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51

The Role of Disulfide Bond C191-C220 in Trypsin and Chymotrypsin

Éva Várallyay, Zsolt Lengyel, László Gráf, László Szilágyi

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 109 KB

english, 1997

52

Differential behaviour of LPH-(61–91)-peptide in different model systems: Comparison of the opioid activities of LPH-(61–91)-peptide and its fragments

András Z. Rónai, László Gráf, József I. Székely, Zsuzsa Dunai-Kovács, Sándor Bajusz

Journal:

Year:

1977

Language:

english

File:

PDF, 238 KB

english, 1977

53

When the Surface Tells What Lies Beneath: Combinatorial Phage-display Mutagenesis Reveals Complex Networks of Surface–Core Interactions in the Pacifastin Protease Inhibitor Family

Borbála Szenthe, András Patthy, Zoltán Gáspári, Adrienna Katalin Kékesi, László Gráf, Gábor Pál

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 3.18 MB

english, 2007

54

Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r

József Kardos, Veronika Harmat, Anna Palló, Orsolya Barabás, Katalin Szilágyi, László Gráf, Gábor Náray-Szabó, Yuji Goto, Péter Závodszky, Péter Gál

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 867 KB

english, 2008

55

Effects of Serpin Binding on the Target Proteinase: Global Stabilization, Localized Increased Structural Flexibility, and Conserved Hydrogen Bonding at the Active Site †

Kaslik, Gyula, Kardos, József, Szabó, Erika, Szilágyi, László, Závodszky, Péter, Westler, William M., Markley, John L., Gráf, László

Journal:

Year:

1997

Language:

english

File:

PDF, 201 KB

english, 1997

56

The differential specificity of chymotrypsin A and B is determined by amino acid 226

Péter Hudáky, , Gyula Kaslik, , István Venekei, László Gráf

Journal:

Year:

1999

Language:

english

File:

PDF, 252 KB

english, 1999

57

Studies on the conformation of β-endorphin and its constituent fragments in water and trifluoroethanol by CD spectroscopy

Miklós Hollósi, Márton Kajtár, László Gráf

Journal:

Year:

1977

Language:

english

File:

PDF, 343 KB

english, 1977

58

Handbook of Proteolytic Enzymes || Chymotrypsin

Year:

2013

Language:

english

File:

PDF, 298 KB

english, 2013

59

Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database

Maurer, Britta, Graf, Nicole, Michel, Beat A, Müller-Ladner, Ulf, Czirják, László, Denton, Christopher P, Tyndall, Alan, Metzig, Carola, Lanius, Vivian, Khanna, Dinesh, Distler, Oliver

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 525 KB

english, 2015

60

Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: Role of local internal viscosity in protein dynamics

Júlia Tóth, Zoltán Simon, Péter Medveczky, Linda Gombos, Balázs Jelinek, László Szilágyi, László Gráf, András Málnási-Csizmadia

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 267 KB

english, 2007

61

Action of Thrombin on Ovine, Bovine and Human Pituitary Growth Hormones

Lászlo GRÁF, Erzsébet BARÁT, János BORVENDÉG, Ilona HERMANN, András PATTHY

Journal:

Year:

1976

Language:

english

File:

PDF, 656 KB

english, 1976

62

Isolation, biochemical characterization, and molecular modeling of American lobster digestive cathepsin D1

Liliana Rojo, Rogerio Sotelo-Mundo, Fernando García-Carreño, László Gráf

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 508 KB

english, 2010

63

Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4

Péter Medveczky, József Antal, András Patthy, Katalin Kékesi, Gábor Juhász, László Szilágyi, László Gráf

Journal:

Year:

2006

Language:

english

File:

PDF, 344 KB

english, 2006

64

Extended Intermolecular Interactions in a Serine Protease–Canonical Inhibitor Complex Account for Strong and Highly Specific Inhibition

Krisztián Fodor, Veronika Harmat, Csaba Hetényi, József Kardos, József Antal, András Perczel, András Patthy, Gergely Katona, László Gráf

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 831 KB

english, 2005

65

Substrate conformation directs selective enzymic cleavage of β-lipotropin into β-endorphin

László Gráf, Miklós Hollósi

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 979 KB

english, 1980

66

Isolation and characterization of a protease inhibitor from Acacia karroo with a common combining loop and overlapping binding sites for chymotrypsin and trypsin

Patthy, András, Molnár, Tamás, Porrogi, Pálma, Naudé, Ryno, Gráf, László

Journal:

Archives of Biochemistry and Biophysics

Year:

2015

Language:

english

File:

PDF, 1.94 MB

english, 2015

67

Expression of rat chymotrypsinogen in yeast: a study on the structural and functional significance of the chymotrypsinogen propeptide

István Venekei, László Gráf, William J. Rutter

Journal:

Year:

1996

Language:

english

File:

PDF, 557 KB

english, 1996

68

Enkephalin-hydrolyzing peptidases of rat brain membranes: Are they topographically/functionally coupled to opiate receptors?

