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51

Binding of the antitumor drug platinum uracil blue to closed and nicked circular duplex DNAs

Bauer, William, Gonias, Steven L., Kam, Siu K., Wu, Kun C., Lippard, Stephen J.

Journal:

Year:

1978

Language:

english

File:

PDF, 2.75 MB

english, 1978

52

Reaction of human .alpha.2-macroglobulin half-molecules with plasmin as a probe of protease binding site structure

Gonias, Steven L., Pizzo, Salvatore V.

Journal:

Year:

1983

Language:

english

File:

PDF, 2.83 MB

english, 1983

53

Characterization of functional human .alpha.2-macroglobulin half-molecules isolated by limited reduction with dithiothreitol

Gonias, Steven L., Pizzo, Salvatore V.

Journal:

Year:

1983

Language:

english

File:

PDF, 5.45 MB

english, 1983

54

LDL Receptor-Related Protein 1 Regulates the Abundance of Diverse Cell-Signaling Proteins in the Plasma Membrane Proteome

Gaultier, Alban, Simon, Gabriel, Niessen, Sherry, Dix, Melissa, Takimoto, Shinako, Cravatt, Benjamin F., Gonias, Steven L.

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 1.79 MB

english, 2010

55

Reaction of nerve growth factor .gamma. and 7S nerve growth factor complex with human and murine .alpha.2-macroglobulin

Wolf, Beni B., Vasudevan, Jayanand, Gonias, Steven L.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.11 MB

english, 1993

56

.alpha.-Macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system

Enghild, Jan J., Thogersen, Ida B., Salvesen, Guy, Fey, Georg H., Figler, Nancy L., Gonias, Steven L., Pizzo, Salvatore V.

Journal:

Year:

1990

Language:

english

File:

PDF, 3.44 MB

english, 1990

57

Neurotrophin Binding to Human .alpha.2-Macroglobulin under Apparent Equilibrium Conditions

Wolf, Beni B., Gonias, Steven L.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.66 MB

english, 1994

58

uPAR Induces Expression of Transforming Growth Factor β and Interleukin-4 in Cancer Cells to Promote Tumor-Permissive Conditioning of Macrophages

Hu, Jingjing, Jo, Minji, Eastman, Boryana M., Gilder, Andrew S., Bui, Jack D., Gonias, Steven L.

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

59

Stable Antisense RNA Expression Neutralizes the Activity of Low-Density Lipoprotein Receptor-Related Protein and Promotes Urokinase Accumulation in the Medium of an Astrocytic Tumor Cell Line

HUSSAINI, ISA M., BROWN, MORRY D., WEAVER, ALISSA M., CARPENTER, JOAN, KARNS, LARRY R., VANDENBERG, SCOTT R., GONIAS, STEVEN L.

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1999

Language:

english

File:

PDF, 6.79 MB

english, 1999

60

Cleavage of Recombinant Murine Interferon-7 by Plasmin and Miniplasmin

GONIAS, STEVEN L., YOUNG, WILLIAM W., FOX, JAY W.

Journal:

Journal of Interferon Research

Year:

1989

Language:

english

File:

PDF, 5.22 MB

english, 1989

61

Cooperativity between the Ras-ERK and Rho-Rho Kinase Pathways in Urokinase-type Plasminogen Activator-stimulated Cell Migration

Jo, Minji, Thomas, Keena S., Somlyo, Avril V., Somlyo, Andrew P., Gonias, Steven L.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 213 KB

english, 2002

62

Proteomic Analysis Reveals a Role for Bcl2-associated Athanogene 3 and Major Vault Protein in Resistance to Apoptosis in Senescent Cells by Regulating ERK1/2 Activation

Pasillas, Martina P., Shields, Sarah, Reilly, Rebecca, Strnadel, Jan, Behl, Christian, Park, Robin, Yates, John R., Klemke, Richard, Gonias, Steven L., Coppinger, Judith A.

Journal:

Molecular & Cellular Proteomics

Year:

2015

Language:

english

File:

PDF, 2.89 MB

english, 2015

63

Regulation of the Composition of the Extracellular Matrix by Low Density Lipoprotein Receptor-related Protein-1

Gaultier, Alban, Salicioni, Ana Maria, Arandjelovic, Sanja, Gonias, Steven L.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 389 KB

english, 2006

64

Specificity of α 2 -Macroglobulin Covalent Cross-Linking for the Active Domain of Proteinases

PIZZO, Salvatore V., RAJAGOPALAN, Shrin, ROCHE, Paul A., FUCHS, Herbert E., FELDMAN, Steven R., GONIAS, Steven L.

