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51

Acute effects of ethanol on the transfer of nicotine and two dietary carcinogens in human placental perfusion

Jenni Veid, Vesa Karttunen, Kirsi Myöhänen, Päivi Myllynen, Seppo Auriola, Toivo Halonen, Kirsi Vähäkangas

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 597 KB

english, 2011

52

32P-HPLC analysis of N1-(2-carboxy-2-hydroxyethyl)deoxyadenosine: A DNA adduct of the acrylamide-derived epoxide glycidamide

Natalia Kotova, Tina Jurén, Kirsi Myöhänen, Michael Cornelius, Lilianne Abramsson-Zetterberg, Josefin Backman, Ulrike Menzel, Per Rydberg, Leif Kronberg, Kirsi Vähäkangas, Dan Segerbäck

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 312 KB

english, 2011

53

Fate of the teratogenic and carcinogenic ochratoxin A in human perfused placenta

Chit Shing Jackson Woo, Heidi Partanen, Päivi Myllynen, Kirsi Vähäkangas, Hani El-Nezami

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 566 KB

english, 2012

54

Acute effects of ethanol on transplacental transfer

Vesa Karttunen, Jenni Veid, Kirsi Myöhänen, Päivi Myllynen, Seppo Auriola, Toivo Halonen, Kirsi Vähäkangas

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 88 KB

english, 2012

55

Comparison of anti-p53 antibodies in immunoblotting

Miia Turpeinen, Raisa Serpi, Mika Rahkolin, Kirsi Vähäkangas

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 183 KB

english, 2002

56

Benzo[a]pyrene-DNA-adducts and monooxygenase activities in mice treated with benzo[a]pyrene, cigarette smoke or cigarette smoke condensate

Nina Bjelogrlic, Mumtaz Iscan, Hannu Raunio, Olavi Pelkonen, Kirsi Vähäkangas

Journal:

Chemico-Biological Interactions

Year:

1989

Language:

english

File:

PDF, 548 KB

english, 1989

57

Placental transfer and metabolism: An overview of the experimental models utilizing human placental tissue

Päivi Myllynen, Kirsi Vähäkangas

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 217 KB

english, 2013

58

Apoptosis in neurotoxicity of fumonisin B1

Kai Savolainen, Helene Stockmann-Juvala, Jonne Naarala, Jarkko Loikkanen, Kirsi Vähäkangas

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 87 KB

english, 2006

59

Estrogenicity of PhIP and the effect of growth medium on the expression of estrogenic responses in MCF-7 cells

Elina Immonen, Kirsi Vähäkangas, Raisa Serpi, Päivi Myllynen

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 73 KB

english, 2007

60

Transplacental transfer of NDMA in human placental perfusion and DNA adduct formation in the placenta

Kirsi Annola, Vesa Karttunen, Päivi Luukkainen, Dan Segerbäck, Kirsi Vähäkangas

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

61

ABCG2 decreases the placental transfer of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Paivi Myllynen, Maria Kummu, Rauna Pirila, Anni Lastumaki, Kirsi Vahakangas

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 87 KB

english, 2007

62

Benzo(a)pyrene induced apoptosis in MCF-7 cells

Marjo Tampio, Piia Markkanen, Maija-Riitta Hirvonen, Kirsi H. Vähäkangas

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 89 KB

english, 2008

63

Transplacental transfer of acrylamide and glycidamide are comparable to that of antipyrine in perfused human placenta

Kirsi Annola, Vesa Karttunen, Pekka Keski-Rahkonen, Päivi Myllynen, Dan Segerbäck, Seppo Heinonen, Kirsi Vähäkangas

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

64

Induction of PUMA-α and down-regulation of PUMA-β expression is associated with benzo(a)pyrene-induced apoptosis in MCF-7 cells

Marjo Tampio, Piia Markkanen, Katja A. Puttonen, Eveliina Hagelberg, Hannu Heikkinen, Kati Huhtinen, Jarkko Loikkanen, Maija-Riitta Hirvonen, Kirsi H. Vähäkangas

