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51

Determination of steroid estrogens in wastewater by high performance liquid chromatography–tandem mass spectrometry

Y.K.K. Koh, T.Y. Chiu, A. Boobis, E. Cartmell, J.N. Lester, M.D. Scrimshaw

Journal:

Journal of Chromatography A

Year:

2007

Language:

english

File:

PDF, 407 KB

english, 2007

52

The significance of sample mass in the analysis of steroid estrogens in sewage sludges and the derivation of partition coefficients in wastewaters

T.Y. Chiu, Y.K.K. Koh, N. Paterakis, A.R. Boobis, E. Cartmell, K.H. Richards, J.N. Lester, M.D. Scrimshaw

Journal:

Journal of Chromatography A

Year:

2009

Language:

english

File:

PDF, 137 KB

english, 2009

53

The future of mixture toxicology

Journal:

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

54

Proteomic analysis of the differential effects of estrogens on human breast cancer cells

Zheying Zhu, Alan R. Boobis, Robert J. Edwards

Journal:

Year:

2007

Language:

english

File:

PDF, 123 KB

english, 2007

55

Separation of acebutolol and diacetolol diastereomers by reversed-phase high-performance liquid chromatography

A.A. Gulaid, G.W. Houghton, A.R. Boobis

Journal:

Journal of Chromatography A

Year:

1985

Language:

english

File:

PDF, 245 KB

english, 1985

56

Paracetamol oxidation: synthesis and reactivity of N-acetyl-p-benzoquinoneimine

Ian A. Blair, Alan R. Boobis, Donald S. Davies, Terry M. Cresp

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 210 KB

english, 1980

57

Cell cycle and gene expression changes in response to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in human TK6 Cells

H. Zhu, A.R. Boobis, N.J. Gooderham

Journal:

Year:

2000

Language:

english

File:

PDF, 185 KB

english, 2000

58

Heterocyclic amines and human cancer: Immunohistochemical evidence for potential metabolic competency of the colon

U. Chana, R. Edwards, T. Lightfoot, C. Garner, A. Boobis, N.J. Gooderham

Journal:

Year:

2000

Language:

english

File:

PDF, 186 KB

english, 2000

59

COST B15: modelling in drug development

Leon Aarons, Luc Balant, Alan Boobis

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 31 KB

english, 2001

60

Rapid recovery of power output in females

CHERRY, LAKOMY, BOOBIS, NEVILL

Journal:

Acta Physiologica

Year:

1998

Language:

english

File:

PDF, 180 KB

english, 1998

61

Heterocyclic amines: evaluation of their role in diet associated human cancer

N. J. GOODERHAM, S. MURRAY, A. M. LYNCH, R. J. EDWARDS, M. YADOLLAHI-FARSANI, C. BRATT, K. J. RICH, K. ZHAO, B. P. MURRAY, S. BHADRESA, S. J. CROSBIE, A. R. BOOBIS, D. S. DAVIES

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 299 KB

english, 1996

62

Dissecting the function of cytochrome P450

ALAN R. BOOBIS, ROBERT J. EDWARDS, DELYTH A. ADAMS, DONALD S. DAVIES

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 306 KB

english, 1996

63

Towards a Formative Assessment of Classroom Competencies (FACCs) for postgraduate medical trainees

Christopher S Gray, Anthony J Hildreth, Catherine Fisher, Andrew Brown, Anita Jones, Ruth Turner, Leslie Boobis

Journal:

BMC Medical Education

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

64

C-Terminal antibodies (CTAbs): A simple and broadly applicable approach for the rapid generation of protein-specific antibodies with predefined specificity

Robert J. Edwards, Amanda Wrigley, Zhonghu Bai, Michaela Bateman, Hugh Russell, Stephen Murray, Huafeng Lu, Graham W. Taylor, Alan R. Boobis, Shiranee Sriskandan

Journal:

Year:

2007

Language:

english

File:

PDF, 375 KB

english, 2007

65

Identification of estrogen-responsive proteins in MCF-7 human breast cancer cells using label-free quantitative proteomics

Zheying Zhu, Alan R. Boobis, Robert J. Edwards

Journal:

Year:

2008

Language:

english

File:

PDF, 540 KB

english, 2008

66

Is the activation of aflatoxin B1catalysed by the same form of cytochrome P-450 as that 4-hydroxylating debrisoquine in rat and/or man?

