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51

Functional molecular imaging of ILK-mediated Akt/PKB signaling cascades and the associated role of -parvin

Kimura, M., Murakami, T., Kizaka-Kondoh, S., Itoh, M., Yamamoto, K., Hojo, Y., Takano, M., Kario, K., Shimada, K., Kobayashi, E.

Journal:

Journal of Cell Science

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

52

Identification of a Novel Thioredoxin-related Transmembrane Protein

Matsuo, Y., Akiyama, N., Nakamura, H., Yodoi, J., Noda, M., Kizaka-Kondoh, S.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 1.65 MB

english, 2001

53

Identification of a Series of Transforming Growth Factor beta -Responsive Genes by Retrovirus-Mediated Gene Trap Screening

Akiyama, N., Matsuo, Y., Sai, H., Noda, M., Kizaka-Kondoh, S.

Journal:

Molecular and Cellular Biology

Year:

2000

Language:

english

File:

PDF, 1.78 MB

english, 2000

54

Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element

Kageyama, Yukio, Sugiyama, Hiroshi, Ayame, Hirohito, Iwai, Aki, Fujii, Yasuhisa, Eric Huang, L., Kizaka-Kondoh, Shinae, Hiraoka, Masahiro, Kihara, Kazunori

Journal:

Acta Oncologica

Year:

2006

Language:

english

File:

PDF, 136 KB

english, 2006

55

Cyclic AMP Promotes cAMP-responsive Element-binding Protein-dependent Induction of Cellular Inhibitor of Apoptosis Protein-2 and Suppresses Apoptosis of Colon Cancer Cells through ERK1/2 and p38 MAPK

Nishihara, H., Hwang, M., Kizaka-Kondoh, S., Eckmann, L., Insel, P. A.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1019 KB

english, 2004

56

Induction of Hypoxia-inducible Factor 1 Activity by Muscarinic Acetylcholine Receptor Signaling

Hirota, K., Fukuda, R., Takabuchi, S., Kizaka-Kondoh, S., Adachi, T., Fukuda, K., Semenza, G. L.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 882 KB

english, 2004

57

Imaging of HIF-1-Active Tumor Hypoxia Using a Protein Effectively Delivered to and Specifically Stabilized in HIF-1-Active Tumor Cells

Kudo, T., Ueda, M., Kuge, Y., Mukai, T., Tanaka, S., Masutani, M., Kiyono, Y., Kizaka-Kondoh, S., Hiraoka, M., Saji, H.

Journal:

Journal of Nuclear Medicine

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

58

High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime

Kurokawa, Hiromi, Ito, Hidehiro, Inoue, Mai, Tabata, Kenji, Sato, Yoshifumi, Yamagata, Kazuya, Kizaka-Kondoh, Shinae, Kadonosono, Tetsuya, Yano, Shigenobu, Inoue, Masahiro, Kamachi, Toshiaki

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.16 MB

english, 2015

59

Selective Killing of Hypoxia-Inducible Factor-1-Active Cells Improves Survival in a Mouse Model of Invasive and Metastatic Pancreatic Cancer

Kizaka-Kondoh, S., Itasaka, S., Zeng, L., Tanaka, S., Zhao, T., Takahashi, Y., Shibuya, K., Hirota, K., Semenza, G. L., Hiraoka, M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 717 KB

english, 2009

60

Early Protective Effect of Bone Marrow Mononuclear Cells Against Ischemic White Matter Damage Through Augmentation of Cerebral Blood Flow

Y. Fujita, M. Ihara, T. Ushiki, H. Hirai, S. Kizaka-kondoh, M. Hiraoka, H. Ito, R. Takahashi

Year:

2010

Language:

english

File:

PDF, 992 KB

english, 2010

61

Thioredoxin-Binding Protein-2-Like Inducible Membrane Protein Is a Novel Vitamin D3 and Peroxisome Proliferator-Activated Receptor (PPAR)γ Ligand Target Protein that Regulates PPARγ Signaling