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

65

Pb2+-induced toxicity is associated with p53-independent apoptosis and enhanced by glutamate in GT1–7 neurons

Jarkko Loikkanen, Katerina Chvalova, Jonne Naarala, Kirsi H. Vähäkangas, Kai M. Savolainen

Journal:

Toxicology Letters

Year:

2003

Language:

english

File:

PDF, 284 KB

english, 2003

66

Ethical aspects in tissue research: thematic analysis of ethical statements to the research ethics committee

Halkoaho, Arja, Pietilä, Anna-Maija, Vesalainen, Mari, Vähäkangas, Kirsi

Journal:

BMC Medical Ethics

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

67

The fate and effects of xenobiotics in human placenta

Myllynen, Päivi, Pasanen, Markku, Vähäkangas, Kirsi

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2007

Language:

english

File:

PDF, 228 KB

english, 2007

68

Estimation of health risk by using toxicokinetic modelling: A case study of polychlorinated biphenyl PCB153

Abass, Khaled, Huusko, Antti, Nieminen, Pentti, Myllynen, Päivi, Pelkonen, Olavi, Vahakangas, Kirsi, Rautio, Arja

Journal:

Journal of Hazardous Materials

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

69

Scientific integrity: critical issues in environmental health research

Domenico Franco Merlo, Kirsi Vahakangas, Lisbeth E Knudsen

Journal:

Environmental Health

Year:

2008

Language:

english

File:

PDF, 536 KB

english, 2008

70

Polychlorinated biphenyls (PCBs) in relation to secondary sex ratio – A systematic review of published studies

Nieminen, Pentti, Lehtiniemi, Heli, Huusko, Antti, Vähäkangas, Kirsi, Rautio, Arja

Journal:

Year:

2013

Language:

english

File:

PDF, 284 KB

english, 2013

71

Exposure to ethanol and nicotine induces stress responses in human placental BeWo cells

K. Repo, Jenni, Pesonen, Maija, Mannelli, Chiara, Vähäkangas, Kirsi, Loikkanen, Jarkko

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 2.52 MB

english, 2014

72

Preservation, induction or incorporation of metabolism into the in vitro cellular system − Views to current opportunities and limitations

Pelkonen, Olavi, Turpeinen, Miia, Hakkola, Jukka, Abass, Khaled, Pasanen, Markku, Raunio, Hannu, Vähäkangas, Kirsi

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 308 KB

english, 2013

73

Synchronous fluorescence spectrophotometry to detect benzo(a)pyrene-DNA adducts in human tissues

Vähäkangas, Kirsi, Trivers, Glennwood, Rowe, Marilyn, Harris, Curtis C.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1985

Language:

english

File:

PDF, 98 KB

english, 1985

74

Biological monitoring among coke oven workers

Haugen, Aage, Becher, Georg, Benestad, Christel, Vahakangas, Kirsi, Trivers, Glennwood E., Harris, Curtis C.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1985

Language:

english

File:

PDF, 113 KB

english, 1985

75

Chloropicrin-induced toxic responses in human lung epithelial cells

Pesonen, Maija, Häkkinen, Merja, Rilla, Kirsi, Juvonen, Risto, Kuitunen, Tapio, Pasanen, Markku, Vähäkangas, Kirsi

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 2.25 MB

english, 2014

76

The distribution of benzo(a)pyrene and its metabolites in isolated perfused lung and liver

Vähäkangas, Kirsi

Journal:

Toxicology Letters

Year:

1979

Language:

english

File:

PDF, 394 KB

english, 1979

77

Retrovirus-mediated stable expression of human CYP2A6 in mammalian cells

Salonpää, Pirkko, Hakkola, Jukka, Pasanen, Markku, Pelkonen, Olavi, Vähäkangas, Kirsi, Battula, Narayana, Nouso, Kazuhiro, Raunio, Hannu

Journal:

European Journal of Pharmacology: Environmental Toxicology and Pharmacology

Year:

1993

Language:

english

File:

PDF, 715 KB

english, 1993

78

Towards toxicity assessment without animals

Heinonen, Tuula, Tähti, Hanna, Vähäkangas, Kirsi, Blaauboer, Bas J.

