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51

Mechanisms of Osteocyte Mechanotransduction

Astrid D. Bakker, Jenneke Klein-Nulend

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2010

Language:

english

File:

PDF, 240 KB

english, 2010

52

Mechanosensing in Bone

Jenneke Klein-Nulend

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2010

Language:

english

File:

PDF, 69 KB

english, 2010

53

Dynamic shear stress in parallel-plate flow chambers

Rommel G. Bacabac, Theo H. Smit, Stephen C. Cowin, Jack J.W.A. Van Loon, Frans T.M. Nieuwstadt, Rob Heethaar, Jenneke Klein-Nulend

Journal:

Journal of Biomechanics

Year:

2005

Language:

english

File:

PDF, 400 KB

english, 2005

54

Extracellular NO signalling from a mechanically stimulated osteocyte

Aviral Vatsa, Theo H. Smit, Jenneke Klein-Nulend

Journal:

Journal of Biomechanics

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

55

Round versus flat: Bone cell morphology, elasticity, and mechanosensing

Rommel G. Bacabac, Daisuke Mizuno, Christoph F. Schmidt, Fred C. MacKintosh, Jack J.W.A. Van Loon, Jenneke Klein-Nulend, Theo H. Smit

Journal:

Journal of Biomechanics

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

56

“The Production of Nitric Oxide and Prostaglandin E2 by Primary Bone Cells is Shear Stress Dependent” by Bakker et al.

A.D. Bakker, K. Soejima, J. Klein-Nulend, E.H. Burger

Journal:

Journal of Biomechanics

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

57

Low-intensity ultrasound stimulates endochondral ossification in vitro

P.A Nolte, J Klein-Nulend, G.H.R Albers, R.K Marti, C.M Semeins, S.W Goei, E.H Burger

Journal:

Journal of Orthopaedic Research

Year:

2001

Language:

english

File:

PDF, 847 KB

english, 2001

58

Mechanosensitivity of dental pulp stem cells is related to their osteogenic maturity

David C. E. Kraft, Dorthe A. Bindslev, Birte Melsen, Basem M. Abdallah, Moustapha Kassem, Jenneke Klein-Nulend

Journal:

European Journal of Oral Sciences

Year:

2010

Language:

english

File:

PDF, 468 KB

english, 2010

59

Bio Imaging of Intracellular NO Production in Single Bone Cells After Mechanical Stimulation

Aviral Vatsa, Daisuke Mizuno, Theo H Smit, Christoph F Schmidt, Fred C MacKintosh, Jenneke Klein-Nulend

Journal:

Journal of Bone and Mineral Research

Year:

2006

Language:

english

File:

PDF, 2.70 MB

english, 2006

60

Pulsating Fluid Flow Stimulates Prostaglandin Release and Inducible Prostaglandin G/H Synthase mRNA Expression in Primary Mouse Bone Cells

Jenneke Klein-Nulend, Elisabeth H. Burger, Cornelis M. Semeins, Lawrence G. Raisz, Carol C. Pilbeam

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 454 KB

english, 1997

61

Polyamines Modulate Nitric Oxide Production and Cox-2 Gene Expression in Response to Mechanical Loading in Human Adipose Tissue-Derived Mesenchymal Stem Cells

Geuranne S. Tjabringa, Peter S. Vezeridis, Behrouz Zandieh-Doulabi, Marco N. Helder, Paul I.J.M. Wuisman, Jenneke Klein-Nulend

Journal:

Year:

2006

Language:

english

File:

PDF, 281 KB

english, 2006

62

Effect of 1,25-dihydroxyvitamin D3 on prostaglandin E2 production in cultured mouse parietal bones

Jenneke Klein-Nulend, Carol C. Pilbeam, Dr. Lawrence G. Raisz

Journal:

Journal of Bone and Mineral Research

Year:

1991

Language:

english

File:

PDF, 482 KB

english, 1991

63

Bone cells from patients with quiescent Crohn's disease show a reduced growth potential and an impeded maturation

Angela E. Oostlander, Nathalie Bravenboer, Huib W. van Essen, Jenneke Klein-Nulend, Willem F. Lems, Bert A.J.M. Schulten, Gerard Dijkstra, C. Janneke van der Woude, Ad A. van Bodegraven, Paul Lips, on

Journal:

Journal of Cellular Biochemistry

Year:

2012

Language:

english

File:

PDF, 206 KB

english, 2012

64

Effect of mechanical stimulation on the production of soluble bone factors in cultured fetal mouse calvariae

Jenneke Klein-Nulend, Cornelis M. Semeins, J. Paul Veldhuijzen, Elisabeth H. Burger

Journal:

Cell and Tissue Research

Year:

1993

Language:

english

File:

