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1

Biochemical properties and regulation of cathepsin K activity

Fabien Lecaille, Dieter Brömme, Gilles Lalmanach

Journal:

Year:

2008

Language:

english

File:

PDF, 466 KB

english, 2008

2

Cathepsin K inhibitors for osteoporosis and potential off-target effects

Brömme, Dieter, Lecaille, Fabien

Journal:

Expert Opinion on Investigational Drugs

Year:

2009

Language:

english

File:

PDF, 2.18 MB

english, 2009

3

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Galibert, Matthieu, Wartenberg, Mylène, Lecaille, Fabien, Saidi, Ahlame, Mavel, Sylvie, Joulin-Giet, Alix, Korkmaz, Brice, Brömme, Dieter, Aucagne, Vincent, Delmas, Agnès F., Lalmanach, Gilles

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

4

Synthesis of a Biologically Active Triazole-Containing Analogue of Cystatin A Through Successive Peptidomimetic Alkyne–Azide Ligations

Dr. Ibai E. Valverde, Dr. Fabien Lecaille, Prof. Dr. Gilles Lalmanach, Dr. Vincent Aucagne, Dr. Agnès F. Delmas

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 1004 KB

english, 2012

5

Human and Parasitic Papain-Like Cysteine Proteases: Their Role in Physiology and Pathology and Recent Developments in Inhibitor Design

Fabien Lecaille, Jadwiga Kaleta, Dieter Broemme

Journal:

Year:

2003

File:

PDF, 55 KB

2003

6

Subsite specificity of trypanosomal cathepsin L-like cysteine proteases : Probing the S2 pocket with phenylalanine-derived amino acids

Fabien Lecaille, Edith Authié, Thierry Moreau, Carole Serveau, Francis Gauthier, Gilles Lalmanach

Journal:

Year:

2001

Language:

english

File:

PDF, 652 KB

english, 2001

7

Cysteine Cathepsins: Markers and Therapy Targets in Lung Disorders

Mariana Kasabova, Ahlame Saidi, Clément Naudin, Juliette Sage, Fabien Lecaille, Gilles Lalmanach

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2011

Language:

english

File:

PDF, 273 KB

english, 2011

8

The S2 subsites of cathepsins K and L and their contribution to collagen degradation

Fabien Lecaille, Shafinaz Chowdhury, Enrico Purisima, Dieter Brömme, Gilles Lalmanach

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 391 KB

english, 2007

9

Synthesis of a Biologically Active Triazole-Containing Analogue of Cystatin A Through Successive Peptidomimetic Alkyne–Azide Ligations

Dr. Ibai E. Valverde, Dr. Fabien Lecaille, Prof. Dr. Gilles Lalmanach, Dr. Vincent Aucagne, Dr. Agnès F. Delmas

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 997 KB

english, 2012

10

Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide

Virginie Hervé-Grépinet, Florian Veillard, Emmanuel Godat, Nathalie Heuzé-Vourc’h, Fabien Lecaille, Gilles Lalmanach

Journal:

Year:

2008

Language:

english

File:

PDF, 400 KB

english, 2008

11

Modulation of hypotensive effects of kinins by cathepsin K

Fabien Lecaille, Christophe Vandier, Emmanuel Godat, Virginie Hervé-Grépinet, Dieter Brömme, Gilles Lalmanach

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 732 KB

english, 2007

12

Lung cysteine cathepsins: Intruders or unorthodox contributors to the kallikrein–kinin system?

Florian Veillard, Fabien Lecaille, Gilles Lalmanach

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

13

Kininogens: More than cysteine protease inhibitors and kinin precursors

Gilles Lalmanach, Clément Naudin, Fabien Lecaille, Hans Fritz

Journal:

Year:

2010

Language:

english

File:

PDF, 349 KB

english, 2010

14

Reversible inhibition of cathepsin L-like proteases by 4-mer pseudopeptides

Fabien Lecaille, Joël Cotton, James H McKerrow, Michèle Ferrer-Di Martino, Emmanuelle Boll-Bataillé, Francis Gauthier, Gilles Lalmanach

Journal:

Year:

2001

Language:

english

File:

PDF, 166 KB

english, 2001

15

Revisiting the S2 specificity of papain by structural analogs of Phe

Fabien Lecaille, Carole Serveau, Francis Gauthier, Gilles Lalmanach

Journal:

Year:

1999

Language:

english

File:

PDF, 141 KB

english, 1999

16

Cathepsin K: a cysteine protease with unique kinin-degrading properties

GODAT, Emmanuel, LECAILLE, Fabien, DESMAZES, Claire, DUCHÊNE, Sophie, WEIDAUER, Enrico, SAFTIG, Paul, BRÖMME, Dieter, VANDIER, Christophe, LALMANACH, Gilles