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 181 KB

english, 2013

79

Detection of Benzo[a]pyrene Diol Epoxide--DNA Adducts in Peripheral Blood Lymphocytes and Antibodies to the Adducts in Serum from Coke Oven Workers

Curtis C. Harris, Kirsi Vahakangas, Mark J. Newman, Glennwood E. Trivers, Abulkalam Shamsuddin, Nuntia Sinopoli, Dean L. Mann and William E. Wright

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 968 KB

english, 1985

80

Detection of 8,9-Dihydro-(7′-Guanyl)-9-Hydroxyaflatoxin B1 in Human Urine

Herman Autrup, Johnston Wakhisi, Kirsi Vahakangas, A. Wasunna and Curtis C. Harris

Journal:

Environmental Health Perspectives

Year:

1985

Language:

english

File:

PDF, 220 KB

english, 1985

81

Benzo(a)pyrene Diolepoxide-DNA Adducts Detected by Synchronous Fluorescence Spectrophotometry

Kirsi Vahakangas, Glennwood Trivers, Marilyn Rowe and Curtis C. Harris

Journal:

Environmental Health Perspectives

Year:

1985

Language:

english

File:

PDF, 264 KB

english, 1985

82

Developmental expression of drug metabolizing enzymes and transporter proteins in human placenta and fetal tissues

Myllynen, Päivi, Immonen, Elina, Kummu, Maria, Vähäkangas, Kirsi

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2009

Language:

english

File:

PDF, 670 KB

english, 2009

83

Biomarkers in Toxicology || Biomarkers of toxicity in human placenta

Vähäkangas, Kirsi

Year:

2014

Language:

english

File:

PDF, 1.87 MB

english, 2014

84

The effects of the herbicide diuron in MCF-7 and Bewo cells

Huovinen, Marjo, Loikkanen, Jarkko, Naarala, Jonne, Vähäkangas, Kirsi

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 72 KB

english, 2014

85

Research ethics in the post-genomic era

Vähäkangas, Kirsi

Journal:

Environmental and Molecular Mutagenesis

Year:

2013

Language:

english

File:

PDF, 121 KB

english, 2013

86

An applied synchronous fluorescence spectrophotometric assay to study benzo[a]pyrene-diolepoxide-DNA adducts

Vahakangas, Kirsi, Haugen, Aage, Harris, Curtis C.

Journal:

Year:

1985

Language:

english

File:

PDF, 618 KB

english, 1985

87

p 53 Protein expression is correlated with benzo[ a ]pyrene-DNA adducts in carcinoma cell lines

Rämet, Mika, Castrén, Katariina, Järvinen, Kaisu, Pekkala, Katja, Turpeenniemi-Hujanen, Taina, Soini, Ylermi, Pääkkö, Paavo, Vähäkangas, Kirsi

Journal:

Year:

1995

Language:

english

File:

PDF, 4.52 MB

english, 1995

88

O 6 -Methylguanine-DNA Methyltransferase and uracil DNA glycosylase in human broncho-alveolar lavage cells and peripheral blood mononuclear cells from tobacco smokers and non-smokers

Vähäkangas, Kirsi, Trivers, Glennwood E., Plummer, Simon, Hayes, Richard B., Krokan, Hans, Rowe, Marilyn, Swartz, Rodney P., Yeager, Henry, Harris, Curtis C.

