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51

Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

Phillips, Sarah, Prat, Aleix, Sedic, Maja, Proia, Theresa, Wronski, Ania, Mazumdar, Sohini, Skibinski, Adam, Shirley, Stephanie H., Perou, Charles M., Gill, Grace, Gupta, Piyush B., Kuperwasser, Charl

Journal:

Stem Cell Reports

Year:

2014

Language:

english

File:

PDF, 3.72 MB

english, 2014

52

Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

Gross, Kayla M., Zhou, Wenhui, Breindel, Jerrica L., Ouyang, Jian, Jin, Dexter X., Sokol, Ethan S., Gupta, Piyush B., Huber, Kathryn, Zou, Lee, Kuperwasser, Charlotte

Journal:

Year:

2019

Language:

english

File:

PDF, 4.25 MB

english, 2019

53

337 HEALTH STATUS OF PATIENTS WHO RECEIVED TAPENTADOL PROLONGED RELEASE DURING AN OPEN-LABEL EXTENSION STUDY

B. Kuperwasser, E. McCann, I. Van Hove, R. Lange, T. Häufel, M. Etropolski

Journal:

Osteoarthritis and Cartilage

Year:

2010

Language:

english

File:

PDF, 60 KB

english, 2010

54

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

Piyush B. Gupta, Tamer T. Onder, Guozhi Jiang, Kai Tao, Charlotte Kuperwasser, Robert A. Weinberg, Eric S. Lander

Journal:

Year:

2009

Language:

english

File:

PDF, 2.28 MB

english, 2009

55

Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases

Zhu, C., Gupta, A., Hall, V. L., Rayla, A. L., Christensen, R. G., Dake, B., Lakshmanan, A., Kuperwasser, C., Stormo, G. D., Wolfe, S. A.

Journal:

Nucleic Acids Research

Year:

2013

Language:

english

File:

PDF, 2.43 MB

english, 2013

56

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

Chaffer, C. L., Brueckmann, I., Scheel, C., Kaestli, A. J., Wiggins, P. A., Rodrigues, L. O., Brooks, M., Reinhardt, F., Su, Y., Polyak, K., Arendt, L. M., Kuperwasser, C., Bierie, B., Weinberg, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

57

From The Cover: Reconstruction of functionally normal and malignant human breast tissues in mice

Kuperwasser, C., Chavarria, T., Wu, M., Magrane, G., Gray, J. W., Carey, L., Richardson, A., Weinberg, R. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 638 KB

english, 2004

58

Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon

Ni, Thomas K., Elman, Jessica S., Jin, Dexter X., Gupta, Piyush B., Kuperwasser, Charlotte

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.53 MB

english, 2018

59

Reconstruction of human mammary tissues in a mouse model

Proia, David A, Kuperwasser, Charlotte

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 548 KB

english, 2006

60

Contributions of estrogen to ER-negative breast tumor growth

Piyush B. Gupta, Charlotte Kuperwasser

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 378 KB

english, 2006

61

Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice

Wu, M., Jung, L., Cooper, A. B., Fleet, C., Chen, L., Breault, L., Clark, K., Cai, Z., Vincent, S., Bottega, S., Shen, Q., Richardson, A., Bosenburg, M., Naber, S. P., DePinho, R. A., Kuperwasser, C.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 1.30 MB

english, 2009

62

Reply to Maguer-Satta et al.: Revisiting the mammosphere assay

Keller, P. J., Kuperwasser, C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 685 KB

english, 2011

63

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

Christine M. Fillmore, Piyush B. Gupta, Jenny A. Rudnick, Silvia Caballero, Patricia J. Keller, Eric S. Lander, Charlotte Kuperwasser and Geoffrey M. Wahl

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.61 MB

english, 2010

64

Assessment of the role of circulating breast cancer cells in tumor formation and metastatic potential using in vivo flow cytometry

Hwu, Derrick, Boutrus, Steven, Greiner, Cherry, DiMeo, Theresa, Kuperwasser, Charlotte, Georgakoudi, Irene

Journal:

Journal of Biomedical Optics

Year:

2011

Language:

english

File:

PDF, 389 KB

english, 2011

65

The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells

Miceli, Caterina, Roccio, Federica, Penalva-Mousset, Lucille, Burtin, Martine, Leroy, Christine, Nemazanyy, Ivan, Kuperwasser, Nicolas, Pontoglio, Marco, Friedlander, GÃ©rard, Morel, Etienne, Terzi, F

Journal:

Nature Cell Biology

Year:

2020

File:

PDF, 10.88 MB

2020

66

334 INCIDENCE AND SEVERITY OF GASTROINTESTINAL TREATMENT-EMERGENT ADVERSE EVENTS IN PATIENTS TREATED WITH TAPENTADOL EXTENDED RELEASE (ER) OR OXYCODONE CONTROLLED RELEASE (CR) FOR RELIEF OF CHRONIC OSTEOARTHRITIS KNEE PAIN

B. Kuperwasser, T. Häufel, K. Kelly, M. Etropolski, F. Laschewski, A. Okamoto, A. Steup, I. Van Hove, C. Rauschkolb

Journal:

Osteoarthritis and Cartilage

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

67

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

Piyush B. Gupta, Christine M. Fillmore, Guozhi Jiang, Sagi D. Shapira, Kai Tao, Charlotte Kuperwasser, Eric S. Lander

Journal:

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

68

Stroma in breast development and disease

Lisa M. Arendt, Jenny A. Rudnick, Patricia J. Keller, Charlotte Kuperwasser

Journal:

Seminars in Cell & Developmental Biology

Year:

2010

Language:

english

File:

PDF, 545 KB

english, 2010

69

Poster 50: Health-related Functional Status Evaluations in Patients with Osteoarthritis Pain Treated With Tapentadol Extended Release

Brigitte Kuperwasser, Marc Afilalo, Mila S. Etropolski, Alison Greene, Juergen Haeussler, Kathleen M. Kelly, Bernd Lange

Journal:

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

70

Stroma: Tumor Agonist or Antagonist

Proia, David A., Kuperwasser, Charlotte

Journal:

Year:

2005

File:

PDF, 395 KB

2005

71

COMPARISON OF ALFENTANIL AND 5UFENTANIL IN THE AMBULATORY SURGERY PROCEDURE WHEN USED IN BALANCED ANESTHESIA TECHNIQUE

Kuperwasser, B, Dahl, M, McSweeney, T O, Howie, M B

Journal:

Anesthesia & Analgesia

Year:

1988

File:

PDF, 232 KB

1988

72

Poster 51: Health-related Outcomes Associated With Tapentadol Extended Release and Oxycodone Controlled Release Treatment for Chronic Low Back or Osteoarthritis Pain: Results of a Randomized, Open-label, Phase 3 Long-term Safety Trial

Bettyanne McCann, Mila S. Etropolski, Jane S. Gilbert, Alison Greene, Brigitte Kuperwasser, Claudia Lange, Robert Lange, Achim Steup

Journal:

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

73

Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor-Negative Cancers

Gupta, P. B., Proia, D., Cingoz, O., Weremowicz, J., Naber, S. P., Weinberg, R. A., Kuperwasser, C.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

74

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

Pashos, Evanthia E., Park, YoSon, Wang, Xiao, Raghavan, Avanthi, Yang, Wenli, Abbey, Deepti, Peters, Derek T., Arbelaez, Juan, Hernandez, Mayda, Kuperwasser, Nicolas, Li, Wenjun, Lian, Zhaorui, Liu, Y

Journal:

Year:

2017

Language:

english

File:

PDF, 3.76 MB

english, 2017

75

336 TAPENTADOL EXTENDED RELEASE FOR THE RELIEF OF CHRONIC OSTEOARTHRITIS KNEE PAIN: RESULTS FROM THE EUROQOL-5 DIMENSION (EQ-5D) AND WESTERN ONTARIO AND MACMASTER UNIVERSITIES OSTEOARTHRITIS INDEX (WOMAC) QUESTIONNAIRES

