Knowles, Tuomas P J: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

51

Characterisation of Amyloid Fibril Formation by Small Heat-shock Chaperone Proteins Human αA-, αB- and R120G αB-Crystallins

Sarah Meehan, Tuomas P.J. Knowles, Andrew J. Baldwin, Jeffrey F. Smith, Adam M. Squires, Phillip Clements, Teresa M. Treweek, Heath Ecroyd, Gian Gaetano Tartaglia, Michele Vendruscolo, Cait E. MacPhee

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.68 MB

english, 2007

52

Imaging Amyloid Fibrils within Cells Using a Se-Labelling Strategy

Alexandra E. Porter, Tuomas P.J. Knowles, Karin Muller, Sarah Meehan, Eva McGuire, Jeremy Skepper, Mark E. Welland, Christopher M. Dobson

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

53

Conserved C-Terminal Charge Exerts a Profound Influence on the Aggregation Rate of α-Synuclein

Katerina Levitan, David Chereau, Samuel I.A. Cohen, Tuomas P.J. Knowles, Christopher M. Dobson, Anthony L. Fink, John P. Anderson, Jason M. Goldstein, Glenn L. Millhauser

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 712 KB

english, 2011

54

From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

Samuel I.A. Cohen, Michele Vendruscolo, Christopher M. Dobson, Tuomas P.J. Knowles

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 667 KB

english, 2012

55

Role of Elongation and Secondary Pathways in S6 Amyloid Fibril Growth

Lorenzen, Nikolai, Cohen, Samuel I.A., Nielsen, Søren B., Herling, Therese W., Christiansen, Gunna, Dobson, Christopher M., Knowles, Tuomas P.J., Otzen, Daniel

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 489 KB

english, 2012

56

Probing small molecule binding to amyloid fibrils

Buell, Alexander K., Esbjörner, Elin K., Riss, Patrick J., White, Duncan A., Aigbirhio, Franklin I., Toth, Gergely, Welland, Mark E., Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

Physical Chemistry Chemical Physics

Year:

2011

Language:

english

File:

PDF, 3.91 MB

english, 2011

57

The Interaction of αB-Crystallin with Mature α-Synuclein Amyloid Fibrils Inhibits Their Elongation

Waudby, Christopher A., Knowles, Tuomas P.J., Devlin, Glyn L., Skepper, Jeremy N., Ecroyd, Heath, Carver, John A., Welland, Mark E., Christodoulou, John, Dobson, Christopher M., Meehan, Sarah

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 726 KB

english, 2010

58

Interactions between Amyloidophilic Dyes and Their Relevance to Studies of Amyloid Inhibitors

Buell, Alexander K., Dobson, Christopher M., Knowles, Tuomas P.J., Welland, Mark E.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 690 KB

english, 2010

59

Perturbation of the Stability of Amyloid Fibrils through Alteration of Electrostatic Interactions

Shammas, Sarah L., Knowles, Tuomas P.J., Baldwin, Andrew J., MacPhee, Cait E., Welland, Mark E., Dobson, Christopher M., Devlin, Glyn L.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 613 KB

english, 2011

60

Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation

Shammas, Sarah L., Waudby, Christopher A., Wang, Shuyu, Buell, Alexander K., Knowles, Tuomas P.J., Ecroyd, Heath, Welland, Mark E., Carver, John A., Dobson, Christopher M., Meehan, Sarah

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 886 KB

english, 2011

61

Enhanced Stability of Human Prion Proteins with Two Disulfide Bridges

Knowles, Tuomas P.J., Zahn, Ralph

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 167 KB

english, 2006

62

Electrostatic Effects in Filamentous Protein Aggregation

Buell, Alexander K., Hung, Peter, Salvatella, Xavier, Welland, Mark E., Dobson, Christopher M., Knowles, Tuomas P.J.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 805 KB

english, 2013

63

Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations

Cohen, Samuel I. A., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

The Journal of Chemical Physics

Year:

2011

Language:

english

File:

PDF, 934 KB

english, 2011

64

Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 793 KB

english, 2013

65

Protein Aggregation in Crowded Environments

White, Duncan A., Buell, Alexander K., Knowles, Tuomas P. J., Welland, Mark E., Dobson, Christopher M.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 2.81 MB

english, 2010

66

Metastability of Native Proteins and the Phenomenon of Amyloid Formation

Baldwin, Andrew J., Knowles, Tuomas P. J., Tartaglia, Gian Gaetano, Fitzpatrick, Anthony W., Devlin, Glyn L., Shammas, Sarah Lucy, Waudby, Christopher A., Mossuto, Maria F., Meehan, Sarah, Gras, Sally

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

67

Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay

Arosio, Paolo, Cukalevski, Risto, Frohm, Birgitta, Knowles, Tuomas P. J., Linse, Sara

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

68

Expanding the Solvent Chemical Space for Self-Assembly of Dipeptide Nanostructures