Journal:

Year:

1991

Language:

english

File:

PDF, 634 KB

english, 1991

89

SHORT COMMUNICATION: TPA decreases the p53 response to benzo[ a ]pyrene-DNA adducts in vivo in mouse skin

Tapiainen, Terhi, Järvinen, Kaisu, Pääkkö, Paavo, Bjelogrlic, Nina, Vähäkangas, Kirsi

Journal:

Year:

1996

Language:

english

File:

PDF, 2.19 MB

english, 1996

90

Toxicity of diuron in human cancer cells

Huovinen, Marjo, Loikkanen, Jarkko, Naarala, Jonne, Vähäkangas, Kirsi

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

91

Human placental cell and tissue uptake of doxorubicin and its liposomal formulations

Soininen, Suvi K., Repo, Jenni K., Karttunen, Vesa, Auriola, Seppo, Vähäkangas, Kirsi H., Ruponen, Marika

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 497 KB

english, 2015

92

Transcriptomic Analysis of Human Primary Bronchial Epithelial Cells after Chloropicrin Treatment

Pesonen, Maija, Storvik, Markus, Kokkola, Tarja, Rysä, Jaana, Vähäkangas, Kirsi, Pasanen, Markku

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 5.50 MB

english, 2015

93

Binding of polycyclic aromatic hydrocarbons to DNA: Comparison with mutagenesis and tumorigenesis

Pelkonen, Olavi, Vähäkangas, Kirsi, Nebert, Daniel W.

Journal:

Journal of Toxicology and Environmental Health

Year:

1980

Language:

english

File:

PDF, 985 KB

english, 1980

94

Analysis of nitromethane from samples exposed in vitro to chloropicrin by stable isotope dilution headspace gas chromatography with mass spectrometry

Halme, Mia, Pesonen, Maija, Grandell, Toni, Kuula, Matti, Pasanen, Markku, Vähäkangas, Kirsi, Vanninen, Paula

Journal:

Journal of Separation Science

Year:

2015

Language:

english

File:

PDF, 508 KB

english, 2015

95

Applying human and pig hepatic in vitro experiments for sulfur mustard study: Screening and identification of metabolites by liquid chromatography/tandem mass spectrometry

Halme, Mia, Pesonen, Maija, Hakala, Ullastiina, Pasanen, Markku, Vähäkangas, Kirsi, Vanninen, Paula

Journal:

Rapid Communications in Mass Spectrometry

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

96

Expression of p53 and Proliferating Cell Nuclear Antigen in Lichen Sclerosus et Atrophicus With Different Histological Features

Soini, Ylermi, Pääkkö, Paavo, Vähäkangas, Kirsi, Vuopala, Salme, Lehto, Veli-Pekka

Journal:

International Journal of Gynecological Pathology

Year:

1994

File:

PDF, 419 KB

1994

97

Molecular targets of chloropicrin in human airway epithelial cells

Pesonen, Maija, Rysä, Jaana, Storvik, Markus, Rilla, Kirsi, Pasanen, Markku, Vähäkangas, Kirsi

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

98

Cytochrome P450 3A Expression in the Human Fetal Liver: Evidence that CYP3A5 Is Expressed in Only a Limited Number of Fetal Livers

Hakkola, Jukka, Raunio, Hannu, Purkunen, Raija, Saarikoski, Seppo, Vähäkangas, Kirsi, Pelkonen, Olavi, Edwards, Robert J., Boobis, Alan R., Pasanen, Markku

Journal:

Biology of the Neonate

Year:

2001

Language:

english

File:

PDF, 281 KB

english, 2001

99

Transfer and metabolism of diuron in human placenta

Mohammed, Ali, Karttunen, Vesa, Huuskonen, Pasi, Huovinen, Marjo, Auriola, Seppo, Vähäkangas, Kirsi

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

100

The MATEX cohort – a Finnish population register birth cohort to study health effects of prenatal exposures

Rumrich, Isabell K., Vähäkangas, Kirsi, Viluksela, Matti, Gissler, Mika, Surcel, Heljä-Marja, de Ruyter, Hanna, Jokinen, Jukka, Hänninen, Otto

Journal:

BMC Public Health

Year:

2017

Language:

english

File:

PDF, 1.91 MB

english, 2017