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51

Nevirapine and Efavirenz Elicit Different Changes in Lipid Profiles in Antiretroviral- Therapy-Naive Patients Infected with HIV-1

van Leth, Frank, Phanuphak, Prahpan, Stroes, Erik, Gazzard, Brian, Cahn, Pedro, Raffi, François, Wood, Robin, Bloch, Mark, Katlama, Christine, Kastelein, John J. P., Schechter, Mauro, Murphy, Robert L

Journal:

Year:

2004

Language:

english

File:

PDF, 4.30 MB

english, 2004

52

Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome

Nicholls, Stephen J., Kastelein, John J. P., Schwartz, Gregory G., Bash, Dianna, Rosenson, Robert S., Cavender, Matthew A., Brennan, Danielle M., Koenig, Wolfgang, Jukema, J. Wouter, Nambi, Vijay, Wri

Journal:

JAMA The Journal of the American Medical Association

Year:

2014

Language:

english

File:

PDF, 469 KB

english, 2014

53

Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile

van der Valk, Marc, Kastelein, John J. P., Murphy, Robert L., van Leth, Frank, Katlama, Christine, Horban, Andrej, Glesby, Marshall, Behrens, Georg, Clotet, Bonaventura, Stellato, Rebecca K., Molhuize

Journal:

Year:

2001

Language:

english

File:

PDF, 167 KB

english, 2001

54

Evaluating Bococizumab, a Monoclonal Antibody to PCSK9, on Lipid Levels and Clinical Events in Broad Patient Groups With and Without Prior Cardiovascular Events: Rationale and Design of the SPIRE Lipid Lowering and SPIRE Cardiovascular Outcomes Trials

Ridker, Paul M., Amarenco, Pierre, Brunell, Robert, Glynn, Robert J., Jukema, J. Wouter, Kastelein, John J.P., Koenig, Wolfgang, Nissen, Steven, Revkin, James, Santos, Raul D., Schwartz, Pamela F., Yu

Journal:

American Heart Journal

Year:

2016

Language:

english

File:

PDF, 666 KB

english, 2016

55

PCSK9 inhibition: the way forward in the treatment of dyslipidemia

Stoekenbroek, Robert M., Kastelein, John JP, Huijgen, Roeland

Journal:

Year:

2015

Language:

english

File:

PDF, 2.24 MB

english, 2015

56

Immunologic and Therapeutic Synergy of IL-27 and IL-2: Complete Regression of Neuroblastoma Metastases in the Liver and Bone Marrow

Salcedo, Rosalba, Hixon, Julie, Stauffer, Jim, Khan, Tahira, Lincoln, Erin, Back, Timothy, Kastelein, Robert, Wigginton, Jon

Journal:

Journal of Immunotherapy

Year:

2005

Language:

english

File:

PDF, 1.45 MB

english, 2005

57

Interleukin-27 Enhances Tumor Cell MHC Class I Expression and Specific T Cell Reactivity and Mediates CD8+ T-Cell Dependent Regression of Primary and/or Metastatic Murine Neuroblastoma Tumors

Salcedo, Rosalba, Hahn, Cynthia, Stauffer, Jimmy, Lincoln, Erin, Hixon, Julie, Shafer-Weaver, Kimberly, Malyguine, Anatoly, Kastelein, Robert, Wigginton, Jon

Journal:

Journal of Immunotherapy

Year:

2004

Language:

english

File:

PDF, 47 KB

english, 2004

58

Review Canadian Journal of Cardiology – Advances in Atherosclerosis: Determinants and Prevention

Bruikman, Caroline S., Stoekenbroek, Robert M., Hovingh, G.Kees, Kastelein, John P.

Journal:

Canadian Journal of Cardiology

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

59

Safety of Very Low Low-Density Lipoprotein Cholesterol Levels With Alirocumab

Robinson, Jennifer G., Rosenson, Robert S., Farnier, Michel, Chaudhari, Umesh, Sasiela, William J., Merlet, Laurence, Miller, Kathryn, Kastelein, John J.P.

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

60

Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients

Ridker, Paul M, Revkin, James, Amarenco, Pierre, Brunell, Robert, Curto, Madelyn, Civeira, Fernando, Flather, Marcus, Glynn, Robert J., Gregoire, Jean, Jukema, J. Wouter, Karpov, Yuri, Kastelein, John

Journal:

New England Journal of Medicine

Year:

2017

Language:

english

File:

PDF, 213 KB

english, 2017

61

Lipid-Reduction Variability and Antidrug-Antibody Formation with Bococizumab

Ridker, Paul M, Tardif, Jean-Claude, Amarenco, Pierre, Duggan, William, Glynn, Robert J., Jukema, J. Wouter, Kastelein, John J.P., Kim, Albert M., Koenig, Wolfgang, Nissen, Steven, Revkin, James, Rose

Journal:

New England Journal of Medicine

Year:

2017

Language:

english

File:

PDF, 246 KB

english, 2017

62

Can we afford not to screen for FH?

Stoekenbroek, Robert M., Kastelein, John J.P., Hovingh, G. Kees

Journal:

European Heart Journal

Year:

2017

Language:

english

File:

PDF, 136 KB

english, 2017

63

Dyslipidaemia: Statin-associated muscle symptoms — really all in the mind?

Stoekenbroek, Robert M., Kastelein, John J. P.

Journal:

Nature Reviews Cardiology (formerly Nature Clinical Practice Cardiovascular Medicine)

Year:

2017

Language:

english

File:

PDF, 142 KB

english, 2017

64

Homozygous familial hypercholesterolaemia: light at the end of the tunnel

Stoekenbroek, Robert M., Kees Hovingh, G., Kastelein, John J.P.

