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51

Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers

Kerkelä, E, Ala-aho, R, Jeskanen, L, Lohi, J, Grénman, R, M-Kähäri, V, Saarialho-Kere, U

Journal:

British Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 460 KB

english, 2001

52

The -Catenin/T-Cell Factor/Lymphocyte Enhancer Factor Signaling Pathway Is Required for Normal and Stress-Induced Cardiac Hypertrophy

Chen, X., Shevtsov, S. P., Hsich, E., Cui, L., Haq, S., Aronovitz, M., Kerkela, R., Molkentin, J. D., Liao, R., Salomon, R. N., Patten, R., Force, T.

Journal:

Molecular and Cellular Biology

Year:

2006

Language:

english

File:

PDF, 539 KB

english, 2006

53

Neuronostatin, a Novel Peptide Encoded by Somatostatin Gene, Regulates Cardiac Contractile Function and Cardiomyocyte Survival

Vainio, L., Perjes, A., Ryti, N., Magga, J., Alakoski, T., Serpi, R., Kaikkonen, L., Piuhola, J., Szokodi, I., Ruskoaho, H., Kerkela, R.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

54

Identification of PKCalpha Isoform-Specific Effects in Cardiac Myocytes Using Antisense Phosphorothioate Oligonucleotides

Journal:

Molecular Pharmacology

Year:

2002

Language:

english

File:

PDF, 350 KB

english, 2002

55

Mitogen-activated Protein Kinases p38 and ERK 1/2 Mediate the Wall Stress-induced Activation of GATA-4 Binding in Adult Heart

Tenhunen, O., Sarman, B., Kerkela, R., Szokodi, I., Papp, L., Toth, M., Ruskoaho, H.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 757 KB

english, 2004

56

GATA-4 Is a Nuclear Mediator of Mechanical Stretch-activated Hypertrophic Program

Pikkarainen, S., Tokola, H., Majalahti-Palviainen, T., Kerkela, R., Hautala, N., Bhalla, S. S., Charron, F., Nemer, M., Vuolteenaho, O., Ruskoaho, H.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 511 KB

english, 2003

57

The association between erectile dysfunction, depressive symptoms and testosterone levels among middle-aged men

Suija, K., Kerkela, M., Rajala, U., Jokelainen, J., Laakso, M., Harkonen, P., Keinanen-Kiukaanniemi, S., Timonen, M.

Journal:

Scandinavian Journal of Public Health

Year:

2014

Language:

english

File:

PDF, 343 KB

english, 2014

58

Distinct Roles of Mitogen-activated Protein Kinase Pathways in GATA-4 Transcription Factor-mediated Regulation of B-type Natriuretic Peptide Gene

Kerkelä, Risto, Pikkarainen, Sampsa, Majalahti-Palviainen, Theresa, Tokola, Heikki, Ruskoaho, Heikki

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 778 KB

english, 2002

59

Functionally Opposing Roles of Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase in the Regulation of Cardiac Contractility

Szokodi, I., Kerkela, R., Kubin, A.-M., Sarman, B., Pikkarainen, S., Konyi, A., Horvath, I. G., Papp, L., Toth, M., Skoumal, R., Ruskoaho, H.

Journal:

Year:

2008

Language:

english

File:

PDF, 562 KB

english, 2008

60

Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection

Kerkela, R., Karsikas, S., Szabo, Z., Serpi, R., Magga, J., Gao, E., Alitalo, K., Anisimov, A., Sormunen, R., Pietila, I., Vainio, L., Koch, W. J., Kivirikko, K. I., Myllyharju, J., Koivunen, P.

Journal:

Molecular and Cellular Biology

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

61

Collagen XV Is Necessary for Modeling of the Extracellular Matrix and Its Deficiency Predisposes to Cardiomyopathy

Rasi, K., Piuhola, J., Czabanka, M., Sormunen, R., Ilves, M., Leskinen, H., Rysa, J., Kerkela, R., Janmey, P., Heljasvaara, R., Peuhkurinen, K., Vuolteenaho, O., Ruskoaho, H., Vajkoczy, P., Pihlajanie

Journal:

Circulation Research

Year:

2010

Language:

english

File:

PDF, 13.28 MB

english, 2010

62

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype

Pekkanen-Mattila, M., Chapman, H., Kerkela, E., Suuronen, R., Skottman, H., Koivisto, A.-P., Aalto-Setala, K.