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1986

Language:

english

File:

PDF, 1.13 MB

english, 1986

65

Low density lipoprotein receptor-related protein: regulation of the plasma membrane proteome

Gonias, Steven L., Wu, Lihua, Salicioni, Ana Maria

Journal:

Thrombosis and Haemostasis

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

66

Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion

Gilder, Andrew S., Jones, Karra A., Hu, Jingjing, Wang, Lei, Chen, Clark C., Carter, Bob S., Gonias, Steven L.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.22 MB

english, 2015

67

Effect of Human α-Thrombin on the Transforming Growth Factor-β1-Binding Activity of Human α 2 -Macroglobulin

Webb, Donna, LaMarre, Jonathan, Gonias, Steven

Journal:

Seminars in Thrombosis and Hemostasis

Year:

1992

Language:

english

File:

PDF, 1.18 MB

english, 1992

68

Secretion of α 2 -macroglobulin, α 2 -antiplasmin, and plasminogen activator inhibitor-1 by glioblastoma multiforme in primary organ culture

Keohane, Mary E., Hall, Scott W., VandenBerg, Scott R., Gonias, Steven L.

Journal:

Journal of Neurosurgery

Year:

1990

Language:

english

File:

PDF, 1.87 MB

english, 1990

69

Regulation of Rac1 Activation by the Low Density Lipoprotein Receptor-Related Protein

Zhong Ma, Keena S. Thomas, Donna J. Webb, Radim Moravec, Ana Maria Salicioni, Wendy M. Mars and Steven L. Gonias

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 2.45 MB

english, 2002

70

Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells

Jingjing Hu, Minji Jo, Webster K. Cavenee, Frank Furnari, Scott R. VandenBerg and Steven L. Gonias

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

71

The biochemistry of haemostasis

Gonias, Steven L., Pizzo, Salvatore V.

Journal:

Clinical and Laboratory Haematology

Year:

1986

Language:

english

File:

PDF, 1.79 MB

english, 1986

72

MP83-19 UPAR AND MTORC2: COUPLED TARGETS FOR THERAPEUTICS DEVELOPMENT IN BLADDER CANCER

Hau, Andrew, Gilder, Andrew, Hu, Jingjing, Gonias, Steven, Hansel, Donna

Journal:

The Journal of Urology

Year:

2016

Language:

english

File:

PDF, 37 KB

english, 2016

73

Growth Factor-Binding Sequence in Human α 2 -Macroglobulin Targets the Receptor-Binding Site in Transforming Growth Factor-β †

Arandjelovic, Sanja, Freed, Tiffany A., Gonias, Steven L.

Journal:

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

74

Regulation of the Urokinase Receptor (uPAR) by LDL Receptor-related Protein-1 (LRP1)

L. Gonias, Steven, Gaultier, Alban, Jo, Minji

Journal:

Current Pharmaceutical Design

Year:

2011

Language:

english

File:

PDF, 484 KB

english, 2011

75

Life-long Bleeding Diathesis: Effect of Orthotopic Liver Transplantation

Humphries, John E., Gonias, Steven L., Pizzo, Salvatore V., Williams, Michael E.

Journal:

American Journal of Clinical Pathology

Year:

1994

Language:

english

File:

PDF, 570 KB

english, 1994

76

Activated α2-Macroglobulin Reverses the Immunosuppressive Activity in Human Breast Cancer Cell-Conditioned Medium by Selectively Neutralizing Transforming Growth Factor-β in the Presence of Interleukin-2

Harthun, Nancy L., Weaver, Alissa M., Brinckerhoff, Laurence H., Deacon, Donna H., Gonias, Steven L., Slingluff, Craig L.

Journal:

Journal of Immunotherapy

Year:

1998

File:

PDF, 778 KB

1998

77

Cytokeratin 8 released by breast carcinoma cells in vitro binds plasminogen and tissue-type plasminogen activator and promotes plasminogen activation

HEMBROUGH, Todd A., KRALOVICH, Kristen R., LI, Li, GONIAS, Steven L.

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 505 KB

english, 1996

78

Characterization of the interaction between α2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions

MATHEW, Smitha, ARANDJELOVIC, Sanja, BEYER, Wayne F., GONIAS, Steven L., PIZZO, Salvatore V.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 163 KB

english, 2003

79

Activation of hepatocyte growth factor by urokinase-type plasminogen activator is ionic strength-dependent

Mars, Wendy M., Jo, Minji, Gonias, Steven L.

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 334 KB

english, 2005

80

Proteinases are isoform-specific regulators of the binding of transforming growth factor β to α 2 -macroglobulin

WEBB, Donna J., WEAVER, Alissa M., ATKINS-BRADY, Tara L., GONIAS, Steven L.

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 328 KB

english, 1996

81

mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer

Hau, Andrew M., Leivo, Mariah Z., Gilder, Andrew S., Hu, Jing-Jing, Gonias, Steven L., Hansel, Donna E.

Journal:

Cellular Signalling

Year:

2017

Language:

english

File:

PDF, 2.83 MB

english, 2017

82

Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells

Campana, Wendy M., Mantuano, Elisabetta, Azmoon, Pardis, Henry, Kenneth, Banki, Michael A., Kim, John H., Pizzo, Donald P., Gonias, Steven L.

