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1

Synthesis and Pharmacology of Ethylphenidate Enantiomers: The Human Transesterification Metabolite of Methylphenidate and Ethanol

Patrick, Kennerly S., Williard, Robin L., VanWert, Adam L., Dowd, Justin J., Oatis,, John E., Middaugh, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

2

Neurochemical and behavioral effects of diet related perinatal folic acid restriction

Lawrence D. Middaugh, Thomas A. Grover, L. Ann Blackwell, John W. Zemp

Journal:

Pharmacology Biochemistry and Behavior

Year:

1976

Language:

english

File:

PDF, 479 KB

english, 1976

3

DAD1- and DAD2-like agonist effects on motor activity of C57 mice: Differences compared to rats

Justin P. Halberda, Lawrence D. Middaugh, Brian E. Gard, Brad P. Jackson

Journal:

Year:

1997

Language:

english

File:

PDF, 156 KB

english, 1997

4

Highly active antiretroviral therapy and human immunodeficiency virus encephalitis

Jennifer E. Cook, Somsankar Dasgupta, Lawrence D. Middaugh, Elaine C. Terry, Paul R. Gorry, Steven L. Wesselingh, William R. Tyor

Journal:

Annals of Neurology

Year:

2005

Language:

english

File:

PDF, 293 KB

english, 2005

5

Effects of d-amphetamine sulfate given to pregnant mice on activity and on catecholamines in the brains of offspring

Dr. Lawrence D. Middaugh, L. Ann Blackwell, Carroll A. Santos III, John W. Zemp

Journal:

Developmental Psychobiology

Year:

1974

Language:

english

File:

PDF, 640 KB

english, 1974

6

Effects of phenobarbital given to pregnant mice on behavior of mature offspring

Dr. Lawrence D. Middaugh, Carroll A. Santos III, John W. Zemp

Journal:

Developmental Psychobiology

Year:

1975

Language:

english

File:

PDF, 547 KB

english, 1975

7

Long-term intracranial cannula stabilization in mice with light cured resin composites

Chad H Groseclose, Robert A Draughn, William R Tyor, Floyd R Sallee, Lawrence D Middaugh

Journal:

Journal of Neuroscience Methods

Year:

1998

Language:

english

File:

PDF, 394 KB

english, 1998

8

The discrimination and durability of an ethanol cue in young and mid-aged female mice

Chad H. Groseclose, Lawrence D. Middaugh

Journal:

Year:

1997

Language:

english

File:

PDF, 758 KB

english, 1997

9

Ethanol Consumption by C57BL/6 Mice: Influence of Gender and Procedural Variables

Lawrence D Middaugh, Brian M Kelley, Angela-Leigh E Bandy, Kimberly K McGroarty

Journal:

Year:

1999

Language:

english

File:

PDF, 203 KB

english, 1999

10

Operant Ethanol Reward in C57BL/6 Mice: Influence of Gender and Procedural Variables

Lawrence D Middaugh, Brian M Kelley

Journal:

Year:

1999

Language:

english

File:

PDF, 202 KB

english, 1999

11

Tiagabine reduces ethanol reward in C57BL/6 mice under acute and chronic administration regimens

Shaun A. Nguyen, Christopher P. Deleon, Robert J. Malcolm, Lawrence D. Middaugh

Journal:

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

12

Topiramate reduces ethanol consumption by C57BL/6 mice

Shaun A. Nguyen, Robert Malcolm, Lawrence D. Middaugh

Journal:

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

13

Discriminative properties of phencyclidine in mice: generalization to ketamine and monohydroxy metabolites

Lawrence D. Middaugh, Jean P. Favara, William O. Boggan, Amy J. Stringer

Journal:

Psychopharmacology

Year:

1988

Language:

english

File:

PDF, 400 KB

english, 1988

14

Prenatal maternal phenobarbital increases reactivity and retards habituation of mature offspring to environmental stimuli

Lawrence D. Middaugh, Larry W. Simpson, Thomas N. Thomas, John W. Zemp

Journal:

Psychopharmacology

Year:

1981

Language:

english

File:

PDF, 443 KB

english, 1981

15

Repeated cycles of chronic intermittent ethanol exposure in mice increases voluntary ethanol drinking and ethanol concentrations in the nucleus accumbens

William C. Griffin, Marcelo F. Lopez, Amy B. Yanke, Lawrence D. Middaugh, Howard C. Becker

Journal:

Psychopharmacology

Year:

2009

Language:

english

File:

PDF, 414 KB

english, 2009

16

Naltrexone effects on ethanol consumption and response to ethanol conditioned cues in C57BL/6 mice

Lawrence D. Middaugh, Angela-Leigh E. Bandy

Journal:

Psychopharmacology

Year:

2000

Language:

english

File:

PDF, 92 KB

english, 2000

17

Gas chromatographic—mass spectrometric determination of plasma and brain cocaine in mice

Kennerly S. Patrick, William O. Boggan, Scott R. Miller, Lawrence D. Middaugh

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 572 KB

english, 1993

18

The nigrostriatal dopamine system of aging GFRα-1 heterozygous mice: neurochemistry, morphology and behavior