László Gráf, András Nagy, Abel Lajtha

Journal:

Year:

1982

Language:

english

File:

PDF, 279 KB

english, 1982

69

(Hydroxyalkyl)cob(III)alamins as Competitive Inhibitors in Coenzyme B12-Dependent Enzymic Reactions: 1H-NMR Structure Analysis and Kinetic Studies with Glycerol Dehydratase and Diol Dehydratase

László Poppe, William E. Hull, Rainer Nitsche, Torsten Graf, Erhard Stupperich, János Rétey

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 167 KB

english, 1999

70

Serum fetuin-A in metabolic and inflammatory pathways in patients with myocardial infarction

Krisztián Vörös, László Gráf Jr, Zoltán Prohászka, László Gráf, Péter Szenthe, Edit Kaszás, Zoltán Böröcz, Károly Cseh, László Kalabay

Journal:

European Journal of Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 158 KB

english, 2011

71

Studies on prolactin : 46. Preferential cleavage of the Arg125 -Leu126 peptide bond of ovine hormone with immobilized trypsin

Journal:

Chemical Biology & Drug Design

Year:

1982

Language:

english

File:

PDF, 271 KB

english, 1982

72

Two Mutations in Rat Trypsin Confer Resistance against Autolysis

Éva Várallyay, Gábor Pál, András Patthy, László Szilágyi, László Gráf

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 117 KB

english, 1998

73

Attempts to convert chymotrypsin to trypsin

István Venekei, László Szilágyi, László Gráf, William J. Rutter

Journal:

Year:

1996

Language:

english

File:

PDF, 538 KB

english, 1996

74

Characterization of a trypsin-like serine protease of activated B cells mediating the cleavage of surface proteins

Anna Biró, Zoltán Hérincs, Erzsébet Fellinger, László Szilágyi, Zsuzsa Barad, János Gergely, László Gráf, Gabriella Sármay

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2003

Language:

english

File:

PDF, 430 KB

english, 2003

75

Specific high-affinity binding sites for a synthetic gliadin heptapeptide on human peripheral blood lymphocytes

Donald G. Payan, Károly Horváth, László Gráf

Journal:

Year:

1987

Language:

english

File:

PDF, 358 KB

english, 1987

76

On the primary structure of pituitary bovine growth hormone

László Gráf, Choh Hao Li

Journal:

Biochemical and Biophysical Research Communications

Year:

1974

Language:

english

File:

PDF, 323 KB

english, 1974

77

Further evidence for the neuroleptic-like activity of γ-endorphin

Király, Ildikó, Tapfer, Marianna, Borsy, József, Gráf, László

Journal:

Year:

1981

Language:

english

File:

PDF, 352 KB

english, 1981

78

[Part 2: Biological Sciences] || Human Somatotropin: Covalent Reconstitution of Two Polypeptide Contiguous Fragments with Thrombin

László Gráf and Choh Hao Li

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 1.01 MB

english, 1981

79

Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin

Graf, Laszlo, Craik, Charles S., Patthy, Andras, Roczniak, Steven, Fletterick, Robert J., Rutter, William J.

Journal:

Year:

1987

Language:

english

File:

PDF, 2.70 MB

english, 1987

80

Action of plasmin on oxidized bovine growth hormone

László Gráf, Choh Hao Li

Journal:

Archives of Biochemistry and Biophysics

Year:

1974

Language:

english

File:

PDF, 371 KB

english, 1974

81

Is there correlation between analgesic potency and biodegradation of enkephalin analogs?

Sándor Bajusz, András Patthy, Ágnes Kenessey, László Gráf, József I. Székely, András Z. Rónai

Journal:

Biochemical and Biophysical Research Communications

Year:

1978

Language:

english

File:

PDF, 414 KB

english, 1978

82

Human Pituitary Growth Hormone: Isolation and Properties of Two Biologically Active Fragments from Plasmin Digests

Choh Hao Li and Laszlo Graf

Journal:

Proceedings of the National Academy of Sciences

Year:

1974

Language:

english

File:

PDF, 965 KB

english, 1974

83

Probing Conformational Plasticity of the Activation Domain of Trypsin: The Role of Glycine Hinges †

Gombos, Linda, Kardos, József, Patthy, András, Medveczky, Péter, Szilágyi, László, Málnási-Csizmadia, András, Gráf, László

Journal:

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

84

Serum Heat Shock Protein 70, as a Potential Biomarker for Small Cell Lung Cancer

Balázs, Madaras, Zsolt, Horváth, László, Gráf, Gabriella, Gálffy, Lilla, Tamási, Gyula, Ostoros, Balázs, Döme, Éva, Mórocz, Zoltán, Bártfai, Zoltán, Prohászka, Judit, Kocsis