Simon Plummer, Alan R. Boobis, Donald S. Davies

Journal:

Archives of Toxicology

Year:

1986

Language:

english

File:

PDF, 559 KB

english, 1986

67

Influence of liver disease and environmental factors on hepatic monooxygenase activity in vitro

M. J. Brodie, A. R. Boobis, C. J. Bulpitt, D. S. Davies

Journal:

European Journal of Clinical Pharmacology

Year:

1981

Language:

english

File:

PDF, 846 KB

english, 1981

68

The effects of chronic alcohol ingestion and alcoholic liver disease on binding of drugs to serum proteins

M. J. Brodie, S. Boobis

Journal:

European Journal of Clinical Pharmacology

Year:

1978

Language:

english

File:

PDF, 434 KB

english, 1978

69

Protein binding of salicylate in cutaneous hepatic porphyria

Wilson H. Steele, Susan Wallace Boobis, Michael R. Moore, Abraham Goldberg, Martin J. Brodie, David J. Sumner

Journal:

European Journal of Clinical Pharmacology

Year:

1978

Language:

english

File:

PDF, 517 KB

english, 1978

70

Paracetamol toxicity in hamster isolated hepatocytes: The increase in cytosolic calcium accompanies, rather than precedes, loss of viability

Simon J. Hardwick, James W. Wilson, Duncan J. Fawthrop, Alan R. Boobis, Donald S. Davies

Journal:

Archives of Toxicology

Year:

1992

Language:

english

File:

PDF, 495 KB

english, 1992

71

Differential expression of cytochrome P450 enzymes in cultured and intact foetal rat ventral mesencephalon

E. A. Gilbert, R. J. Edwards, A. R. Boobis, S. Rose, P. Jenner

Journal:

Journal of Neural Transmission

Year:

2003

Language:

english

File:

PDF, 361 KB

english, 2003

72

The absorption of orally supplied β-alanine and its effect on muscle carnosine synthesis in human vastus lateralis

R. C. Harris, M. J. Tallon, M. Dunnett, L. Boobis, J. Coakley, H. J. Kim, J. L. Fallowfield, C. A. Hill, C. Sale, J. A. Wise

Journal:

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

73

Influence of β-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity

C. A. Hill, R. C. Harris, H. J. Kim, B. D. Harris, C. Sale, L. H. Boobis, C. K. Kim, J. A. Wise

Journal:

Year:

2007

Language:

english

File:

PDF, 199 KB

english, 2007

74

Meta-analysis of Studies of Alcohol and Breast Cancer with Consideration of the Methodological Issues

Jane Key, Susan Hodgson, Rumana Z. Omar, Tina K. Jensen, Simon G. Thompson, Alan R. Boobis, Donald S. Davies, Paul Elliott

Journal:

Cancer Causes & Control

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

75

Determination of a Human Hepatic Microsomal Scaling Factor for Predictingin VivoDrug Clearance

Nancy Hakooz, Kiyomi Ito, Helen Rawden, Helen Gill, Lynn Lemmers, Alan R. Boobis, Robert J. Edwards, David J. Carlile, Brian G. Lake, J. Brian Houston

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 369 KB

english, 2006

76

Molecular aspects of debrisoquine metabolism studied by gas chromatography mass spectrometry with electron capture negative ion chemical ionisation

S. Murray, G.C. Kahh, A.R. Boobis, D.S. Davies

Journal:

International Journal of Mass Spectrometry and Ion Physics

Year:

1983

Language:

english

File:

PDF, 229 KB

english, 1983

77

Systematic review of epidemiological evidence for use in the framework approach for analysing the human relevance of an animal mode of action

Ehi Idahosa, Lesley Rushton, Alan R. Boobis

Journal:

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

78

Mass spectrometric detection and measurement of N2-(2′-deoxyguanosin-8-yl)PhIP adducts in DNA

Sarah J Crosbie, Stephen Murray, Alan R Boobis, Nigel J Gooderham

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 183 KB

english, 2000

79

Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension

Gideon A. Paul, J Simon R. Gibbs, Alan R. Boobis, Allifia Abbas, Martin R. Wilkins

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 131 KB

english, 2005

80

Carbohydrate Ingestion Prior to Exercise Augments the Exercise-Induced Activation of the Pyruvate Dehydrogenase Complex in Human Skeletal Muscle

K. Tsintzas, C. Williams, D. Constantin-Teodosiu, E. Hultman, L. Boobis, P. Greenhaff

Journal:

Experimental Physiology

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

81

Phosphocreatine degradation in type I and type II muscle fibres during submaximal exercise in man: effect of carbohydrate ingestion

Kostas Tsintzas, Clyde Williams, Dumitru Constantin-Teodosiu, Eric Hultman, Leslie Boobis, Peter Clarys, Paul Greenhaff

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

82

Expression of Cytochromes P450 3A and P-Glycoprotein in Human Large Intestinse in Paired Tumour and Normal Samples

Roberto Canaparo, Anna Nordmark, Niklas Finnström, Stefan Lundgren, Janeric Seidegård, Bengt Jeppsson, Robert J. Edwards, Alan R. Boobis, Anders Rane

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

83

Mode of Action Considerations in the Quantitative Assessment of Tumour Responses in the Liver