Journal:

The FASEB Journal

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

83

Tissue-type Plasminogen Activator Regulates Macrophage Activation and Innate Immunity

Mantuano, Elisabetta, Azmoon, Pardis, Brifault, Coralie, Banki, Michael A., Gilder, Andrew S., Campana, Wendy M., Gonias, Steven L.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

84

The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains

Laudati, Emilia, Gilder, Andrew S., Lam, Michael S., Misasi, Roberta, Sorice, Maurizio, Gonias, Steven L., Mantuano, Elisabetta

Journal:

Molecular and Cellular Neuroscience

Year:

2016

Language:

english

File:

PDF, 1.25 MB

english, 2016

85

Evidence that LDL receptor-related protein 1 acts as an early injury detection receptor and activates c-Jun in Schwann cells

Flütsch, Andreas, Henry, Kenneth, Mantuano, Elisabetta, Lam, Michael S., Shibayama, Masataka, Takahashi, Kazuhisa, Gonias, Steven L., Campana, Wendy M.

Journal:

Year:

2016

Language:

english

File:

PDF, 261 KB

english, 2016

86

Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuro-inflammation

Brifault, Coralie, Gilder, Andrew S., Laudati, Emilia, Banki, Michael, Gonias, Steven L.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 6.15 MB

english, 2017

87

The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres

Gilder, Andrew S., Natali, Letizia, Van Dyk, Danielle M., Zalfa, Cristina, Banki, Michael A., Pizzo, Donald P., Wang, Huawei, Klemke, Richard L., Mantuano, Elisabetta, Gonias, Steven L.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.92 MB

english, 2018

88

Schwann cells regulate sensory neuron gene expression before and after peripheral nerve injury

Poplawski, Gunnar, Ishikawa, Tetsuhiro, Brifault, Coralie, Lee-Kubli, Corinne, Regestam, Robert, Henry, Kenneth W., Shiga, Yasuhiro, Kwon, HyoJun, Ohtori, Seiji, Gonias, Steven L., Campana, Wendy M.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.60 MB

english, 2018

89

Transcriptional regulation of LDL receptor-related protein by IFN-γ and the antagonistic activity of TGF-β1 in the RAW 264.7 macrophage-like cell line

Hussaini, Isa M., LaMarre, Jonathan, Lysiak, Jeffrey J., Karns, Larry R., VandenBerg, Scott R., Gonias, Steven L.

Journal:

Journal of Leukocyte Biology

Year:

1996

Language:

english

File:

PDF, 1.37 MB

english, 1996

90

Mammalian Target of Rapamycin Complex 2 (mTORC2) Is a Critical Determinant of Bladder Cancer Invasion

Gupta, Sounak, Hau, Andrew M., Beach, Jordan R., Harwalker, Jyoti, Mantuano, Elisabetta, Gonias, Steven L., Egelhoff, Thomas T., Hansel, Donna E., Kyprianou, Natasha

Journal:

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

91

PAI1 blocks effects of tissue-type plasminogen activator on cell-signaling and physiology mediated by the NMDA receptor

Gonias, Steven L., Banki, Michael A., Gilder, Andrew S., Azmoon, Pardis, Campana, Wendy M., Mantuano, Elisabetta

Journal:

Journal of Cell Science

Year:

2018

Language:

english

File:

PDF, 969 KB

english, 2018

92

Urokinase receptor and resistance to targeted anticancer agents

Gonias, Steven L., Hu, Jingjing

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

93

Cytokeratin 8 functions as a major plasminogen receptor in select epithelial and carcinoma cells

Gonias, Steven L

Journal:

Frontiers in Bioscience

Year:

2001

Language:

english

File:

PDF, 285 KB

english, 2001

94

Mechanisms by Which LRP1 (Low-Density Lipoprotein Receptor–Related Protein-1) Maintains Arterial Integrity

Gonias, Steven L.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2018

Language:

english

File:

PDF, 209 KB

english, 2018

95

LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing

Brifault, Coralie, Kwon, HyoJun, Campana, Wendy M., Gonias, Steven L.

Journal:

Year:

2019

File:

PDF, 3.20 MB

2019

96

LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing

Brifault, Coralie, Kwon, HyoJun, Campana, Wendy M., Gonias, Steven L.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.20 MB

english, 2019

97

Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages

Das, Lipsa, Azmoon, Pardis, Banki, Michael A., Mantuano, Elisabetta, Gonias, Steven L., Furuta, Saori

Journal:

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

98

Cytokeratin 8 functions as a major plasminogen receptor in select epithelial and carcinoma cells

Gonias, Steven, L.

Journal:

Frontiers in Bioscience

Year:

2001

File:

PDF, 285 KB

2001

99

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines

Pontecorvi, Paola, Banki, Michael A., Zampieri, Carlotta, Zalfa, Cristina, Azmoon, Pardis, Kounnas, Maria Z., Marchese, Cinzia, Gonias, Steven L., Mantuano, Elisabetta

Journal:

Journal of Neuroinflammation

Year:

2019

File:

PDF, 1.98 MB

2019

100

A soluble derivative of PrP C activates cell-signaling and regulates cell physiology through LRP1 and the NMDA Receptor

Mantuano, Elisabetta, Azmoon, Pardis, Banki, Michael A., Lam, Michael S., Sigurdson, Christina J., Gonias, Steven L.

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 1.78 MB

2020

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