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1

Magnitude of Behavioral Deficits Varies with Job-Related Chlorpyrifos Exposure Levels among Egyptian Pesticide Workers

Kent Anger, W., Farahat, Fayssal M., Lein, Pamela J., Lasarev, Michael R., Olson, James R., Farahat, Taghreed M., Rohlman, Diane S.

Journal:

NeuroToxicology

Year:

2020

Language:

english

File:

PDF, 4.62 MB

english, 2020

2

DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders?

Keil, Kimberly P., Lein, Pamela J.

Journal:

Environmental Epigenetics

Year:

2016

Language:

english

File:

PDF, 237 KB

english, 2016

3

Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance

Chapman, Christopher A. R., Wang, Ling, Chen, Hao, Garrison, Joshua, Lein, Pamela J., Seker, Erkin

Journal:

Advanced Functional Materials

Year:

2017

Language:

english

File:

PDF, 19.66 MB

english, 2017

4

Developmental social communication deficits in the Shank3 rat model of phelan-mcdermid syndrome and autism spectrum disorder

Berg, Elizabeth L., Copping, Nycole A., Rivera, Josef K., Pride, Michael C., Careaga, Milo, Bauman, Melissa D., Berman, Robert F., Lein, Pamela J., Harony-Nicolas, Hala, Buxbaum, Joseph D., Ellegood,

Journal:

Autism Research

Year:

2018

Language:

english

File:

PDF, 635 KB

english, 2018

5

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Fritsche, Ellen, Grandjean, Philippe, Crofton, Kevin M., Aschner, Michael, Goldberg, Alan, Heinonen, Tuula, Hessel, Ellen V.S., Hogberg, Helena, Bennekou, Susanne Hougaard, Lein, Pamela J., Leist, Mar

Journal:

Toxicology and Applied Pharmacology

Year:

2018

Language:

english

File:

PDF, 670 KB

english, 2018

6

Identification of Psychoplastogenic N , N -Dimethylaminoisotryptamine (isoDMT) Analogues through StructureâActivity Relationship Studies

Dunlap, Lee E., Azinfar, Arya, Ly, Calvin, Cameron, Lindsay P., Viswanathan, Jayashri, Tombari, Robert J., Myers-Turnbull, Douglas, Taylor, Jack C., Grodzki, Ana Cristina, Lein, Pamela J., Kokel, Davi

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.58 MB

2020

7

Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform

ColÃ³n-RodrÃguez, Alexandra, Uribe-Salazar, JosÃ© M., Weyenberg, KaeChandra B., Sriram, Aditya, Quezada, Alejandra, Kaya, Gulhan, Jao, Emily, Radke, Brittany, Lein, Pamela J., Dennis, Megan Y.

Journal:

Frontiers in Cell and Developmental Biology

Year:

2020

File:

PDF, 2.38 MB

2020

8

Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity

Xin Guo, Yin Lin, Craig Horbinski, Karen M. Drahushuk, In-Jung Kim, Paul L. Kaplan, Pamela Lein, Tongwen Wang, Dennis Higgins

Journal:

Developmental Neurobiology

Year:

2001

Language:

english

File:

PDF, 199 KB

english, 2001

9

Bone morphogenetic proteins regulate ionotropic glutamate receptors in human retina

Wen Shen, Sarah Finnegan, Pamela Lein, Susan Sullivan, Malcolm Slaughter, Dennis Higgins

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 652 KB

english, 2004

10

Nucleic acid binding agents exert local toxic effects on neurites via a non-nuclear mechanism

Sokhon Pin, Huiling Chen, Pamela J. Lein, Michael M. Wang

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 625 KB

english, 2006

11

Rit signaling contributes to interferon-γ-induced dendritic retraction via p38 mitogen-activated protein kinase activation