Journal:

Experimental Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 835 KB

english, 2010

63

Serine 58 of 14-3-3 Is a Molecular Switch Regulating ASK1 and Oxidant Stress-Induced Cell Death

Zhou, J., Shao, Z., Kerkela, R., Ichijo, H., Muslin, A. J., Pombo, C., Force, T.

Journal:

Molecular and Cellular Biology

Year:

2009

Language:

english

File:

PDF, 1.70 MB

english, 2009

64

The Effect of Human and Mouse Fibroblast Feeder Cells on Cardiac Differentiation of Human Pluripotent Stem Cells

Pekkanen-Mattila, Mari, Ojala, Marisa, Kerkelä, Erja, Rajala, Kristiina, Skottman, Heli, Aalto-Setälä, Katriina

Journal:

Stem Cells International

Year:

2012

Language:

english

File:

PDF, 2.85 MB

english, 2012

65

Mechanisms of Cardiac Dysfunction Associated With Tyrosine Kinase Inhibitor Cancer Therapeutics

Chen, M. H., Kerkela, R., Force, T.

Journal:

Year:

2008

Language:

english

File:

PDF, 589 KB

english, 2008

66

2D and 3D Self-Assembling Nanofiber Hydrogels for Cardiomyocyte Culture

Ikonen, Liisa, Kerkelä, Erja, Metselaar, Gerald, Stuart, Marc C. A., de Jong, Menno R., Aalto-Setälä, Katriina

Journal:

BioMed Research International

Year:

2013

Language:

english

File:

PDF, 3.81 MB

english, 2013

67

Key roles of endothelin-1 and p38 MAPK in the regulation of atrial stretch response

Kerkela, R., Ilves, M., Pikkarainen, S., Tokola, H., Ronkainen, V.-P., Majalahti, T., Leppaluoto, J., Vuolteenaho, O., Ruskoaho, H.

Journal:

AJP Regulatory Integrative and Comparative Physiology

Year:

2011

Language:

english

File:

PDF, 819 KB

english, 2011

68

ROCK2 allelic variants are not associated with pre-eclampsia susceptibility in the Finnish population

Peterson, H., Laivuori, H., Kerkela, E., Jiao, H., Hiltunen, L., Heino, S., Tiala, I., Knuutila, S., Rasi, V., Kere, J., Kivinen, K.

Journal:

Molecular Human Reproduction

Year:

2009

Language:

english

File:

PDF, 208 KB

english, 2009

69

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

Perjés, Ábel, Kilpiö, Teemu, Ulvila, Johanna, Magga, Johanna, Alakoski, Tarja, Szabó, Zoltán, Vainio, Laura, Halmetoja, Eveliina, Vuolteenaho, Olli, Petäjä-Repo, Ulla, Szokodi, István, Kerkelä, Risto

Journal:

Basic Research in Cardiology

Year:

2016

Language:

english

File:

PDF, 771 KB

english, 2016

70

-Adrenergic Agonists Mediate Enhancement of 1-Adrenergic Receptor N-terminal Cleavage and Stabilization In Vivo and In Vitro

Hakalahti, A. E., Khan, H., Vierimaa, M. M., Pekkala, E. H., Lackman, J. J., Ulvila, J., Kerkela, R., Petaja-Repo, U. E.

Journal:

Molecular Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.84 MB

english, 2013

71

Molecular Scaffolds Regulate Bidirectional Crosstalk Between Wnt and Classical Seven-Transmembrane Domain Receptor Signaling Pathways

Force, T., Woulfe, K., Koch, W. J., Kerkela, R.