Oka, Shin-ichi, Masutani, Hiroshi, Liu, Wenrui, Horita, Hiroyuki, Wang, Dongmei, Kizaka-Kondoh, Shinae, Yodoi, Junji

Journal:

Year:

2006

Language:

english

File:

PDF, 768 KB

english, 2006

62

A metal carbonyl–protein needle composite designed for intracellular CO delivery to modulate NF-κB activity

Inaba, Hiroshi, Sanghamitra, Nusrat J. M., Fujita, Kenta, Sho, Takeya, Kuchimaru, Takahiro, Kitagawa, Susumu, Kizaka-Kondoh, Shinae, Ueno, Takafumi

Journal:

Molecular BioSystems

Year:

2015

Language:

english

File:

PDF, 2.10 MB

english, 2015

63

Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling

Kasuno, Kenji, Takabuchi, Satoshi, Fukuda, Kazuhiko, Kizaka-Kondoh, Shinae, Yodoi, Junji, Adachi, Takehiko, Semenza, Gregg L., Hirota, Kiichi

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1004 KB

english, 2004

64

Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model

Takanori Kitamura, Teruaki Fujishita, Pius Loetscher, Laszlo Revesz, Hiroki Hashida, Shinae Kizaka-Kondoh, Masahiro Aoki, Makoto M. Taketo and Webster K. Cavenee

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

65

Enhanced Percolation and Gene Expression in Tumor Hypoxia by PEGylated Polyplex Micelles

Han, Muri, Oba, Makoto, Nishiyama, Nobuhiro, Kano, Mitsunobu R, Kizaka-Kondoh, Shinae, Kataoka, Kazunori

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 770 KB

english, 2009

66

Targeting hypoxic cancer cells with a protein prodrug is effective in experimental malignant ascites

Inoue, Masahiro, Mukai, Mutsuko, Hamanaka, Yukou, Tatsuta, Masaharu, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae

Journal:

International Journal of Oncology

Year:

2004

Language:

english

File:

PDF, 2.43 MB

english, 2004

67

Transient over-expression of NGFI-A gene suppresses NGF-induced neurite outgrowth in PC12 cells

Matsumoto, Takako, Akiyama, Nobutake, Kizaka-Kondoh, Shinae, Noda, Makoto

Journal:

Year:

2000

Language:

english

File:

PDF, 1.89 MB

english, 2000

68

SPIE Proceedings [SPIE Biomedical Optics (BiOS) 2007 - San Jose, CA (Saturday 20 January 2007)] Genetically Engineered and Optical Probes for Biomedical Applications IV - Development of a novel fluorescent imaging probe for tumor hypoxia by use of a fusion protein with oxygen-dependent degradation domain of HIF-1α

Tanaka, Shotaro, Achilefu, Samuel, Bornhop, Darryl J., Kizaka-Kondoh, Shinae, Harada, Hiroshi, Raghavachari, Ramesh, Savitsky, Alexander P., Hiraoka, Masahiro, Wachter, Rebekka M.

Year:

2007

Language:

english

File:

PDF, 400 KB

english, 2007

69

Raf-1 protein kinase is an integral component of the oncogenic signal cascade shared by epidermal growth factor and platelet-derived growth factor.

Kizaka-Kondoh, S, Sato, K, Tamura, K, Nojima, H, Okayama, H

Journal:

Molecular and Cellular Biology

Year:

1992

Language:

english

File:

PDF, 2.44 MB

english, 1992

70

SPIE Proceedings [SPIE SPIE BiOS: Biomedical Optics - San Jose, CA (Saturday 24 January 2009)] Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications - Imaging probe for tumor malignancy

Tanaka, Shotaro, Achilefu, Samuel, Raghavachari, Ramesh, Kizaka-Kondoh, Shinae, Hiraoka, Hasahiro