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

84

Proceedings of the Final Congress of COST Action B25: Physiologically Based Pharmaco-Toxicokinetics and Dynamics, held in Athens, 26–27 May 2009

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

85

Rifampicin and vitamin D metabolism

Brodie, M J, Boobis, A R, Dollery, C T, Hillyard, Carmel J, Brown, D J, Maclntyre, I, Park, B K

Journal:

Clinical Pharmacology & Therapeutics

Year:

1980

Language:

english

File:

PDF, 329 KB

english, 1980

86

Effect of isoniazid on vitamin D metabolism and hepatic monooxygenase activity

Brodie, Martin J, Boobis, Alan R, Hillyard, Carmel J, Abeyasekera, Gamini, Maclntyre, Ian, Park, B Kevin

Journal:

Clinical Pharmacology & Therapeutics

Year:

1981

Language:

english

File:

PDF, 286 KB

english, 1981

87

Managing the challenge of chemically reactive metabolites in drug development

Park, B. Kevin, Boobis, Alan, Clarke, Stephen, Goldring, Chris E. P., Jones, David, Kenna, J. Gerry, Lambert, Craig, Laverty, Hugh G., Naisbitt, Dean J., Nelson, Sidney

Journal:

Nature Reviews Drug Discovery

Year:

2011

Language:

english

File:

PDF, 752 KB

english, 2011

88

Diazinon Is Activated by CYP2C19 in Human Liver

Wendela A. Kappers, Robert J. Edwards, Stephen Murray, Alan R. Boobis

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

89

Kinetics of Lung Macrophages Monitored in Vivo Following Particulate Challenge in Rabbits

Hazel A. Jones, Sven O. Valind, Ian C. Clark, Geraldine E. Bolden, Thomas Krausz, John B. Schofield, Alan R. Boobis, Christopher Haslett

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 466 KB

english, 2002

90

Stereoselective excretion of (3-methoxy-4-sulphooxyphenyl)ethylene glycol (MHPG sulphate) in the dog

S. Murray, A. R. Boobis, H. Frank, T. A. Baillie, D. S. Davies

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1980

Language:

english

File:

PDF, 684 KB

english, 1980

91

In vitro prediction of gastrointestinal absorption and bioavailability: an experts' meeting report

Pelkonen, Olavi, Boobis, Alan, Gundert-Remy, Ursula

Journal:

European Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

92

Reversal of acetaminophen toxicity in isolated hamster hepatocytes by dithiothreitol

Lisa B.G. Tee, Alan R. Boobis, Anthony C. Huggett, Donald S. Davies

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 11.30 MB

english, 1986

93

An inhibitory monoclonal anti-protein antibody and an anti-peptide antibody share an epitope on rat cytochrome P-450 enzymes CYP1A1 and CYP1A2

Robert J. Edwards, Bernard P. Murray, Stephen Murray, Alison M. Singleton, Donald S. Davies, Alan R. Boobis

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1993

Language:

english

File:

PDF, 977 KB

english, 1993

94

Positron emission tomography in the quantification of cellular and biochemical responses to intrapulmonary particulates

Hazel A. Jones, Kurt Hamacher, John C. Clark, John B. Schofield, Thomas Krausz, Christopher Haslett, Alan R. Boobis

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

95

Development of a Comprehensive Panel of Antibodies against the Major Xenobiotic Metabolising Forms of Cytochrome P450 in Humans

Robert J Edwards, Delyth A Adams, Patricia S Watts, Donald S Davies, Alan R Boobis

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 493 KB

english, 1998

96

Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways

Roque Bort, Katherine Macé, Alan Boobis, Marı́a-José Gómez-Lechón, Andrea Pfeifer, José Castell

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 857 KB

english, 1999

97

Selective localisation of P450 enzymes and NADPH-P450 oxidoreductase in rat basal ganglia using anti-peptide antisera

Andrew G Riedl, Paul M Watts, Robert J Edwards, Alan R Boobis, Peter Jenner, C.David Marsden

Journal:

Year:

1996

Language:

english

File:

PDF, 319 KB

english, 1996

98

Expression and localisation of CYP2D enzymes in rat basal ganglia

Andrew G Riedl, Paul M Watts, Robert J Edwards, Timothy Schulz-Utermoehl, Alan R Boobis, Peter Jenner, C.David Marsden

Journal:

Year:

1999

Language:

english

File:

PDF, 2.16 MB

english, 1999

99

Assessing human risk to heterocyclic amines

N.J Gooderham, S Murray, A.M Lynch, M Yadollahi-Farsani, K Zhao, K Rich, A.R Boobis, D.S Davies

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 212 KB

english, 1997

100

P XI A.14 - P XI A.14 Genetic analysis of PhlP Intestinal mutations in Muta™#Mouse

Anthony M. Lynch, Nigel J. Gooderham, Alan R. Boobis

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 120 KB

english, 1997

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