Vandana Zaman, Heather A. Boger, Ann-Charlotte Granholm, Baerbel Rohrer, Alfred Moore, Mona Buhusi, Greg A. Gerhardt, Barry J. Hoffer, Lawrence D. Middaugh

Journal:

European Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 1.69 MB

english, 2008

19

A Study Examining Intravenous Ethanol-Conditioned Place Preference in C57BL/6J Mice

Brian M. Kelley, Angela-Leigh E. Bandy, Lawrence D. Middaugh

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1997

Language:

english

File:

PDF, 826 KB

english, 1997

20

Naltrexone Effects on Ethanol Reward and Discrimination in C57BL/6 Mice

Lawrence D. Middaugh, Brian M. Kelley, Eduardo R. Cuison Jr., Chad H. Groseclose

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1999

Language:

english

File:

PDF, 993 KB

english, 1999

21

Ethanol Consumption and Place-Preference Conditioning in the Alcohol-Preferring C57BL/6 Mouse: Relationship with Motor Activity Patterns

Christine Nocjar, Lawrence D. Middaugh, Michael Tavernetti

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1999

Language:

english

File:

PDF, 1.05 MB

english, 1999

22

Ethanol Reinforcement in Nondeprived Mice: Effects of Abstinence and Naltrexone

Lawrence D. Middaugh, Allison M. Lee, Angela-Leigh E. Bandy

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

23

Impact of Sex: Determination of Alcohol Neuroadaptation and Reinforcement

Kristine M. Wiren, Joel G. Hashimoto, Paul E. Alele, Leslie L. Devaud, Kimber L. Price, Lawrence D. Middaugh, Kathleen A. Grant, Deborah A. Finn

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2006

Language:

english

File:

PDF, 139 KB

english, 2006

24

Development of an Alcohol Deprivation and Escalation Effect in C57BL/6J Mice

Roberto I. Melendez, Lawrence D. Middaugh, Peter W. Kalivas

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

25

Prenatal LPS increases Inflammation in the Substantia Nigra of Gdnf Heterozygous Mice

Ann-Charlotte Granholm, Vandana Zaman, Jennifer Godbee, Michael Smith, Riad Ramadan, Claudia Umphlet, Patrick Randall, Narayan R. Bhat, Baerbel Rohrer, Lawrence D. Middaugh, Heather A. Boger

Journal:

Brain Pathology

Year:

2011

Language:

english

File:

PDF, 3.06 MB

english, 2011

26

Chronic Ethanol Consumption by C57BL/6 Mice Promotes Tolerance to Its Interoceptive Cues and Increases Extracellular Dopamine, an Effect Blocked by Naltrexone

Lawrence D. Middaugh, Karen K. Szumlinski, Yancy Van Patten, Angela-Leigh Bandy Marlowe, Peter W. Kalivas

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2003

Language:

english

File:

PDF, 214 KB

english, 2003

27

Differential Neurosensitivity to the Discriminative Stimulus Properties of Ethanol in C57BL/6J and C3H/He Mice

Howard C. Becker, Alicia M. Crissman, Shannon Studders, Brian M. Kelley, Lawrence D. Middaugh

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2004

Language:

english

File:

PDF, 138 KB

english, 2004

28

The Dopamine D1 Antagonist Reduces Ethanol Reward for C57BL/6 Mice

Kimber L. Price, Lawrence D. Middaugh

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

29

Evidence for a Relationship between Group 1 mGluR Hypofunction and Increased Cocaine and Ethanol Sensitivity in Homer2 Null Mutant Mice

KAREN K. SZUMLINSKI, SHIGENOBU TODA, LAWRENCE D. MIDDAUGH, PAUL F. WORLEY, PETER W. KALIVAS

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 114 KB

2003

30

The severe combined immunodeficient (SCID) mouse model of human immunodeficiency virus encephalitis: Deficits in cognitive function

William C. Griffin, Lawrence D. Middaugh, Jennifer E. Cook, William R. Tyor

Journal:

Journal of NeuroVirology

Year:

2004

Language:

english

File:

PDF, 1.10 MB

english, 2004

31

Prenatal ethanol weakens the efficacy of reinforcers for adult mice

G. David Gentry, Lawrence D. Middaugh

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

1988

Language:

english

File:

PDF, 948 KB

english, 1988

32

Phenobarbital during pregnancy alters operant behavior of offspring in C57BL/6J mice

Lawrence D. Middaugh, Carroll A. Santos III, John W. Zemp

Journal:

Pharmacology Biochemistry and Behavior

Year:

1975

Language:

english

File:

PDF, 317 KB

english, 1975

33

Effects of methadone on activity and on brain monoamines in two strains of mice

Lawrence D. Middaugh, John W. Zemp

Journal:

Pharmacology Biochemistry and Behavior

Year:

1976

Language:

english

File:

PDF, 379 KB

english, 1976

34

Effects of naloxone on ethanol induced alterations of locomotor activity in C57BL/6 mice