C. Rauschkolb, B. Lange, B. Kuperwasser, K. Kelly, A. Okamoto, I. Van Hove, M. Etropolski

Journal:

Osteoarthritis and Cartilage

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

76

Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met

Kelly L Mueller, Julie M Madden, Gina L Zoratti, Charlotte Kuperwasser, Karin List, Julie L Boerner

Journal:

Breast Cancer Research

Year:

2012

Language:

english

File:

PDF, 501 KB

english, 2012

77

Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow-Derived Monocytes

Iyer, V., Klebba, I., McCready, J., Arendt, L. M., Betancur-Boissel, M., Wu, M.-F., Zhang, X., Lewis, M. T., Kuperwasser, C.

Journal:

Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

78

The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis

Xu, Kun, Tian, Xuejun, Oh, Sun Y., Movassaghi, Mohammad, Naber, Stephen P., Kuperwasser, Charlotte, Buchsbaum, Rachel J.

Journal:

Breast Cancer Research

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

79

CoREST1 Promotes Tumor Formation and Tumor Stroma Interactions in a Mouse Model of Breast Cancer

Mazumdar, Sohini, Arendt, Lisa M., Phillips, Sarah, Sedic, Maja, Kuperwasser, Charlotte, Gill, Grace, Tan, Ming

Journal:

Year:

2015

Language:

english

File:

PDF, 5.02 MB

english, 2015

80

337 EVALUATION OF LONG-TERM TREATMENT WITH TAPENTADOL EXTENDED RELEASE AND OXYCODONE CONTROLLED RELEASE IN PATIENTS WITH CHRONIC LOW BACK OR OSTEOARTHRITIS PAIN: RESULTS FROM PATIENT AND PHYSICIAN GLOBAL ASSESSMENTS AND THE EUROQOL 5 DIMENSION QUESTIONNAIRE

B. Kuperwasser, R. Lange, B. McCann, A. Greene, M. Etropolski, B. Lange, J. Gilbert, A. Okamoto, A. Steup, C. Rauschkolb

Journal:

Osteoarthritis and Cartilage

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

81

The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer

Zhou, Wenhui, Ni, Thomas K., Wronski, Ania, Glass, Benjamin, Skibinski, Adam, Beck, Andrew, Kuperwasser, Charlotte

Journal:

Year:

2016

Language:

english

File:

PDF, 3.63 MB

english, 2016

82

Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells

Rudnick, Jenny A., Arendt, Lisa M., Klebba, Ina, Hinds, John W., Iyer, Vandana, Gupta, Piyush B., Naber, Stephen P., Kuperwasser, Charlotte, Shioda, Toshi

Journal:

Year:

2011

Language:

english

File:

PDF, 2.81 MB

english, 2011

83

Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites

Montesion, Meagan, Williams, Zachary H., Subramanian, Ravi P., Kuperwasser, Charlotte, Coffin, John M.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.56 MB

english, 2018

84

Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: Significance of p53 status and apoptosis

Daniel Medina, L. Clifton Stephens, Pedro J. Bonilla, C. Annette Hollmann, Denise Schwahn, Charlotte Kuperwasser, D. Joseph Jerry, Janet S. Butel, Raymond E. Meyn

Journal:

Molecular Carcinogenesis

Year:

1998

Language:

english

File:

PDF, 573 KB

english, 1998

85

Mobilization of Bone Marrow Stem Cell Populations as a Result of Unopposed Estrogen: A Mechanism for Estrogen-Mediated Angiogenesis

M.D. Chan, D.E. Wazer, D. Hwu, S. Boutrus, I. Georgakoudi, C. Kuperwasser

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 40 KB

english, 2007

86

Disease models of breast cancer

Piyush B. Gupta, Charlotte Kuperwasser

Journal:

Drug Discovery Today: Disease Models

Year:

2004

Language:

english

File:

PDF, 523 KB

english, 2004

87

Alterations of the HBP1 Transcriptional Repressor Are Associated with Invasive Breast Cancer

