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51

Extract of Ginkgo biloba induces glutamate cysteine ligase catalytic subunit (GCLC)

Xiao-Ping Liu, Christopher E. P. Goldring, Hai-Yi Wang, Ian M. Copple, Neil R. Kitteringham, B. Kevin Park, Wei Wei

Journal:

Phytotherapy Research

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

52

The effect of liver cirrhosis on the pharmacokinetics of phenprocoumon

N. R. Kitteringham, L. Büstgens, E. Brundert, S. Mineshita, E. E. Ohnhaus

Journal:

European Journal of Clinical Pharmacology

Year:

1984

Language:

english

File:

PDF, 677 KB

english, 1984

53

The effect of wheat bran on the pharmacokinetics of phenprocoumon in normal volunteers

N. R. Kitteringham, S. Mineshita, E. E. Ohnhaus

Journal:

Journal of Molecular Medicine

Year:

1985

Language:

english

File:

PDF, 341 KB

english, 1985

54

Trans-anastomotic tubes reduce the need for central venous access and parenteral nutrition in infants with congenital duodenal obstruction

N. J. Hall, M. Drewett, R. A. Wheeler, D. M. Griffiths, L. J. Kitteringham, D. M. Burge

Journal:

Pediatric Surgery International

Year:

2011

Language:

english

File:

PDF, 164 KB

english, 2011

55

The demonstration of serum interleukin-8 and superoxide dismutase in Adamantiades-Behçet’s disease

L. M. Wang, N. Kitteringham, S. Mineshita, J. Z. Wang, Y. Nomura, Y. Koike, E. Miyashita

Journal:

Archives of Dermatological Research

Year:

1997

Language:

english

File:

PDF, 89 KB

english, 1997

56

Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice

Laura E. Randle, Chris E.P. Goldring, Craig A. Benson, Peter N. Metcalfe, Neil R. Kitteringham, B. Kevin Park, Dominic P. Williams

Journal:

Year:

2008

Language:

english

File:

PDF, 904 KB

english, 2008

57

2-Dimensional gel electrophoresis and MALDI-MS of cystic cervical metastasis from head and neck squamous cell carcinoma

H.L. Beer, R.E. Jenkins, D. Gutowska-Owsiak, L. Pazmany, M.A. Birchall, N.R. Kitteringham

Journal:

Clinical Otolaryngology (Blackwell)

Year:

2006

Language:

english

File:

PDF, 41 KB

english, 2006

58

Proteomic analysis of metastatic laryngeal squamous cell carcinoma : Abstracts of the Otorhinolaryngological Research Society Meeting Autumn Meeting 26th September 2008, UCL Ear Institute, Gray's Inn Road, London

P.W.A. Goodyear, M.T. Boyd, R. Jenkins, J. Hamlett, N. Kitteringham, T.M. Jones

Journal:

Clinical Otolaryngology (Blackwell)

Year:

2008

Language:

english

File:

PDF, 36 KB

english, 2008

59

Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity

Dean J Naisbitt, Sally J Hough, Helen J Gill, Munir Pirmohamed, Neil R Kitteringham, B Kevin Park

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 388 KB

english, 1999

60

α1-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice

L E Randle, J G Sathish, N R Kitteringham, I Macdonald, D P Williams, B K Park

Journal:

British Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

61

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Xue, Mingzhan, Rabbani, Naila, Momiji, Hiroshi, Imbasi, Precious, Anwar, M. Maqsud, Kitteringham, Neil, Park, B. Kevin, Souma, Tomokazu, Moriguchi, Takashi, Yamamoto, Masayuki

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 730 KB

english, 2012

62

Drug-Protein Conjugation and its Immunological Consequences

Kevin Park, B., Kitteringham, Neil R.

Journal:

Drug Metabolism Reviews

Year:

1990

Language:

english

File:

PDF, 964 KB

english, 1990

63

Hepatocellular response to chemical stress in CD-1 mice: Induction of early genes and γ-glutamylcysteine synthetase

Neil R. Kitteringham, Helen Powell, Yuri N. Clement, Charlotte C. Dodd, Justice N. Tettey, Munir Pirmohamed, Dennis A. Smith, Lesley I. McLellan, B. Kevin Park

Journal:

Year:

2000

Language:

english

File:

PDF, 561 KB

english, 2000

64

Drug metabolism and drug toxicity

B. Kevin Park, Neil R. Kitteringham, Jane R. Kenny, Munir Pirmohamed

Journal:

Inflammopharmacology

Year:

2001

Language:

english

File:

PDF, 247 KB

english, 2001

65

ChemInform Abstract: Novel Syntheses of Camptothecin Alkaloids. Part 2. Concise Synthesis of (S)-Camptothecins.