Journal:

Year:

2007

Language:

english

File:

PDF, 766 KB

english, 2007

72

The effects of culture conditions on the functionality of efficiently obtained mesenchymal stromal cells from human cord blood

Laitinen, Anita, Lampinen, Milla, Liedtke, Stefanie, Kilpinen, Lotta, Kerkelä, Erja, Sarkanen, Jertta-Riina, Heinonen, Tuula, Kogler, Gesine, Laitinen, Saara

Journal:

Year:

2016

Language:

english

File:

PDF, 1.72 MB

english, 2016

73

Natriuretic Peptides in the Regulation of Cardiovascular Physiology and Metabolic Events

Kerkelä, Risto, Ulvila, Johanna, Magga, Johanna

Journal:

Journal of the American Heart Association

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

74

The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity

Cui, Li-li, Kerkelä, Erja, Bakreen, Abdulhameed, Nitzsche, Franziska, Andrzejewska, Anna, Nowakowski, Adam, Janowski, Miroslaw, Walczak, Piotr, Boltze, Johannes, Lukomska, Barbara, Jolkkonen, Jukka

Journal:

Stem Cell Research & Therapy

Year:

2015

Language:

english

File:

PDF, 1018 KB

english, 2015

75

Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells

Kerkelä, Erja, Laitinen, Anita, Räbinä, Jarkko, Valkonen, Sami, Takatalo, Maarit, Larjo, Antti, Veijola, Johanna, Lampinen, Milla, Siljander, Pia, Lehenkari, Petri, Alfthan, Kaija, Laitinen, Saara

Journal:

Year:

2016

Language:

english

File:

PDF, 515 KB

english, 2016

76

Differential Clearance of Rat and Human Bone Marrow-Derived Mesenchymal Stem Cells From the Brain After Intra-arterial Infusion in Rats

Khabbal, Joonas, Kerkelä, Erja, Mitkari, Bhimashankar, Raki, Mari, Nystedt, Johanna, Mikkonen, Ville, Bergström, Kim, Laitinen, Saara, Korhonen, Matti, Jolkkonen, Jukka

Journal:

Cell Transplantation

Year:

2015

Language:

english

File:

PDF, 687 KB

english, 2015

77

Direct cardiac actions of erythropoietin (EPO): effects on cardiac contractility, BNP secretion and ischaemia/reperfusion injury

Piuhola, Jarkko, Kerkelä, Risto, Keenan, Jacqueline I., Hampton, Mark B., Richards, A. Mark, Pemberton, Chris J.

Journal:

Clinical Science

Year:

2008

Language:

english

File:

PDF, 725 KB

english, 2008

78

Real-Time Label-Free Monitoring of Nanoparticle Cell Uptake

Suutari, Teemu, Silen, Tiina, S˛en Karaman, Didem, Saari, Heikki, Desai, Diti, Kerkelä, Erja, Laitinen, Saara, Hanzlikova, Martina, Rosenholm, Jessica M., Yliperttula, Marjo, Viitala, Tapani

Journal:

Year:

2016

Language:

english

File:

PDF, 1.80 MB

english, 2016

79

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

Räsänen, Markus, Degerman, Joni, Nissinen, Tuuli A., Miinalainen, Ilkka, Kerkelä, Risto, Siltanen, Antti, Backman, Janne T., Mervaala, Eero, Hulmi, Juha J., Kivelä, Riikka, Alitalo, Kari

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.34 MB

english, 2016

80

Response to Letter to the Editor: Adenosine Producing Mesenchymal Stromal Cells

Journal:

Year:

2016

Language:

english

File:

PDF, 70 KB

english, 2016

81

Individual experiences following a 6-month exercise intervention: A qualitative study

Kerkelä, Ellen Staveborg, Jonsson, Linus, Lindwall, Magnus, Strand, Jennifer

Journal:

International Journal of Qualitative Studies on Health and Well-Being

Year:

2015

Language:

english

File:

PDF, 672 KB

english, 2015

82

Phospholipid composition of packed red blood cells and that of extracellular vesicles show a high resemblance and stability during storage

Laurén, Eva, Tigistu-Sahle, Feven, Valkonen, Sami, Westberg, Melissa, Valkeajärvi, Anne, Eronen, Juha, Siljander, Pia, Pettilä, Ville, Käkelä, Reijo, Laitinen, Saara, Kerkelä, Erja