Paulson, K. E., Rieger-Christ, K., McDevitt, M. A., Kuperwasser, C., Kim, J., Unanue, V. E., Zhang, X., Hu, M., Ruthazer, R., Berasi, S. P., Huang, C.-Y., Giri, D., Kaufman, S., Dugan, J. M., Blum, J.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 679 KB

english, 2007

88

EFFECT OF ANESlHESIA INDUCTION IN THE RELATION BETWEEN ELECTRICAL AND ELECTROMECHANICAL SYSTOLE AND DIASTOLIC TIME

McDonald, J, Kuperwasser, B, Nunziata, E, Boudoulas, H

Journal:

Anesthesia & Analgesia

Year:

1988

File:

PDF, 203 KB

1988

89

Mechanisms of HERV-K (HML-2) transcription during human mammary epithelial cell transformation

Montesion, Meagan, Bhardwaj, Neeru, Williams, Zachary H., Kuperwasser, Charlotte, Coffin, John M.

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 2.53 MB

english, 2017

90

Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction‐like phenotype in aged mice

Katsimpardi, Lida, Kuperwasser, Nicolas, Camus, Claire, Moigneu, Carine, Chiche, Aurélie, Tolle, Virginie, Li, Han, Kokovay, Erzsebet, Lledo, Pierre‐Marie

Journal:

Year:

2019

Language:

english

File:

PDF, 1.24 MB

english, 2019

91

The Effect of Radiation on Tumorigenesis and Clonogenic Survival of Breast Cancer Stem Cells

K.E. Huber, D.E. Wazer, C. Kuperwasser

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

92

The Tumor Stromal Microenvironment as Modulator of Malignant Behavior

Charlotte Kuperwasser

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2010

Language:

english

File:

PDF, 66 KB

english, 2010

93

The origin of breast tumor heterogeneity

Skibinski, A, Kuperwasser, C

Journal:

Year:

2015

Language:

english

File:

PDF, 597 KB

english, 2015

94

Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression

Nagiec, Marek M., Skepner, Adam P., Negri, Joseph, Eichhorn, Michelle, Kuperwasser, Nicolas, Comer, Eamon, Muncipinto, Giovanni, Subramanian, Aravind, Clish, Clary, Musunuru, Kiran, Duvall, Jeremy R.,

Journal:

Year:

2015

Language:

english

File:

PDF, 4.61 MB

english, 2015

95

The role of fibroblast Tiam1 in tumor cell invasion and metastasis

Xu, K, Rajagopal, S, Klebba, I, Dong, S, Ji, Y, Liu, J, Kuperwasser, C, Garlick, J A, Naber, S P, Buchsbaum, R J

Journal:

Year:

2010

Language:

english

File:

PDF, 771 KB

english, 2010

96

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

James W. Rocco, Chee-Onn Leong, Nicolas Kuperwasser, Maurice Phillip DeYoung, Leif W. Ellisen

Journal:

Year:

2006

Language:

english

File:

PDF, 742 KB

english, 2006

97

Asp338 Controls Hydride Transfer in Escherichia coli IMP Dehydrogenase †

Kerr, Kathleen M., Digits, Jennifer A., Kuperwasser, Nicolas, Hedstrom, Lizbeth

Journal:

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

98

Erratum to: Efficacy and safety of tapentadol prolonged release for chronic osteoarthritis pain and low back pain

Bernd Lange, Brigitte Kuperwasser, Akiko Okamoto, Achim Steup, Thomas Häufel, Judy Ashworth, Mila Etropolski

Journal:

Advances in Therapy

Year:

2010

Language:

english

File:

PDF, 103 KB

english, 2010

99

Cyclin D1 Kinase Activity Is Required for the Self-Renewal of Mammary Stem and Progenitor Cells that Are Targets of MMTV-ErbB2 Tumorigenesis

Rinath Jeselsohn, Nelson E. Brown, Lisa Arendt, Ina Klebba, Miaofen G. Hu, Charlotte Kuperwasser, Philip W. Hinds

Journal:

Year:

2010

Language:

english

File:

PDF, 1.90 MB

english, 2010

100

A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models

Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A.K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, M

Journal:

Year:

2013

Language:

english

File:

PDF, 2.11 MB

english, 2013

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