J. M. D. FORTUNAK, J. KITTERINGHAM, A. R. MASTROCOLA, M. MELLINGER, N. J. SISTI, J. L. WOOD, Z.-P. ZHUANG

Journal:

Year:

1996

File:

PDF, 34 KB

1996

66

The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity

B.Kevin Park, Munir Pirmohamed, Neil R. Kitteringham

Journal:

Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 4.62 MB

english, 1995

67

Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-κB

Alvin J.L. Chia, Christopher E. Goldring, Neil R. Kitteringham, Shi Quan Wong, Paul Morgan, B. Kevin Park

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 895 KB

english, 2010

68

Extract of Ginkgo biloba induces glutathione-S-transferase subunit-P1 in vitro

Xiao-Ping Liu, Christopher E.P. Goldring, Hai-Yi Wang, Ian M. Copple, Neil R. Kitteringham, B. Kevin Park

Journal:

Year:

2009

Language:

english

File:

PDF, 243 KB

english, 2009

69

Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening

Melissa A. Baxter, Cliff Rowe, Jane Alder, Sean Harrison, Karen Piper Hanley, B. Kevin Park, Neil R. Kitteringham, Chris E. Goldring, Neil A. Hanley

Journal:

Stem Cell Research

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

70

Analytical methodologies for determining the metabolism and disposition of PEGylated biopharmaceuticals

George T. Edge, Victoria L. Elliott, Neil R. Kitteringham, Marie Phelan, Lu-Yun Lian, Rob Webster, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

71

The role of the transcription factor Nrf2 in lipid metabolism in the liver

Joanne Walsh, Neil R. Kitteringham, Jules L. Griffin, Christopher E.P. Goldring, Samantha Williams, Helen Powell, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

72

The Effect of Straight Leg Raise Exercises after Lumbar Decompression Surgery — A Pilot Study

Christine Kitteringham

Journal:

Physiotherapy (Elsevier Science)

Year:

1996

Language:

english

File:

PDF, 1.95 MB

english, 1996

73

3 The pharmacology of the cytochrome P450 enzyme system

Neil R. Kitteringham, Munir Pirmohamed, B. Kevin Park

Journal:

Baillière's Clinical Anaesthesiology

Year:

1998

Language:

english

File:

PDF, 1.47 MB

english, 1998

74

A Simple Two-Step Synthesis of Indoles

Walkington, Andrew, Gray, Matthew, Hossner, Frank, Kitteringham, John, Voyle, Martyn

Journal:

Synthetic Communications

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

75

Drug-protein conjugates—VIII The metabolic fate of the dinitrophenyl hapten conjugated to albumin

N.R. Kitteringham, J.L. Maggs, S. Newby, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 764 KB

english, 1985

76

Drug-protein conjugates—X: The role of protein conjugation in the disposition of dinitrofluorobenzene

J.L. Maggs, N.R. Kitteringham, P.S. Grabowski, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 1.07 MB

english, 1986

77

Autoxidative formation of a chemically reactive intermediate from amodiaquine, a myelotoxin and hepatotoxin in man

J.L. Maggs, N.R. Kitteringham, A.M. Breckenridge, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 225 KB

english, 1987

78

Drug-protein conjugates—XIII: The disposition of the benzylpenicilloyl hapten conjugated to albumin

G. Christie, N.R. Kitteringham, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 800 KB

english, 1987

79

Drug-protein conjugates—XI disposition and immunogenicity of dinitrofluorobenzene, a model compound for the investigation of drugs as haptens

B.Kevin Park, Malcolm D. Tingle, Peter S. Grabowski, John W. Coleman, Neil R. Kitteringham

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 917 KB

english, 1987

80

Drug disposition and drug hypersensitivity

B. Kevin Park, John W. Coleman, Neil R. Kitteringham

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 1.06 MB

english, 1987

81

Drug-protein conjugates—XII a study of the disposition, irreversible binding and immunogenicity of penicillin in the rat

N.R. Kitteringham, G. Christie, J.W. Coleman, J.H.K. Yeung, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 928 KB

english, 1987

82

Drug-protein conjugates—XIV: Mechanisms of formation of protein-arylating intermediates from amodiaquine, a myelotoxin and hepatotoxin in man