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2017

Language:

english

File:

PDF, 1.58 MB

english, 2017

83

Primary Myocardial Fibrosis as an Alternative Phenotype Pathway of Inherited Cardiac Structural Disorders

Junttila, M. Juhani, Holmström, Lauri, Pylkäs, Katri, Mantere, Tuomo, Kaikkonen, Kari, Porvari, Katja, Kortelainen, Marja-Leena, Pakanen, Lasse, Kerkelä, Risto, Myerburg, Robert J., Huikuri, Heikki V.

Journal:

Year:

2018

Language:

english

File:

PDF, 354 KB

english, 2018

84

Transcriptome Profiling of Human Pre-Implantation Development

Zhang, Pu, Zucchelli, Marco, Bruce, Sara, Hambiliki, Fredwell, Stavreus-Evers, Anneli, Levkov, Lev, Skottman, Heli, Kerkelä, Erja, Kere, Juha, Hovatta, Outi, Laudet, Vincent

Journal:

Year:

2009

Language:

english

File:

PDF, 482 KB

english, 2009

85

Apelin Increases Cardiac Contractility via Protein Kinase Cε- and Extracellular Signal-Regulated Kinase-Dependent Mechanisms

Perjés, Ábel, Skoumal, Réka, Tenhunen, Olli, Kónyi, Attila, Simon, Mihály, Horváth, Iván G., Kerkelä, Risto, Ruskoaho, Heikki, Szokodi, István, Bader, Michael

Journal:

Year:

2014

Language:

english

File:

PDF, 636 KB

english, 2014

86

The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression

Kelloniemi, Annina, Szabo, Zoltan, Serpi, Raisa, Näpänkangas, Juha, Ohukainen, Pauli, Tenhunen, Olli, Kaikkonen, Leena, Koivisto, Elina, Bagyura, Zsolt, Kerkelä, Risto, Leosdottir, Margret, Hedner, Th

Journal:

Year:

2015

Language:

english

File:

PDF, 8.97 MB

english, 2015

87

Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22

Hyvärinen, Kati, Holopainen, Minna, Skirdenko, Vita, Ruhanen, Hanna, Lehenkari, Petri, Korhonen, Matti, Käkelä, Reijo, Laitinen, Saara, Kerkelä, Erja

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 1.21 MB

english, 2018

88

1211Genetic background of sudden cardiac death caused by idiopathic myocardial fibrosis

Holmstrom, L., Pylkas, K., Mantere, T., Porvari, K., Kortelainen, M.L., Pakanen, L., Kerkela, R., Huikuri, H., Junttila, J.

Journal:

European Heart Journal

Year:

2017

Language:

english

File:

PDF, 180 KB

english, 2017

89

GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice

Zhou, Jibin, Lal, Hind, Chen, Xiongwen, Shang, Xiying, Song, Jianliang, Li, Yingxin, Kerkela, Risto, Doble, Bradley W., MacAulay, Katrina, DeCaul, Morgan, Koch, Walter J., Farber, John, Woodgett, Jame

Journal:

Journal of Clinical Investigation

Year:

2010

Language:

english

File:

PDF, 2.02 MB

english, 2010

90

Pathways from parental mental disorders to offspring's work disability due to depressive or anxiety disorders in early adulthood-The 1987 Finnish Birth Cohort

Halonen, Jaana I., Merikukka, Marko, Gissler, Mika, Kerkelä, Martta, Virtanen, Marianna, Ristikari, Tiina, Hiilamo, Heikki, Lallukka, Tea

Journal:

Depression and Anxiety

Year:

2018

Language:

english

File:

PDF, 546 KB

english, 2018

91

Red blood cell transfusion in southern Finland from 2011 to 2016: a quality audit

Laurén, E., Vikatmaa, L., Kerkelä, E., Kivipuro, T., Krusius, T., Syrjälä, M., Ihalainen, J., Pettilä, V.