Lawrence D. Middaugh, Elizabeth Read, William O. Boggan

Journal:

Pharmacology Biochemistry and Behavior

Year:

1978

Language:

english

File:

PDF, 371 KB

english, 1978

35

Effects of methadone on behavior maintained by fixed ratio reinforcement schedules

Lawrence D. Middaugh, Carroll A. Santos III

Journal:

Pharmacology Biochemistry and Behavior

Year:

1978

Language:

english

File:

PDF, 568 KB

english, 1978

36

Brain concentrations of phenobarbital and behavioral activation or depression

Lawrence D. Middaugh, L. Ann Blackwell, William O. Boggan, John W. Zemp

Journal:

Pharmacology Biochemistry and Behavior

Year:

1981

Language:

english

File:

PDF, 597 KB

english, 1981

37

Effects of caffeine and L-phenylisopropyladenosine on locomotor activity of mice

Neil S. Buckholtz, Lawrence D. Middaugh

Journal:

Pharmacology Biochemistry and Behavior

Year:

1987

Language:

english

File:

PDF, 597 KB

english, 1987

38

Doubtful role for phenycyclidine metabolites in PCP enhancement of QNB binding

William O. Boggan, Lawrence D. Middaugh

Journal:

Pharmacology Biochemistry and Behavior

Year:

1987

Language:

english

File:

PDF, 572 KB

english, 1987

39

Effect of phencyclidine and two monohydroxy metabolites on 3H QNB binding in vivo in rats

William O. Boggan, Amy J. Stringer, Karla Faught, Lawrence D. Middaugh

Journal:

Pharmacology Biochemistry and Behavior

Year:

1987

Language:

english

File:

PDF, 226 KB

english, 1987

40

Parametric studies on phencyclidine enhancement of 3H quinuclidinyl Benzilate accumulation in vitro

William O. Boggan, Karla Faught, Scott Boyd, Lawrence D. Middaugh

Journal:

Pharmacology Biochemistry and Behavior

Year:

1988

Language:

english

File:

PDF, 396 KB

english, 1988

41

Ethanol stimulation after chronic exposure in C57 mice

Lawrence D. Middaugh, Jean P. Favara, William O. Boggan

Journal:

Pharmacology Biochemistry and Behavior

Year:

1989

Language:

english

File:

PDF, 426 KB

english, 1989

42

Effects of Ro 15-4513 on ethanol discrimination in C57BL/6 mice

Lawrence D. Middaugh, Kexin Bao, Howard C. Becker, Stephanie Sergent Daniel

Journal:

Pharmacology Biochemistry and Behavior

Year:

1991

Language:

english

File:

PDF, 451 KB

english, 1991

43

Comparative effects of ethanol on motor activity and operant behavior

Lawrence D. Middaugh, Kexin Bao, Cindy L. Shepherd

Journal:

Pharmacology Biochemistry and Behavior

Year:

1992

Language:

english

File:

PDF, 457 KB

english, 1992

44

Prenatal ethanol exposure in C57 mice: Effects on pregnancy and offspring development

Lawrence D. Middaugh, Carrie L. Randall, Jean P. Favara

Journal:

Neurotoxicology and Teratology

Year:

1988

Language:

english

File:

PDF, 641 KB

english, 1988

45

Developmental neurotoxicity of anticonvulsants: Human and animal evidence on phenytoin

Jane Adams, Charles V. Vorhees, Lawrence D. Middaugh

Journal:

Neurotoxicology and Teratology

Year:

1990

Language:

english

File:

PDF, 1.29 MB

english, 1990

46

Prenatal ethanol effects on reward efficacy for adult mice are gestation stage specific

Lawrence D. Middaugh, G.David Gentry

Journal:

Neurotoxicology and Teratology

Year:

1992

Language:

english

File:

PDF, 618 KB

english, 1992

47

Prenatal ethanol effects and dopamine systems of adult C57 male mice

Lawrence D. Middaugh, William O. Boggan, Cindy L. Shepherd

Journal:

Neurotoxicology and Teratology

Year:

1994

Language:

english

File:

PDF, 587 KB

english, 1994

48

Effects of prenatal maternal ethanol on male offspring progressive-ratio performance and response to amphetamine

G.David Gentry, Cindy J. Merritt, Lawrence D. Middaugh

Journal:

Neurotoxicology and Teratology

Year:

1995

Language:

english

File:

PDF, 611 KB

english, 1995

49

Effects of prenatal ethanol exposure on dopamine systems in C57BL/6J mice

William O. Boggan, Weidong Xu, Cindy L. Shepherd, Lawrence D. Middaugh

Journal:

Neurotoxicology and Teratology

Year:

1996

Language:

english

File:

PDF, 913 KB

english, 1996

50

Cognitive deficits in a murine model of the eosinophilia-myalgia syndrome: A preliminary report

Lawrence D. Middaugh, Rachel Nussbaum, Anna Ludwicka, Marcy B. Bolster, Richard M. Silver

Journal:

Neurotoxicology and Teratology

Year:

1996

Language:

english

File:

PDF, 832 KB

english, 1996

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