Mason, Thomas O., Chirgadze, Dimitri Y., Levin, Aviad, Adler-Abramovich, Lihi, Gazit, Ehud, Knowles, Tuomas P. J., Buell, Alexander K.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.16 MB

english, 2014

69

Insights into the Inhibition Mechanism of Biomolecular Self-Assembly from Chemical Kinetics

Arosio, Paolo, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P.J.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

70

Amyloid β-Protein: The Influence of Intrinsic and Extrinsic Factors on Fibril Formation

Cukalevski, Risto, Yang, Xiaoting, Cohen, Samuel, Boland, Barry, Frohm, Birgitta, Thulin, Eva, Walsh, Dominic, Knowles, Tuomas, Linse, Sara

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 155 KB

english, 2014

71

Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering

Dubnovitsky, Anatoly, Sandberg, Anders, Luheshi, Leila, Söllvander, Sofia, de Barros, Teresa Pereira, Macao, Bertil, Knowles, Tuomas, Biverstål, Henrik, Lendel, Christofer, Ekholm-Petterson, Frida, La

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

72

Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation

Aprile, Francesco A., Meisl, Georg, Buell, Alexander K., Flagmeier, Patrick, Dobson, Christopher M., Vendruscolo, Michele, Knowles, Tuomas P.J.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 115 KB

english, 2014

73

Nanoscale spatially resolved infrared spectra from single microdroplets

Müller, Thomas, Ruggeri, Francesco Simone, Kulik, Andrzej J., Shimanovich, Ulyana, Mason, Thomas O., Knowles, Tuomas P. J., Dietler, Giovanni

Journal:

Year:

2014

Language:

english

File:

PDF, 1.91 MB

english, 2014

74

Density-Gradient-Free Microfluidic Centrifugation for Analytical and Preparative Separation of Nanoparticles

Arosio, Paolo, Müller, Thomas, Mahadevan, L., Knowles, Tuomas P. J.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.70 MB

english, 2014

75

Quantitative Analysis of Diffusive Reactions at the Solid–Liquid Interface in Finite Systems

Michaels, Thomas C. T., Buell, Alexander K., Terentjev, Eugene M., Knowles, Tuomas P. J.

Journal:

The Journal of Physical Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

76

Single Point Mutations Induce a Switch in the Molecular Mechanism of the Aggregation of the Alzheimer’s Disease Associated Aβ 42 Peptide

Bolognesi, Benedetta, Cohen, Samuel I. A., Aran Terol, Pablo, Esbjörner, Elin K., Giorgetti, Sofia, Mossuto, Maria F., Natalello, Antonino, Brorsson, Ann-Christin, Knowles, Tuomas P. J., Dobson, Chris

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

77

Selenium-Enhanced Electron Microscopic Imaging of Different Aggregate Forms of a Segment of the Amyloid β Peptide in Cells

McGuire, Eva K., Motskin, Michael, Bolognesi, Benedetta, Bergin, Shane D., Knowles, Tuomas P. J., Skepper, Jeremy, Luheshi, Leila M., McComb, David W., Dobson, Christopher M., Porter, Alexandra E.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.56 MB

english, 2012

78

A Clear View of Polymorphism, Twist, and Chirality in Amyloid Fibril Formation

Volpatti, Lisa R., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.34 MB

english, 2013

79

Analysis of structural order in amyloid fibrils

Knowles, Tuomas P J, Smith, Jeffrey F, Devlin, Glyn L, Dobson, Christopher M, Welland, Mark E

Journal:

Year:

2007

Language:

english

File:

PDF, 263 KB

english, 2007

80

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein

Kelly, Sadie E., Meisl, Georg, Rowling, Pamela J. E., McLaughlin, Stephen H., Knowles, Tuomas, Itzhaki, Laura S.

Journal:

Physical Chemistry Chemical Physics

Year:

2014

Language:

english

File:

PDF, 3.40 MB

english, 2014

81

Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

Levin, Aviad, Mason, Thomas O., Adler-Abramovich, Lihi, Buell, Alexander K., Meisl, George, Galvagnion, Celine, Bram, Yaron, Stratford, Samuel A., Dobson, Christopher M., Knowles, Tuomas P. J., Gazit,

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

82

Polymer physics inspired approaches for the study of the mechanical properties of amyloid fibrils

Volpatti, Lisa R., Knowles, Tuomas P. J.

Journal:

Journal of Polymer Science Part B: Polymer Physics

Year:

2014

Language:

english

File:

PDF, 545 KB

english, 2014

83

Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization

Michaels, Thomas C. T., Knowles, Tuomas P. J.

Journal:

The Journal of Chemical Physics

Year:

2014

Language:

english

File:

PDF, 796 KB

english, 2014

84

Self-Assembly of Amyloid Fibrils That Display Active Enzymes

Zhou, Xiao-Ming, Entwistle, Aiman, Zhang, Hong, Jackson, Antony P., Mason, Thomas O., Shimanovich, Ulyana, Knowles, Tuomas P. J., Smith, Andrew T., Sawyer, Elizabeth B., Perrett, Sarah

Journal:

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

85

Asymptotic solutions of the Oosawa model for the length distribution of biofilaments

Michaels, Thomas C. T., Garcia, Gonzalo A., Knowles, Tuomas P. J.