Journal:

Transfusion Medicine

Year:

2018

Language:

english

File:

PDF, 373 KB

english, 2018

92

Inhibition of cardiomyocyte Sprouty1 protects from cardiac ischemia–reperfusion injury

Alakoski, Tarja, Ulvila, Johanna, Yrjölä, Raisa, Vainio, Laura, Magga, Johanna, Szabo, Zoltan, Licht, Jonathan D., Kerkelä, Risto

Journal:

Basic Research in Cardiology

Year:

2019

Language:

english

File:

PDF, 1.47 MB

english, 2019

93

P3823The role of genetics in apparently acquired non-ischemic cardiomyopathies leading to sudden cardiac death

Holmstrom, L, Pylkas, K, Mantere, T, Porvari, K, Pakanen, L, Kortelainen, M L, Kerkela, R, Huikuri, H, Junttila, M J

Journal:

European Heart Journal

Year:

2018

Language:

english

File:

PDF, 185 KB

english, 2018

94

Determinants of long-term unemployment in early adulthood: A Finnish birth cohort study

Lallukka, Tea, Kerkelä, Martta, Ristikari, Tiina, Merikukka, Marko, Hiilamo, Heikki, Virtanen, Marianna, Øverland, Simon, Gissler, Mika, Halonen, Jaana I.

Journal:

SSM - Population Health

Year:

2019

Language:

english

File:

PDF, 1.13 MB

english, 2019

95

In vivo demonstration of microscopic anisotropy in the human kidney using multidimensional diffusion MRI

Nery, Fabio, Szczepankiewicz, Filip, Kerkelä, Leevi, Hall, Matt G., Kaden, Enrico, Gordon, Isky, Thomas, David L., Clark, Chris A.

Journal:

Magnetic Resonance in Medicine

Year:

2019

Language:

english

File:

PDF, 723 KB

english, 2019

96

The Finnish psychiatric birth cohort consortium (PSYCOHORTS) – content, plans and perspectives

Filatova, S., Gyllenberg, D., Sillanmäki, L., Suominen, A., Hinkka-Yli-Salomäki, S., Kaljonen, A., Kerkelä, M., Keski-Säntti, M., Ristikari, T., Lagström, H., Hurtig, T., Miettunen, J., Surcel, H.-M.,

Journal:

Nordic Journal of Psychiatry

Year:

2019

Language:

english

File:

PDF, 1.11 MB

english, 2019

97

The Finnish psychiatric birth cohort consortium (PSYCOHORTS) – content, plans and perspectives

Filatova, S., Gyllenberg, D., Sillanmäki, L., Suominen, A., Hinkka-Yli-Salomäki, S., Kaljonen, A., Kerkelä, M., Keski-Säntti, M., Ristikari, T., Lagström, H., Hurtig, T., Miettunen, J., Surcel, H.-M.,

Journal:

Nordic Journal of Psychiatry

Year:

2019

File:

PDF, 1.11 MB

2019

98

Novel Screening Method Identifies PI3Kα, mTOR, and IGF1R as Key Kinases Regulating Cardiomyocyte Survival

Elmadani, Manar, Khan, Suleiman, Tenhunen, Olli, Magga, Johanna, Aittokallio, Tero, Wennerberg, Krister, Kerkelä, Risto

Journal:

Journal of the American Heart Association

Year:

2019

File:

PDF, 1.79 MB

2019

99

Validation and noise robustness assessment of microscopic anisotropy estimation with clinically feasible double diffusion encoding MRI

Kerkelä, Leevi, Henriques, Rafael Neto, Hall, Matt G., Clark, Chris A., Shemesh, Noam

Journal:

Magnetic Resonance in Medicine

Year:

2019

File:

PDF, 1.44 MB

2019

100

Mortality by diseases and medical conditions in the offspring of parents with severe mental illness

Protsenko, Maria, Kerkelä, M., Miettunen, J., Auvinen, J., Järvelin, M.-R., Gissler, M., Veijola, J.

Journal:

Social Psychiatry and Psychiatric Epidemiology

Year:

2019

Language:

english

File:

PDF, 837 KB

english, 2019