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

71

n-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing systems

Kimura, Motohide, Takabuchi, Satoshi, Tanaka, Tomoharu, Murata, Miyahiko, Nishi, Kenichiro, Oda, Seiko, Oda, Tomoyuki, Kanai, Michiyuki, Fukuda, Kazuhiko, Kizaka-Kondoh, Shinae, Adachi, Takehiko, Taka

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 375 KB

english, 2008

72

Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model

Hoang, Ngoc Thi Hong, Kadonosono, Tetsuya, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae

Journal:

Year:

2016

Language:

english

File:

PDF, 1.60 MB

english, 2016

73

A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

Kuchimaru, Takahiro, Iwano, Satoshi, Kiyama, Masahiro, Mitsumata, Shun, Kadonosono, Tetsuya, Niwa, Haruki, Maki, Shojiro, Kizaka-Kondoh, Shinae

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

74

Domain architecture of vasohibins required for their chaperone-dependent unconventional extracellular release

Kadonosono, Tetsuya, Yimchuen, Wanaporn, Tsubaki, Takuya, Shiozawa, Tadashi, Suzuki, Yasuhiro, Kuchimaru, Takahiro, Sato, Yasufumi, Kizaka-Kondoh, Shinae

Journal:

Protein Science

Year:

2016

Language:

english

File:

PDF, 2.64 MB

english, 2016

75

Development of a Hypoxia-Selective Near-Infrared Fluorescent Probe for Non-invasive Tumor Imaging

Youssif, Bahaa Gamal Mohamed, Okuda, Kensuke, Kadonosono, Tetsuya, Salem, Ola Ibrahim Abdel Razek, Hayallah, Alaa Arafat Mohamed, Hussein, Mostafa Ahmed, Kizaka-Kondoh, Shinae, Nagasawa, Hideko

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

76

Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery: Hypoxia-Inducible Factor-1 (HIF-1)-Active Cells as a Target for Cancer Therapy

Kizaka-Kondoh, Shinae, Kuchimaru, Takahiro, Kadonosono, Tetsuya

Journal:

Journal of Pharmacological Sciences

Year:

2011

Language:

english

File:

PDF, 544 KB

english, 2011

77

10.1538/expanim1992.23.43

KIZAKA-KONDOH, Shinae, HIRAOKA, Masahiro

Journal:

Proceedings of The Japanese Society of Animal Models for Human Diseases

Year:

2007

Language:

english

File:

PDF, 7.00 MB

english, 2007

78

The effect of triamcinolone acetonide on laser-induced choroidal neovascularization in mice using a hypoxia visualization bio-imaging probe

Takata, Shinsuke, Masuda, Tomomi, Nakamura, Shinsuke, Kuchimaru, Takahiro, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Nagasawa, Hideko, kizaka-Kondoh, Shinae, Hara, Hideaki

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

79

A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system

Kuchimaru, Takahiro, Suka, Tomoya, Hirota, Keisuke, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

80

10.1271/kagakutoseibutsu1962.45.779

KANZAKI, Tatsuya, MAKINO, Akira, KIMURA, Shunsaku, KIZAKA-KONDOH, Shinae, HIRAOKA, Masahiro, OZEKI, Ei-ichi

Journal:

KAGAKU TO SEIBUTSU

Year:

2007

File:

PDF, 12.74 MB

2007

81

Noninvasive Tracking of Donor Cell Homing by Near-Infrared Fluorescence Imaging Shortly after Bone Marrow Transplantation

Ushiki, Takashi, Kizaka-Kondoh, Shinae, Ashihara, Eishi, Tanaka, Shotaro, Masuko, Masayoshi, Hirai, Hideyo, Kimura, Shinya, Aizawa, Yoshifusa, Maekawa, Taira, Hiraoka, Masahiro, Rappoport, Joshua Z.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

82

In Vivo Imaging of HIF-Active Tumors by an Oxygen-Dependent Degradation Protein Probe with an Interchangeable Labeling System

Kuchimaru, Takahiro, Kadonosono, Tetsuya, Tanaka, Shotaro, Ushiki, Takashi, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae, Shioda, Toshi

Journal:

Year:

2010

Language:

english

File:

PDF, 4.17 MB

english, 2010

83

In Vivo Imaging of Brain Ischemia Using an Oxygen-Dependent Degradative Fusion Protein Probe

Fujita, Youshi, Kuchimaru, Takahiro, Kadonosono, Tetsuya, Tanaka, Shotaro, Hase, Yoshiki, Tomimoto, Hidekazu, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae, Ihara, Masafumi, Takahashi, Ryosuke, Deli, Maria

Journal:

Year:

2012

Language:

english

File:

PDF, 2.49 MB

english, 2012

84

A Fluorescent Protein Scaffold for Presenting Structurally Constrained Peptides Provides an Effective Screening System to Identify High Affinity Target-Binding Peptides

Kadonosono, Tetsuya, Yabe, Etsuri, Furuta, Tadaomi, Yamano, Akihiro, Tsubaki, Takuya, Sekine, Takuya, Kuchimaru, Takahiro, Sakurai, Minoru, Kizaka-Kondoh, Shinae, Mason, Jody Michael

Journal:

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

85

A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries

Kuchimaru, Takahiro, Kataoka, Naoya, Nakagawa, Kenji, Isozaki, Tatsuhiro, Miyabara, Hitomi, Minegishi, Misa, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

86

Novel lymphoid enhancer-binding factor 1-cytoglobin axis promotes extravasation of osteosarcoma cells into the lungs

Pongsuchart, Mongkol, Kuchimaru, Takahiro, Yonezawa, Sakiko, Tran, Diem Thi Phuong, Kha, Nguyen The, Hoang, Ngoc Thi Hong, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae

Journal:

Year:

2018

Language:

english

File:

PDF, 2.35 MB

english, 2018

87

Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells

Iizuka-Ohashi, Mahiro, Watanabe, Motoki, Sukeno, Mamiko, Morita, Mie, Hoang, Ngoc Thi Hong, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae, Sowa, Yoshihiro, Sakaguchi, Koichi, Taguchi, Tetsuya, Sakai, Tos

Journal:

Year:

2018

Language:

english

File:

PDF, 2.70 MB

english, 2018

88

Synthesis and luminescence properties of near-infrared N -heterocyclic luciferin analogues for in vivo optical imaging

Saito, Ryohei, Kuchimaru, Takahiro, Higashi, Shoko, Lu, Shijia W., Kiyama, Masahiro, Iwano, Satoshi, Obata, Rika, Hirano, Takashi, Kizaka-Kondoh, Shinae, Maki, Shojiro A.

Journal:

Bulletin of the Chemical Society of Japan

Year:

2018

Language:

english

File:

PDF, 733 KB

english, 2018

89

CrkII signals from epidermal growth factor receptor to Ras.

Kizaka-Kondoh, S., Matsuda, M., Okayama, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.93 MB

english, 1996

90

Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity

Fuse, Shinichiro, Suzuki, Kensuke, Kuchimaru, Takahiro, Kadonosono, Tetsuya, Ueda, Hiroki, Sato, Shinichi, Kizaka-Kondoh, Shinae, Nakamura, Hiroyuki

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 858 KB

english, 2019

91

Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use

Kadonosono, Tetsuya, Yimchuen, Wanaporn, Ota, Yumi, See, Kyra, Furuta, Tadaomi, Shiozawa, Tadashi, Kitazawa, Maika, Goto, Yu, Patil, Akash, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.56 MB

2020

92

Strategic design to create HER2-targeting proteins with target-binding peptides immobilized on a fibronectin type III domain scaffold

Yimchuen, Wanaporn, Kadonosono, Tetsuya, Ota, Yumi, Sato, Shinichi, Kitazawa, Maika, Shiozawa, Tadashi, Kuchimaru, Takahiro, Taki, Masumi, Ito, Yuji, Nakamura, Hiroyuki, Kizaka-Kondoh, Shinae

Journal:

Year:

2020

File:

PDF, 1.50 MB

2020