin, Monika, Gryboś, Anna, Słoczyńska, Karolina, Pękala, Elżbieta, Żmudzki,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 2.41 MB

english, 2018

36

A Comparison of the Anorectic Effect and Safety of the Alpha2-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity

Dudek, Magdalena, Knutelska, Joanna, Bednarski, Marek, Nowiński, Leszek, Zygmunt, Małgorzata, Mordyl, Barbara, Głuch-Lutwin, Monika, Kazek, Grzegorz, Sapa, Jacek, Pytka, Karolina, Aguila, Marcia B.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

37

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT1A and 5-HT7 Antagonists in Animal Models

Pytka, Karolina, Partyka, Anna, Jastrzębska-Więsek, Magdalena, Siwek, Agata, Głuch-Lutwin, Monika, Mordyl, Barbara, Kazek, Grzegorz, Rapacz, Anna, Olczyk, Adrian, Gałuszka, Adam, Błachuta, Marian, Was

Journal:

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

38

Metabolic and Cardiovascular Benefits and Risks of EMD386088—A 5-HT6 Receptor Partial Agonist and Dopamine Transporter Inhibitor

Kotańska, Magdalena, Śniecikowska, Joanna, Jastrzębska-Więsek, Magdalena, Kołaczkowski, Marcin, Pytka, Karolina

Journal:

Frontiers in Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.82 MB

english, 2017

39

Chemically Homogenous Compounds with Antagonistic Properties at All α1-Adrenoceptor Subtypes but not β1-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats

Pytka, Karolina, Lustyk, Klaudia, Żmudzka, Elżbieta, Kotańska, Magdalena, Siwek, Agata, Zygmunt, Małgorzata, Dziedziczak, Agnieszka, Śniecikowska, Joanna, Olczyk, Adrian, Gałuszka, Adam, Śmieja, Jaros

Journal:

Frontiers in Pharmacology

Year:

2016

Language:

english

File:

PDF, 3.59 MB

english, 2016

40

Serotonin receptors in depression and anxiety: Insights from animal studies

Żmudzka, Elżbieta, Sałaciak, Kinga, Sapa, Jacek, Pytka, Karolina

Journal:

Year:

2018

Language:

english

File:

PDF, 1.87 MB

english, 2018

41

HBK-17, a 5-HT1A Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling

Pytka, Karolina, Głuch-Lutwin, Monika, Żmudzka, Elżbieta, Sałaciak, Kinga, Siwek, Agata, Niemczyk, Katarzyna, Walczak, Maria, Smolik, Magdalena, Olczyk, Adrian, Gałuszka, Adam, Śmieja, Jarosław, Filip

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

42

Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Żelaszczyk, Dorota, Jakubczyk, Magdalena, Pytka, Karolina, Rapacz, Anna, Walczak, Maria, Janiszewska, Paulina, Pańczyk, Katarzyna, Żmudzki, Paweł, Słoczyńska, Karolina, Marona, Henryk, Waszkielewicz,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 1.18 MB

english, 2019

43

Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Żelaszczyk, Dorota, Jakubczyk, Magdalena, Pytka, Karolina, Rapacz, Anna, Walczak, Maria, Janiszewska, Paulina, Pańczyk, Katarzyna, Żmudzki, Paweł, Słoczyńska, Karolina, Marona, Henryk, Waszkielewicz,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

File:

PDF, 1.18 MB

2019

44

Mitogenâactivated protein kinase phosphataseâ2 deletion modifies ventral tegmental area function and connectivity and alters reward processing

Pytka, Karolina, Dawson, Neil, Tossell, Kyoko, Ungless, Mark A., Plevin, Robin, Brett, Ros R., Bushell, Trevor J.

Journal:

European Journal of Neuroscience

Year:

2020

File:

PDF, 1.03 MB

2020

45

Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD)

Bucki, Adam, Marcinkowska, Monika, Åniecikowska, Joanna, ZagÃ³rska, Agnieszka, Jamrozik, Marek, PawÅowski, Maciej, GÅuch-Lutwin, Monika, Siwek, Agata, Jakubczyk, Magdalena, Pytka, Karolina, JastrzÄ

Journal:

European Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.82 MB

2020

46

Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model

KotaÅska, Magdalena, Mika, Kamil, SaÅaciak, Kinga, Wheeler, Lee, Sapa, Jacek, KieÄ-Kononowicz, Katarzyna, Pytka, Karolina

Journal:

Pharmacology Biochemistry and Behavior

Year:

2020

File:

PDF, 834 KB

2020

47

Discovery of novel pERK1/2- or Î²-Arrestin-Preferring 5-HT1A Receptor Biased Agonists: Diversified Therapeutic-Like vs. Side Effects Profile

Sniecikowska, Joanna, GÅuch-Lutwin, Monika, Bucki, Adam, WiÄckowska, Anna, Siwek, Agata, Jastrz&#281, bska-Wi&#281, sek, Magdalena, Partyka, Anna, Wilczynska, Daria, Pytka, Karolina, Latacz, Gniewomir

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.82 MB

2020