PDF, 535 KB

english, 1993

65

The polymine spermine regulates osteogenic differentiation in adipose stem cells

G.S. Tjabringa, B. Zandieh-Doulabi, M.N. Helder, M. Knippenberg, P.I.J.M. Wuisman, J. Klein-Nulend

Journal:

Journal of Cellular and Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

66

Human Maxillary Sinus Floor Elevation as a Model for Bone Regeneration Enabling the Application of One-Step Surgical Procedures

Farré-Guasch, Elisabet, Prins, Henk-Jan, Overman, Janice R., ten Bruggenkate, Christiaan M., Schulten, Engelbert A.J.M., Helder, Marco N., Klein-Nulend, Jenneke

Journal:

Tissue Engineering Part B Reviews

Year:

2013

Language:

english

File:

PDF, 645 KB

english, 2013

67

Pulsating Fluid Flow Increases Prostaglandin Production by Cultured Chicken Osteocytes—A Cytoskeleton-Dependent Process

N.E. Ajubi, J. Klein-Nulend, P.J. Nijweide, T. Vrijheid-Lammers, M.J. Alblas, E.H. Burger

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 103 KB

english, 1996

68

Nitric Oxide Response to Shear Stress by Human Bone Cell Cultures Is Endothelial Nitric Oxide Synthase Dependent

J. Klein-Nulend, M.H. Helfrich, J.G.H. Sterck, H. MacPherson, M. Joldersma, S.H. Ralston, C.M. Semeins, E.H. Burger

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 959 KB

english, 1998

69

Differential Stimulation of Prostaglandin G/H Synthase-2 in Osteocytes and Other Osteogenic Cells by Pulsating Fluid Flow

I. Westbroek, N.E. Ajubi, M.J. Alblas, C.M. Semeins, J. Klein-Nulend, E.H. Burger, P.J. Nijweide

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 71 KB

english, 2000

70

Osteopontin-Deficient Bone Cells Are Defective in Their Ability to Produce NO in Response to Pulsatile Fluid Flow

D.T. Denhardt, E.H. Burger, C. Kazanecki, S. Krishna, C.M. Semeins, J. Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 76 KB

english, 2001

71

Inhibition by 17β-estradiol of PTH stimulated resorption and prostaglandin production in cultured neonatal mouse calvariae

Carol C. Pilbeam, Jenneke Klein-Nulend, Lawrence G. Raisz

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 425 KB

english, 1989

72

Nitric oxide production by bone cells is fluid shear stress rate dependent

Rommel G Bacabac, Theo H Smit, Margriet G Mullender, Saskia J Dijcks, Jack J.W.A Van Loon, Jenneke Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 253 KB

english, 2004

73

Shear stress inhibits while disuse promotes osteocyte apoptosis

Astrid Bakker, Jenneke Klein-Nulend, Elisabeth Burger

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

74

The effect of cytoskeletal disruption on pulsatile fluid flow-induced nitric oxide and prostaglandin E2 release in osteocytes and osteoblasts

James G. McGarry, Jenneke Klein-Nulend, Patrick J. Prendergast

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 836 KB

english, 2005

75

Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation

Peter S. Vezeridis, Cornelis M. Semeins, Qian Chen, Jenneke Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

76

Paxillin localisation in osteocytes—Is it determined by the direction of loading?

A. Vatsa, C.M. Semeins, T.H. Smit, J. Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 303 KB

english, 2008

77

Inhibition of osteocyte apoptosis by fluid flow is mediated by nitric oxide

S.D. Tan, A.D. Bakker, C.M. Semeins, A.M. Kuijpers-Jagtman, J. Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

78

Early activation of the β-catenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase

Ana Santos, Astrid D. Bakker, Behrouz Zandieh-Doulabi, Jolanda M.A. de Blieck-Hogervorst, Jenneke Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 472 KB

english, 2010

79

MT1-MMP modulates the mechanosensitivity of osteocytes

Rishikesh N. Kulkarni, Astrid D. Bakker, Elisabeth V. Gruber, Thomas D. Chae, Joris B.B. Veldkamp, Jenneke Klein-Nulend, Vincent Everts

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 639 KB

english, 2012

80

Mechanical loading prevents the stimulating effect of IL-1β on osteocyte-modulated osteoclastogenesis

Rishikesh N. Kulkarni, Astrid D. Bakker, Vincent Everts, Jenneke Klein-Nulend

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 547 KB

english, 2012

81

Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption

S. Djien Tan, Teun J. de Vries, Anne Marie Kuijpers-Jagtman, Cornelis M. Semeins, Vincent Everts, Jenneke Klein-Nulend

Journal:

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

82

Nitric oxide synthesis in eNOS null mice in response to fluid shear stress: A slow story

Carmen Huesa, Astrid Bakker, Jenneke Klein-Nulend, Richard M. Aspden, Miep H. Helfrich

Journal:

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

83

Osteocyte morphology in fibula and calvaria — Is there a role for mechanosensing?

