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51

yDNA: A New Geometry for Size-Expanded Base Pairs

Haige Lu, Kaizhang He, Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 181 KB

english, 2004

52

Assembly of the Complete Eight-Base Artificial Genetic Helix, xDNA, and Its Interaction with the Natural Genetic System

Jianmin Gao, Haibo Liu, Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 415 KB

english, 2005

53

Remarkable Sensitivity to DNA Base Shape in the DNA Polymerase Active Site

Herman O. Sintim, Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 404 KB

english, 2006

54

The Roles of Hydrogen Bonding and Sterics in RNA Interference

Alvaro Somoza, Jijumon Chelliserrykattil, Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 237 KB

english, 2006

55

Efficient Replication Bypass of Size-Expanded DNA Base Pairs in Bacterial Cells

James C. Delaney, Jianmin Gao, Haibo Liu, Nidhi Shrivastav, John M. Essigmann, Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 353 KB

english, 2009

56

Polyfluorophores on a DNA Backbone: Sensors of Small Molecules in the Vapor Phase

Dr. Florent Samain, Dr. Samantak Ghosh, Yin Nah Teo, Prof. Dr. Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 452 KB

english, 2010

57

Protease Probes Built from DNA: Multispectral Fluorescent DNA–Peptide Conjugates as Caspase Chemosensors

Nan Dai, Jia Guo, Yin Nah Teo, Prof. Dr. Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 516 KB

english, 2011

58

Direct Fluorescence Monitoring of DNA Base Excision Repair

Dr. Toshikazu Ono, Dr. Shenliang Wang, Dr. Chi-Kin Koo, Lisa Engstrom, Prof. Dr. Sheila S. David, Prof. Dr. Eric T. Kool

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 682 KB

english, 2012

59

Guanine-Rich DNA Nanocircles for the Synthesis and Characterization of Long Cytosine-Rich Telomeric DNAs

Jörg S. Hartig, Sara Fernandez-Lopez, Eric T. Kool

Journal:

Year:

2005

Language:

english

File:

PDF, 209 KB

english, 2005

60

Enzymatic Synthesis of Fluorescent Oligomers Assembled on a DNA Backbone

Younjin Cho, Eric T. Kool

Journal:

Year:

2006

Language:

english

File:

PDF, 243 KB

english, 2006

61

RNA-Templated Chemistry in Cells: Discrimination of Escherichia, Shigella and Salmonella Bacterial Strains With a New Two-Color FRET Strategy

Adam P. Silverman, Ellen J. Baron, Eric T. Kool

Journal:

Year:

2006

Language:

english

File:

PDF, 352 KB

english, 2006

62

Quenching of Fluorescent Nucleobases by Neighboring DNA: The “Insulator” Concept

James N. Wilson, Younjin Cho, Samuel Tan, Andrea Cuppoletti, Eric T. Kool

Journal:

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

63

Polymerase Amplification, Cloning, and Gene Expression of Benzo-Homologous “yDNA” Base Pairs

Jijumon Chelliserrykattil, Haige Lu, Alex H. F. Lee, Eric T. Kool

Journal:

Year:

2008

Language:

english

File:

PDF, 280 KB

english, 2008

64

7-Azidomethoxy-Coumarins as Profluorophores for Templated Nucleic Acid Detection

Raphael M. Franzini, Eric T. Kool

Journal:

Year:

2008

Language:

english

File:

PDF, 434 KB

english, 2008

65

Structure and Replication of yDNA: A Novel Genetic Set Widened by Benzo-Homologation

Haige Lu, Stephen R. Lynch, Alex H. F. Lee, Eric T. Kool

Journal:

Year:

2009

Language:

english

File:

PDF, 540 KB

english, 2009

66

Templated Chemistry for Sequence-Specific Fluorogenic Detection of Duplex DNA

Hao Li, Raphael M. Franzini, Christopher Bruner, Prof. Dr. Eric T. Kool

Journal:

Year:

2010

Language:

english

File:

PDF, 350 KB

english, 2010

67

Solid-Phase Synthesis and Screening of Macrocyclic Nucleotide-Hybrid Compounds Targeted to Hepatitis C NS5B

Michael Smietana, Robert B. Johnson, Q. May Wang, Eric T. Kool

Journal:

Chemistry - A European Journal

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

68

Fluorous Base-Pairing Effects in a DNA Polymerase Active Site

Jacob S. Lai, Eric T. Kool

Journal:

Chemistry - A European Journal

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

69

Steric Effects in RNA Interference: Probing the Influence of Nucleobase Size and Shape

Alvaro Somoza, Adam P. Silverman, Rand M. Miller, Jijumon Chelliserrykattil, Eric T. Kool

Journal:

Chemistry - A European Journal

Year:

2008

Language:

english

File:

PDF, 495 KB

english, 2008

70

Polyfluorophore Labels on DNA: Dramatic Sequence Dependence of Quenching

Yin Nah Teo, James N. Wilson , Eric T. Kool

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 409 KB

english, 2009

71

Two Successive Reactions on a DNA Template: A Strategy for Improving Background Fluorescence and Specificity in Nucleic Acid Detection

Dr. Raphael M. Franzini, Prof. Dr. Eric T. Kool

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

72

Differentiating a Diverse Range of Volatile Organic Compounds with Polyfluorophore Sensors Built on a DNA Scaffold

Dr. Florent Samain, Dr. Nan Dai, Prof. Dr. Eric T. Kool

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 834 KB

english, 2011

73

ChemInform Abstract: Novel Nucleoside Analogues with Fluorophores Replacing the DNA Base

Christoph Straessler, Newton E. Davis, Eric T. Kool

Journal:

Year:

2000

File:

PDF, 26 KB

2000

74

ChemInform Abstract: Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes.

Juan C. Morales, Eric T. Kool

Journal:

Year:

2000

File:

PDF, 23 KB

2000

75

ChemInform Abstract: Mimicking the Structure and Function of DNA: Insights into DNA Stability and Replication

Eric T. Kool, Juan C. Morales, Kevin M. Guckian

Journal:

Year:

2000

File:

PDF, 25 KB

2000

76

A Highly Effective Nonpolar Isostere of Deoxyguanosine (I): Synthesis, Structure, Stacking, and Base Pairing.

Bryan M. O'Neill, Jessica E. Ratto, Kristi L. Good, Deborah C. Tahmassebi, Sandra A. Helquist, Juan C. Morales, Eric T. Kool

Journal:

Year:

2003

File:

PDF, 82 KB

2003

77

Replacing the Nucleobases in DNA with Designer Molecules

Journal:

Year:

2003

File:

PDF, 48 KB

2003

78

A Set of Nonpolar Thymidine Nucleoside Analogues with Gradually Increasing Size

Tae Woo Kim, Eric T. Kool

Journal:

Year:

2005

File:

PDF, 10 KB

2005

79

ChemInform Abstract: Chemistry of Nucleic Acids: Impacts in Multiple Fields

Omid Khakshoor, Eric T. Kool

Journal:

Year:

2011

File:

PDF, 18 KB

2011

80

ChemInform Abstract: Fluorescent DNA-Based Enzyme Sensors

Nan Dai, Eric T. Kool

Journal:

Year:

2012

File:

PDF, 18 KB

2012

81

Identification, molecular cloning, and characterization of the chromosome 12 breakpoint cluster region of uterine leiomyomas

Eric F. P. M. Schoenmakers, Raf Mols, Sylke Wanschura, Patrick F. J. Kools, Jan M. W. Geurts, Sabine Bartnitzke, Jörn Bullerdiek, Herman Van Den Berghe, Wim J. M. De Van Ven

Journal:

Genes, Chromosomes and Cancer

Year:

1994

Language:

english

File:

PDF, 2.31 MB

english, 1994

82

Molecular characterization of mar, a multiple aberration region on human chromosome segment 12q13-q15 implicated in various solid tumors

Dr.Wim J. M. van de Ven, Eric F. P. M. Schoenmakers, Sylke Wanschura, Bernd Kazmierczak, Patrick F. J. Kools, Jan M. W. Geurts, Sabine Bartnitzke, Herman Van Den Berghe, Jörn Bullerdiek

Journal:

Genes, Chromosomes and Cancer

Year:

1995

Language:

english

File:

PDF, 774 KB

english, 1995

83

An efficient method for the synthesis of aromatic C-nucleosides

Narayan C. Chaudhuri, Eric T. Kool

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 200 KB

english, 1995

84

Model systems for understanding DNA base pairing

Andrew T Krueger, Eric T Kool

Journal:

Current Opinion in Chemical Biology

Year:

2007

Language:

english

File:

PDF, 923 KB

english, 2007

85

Redesigning the Architecture of the Base Pair: Toward Biochemical and Biological Function of New Genetic Sets

Andrew T. Krueger, Eric T. Kool

Journal:

Chemistry & Biology

Year:

2009

Language:

english

File:

PDF, 342 KB

english, 2009

86

Oligodeoxyfluorosides: strong sequence dependence of fluorescence emission

James N. Wilson, Jianmin Gao, Eric T. Kool

Journal:

Year:

2007

Language:

english

File:

PDF, 730 KB

english, 2007

87

A γ-cyclodextrin thiazolium salt holoenzyme mimic for the benzoin condensation

Ronald Breslow, Eric Kool

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 247 KB

english, 1988

88

A novel 5′-iodonucleoside allows efficient nonenzymatic ligation of single-stranded and duplex DNAs

Yanzheng Xu, Eric T. Kool

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 230 KB

english, 1997

89

A polymeric mini-stent designed to facilitate the vasectomy reversal operation. A rabbit model study

Eric J. Vrijhof, Adriaan de Bruı̈ne, August A.B. Lycklama à Nijeholt, Leo H. Koole

Journal:

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

90

Recognition of RNA by triplex formation: Divergent effects of pyrimidine C-5 methylation

Shaohui Wang, Yanzheng Xu, Eric T. Kool

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 755 KB

english, 1997

91

Bi-stranded, multisite replication of a base pair between difluorotoluene and adenine: confirmation by ‘inverse’ sequencing

Dongyu Liu, Sean Moran, Eric T. Kool

Journal:

Chemistry & Biology

Year:

1997

Language:

english

File:

PDF, 2.85 MB

english, 1997

92

Triplex-directed self-assembly of an artificial sliding clamp on duplex DNA

Kevin Ryan, Eric T. Kool

Journal:

Chemistry & Biology

Year:

1998

Language:

english

File:

PDF, 2.90 MB

english, 1998

93

Mimicry of the hepatitis delta virus replication cycle mediated by synthetic circular oligodeoxynucleotides

Amy M Diegelman, Eric T Kool

Journal:

Chemistry & Biology

Year:

1999

Language:

english

File:

PDF, 2.08 MB

english, 1999

94

Synthetically modified DNAs as substrates for polymerases

Journal:

Current Opinion in Chemical Biology

Year:

2000

Language:

english

File:

PDF, 161 KB

english, 2000

95

Biopolymers: Editorial overview

Michael H Hecht, Ole Hindsgaul, Eric T Kool

Journal:

Current Opinion in Chemical Biology

Year:

1998

Language:

english

File:

PDF, 282 KB

english, 1998

96

A long range restriction map spanning the myxoid liposarcoma breakpoint in the q13-14 region of human chromosome 12

Anne Forus, Patrick F. J. Kools, Eric F. P. M. Schoenmakers, Wim J. M. Ven, Ola Myklebost

Journal:

Year:

1994

Language:

english

File:

PDF, 1.55 MB

english, 1994

97

Topological modification of oligonucleotides for potential inhibition of gene expression

Journal:

Perspectives in Drug Discovery and Design

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

98

Solvent pH, and ionic effects on the binding of single-stranded DNA by circular oligodeoxynucleotides

David J. d'Souza, Eric T. Kool

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 636 KB

english, 1994

99

The use of a newly designed nonabsorbable polymeric stent in reconstructing the vas deferens: a feasibility study in New Zealand white rabbits

Eric J. Vrijhof, Adriaan De Bruine, Aeilko H. Zwinderman, August A.B. Lycklama À Nijeholt, Leo H. Koole

Journal:

BJU International

Year:

2005

Language:

english

File:

PDF, 235 KB

english, 2005

100

10.1038/2146

Kool, Eric T., Matray, Tracy J.

Journal:

Nature Neuroscience

Year:

1998

Language:

english

File:

PDF, 43 KB

english, 1998