Journal:

Pathology & Oncology Research

Year:

2017

Language:

english

File:

PDF, 511 KB

english, 2017

85

NALOXONE ANTAGONISES EFFECT OF α-GLIADIN ON LEUCOCYTE MIGRATION IN PATIENTS WITH COELIAC DISEASE

Horváth, Károly, Walcz, Erzsebét, Gráf, László, Bodánszky, Hedvig, Schuler, Dezsö

Journal:

Year:

1985

Language:

english

File:

PDF, 310 KB

english, 1985

86

Relationship Between Internal Friction and the Roughness of the Energy Landscape of Protein Conformational Changes

Rauscher, Anna Á., Simon, Zoltán, Szöllősi, Gergely J., Gráf, László, Derényi, Imre, Malnasi-Csizmadia, Andras

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

87

Biochemical characterization of Acacia schweinfurthii serine proteinase inhibitor

Odei-Addo, Frank, Frost, Carminita, Smith, Nanette, Ogawa, Tomohisa, Muramoto, Koji, Oliva, Maria Luiza Vilela, Gráf, László, Naude, Ryno

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 774 KB

english, 2014

88

Die Entwicklung des Leitungssystems im Stengel von Bidens tripartitus (L.)

Gráf, László

Journal:

Flora oder Allgemeine Botanische Zeitung

Year:

1938

Language:

german

File:

PDF, 7.45 MB

german, 1938

89

Mutant rat trypsin selectively cleaves tyrosyl peptide bonds

Gábor Pál, András Patthy, József Antal, László Gráf

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 340 KB

english, 2004

90

Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes

Krisztián Tárnok, László Szilágyi, Tímea Berki, Péter Németh, László Gráf, Katalin Schlett

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 755 KB

english, 2010

91

Human somatotropin : 61. A simple method to predict potential of somatotropin fragments for noncovalent recombination by radioreceptor assay

CHRISTOPHER H.K. CHENG, LÁSZLÓ GRÁF, CHOH HAO LI

Journal:

Chemical Biology & Drug Design

Year:

1982

Language:

english

File:

PDF, 169 KB

english, 1982

92

β-Endorphin inhibits met-enkephalin breakdown by a brain aminopeptidase: Structure-activity relationships

Koon-Sea Hui, László Gráf, Abel Lajtha

Journal:

Biochemical and Biophysical Research Communications

Year:

1982

Language:

english

File:

PDF, 344 KB

english, 1982

93

Neuropeptides may regulate neuropeptide metabolism in the brain

László Gráf, Koon-Sea Hui, Amos Neidle, Abel Lajtha

Journal:

Year:

1982

Language:

english

File:

PDF, 351 KB

english, 1982

94

The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease

Erika Szabó, Zsolt Böcskei, Gábor Náray-Szabó, László Gráf

Journal:

Year:

1999

Language:

english

File:

PDF, 703 KB

english, 1999

95

Structural and functional integrity of specificity and catalytic sites of trypsin

LÁSZLÓ GRÁF, GYÖRGY HEGYI, ISTVÁN LIKÓ, JÓZSEF HEPP, KÁLMÁN MEDZIHRADSZKY, CHARLES S. CRAIK, WILLIAM J. RUTTER

Journal:

Chemical Biology & Drug Design

Year:

1988

Language:

english

File:

PDF, 488 KB

english, 1988

96

Met-enkephalin attenuates morphine tolerance in rats

László Gráf, Erzsébet Miglécz, Sándor Bajusz, Jozsef I. Székely

Journal:

European Journal of Pharmacology

Year:

1979

Language:

english

File:

PDF, 151 KB

english, 1979

97

Action of Cathepsin D on Human $\beta $-lipotropin: A Possible Source of Human ``$\beta $-melanotropin''

Erzsebet Barat, Andras Patthy and Laszlo Graf

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 781 KB

english, 1979

98

Isolation and properties of two biologically active fragments from limited tryptic hydrolysis of bovine and ovine pituitary growth hormones

Graf, Laszlo, Li, Choh Hao

Journal:

Year:

1974

Language:

english

File:

PDF, 803 KB

english, 1974

99

Analytical chemical laboratory exercises on basic and advanced level at the Technical University Budapest

E. Graf-Harsányi, László Bezúr, Zsófia Fehér

Journal:

Analytical and Bioanalytical Chemistry

Year:

1997

Language:

english

File:

PDF, 17 KB

english, 1997

100

Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P1 and P1′ residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor

Zulfiquar Malik, Sumaira Amir, Gábor Pál, Zsuzsa Buzás, Éva Várallyay, József Antal, Zoltán Szilágyi, Károly Vékey, Bence Asbóth, András Patthy, László Gráf

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1999

Language:

english

File:

PDF, 247 KB

english, 1999

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