Douglas A. Andres, Geng-Xian Shi, Donald Bruun, Chris Barnhart, Pamela J. Lein

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 565 KB

english, 2008

12

Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation

Woo-Yang Kim, Eugene A. Gonsiorek, Chris Barnhart, Monika A. Davare, Abby J. Engebose, Holly Lauridsen, Donald Bruun, Adam Lesiak, Gary Wayman, Robert Bucelli, Dennis Higgins, Pamela J. Lein

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 641 KB

english, 2009

13

Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures

Emun Abdu, Donald A. Bruun, Dongren Yang, Jun Yang, Bora Inceoglu, Bruce D. Hammock, Nabil J. Alkayed, Pamela J. Lein

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 524 KB

english, 2011

14

Noncholinesterase Mechanisms of Chlorpyrifos Neurotoxicity: Altered Phosphorylation of Ca2+/cAMP Response Element Binding Protein in Cultured Neurons

Rosemary A. Schuh, Pamela J. Lein, Rondell A. Beckles, David A. Jett

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 249 KB

english, 2002

15

Coordinated services for children’s mental health: A process evaluation

Rosemary Ellmer, Laura Lein, Pamela Hormuth

Journal:

The Journal of Behavioral Health Services and Research

Year:

1995

Language:

english

File:

PDF, 949 KB

english, 1995

16

Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals

Hui-Ling Chen, Pamela J. Lein, Jia-Yi Wang, Don Gash, Barry J. Hoffer, Yung-Hsiao Chiang

Journal:

Year:

2003

Language:

english

File:

PDF, 415 KB

english, 2003

17

Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity

Isaac N. Pessah, Gennady Cherednichenko, Pamela J. Lein

Journal:

Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

18

Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures

Angela S. Howard, Robert Bucelli, David A. Jett, Donald Bruun, Dongren Yang, Pamela J. Lein

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 1.99 MB

english, 2005

19

Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase

Dongren Yang, Angela Howard, Donald Bruun, Mispa Ajua-Alemanj, Cecile Pickart, Pamela J. Lein

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 706 KB

english, 2008

20

Spatiotemporal pattern of neuronal injury induced by DFP in rats: A model for delayed neuronal cell death following acute OP intoxication

Yonggang Li, Pamela J. Lein, Cuimei Liu, Donald A. Bruun, Teclemichael Tewolde, Gregory Ford, Byron D. Ford

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

21

Neuregulin-1 is neuroprotective in a rat model of organophosphate-induced delayed neuronal injury

Yonggang Li, Pamela J. Lein, Cuimei Liu, Donald A. Bruun, Cecilia Giulivi, Gregory D. Ford, Teclemichael Tewolde, Catherine Ross-Inta, Byron D. Ford

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.52 MB

english, 2012

22

Pharmacokinetics and pharmacodynamics of chlorpyrifos in adult male Long-Evans rats following repeated subcutaneous exposure to chlorpyrifos

Corie A. Ellison, Jordan Ned Smith, Pamela J. Lein, James R. Olson

Journal:

Year:

2011

Language:

english

File:

PDF, 369 KB

english, 2011

23

Manganese induces neurite outgrowth in PC12 cells via upregulation of αv integrins

Pamela Lein, Patrick J. Gallagher, Jeffrey Amodeo, Heather Howie, Jerome A. Roth

Journal:

Year:

2000

Language:

english

File:

PDF, 1.04 MB

english, 2000

24

Effect of leukemia inhibitory factor (LIF) on the morphology and survival of cultured hippocampal neurons and glial cells

Reto A Gadient, Pamela Lein, Dennis Higgins, Paul H Patterson

Journal:

Year:

1998

Language:

english

File:

PDF, 139 KB

english, 1998

25

Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor

Angela S Howard, Richard Fitzpatrick, Isaac Pessah, Paul Kostyniak, Pamela J Lein

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 559 KB

english, 2003

26

Leukemia inhibitory factor and ciliary neurotrophic factor regulate dendritic growth in cultures of rat sympathetic neurons

Xin Guo, Johnna Metzler-Northrup, Pamela Lein, David Rueger, Dennis Higgins

Journal:

Developmental Brain Research

Year:

1997

Language:

english

File:

PDF, 1022 KB

english, 1997

27

Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons

Hiroko N Beck, Karen Drahushuk, David B Jacoby, Dennis Higgins, Pamela J Lein

Journal:

BMC Neuroscience

Year:

2001

Language:

english

File:

PDF, 1.07 MB

english, 2001

28

Laminin and a basement membrane extract have different effects on axonal and dendritic outgrowth from embryonic rat sympathetic neurons in vitro

Pamela J. Lein, Dennis Higgins

Journal:

Developmental Biology

Year:

1989

Language:

english

File:

PDF, 10.45 MB

english, 1989

29

THE EFFECTS OF EXTRACELLULAR MATRIX AND OSTEOGENIC PROTEIN-1 ON THE MORPHOLOGICAL DIFFERENTIATION OF RAT SYMPATHETIC NEURONS

PAMELA LEIN, XIN GUO, ANN MARIE HEDGES, DAVID RUEGER, MARY JOHNSON, DENNIS HIGGINS

Journal:

International Journal of Developmental Neuroscience

Year:

1996

Language:

english

File:

PDF, 2.32 MB

english, 1996

30

Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons

Pamela Lein, Mary Johnson, Xin Guo, David Rueger, Dennis Higgins

Journal:

Year:

1995

Language:

english

File:

PDF, 3.05 MB

english, 1995

31

Immunologic and neurodevelopmental susceptibilities of autism

Isaac N. Pessah, Richard F. Seegal, Pamela J. Lein, Janine LaSalle, Benjamin K. Yee, Judy Van De Water, Robert F. Berman

Journal:

NeuroToxicology

Year:

2008

Language:

english

File:

PDF, 352 KB

english, 2008

32

Animal models of autism spectrum disorders: Information for neurotoxicologists

Alycia K. Halladay, David Amaral, Michael Aschner, Valerie J. Bolivar, Aaron Bowman, Emanuel DiCicco-Bloom, Susan L. Hyman, Flavio Keller, Pamela Lein, Isaac Pessah, Linda Restifo, David W. Threadgill

Journal:

NeuroToxicology

Year:

2009

Language:

english

File:

PDF, 213 KB

english, 2009

33

Chlorpyrifos exposures in Egyptian cotton field workers

Fayssal M. Farahat, Richard A. Fenske, James R. Olson, Kit Galvin, Matthew R. Bonner, Diane S. Rohlman, Taghreed M. Farahat, Pamela J. Lein, W. Kent Anger

Journal:

NeuroToxicology

Year:

2010

Language:

english

File:

PDF, 385 KB

english, 2010

34

Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure

Diane S. Rohlman, W. Kent Anger, Pamela J. Lein

Journal:

NeuroToxicology

Year:

2011

Language:

english

File:

PDF, 173 KB

english, 2011

35

A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation

Christopher N. Banks, Pamela J. Lein

Journal:

NeuroToxicology

Year:

2012

Language:

english

File:

PDF, 518 KB

english, 2012

36

Emerging concepts in neurotoxicology: Models, mechanisms and modifying factors

Journal:

NeuroToxicology

Year:

2012

Language:

english

File:

PDF, 126 KB

english, 2012

37

Mechanisms of Manganese-Induced Rat Pheochromocytoma (PC12) Cell Death and Cell Differentiation

Jerome A. Roth, Craig Horbinski, Dennis Higgins, Pamela Lein, Michael D. Garrick

Journal:

NeuroToxicology

Year:

2002

Language:

english

File:

PDF, 166 KB

english, 2002

38

Mechanisms of neuronal polarity

Dennis Higgins, Michelle Burack, Pamela Lein, Gary Banker

Journal:

Current Opinion in Neurobiology

Year:

1997

Language:

english

File:

PDF, 623 KB

english, 1997

39

In vitro and other alternative approaches to developmental neurotoxicity testing (DNT)