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

17

Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor

Kryza, Thomas, Lalmanach, Gilles, Lavergne, Marion, Lecaille, Fabien, Reverdiau, Pascale, Courty, Yves, Heuzé-Vourc’h, Nathalie

Journal:

Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 728 KB

english, 2013

18

Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties

Lecaille, Fabien, Naudin, Clément, Sage, Juliette, Joulin-Giet, Alix, Courty, Agnès, Andrault, Pierre-Marie, Veldhuizen, Ruud A.W., Possmayer, Fred, Lalmanach, Gilles

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

19

Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis

Sage, Juliette, De Quéral, Delphine, Leblanc-Noblesse, Emmanuelle, Kurfurst, Robin, Schnebert, Sylvianne, Perrier, Eric, Nizard, Carine, Lalmanach, Gilles, Lecaille, Fabien

Journal:

Year:

2014

Language:

english

File:

PDF, 666 KB

english, 2014

20

The Role of Basic Amino Acid Surface Clusters on the Collagenase Activity of Cathepsin K

Nallaseth, Ferez S., Lecaille, Fabien, Li, Zhenqiang, Brömme, Dieter

Journal:

Year:

2013

Language:

english

File:

PDF, 349 KB

english, 2013

21

Inhibition of a Cathepsin L-Like Cysteine Protease by a Chimeric Propeptide-Derived Inhibitor †

Godat, Emmanuel, Chowdhury, Shafinaz, Lecaille, Fabien, Belghazi, Maya, Purisima, Enrico O., Lalmanach, Gilles

Journal:

Year:

2005

Language:

english

File:

PDF, 324 KB

english, 2005

22

Human and Parasitic Papain-Like Cysteine Proteases: Their Role in Physiology and Pathology and Recent Developments in Inhibitor Design

Lecaille, Fabien, Kaleta, Jadwiga, Brömme, Dieter

Journal:

Chemical Reviews

Year:

2002

Language:

english

File:

PDF, 1.07 MB

english, 2002

23

Selective Inhibition of the Collagenolytic Activity of Human Cathepsin K by Altering Its S2 Subsite Specificity †

Lecaille, Fabien, Choe, Youngchool, Brandt, Wolfgang, Li, Zhenqiang, Craik, Charles S., Brömme, Dieter

Journal:

Year:

2002

Language:

english

File:

PDF, 185 KB

english, 2002

24

Human cystatin C: A new biomarker of idiopathic pulmonary fibrosis?

Kasabova, Mariana, Joulin-Giet, Alix, Lecaille, Fabien, Saidi, Ahlame, Marchand-Adam, Sylvain, Lalmanach, Gilles

Journal:

PROTEOMICS - Clinical Applications

Year:

2014

Language:

english

File:

PDF, 688 KB

english, 2014

25

Regulation of TGF-β1-driven Differentiation of Human Lung Fibroblasts

Kasabova, Mariana, Joulin-Giet, Alix, Lecaille, Fabien, Gilmore, Brendan F., Marchand-Adam, Sylvain, Saidi, Ahlame, Lalmanach, Gilles

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.89 MB

english, 2014

26

Active site labeling of cysteine cathepsins by a straightforward diazomethylketone probe derived from the N-terminus of human cystatin C

Garenne, Thibaut, Saidi, Ahlame, Gilmore, Brendan F., Niemiec, Elżbieta, Roy, Vincent, Agrofoglio, Luigi A., Kasabova, Mariana, Lecaille, Fabien, Lalmanach, Gilles

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 537 KB

english, 2015

27

Cysteine cathepsins and caspases in silicosis

Lalmanach, Gilles, Diot, Elisabeth, Godat, Emmanuel, Lecaille, Fabien, Hervé-Grépinet, Virginie

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 198 KB

english, 2006

28

Cysteine cathepsins and cystatins: from ancillary tasks to prominent status in lung diseases

Lalmanach, Gilles, Saidi, Ahlame, Marchand-Adam, Sylvain, Lecaille, Fabien, Kasabova, Mariana

Journal:

Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

29

Regulation of cathepsin K activity by hydrogen peroxide

Godat, Emmanuel, Hervé-Grépinet, Virginie, Veillard, Florian, Lecaille, Fabien, Belghazi, Maya, Brömme, Dieter, Lalmanach, Gilles

Journal:

Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 91 KB

english, 2008

30

Labelling of four distinct trophozoite falcipains of Plasmodium falciparum by a cystatin-derived probe

Florent, Isabelle, Lecaille, Fabien, Montagne, Jean-Jacques, Gauthier, Francis, Schrével, Joseph, Lalmanach, Gilles

Journal:

Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 157 KB

english, 2005

31

Degradation of apolipoprotein B-100 by lysosomal cysteine cathepsins

Linke, Martin, Gordon, Ronald E., Brillard, Michèle, Lecaille, Fabien, Lalmanach, Gilles, Brömme, Dieter

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 213 KB

english, 2006

32

Antimicrobial proteins and peptides in human lung diseases: A friend and foe partnership with host proteases

Lecaille, Fabien, Lalmanach, Gilles, Andrault, Pierre-Marie

Journal:

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

33

Congopain from Trypanosoma congolense: Drug Target and Vaccine Candidate

Lalmanach, Gilles, Boulangé, Alain, Serveau, Carole, Lecaille, Fabien, Scharfstein, Julio, Gauthier, Francis, Authié, Edith

Journal:

Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 139 KB

english, 2002

34

Straightforward synthesis of 2,4,6-trisubstituted 1,3,5-triazine compounds targeting cysteine cathepsins K and S

Plebanek, Elżbieta, Chevrier, Florian, Roy, Vincent, Garenne, Thibaut, Lecaille, Fabien, Warszycki, Dawid, Bojarski, Andrzej J., Lalmanach, Gilles, Agrofoglio, Luigi A.

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 829 KB

english, 2016

35

Probing cathepsin K activity with a selective substrate spanning its active site

LECAILLE, Fabien, WEIDAUER, Enrico, JULIANO, Maria A., BRÖMME, Dieter, LALMANACH, Gilles

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

36

Eimeripain, a Cathepsin B-Like Cysteine Protease, Expressed throughout Sporulation of the Apicomplexan Parasite Eimeria tenella

Rieux, Anaïs, Gras, Simon, Lecaille, Fabien, Niepceron, Alisson, Katrib, Marilyn, Smith, Nicholas C., Lalmanach, Gilles, Brossier, Fabien, Parkinson, John

Journal:

Year:

2012

Language:

english

File:

PDF, 2.11 MB

english, 2012

37

Cleavage of Nidogen-1 by Cathepsin S Impairs Its Binding to Basement Membrane Partners

Sage, Juliette, Leblanc-Noblesse, Emmanuelle, Nizard, Carine, Sasaki, Takako, Schnebert, Sylvianne, Perrier, Eric, Kurfurst, Robin, Brömme, Dieter, Lalmanach, Gilles, Lecaille, Fabien, Rodrigues-Lima,

Journal:

Year:

2012

Language:

english

File:

PDF, 2.06 MB

english, 2012

38

The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity

Bailleul, Geoffrey, Kravtzoff, Amanda, Joulin-Giet, Alix, Lecaille, Fabien, Labas, Valérie, Meudal, Hervé, Loth, Karine, Teixeira-Gomes, Ana-Paula, Gilbert, Florence B., Coquet, Laurent, Jouenne, Thie

Journal:

Year:

2016

Language:

english

File:

PDF, 3.36 MB

english, 2016

39

Selective inhibition of human cathepsin S by 2,4,6-trisubstituted 1,3,5-triazine analogs

Tber, Zahira, Wartenberg, Mylène, Jacques, Jean-Eddy, Roy, Vincent, Lecaille, Fabien, Warszycki, Dawid, Bojarski, Andrzej J., Lalmanach, Gilles, Agrofoglio, Luigi A.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.08 MB

english, 2018

40

Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

Saidi, Ahlame, Kasabova, Mariana, Vanderlynden, Lise, Wartenberg, Mylène, Kara-Ali, Ghania Hounana, Marc, Daniel, Lecaille, Fabien, Lalmanach, Gilles

Journal:

Scientific Reports

Year:

2019

File:

PDF, 2.45 MB

2019

41

Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

Lecaille, Fabien, Chazeirat, Thibault, Bojarski, Krzysztof K., Renault, Justine, Saidi, Ahlame, Prasad, V. Gangadhara N.V., Samsonov, Sergey, Lalmanach, Gilles

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2019

Language:

english

File:

PDF, 12.18 MB

english, 2019

42

Oxidation of cathepsin S by major chemicals of cigarette smoke

Wartenberg, MylÃ¨ne, Andrault, Pierre-Marie, Saidi, Ahlame, Bigot, Paul, Nadal-Desbarats, Lydie, Lecaille, Fabien, Lalmanach, Gilles

Journal:

Free Radical Biology and Medicine

Year:

2020

Language:

english

File:

PDF, 2.52 MB

english, 2020

43

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Lalmanach, Gilles, Saidi, Ahlame, Bigot, Paul, Chazeirat, Thibault, Lecaille, Fabien, Wartenberg, MylÃ¨ne

Journal:

International Journal of Molecular Sciences

Year:

2020

Language:

english

File:

PDF, 740 KB

english, 2020

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