Journal:

European Heart Journal

Year:

2017

Language:

english

File:

PDF, 107 KB

english, 2017

65

Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk

Ference, Brian A., Kastelein, John J. P., Ginsberg, Henry N., Chapman, M. John, Nicholls, Stephen J., Ray, Kausik K., Packard, Chris J., Laufs, Ulrich, Brook, Robert D., Oliver-Williams, Clare, Butter

Journal:

JAMA The Journal of the American Medical Association

Year:

2017

Language:

english

File:

PDF, 557 KB

english, 2017

66

Proprotein convertase subtilisin/kexin type 9

Stoekenbroek, Robert M., Kastelein, John J.P.

Journal:

Current Opinion in Cardiology

Year:

2018

Language:

english

File:

PDF, 244 KB

english, 2018

67

Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins: Pre-Specified Secondary End Points in ORION 1

Ray, Kausik K., Stoekenbroek, Robert M., Kallend, David, Leiter, Lawrence A., Landmesser, Ulf, Wright, R. Scott, Wijngaard, Peter, Kastelein, John J.

Journal:

Year:

2018

File:

PDF, 2.59 MB

2018

68

Inclisiran for the treatment of cardiovascular disease: the ORION clinical development program

Stoekenbroek, Robert M, Kallend, David, Wijngaard, Peter LJ, Kastelein, John JP

Journal:

Future Cardiology

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

69

Moving Targets

Larsen, Lars E., Stoekenbroek, Robert M., Kastelein, John J.P., Holleboom, Adriaan G.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2019

File:

PDF, 1.20 MB

2019

70

Effect of 1 or 2 Doses of Inclisiran on Low-Density Lipoprotein Cholesterol Levels

Ray, Kausik K., Stoekenbroek, Robert M., Kallend, David, Nishikido, Toshiyuki, Leiter, Lawrence A., Landmesser, Ulf, Wright, R. Scott, Wijngaard, Peter L. J., Kastelein, John J. P.

Journal:

JAMA Cardiology

Year:

2019

Language:

english

File:

PDF, 563 KB

english, 2019

71

Usefulness of Gemcabene in Homozygous Familial Hypercholesterolemia (from COBALT-1)

Gaudet, Daniel, Durst, Ronen, Lepor, Norman, Bakker-Arkema, Rebecca, Bisgaier, Charles, Masson, Liz, Golden, Lee, Kastelein, John J, Hegele, Robert A, Stein, Evan

Journal:

The American Journal of Cardiology

Year:

2019

Language:

english

File:

PDF, 634 KB

english, 2019

72

Effect of 1 or 2 Doses of Inclisiran on Low-Density Lipoprotein Cholesterol Levels

Ray, Kausik K., Stoekenbroek, Robert M., Kallend, David, Nishikido, Toshiyuki, Leiter, Lawrence A., Landmesser, Ulf, Wright, R. Scott, Wijngaard, Peter L. J., Kastelein, John J. P.

Journal:

JAMA Cardiology

Year:

2019

File:

PDF, 563 KB

2019

73

Usefulness of Gemcabene in Homozygous Familial Hypercholesterolemia (from COBALT-1)

Gaudet, Daniel, Durst, Ronen, Lepor, Norman, Bakker-Arkema, Rebecca, Bisgaier, Charles, Masson, Liz, Golden, Lee, Kastelein, John J, Hegele, Robert A, Stein, Evan

Journal:

The American Journal of Cardiology

Year:

2019

File:

PDF, 634 KB

2019

74

Effects of Renal Impairment on the Pharmacokinetics, Efficacy, and Safety of Inclisiran: An Analysis of the ORION-7 and ORION-1 Studies

Wright, R. Scott, Collins, Michael G., Stoekenbroek, Robert M., Robson, Richard, Wijngaard, Peter L.J., Landmesser, Ulf, Leiter, Lawrence A., Kastelein, John J.P., Ray, Kausik K., Kallend, David

Journal:

Mayo Clinic Proceedings

Year:

2019

Language:

english

File:

PDF, 722 KB

english, 2019

75

Effect of inclisiran, the siRNA against PCSK9, on platelets, immune cells and immunological biomarkers - a pre-specified analysis from ORION-1

Landmesser, Ulf, Haghikia, Arash, Leiter, Lawrence A, Wright, R Scott, Kallend, David, Wijngaard, Peter, Stoekenbroek, Robert, Kastelein, John J P, Ray, Kausik K

Journal:

Cardiovascular Research

Year:

2020

File:

PDF, 899 KB

2020

76

Efficacy and Safety of Alirocumab inÂ Adults With Homozygous FamilialÂ Hypercholesterolemia

Blom, Dirk J., Harada-Shiba, Mariko, Rubba, Paolo, Gaudet, Daniel, Kastelein, John J.P., Charng, Min-Ji, Pordy, Robert, Donahue, Stephen, Ali, Shazia, Dong, Yuping, Khilla, Nagwa, Banerjee, Poulabi, B

Journal:

Journal of the American College of Cardiology

Year:

2020

File:

PDF, 595 KB

2020

77

The Efficacy and Safety of Evinacumab in Homozygous Familial Hypercholesterolemia Patients with Little to No Low-Density Lipoprotein Receptor Activity

Rosenson, Robert, Raal, Frederick, Reeskamp, Laurens, Kastelein, John, Baum, Seth, Ali, Shazia, Banerjee, Poulabi, Chan, Kuo-Chen, Gipe, Daniel, Pordy, Robert, Gaudet, Daniel

Journal:

Journal of Clinical Lipidology

Year:

2020

File:

PDF, 108 KB

2020