Aviral Vatsa, Roel G. Breuls, Cornelis M. Semeins, Philip L. Salmon, Theo H. Smit, Jenneke Klein-Nulend

Journal:

Year:

2008

Language:

english

File:

PDF, 789 KB

english, 2008

84

Low-intensity pulsed ultrasound increases bone volume, osteoid thickness and mineral apposition rate in the area of fracture healing in patients with a delayed union of the osteotomized fibula

Sjoerd Rutten, Peter A. Nolte, Clara M. Korstjens, Marion A. van Duin, Jenneke Klein-Nulend

Journal:

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

85

Predictive value of femoral head heterogeneity for fracture risk

E. Tanck, A.D. Bakker, S. Kregting, B. Cornelissen, J. Klein-Nulend, B. Van Rietbergen

Journal:

Year:

2009

Language:

english

File:

PDF, 815 KB

english, 2009

86

Canonical and non-canonical Wnts affect osteogenic differentiation of primary human adipose tissue-derived mesenchymal stem cells

A. Santos⁎, A.D. Bakker, J.M.A. de Blieck-Hogervorst, J. Klein-Nulend

Journal:

Year:

2009

Language:

english

File:

PDF, 90 KB

english, 2009

87

Effect of inflammatory cytokines on the differentiation of primary human bone cells in patients with crohn's disease

A.E. Oostlander, N. Bravenboer, J. Klein-Nulend, W.F. Lems, E.A. Schulten, A.A. van Bodegraven, P. Lips

Journal:

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

88

1,25-Dihydroxyvitamin D3 affects pulsating fluid flow-induced nitric oxide production by osteoblasts dependent on the vdr pathway activated

H.M.E. Willems, A.D. Bakker, E.G.H. Van den Heuvel, J. Klein-Nulend

Journal:

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

89

Mechanical loading affects osteoclastogenesis-related gene expression in osteocytes

R.N. Kulkarni⁎, A.D. Bakker, V. Everts, J. Klein-Nulend

Journal:

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

90

Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density — Is there a role for mechanosensing?

Ruud P. van Hove, Peter A. Nolte, Aviral Vatsa, Cornelis M. Semeins, Philip L. Salmon, Theo H. Smit, Jenneke Klein-Nulend

Journal:

Year:

2009

Language:

english

File:

PDF, 548 KB

english, 2009

91

Strontium ranelate positively affects the response of osteocytes to mechanical loading and osteocyte signalling towards osteoclasts

A.D. Bakker, B. Zandieh-Doulabi, J. Klein-Nulend

Journal:

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

92

Osteocytes produce factors involved in the adaptive response of muscle to mechanical loading

P. Juffer, R.T. Jaspers, P. Lips, A.D. Bakker, J. Klein-Nulend

Journal:

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

93

MT1-MMP affects the mechanosensitivity of osteocytes

R.N. Kulkarni, A.D. Bakker, E.V. Gruber, T.D. Chae, J.B.B. Veldkamp, V. Everts, J. Klein-Nulend

Journal:

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

94

NO signaling in mechanical adaptation of bone

J. Klein-Nulend⁎, R.G. Bacabac, A. Vatsa, C.M. Semeins, A.D. Bakker

Journal:

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

95

C2C12 myotubes produce soluble factors affecting osteoclast formation

P. Juffer⁎, R.T. Jaspers, P. Lips, A.D. Bakker, J. Klein-Nulend

Journal:

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

96

Mechanical loading of osteocytes inhibits IL-1Β-induced osteoclastogenesis

R.N. Kulkarni⁎, A.D. Bakker, V. Everts, J. Klein-Nulend

Journal:

Year:

2012

Language:

english

File:

PDF, 94 KB

english, 2012

97

Mechanobiology of bone tissue

J. Klein-Nulend, R.G. Bacabac, M.G. Mullender

Journal:

Pathologie Biologie

Year:

2005

File:

PDF, 254 KB

2005

98

VDR dependent and independent effects of 1,25-dihydroxyvitamin D3 on nitric oxide production by osteoblasts

Hubertine M.E. Willems, Ellen G.H.M. van den Heuvel, Geert Carmeliet, Anne Schaafsma, Jenneke Klein-Nulend, Astrid D. Bakker

Journal:

Year:

2012

Language:

english

File:

PDF, 614 KB

english, 2012

99

Mechanotransduction in bone cells proceeds via activation of COX-2, but not COX-1

A.D. Bakker, J. Klein-Nulend, E.H. Burger

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 142 KB

english, 2003

100

Microgravity and Bone Cell Mechanosensitivity

E.H Burger, J Klein-Nulend

Journal:

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998

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