Pamela Lein, Ellen Silbergeld, Paul Locke, Alan M. Goldberg

Journal:

Environmental Toxicology and Pharmacology

Year:

2005

Language:

english

File:

PDF, 129 KB

english, 2005

40

PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos

Corie A. Ellison, Alice L. Crane, Matthew R. Bonner, James B. Knaak, Richard W. Browne, Pamela J. Lein, James R. Olson

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 554 KB

english, 2012

41

Experimental strategy for translational studies of organophosphorus pesticide neurotoxicity based on real-world occupational exposures to chlorpyrifos

Pamela J. Lein, Matthew R. Bonner, Fayssal M. Farahat, James R. Olson, Diane S. Rohlman, Richard A. Fenske, K. Matthew Lattal, Michael R. Lasarev, Kit Galvin, Taghreed M. Farahat, W. Kent Anger

Journal:

NeuroToxicology

Year:

2012

Language:

english

File:

PDF, 567 KB

english, 2012

42

Equine viral arteritis in newborn foals: clinical, pathological, serological, microbiological and immunohistochemical observations

F. DEL PIERO, PAMELA A. WILKINS, J. W. LOPEZ, AMY L. GLASER, E. J. DUBOVI, D. H. SCHLAFER, D. H. LEIN

Journal:

Equine Veterinary Journal

Year:

1997

Language:

english

File:

PDF, 5.37 MB

english, 1997

43

2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) and Its Hydroxylated Metabolites Are Enantiomerically Enriched in Female Mice

Kania-Korwel, Izabela, Barnhart, Christopher D., Stamou, Marianna, Truong, Kim M., El-Komy, Mohammed H. M. E., Lein, Pamela J., Veng-Pedersen, Peter, Lehmler, Hans-Joachim

Journal:

Environmental Science & Technology

Year:

2012

Language:

english

File:

PDF, 745 KB

english, 2012

44

Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts

Christoph van Thriel, Remco H.S. Westerink, Christian Beste, Ambuja S. Bale, Pamela J. Lein, Marcel Leist

Journal:

NeuroToxicology

Year:

2012

Language:

english

File:

PDF, 872 KB

english, 2012

45

Protein synthesis is required for the initiation of dendritic growth in embryonic rat sympathetic neurons in vitro

Pamela J. Lein, Dennis Higgins

Journal:

Developmental Brain Research

Year:

1991

Language:

english

File:

PDF, 1009 KB

english, 1991

46

Allele and Genotype Frequencies of CYP2B6 and CYP2C19 Polymorphisms in Egyptian Agricultural Workers

Ellison, Corie A., Abou El-Ella, Soheir S., Tawfik, Maha, Lein, Pamela J., Olson, James R.

Journal:

Journal of Toxicology and Environmental Health

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

47

Characterization of α-cypermethrin exposure in Egyptian agricultural workers

Singleton, Steven T., Lein, Pamela J., Farahat, Fayssal M., Farahat, Taghreed, Bonner, Matthew R., Knaak, James B., Olson, James R.

Journal:

International Journal of Hygiene and Environmental Health

Year:

2014

Language:

english

File:

PDF, 963 KB

english, 2014

48

Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders

Stamou, Marianna, Streifel, Karin M., Goines, Paula E., Lein, Pamela J.

Journal:

Neurotoxicology and Teratology

Year:

2013

Language:

english

File:

PDF, 348 KB

english, 2013

49

Distinct spatial localization of specific mRNAs in cultured sympathetic neurons

Bruckenstein, David A., Lein, Pamela J., Higgins, Dennis, Fremeau, Robert T.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.04 MB

english, 1990

50

Laminin selectively enhances axonal growth and accelerates the development of polarity by hippocampal neurons in culture

Lein, Pamela J., Banker, Gary A., Higgins, Dennis

Journal:

Developmental Brain Research

Year:

1992

Language:

english

File:

PDF, 348 KB

english, 1992