Journal:

The Journal of Chemical Physics

Year:

2014

Language:

english

File:

PDF, 2.11 MB

english, 2014

86

Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations

Cohen, Samuel I. A., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.

Journal:

The Journal of Chemical Physics

Year:

2011

Language:

english

File:

PDF, 747 KB

english, 2011

87

Kinetic theory of protein filament growth: Self-consistent methods and perturbative techniques

Michaels, Thomas C. T., Knowles, Tuomas P. J.

Journal:

International Journal of Modern Physics B

Year:

2015

Language:

english

File:

PDF, 650 KB

english, 2015

88

Label-free detection of amyloid growth with microcantilever sensors

Knowles, Tuomas P J, Shu, Wenmiao, Huber, François, Lang, Hans Peter, Gerber, Christoph, Dobson, Christopher M, Welland, Mark E

Journal:

Year:

2008

Language:

english

File:

PDF, 631 KB

english, 2008

89

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

Galvagnion, Céline, Buell, Alexander K, Meisl, Georg, Michaels, Thomas C T, Vendruscolo, Michele, Knowles, Tuomas P J, Dobson, Christopher M

Journal:

Nature Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

90

Tetracycline Nanoparticles as Antibacterial and Gene-Silencing Agents

Shimanovich, Ulyana, Lipovsky, Anat, Eliaz, Dror, Zigdon, Sally, Knowles, Tuomas P. J., Nitzan, Yeshayahu, Michaeli, Shulamit, Gedanken, Aharon

Journal:

Advanced Healthcare Materials

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

91

On the lag phase in amyloid fibril formation

Arosio, Paolo, Knowles, Tuomas P. J., Linse, Sara

Journal:

Physical Chemistry Chemical Physics

Year:

2015

Language:

english

File:

PDF, 2.81 MB

english, 2015

92

Quantitative approaches for characterising fibrillar protein nanostructures

Knowles, Tuomas P. J., White, Duncan A., Dobson, Christopher M., Welland, Mark E.

Journal:

MRS Proceedings

Year:

2010

Language:

english

File:

PDF, 754 KB

english, 2010

93

Preventing peptide and protein misbehavior: Fig. 1.

Arosio, Paolo, Meisl, Georg, Andreasen, Maria, Knowles, Tuomas P. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 718 KB

english, 2015

94

SPIE Proceedings [SPIE SPIE BiOS - San Francisco, California, United States (Saturday 1 February 2014)] Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XII - Quantitative sensing of microviscosity in protocells and amyloid materials using fluorescence lifetime imaging of molecular rotors

Farkas, Daniel L., Nicolau, Dan V., Leif, Robert C., Thompson, Alex J., Tang, T.-Y. Dora, Herling, Therese W., Che Hak, C. Rohaida, Mann, Stephen, Knowles, Tuomas P. J., Kuimova, Marina K.

Year:

2014

Language:

english

File:

PDF, 3.85 MB

english, 2014

95

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

Shammas, Sarah L., Garcia, Gonzalo A., Kumar, Satish, Kjaergaard, Magnus, Horrocks, Mathew H., Shivji, Nadia, Mandelkow, Eva, Knowles, Tuomas P.J., Mandelkow, Eckhard, Klenerman, David

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

96

Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase

Pica, Andrea, Merlino, Antonello, Buell, Alexander K., Knowles, Tuomas P. J., Pizzo, Elio, D'Alessio, Giuseppe, Sica, Filomena, Mazzarella, Lelio

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

97

Enzymatically Active Microgels from Self-Assembling Protein Nanofibrils for Microflow Chemistry

Zhou, Xiao-Ming, Shimanovich, Ulyana, Herling, Therese W., Wu, Si, Dobson, Christopher M., Knowles, Tuomas P. J., Perrett, Sarah

Journal:

Year:

2015

Language:

english

File:

PDF, 6.52 MB

english, 2015

98

Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation

Fitzpatrick, Anthony W., Knowles, Tuomas P. J., Waudby, Christopher A., Vendruscolo, Michele, Dobson, Christopher M., Pande, Vijay S.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 350 KB

english, 2011

99

Molecular Rotors Provide Insights into Microscopic Structural Changes During Protein Aggregation

Thompson, Alexander J., Herling, Therese W., Kubánková, Markéta, Vyšniauskas, Aurimas, Knowles, Tuomas P. J., Kuimova, Marina K.

Journal:

Journal of Physical Chemistry B

Year:

2015

Language:

english

File:

PDF, 3.25 MB

english, 2015

100

Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of alpha-synuclein oligomers

Horrocks, Mathew Harry, Tosatto, Laura, Dear, Alexander J, Garcia, Gonzalo Andres, Iljina, Marija, Cremades, Nunilo, Dalla Serra, Mauro, Knowles, Tuomas P.J., Dobson, Christopher M., Klenerman, David

Journal:

Analytical Chemistry

Year:

2015

Language:

english

File:

PDF, 6.66 MB

english, 2015