J.L. Maggs, M.D. Tingle, N.R. Kitteringham, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 1.19 MB

english, 1988

83

Activation of mianserin and its metabolites by human liver microsomes

C. Lambert, B.K. Park, N.R. Kitteringham

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 723 KB

english, 1989

84

Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes

R.J. Riley, P. Roberts, N.R. Kitteringham, B.K. Park

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 934 KB

english, 1990

85

The mechanism of bioactivation and antigen formation of amodiaquine in the rat

Anthony C. Harrison, Neil R. Kitteringham, Janet B. Clarke, B.Kevin Park

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.07 MB

english, 1992

86

An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro

Munir Pirmohamed, Neil R. Kitteringham, Thomas M. Guenthner, Alasdair M. Breckenridge, B.Kevin Park

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 841 KB

english, 1992

87

The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes

Munir Pirmohamed, Neil R. Kitteringham, Alasdair M. Breckenridge, B.Kevin Park

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

88

An investigation of the formation of cytotoxic, genotoxic, protein-reactive and stable metabolites from naphthalene by human liver microsomes

Malcolm D. Tingle, Munir Pirmohamed, Elizabeth Templeton, Andrew S. Wilson, Stephen Madden, Neil R. Kitteringham, B.Kevin Park

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.18 MB

english, 1993

89

Kinetic parameters of lymphocyte microsomal epoxide hydrolase in carbamazepine hypersensitive patients: Assessment by radiometric HPLC

Carl D. Davis, Munir Pirmohamed, Neil R. Kitteringham, Rachel L. Allott, David Smith, B.Kevin Park

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 664 KB

english, 1995

90

Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity

Victoria J. Green, Munir Pirmohamed, Neil R. Kitteringham, Andrea Gaedigk, Denis M. Grant, Maureen Boxer, Brian Burchell, B.Kevin Park

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1007 KB

english, 1995

91

Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene

Neil R. Kitteringham, Luke Palmer, Andrew Owen, Lu-Yun Lian, Roz Jenkins, Sam Dowdall, Ian Gilmore, B. Kevin Park, Chris E. Goldring

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2007

Language:

english

File:

PDF, 637 KB

english, 2007

92

Microwave ablation of ex vivo human liver and colorectal liver metastases with a novel 14.5 GHz generator

Robert Jones, N. Kitteringham, S. Fenwick, G. Poston, P. Ghaneh, H. Malik

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

93

Information on the World Wide Web—how useful is it for parents?

Nurain Z. Sim, Lara Kitteringham, Lewis Spitz, Agostino Pierro, Edward Kiely, David Drake, Joe Curry

Journal:

Journal of Pediatric Surgery

Year:

2007

Language:

english

File:

PDF, 1.61 MB

english, 2007

94

Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway

Xiao-Ping Liu, Christopher E.P. Goldring, Ian M. Copple, Hai-Yi Wang, Wei Wei, Neil R. Kitteringham, B. Kevin Park

Journal:

Year:

2007

Language:

english

File:

PDF, 363 KB

english, 2007

95

Optimal dose identification: predicting a safe dose in man from animal studies

B.K. Park, N.R. Kitteringham, J.L. Maggs, D. Boocock, I. White, R. Elsby, M. Pirmohamed

Journal:

International Congress Series

Year:

2001

Language:

english

File:

PDF, 156 KB

english, 2001

96

2502 POSTER Microwave Ablation of Ex Vivo Human Liver and Colorectal Liver Metastases With a Novel 14.5 GHz Generator

R. Jones, D. Dunne, M. Terlizzo, S. Fenwick, H. Malik, G. Poston, N. Kitteringham, P. Ghaneh

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

97

Patterns of management of intussusception outside tertiary centres

Francis R. Calder, Susan Tan, Lara Kitteringham, Evelyn H. Dykes

Journal:

Journal of Pediatric Surgery

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

98

Protein binding of atenolol and propranolol to human serum albumin and in human plasma [proceedings]

HE Barber, GM Hawksworth, NR Kitteringham, J Petersen, JC Petrie, JM Swann

Journal:

British Journal of Clinical Pharmacology

Year:

1978

Language:

english

File:

PDF, 267 KB

english, 1978

99

Pharmacokinetic and pharmacodynamic interactions between phenprocoumon and atenolol or metoprolol.

H Spahn, W Kirch, E Mutschler, EE Ohnhaus, NR Kitteringham, HJ Logering, D Paar

Journal:

British Journal of Clinical Pharmacology

Year:

1984

Language:

english

File:

PDF, 525 KB

english, 1984

100

Interaction between the beta-adrenoceptor blockers metoprolol and atenolol with amitriptyline and their effects on oxidative liver metabolism.

W Kirch, H Spahn, NR Kitteringham, HJ Hutt, E Mutschler, EE Ohnhaus

Journal:

British Journal of Clinical Pharmacology

Year:

1984

Language:

english

File:

PDF, 512 KB

english, 1984