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1

Trends in Snakebite Envenomation Therapy: Scientific, Technological and Public Health Considerations

Gutierrez, Jose, Lomonte, Bruno, Leon, Guillermo, Rucavado, Alexandra, Chaves, Fernando, Angulo, Yamileth

Journal:

Current Pharmaceutical Design

Year:

2007

Language:

english

File:

PDF, 424 KB

english, 2007

2

Editorial: Novel Immunotherapies Against Envenomings by Snakes and Other Venomous Animals

Laustsen, Andreas Hougaard, Ainsworth, Stuart, Lomonte, Bruno, Kini, R. Manjunatha, ChÃ¡vez-OlÃ³rtegui, Carlos

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 163 KB

2020

3

Strategies in ‘snake venomics’ aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

Lomonte, Bruno, Calvete, Juan J.

Journal:

Journal of Venomous Animals and Toxins including Tropical Diseases

Year:

2017

Language:

english

File:

PDF, 1.62 MB

english, 2017

4

Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models

Calvete, Juan J., Bonilla, FabiÃ¡n, Granados-MartÃnez, SofÃa, Sanz, Libia, Lomonte, Bruno, Sasa, Mahmood

Journal:

Journal of Proteomics

Year:

2020

File:

PDF, 913 KB

2020

5

Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management

Juan J. Calvete, Libia Sanz, Alicia Pérez, Adolfo Borges, Alba M. Vargas, Bruno Lomonte, Yamileth Angulo, José María Gutiérrez, Hipócrates M. Chalkidis, Rosa H.V. Mourão, M. Fatima D. Furtado, Ana M.

Journal:

Journal of Proteomics

Year:

2011

Language:

english

File:

PDF, 2.93 MB

english, 2011

6

Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing

Jordi Durban, Paula Juárez, Yamileth Angulo, Bruno Lomonte, Marietta Flores-Diaz, Alberto Alape-Girón, Mahmood Sasa, Libia Sanz, José M Gutiérrez, Joaquín Dopazo, Ana Conesa, Juan J Calvete

Journal:

Year:

2011

Language:

english

File:

PDF, 1.79 MB

english, 2011

7

Evaluacion de la capacidad de cuatro antivenenos comerciales para neutralizar el veneno de la serpiente Bothrops asper (terciopelo) de Costa Rica

Guisella Bogarín, Eduardo Segura, Gina Durán, Bruno Lomonte, Gustavo Rojas, JoséMaría Gutiérrez

Journal:

Year:

1995

File:

PDF, 314 KB

1995

8

Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs

María Herrera, Guillermo León, Alvaro Segura, Fabricio Meneses, Bruno Lomonte, Jean Philippe Chippaux, José María Gutiérrez

Journal:

Year:

2005

Language:

english

File:

PDF, 164 KB

english, 2005

9

Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture

Saravia-Otten, Patricia, Robledo, BáRbara, Escalante, Teresa, Bonilla, Llira, Rucavado, Alexandra, Lomonte, Bruno, Hernández, Rosario, Flock, Jan-Ingmar, Gutiérrez, José María, Gastaldello, Stefano

Journal:

Year:

2013

Language:

english

File:

PDF, 745 KB

english, 2013

10

Pharmacokinetic-Pharmacodynamic Relationships of Immunoglobulin Therapy for Envenomation

José María Gutiérrez, Guillermo León, Bruno Lomonte

Journal:

Clinical Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

11

Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus : Correlation with Toxicological Activities and Immunoreactivity of a Heterologous Antivenom †

Gutiérrez, José María, Sanz, Libia, Escolano, José, Fernández, Julián, Lomonte, Bruno, Angulo, Yamileth, Rucavado, Alexandra, Warrell, David A., Calvete, Juan J.

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 3.50 MB

english, 2008

12

Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: Identification of key toxin targets for antivenom development

Laustsen, Andreas H., Lomonte, Bruno, Lohse, Brian, Fernández, Julián, Gutiérrez, José María

Journal:

Journal of Proteomics

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

13

Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: Proteome, toxicity, and cross-neutralization by antivenom

Rey-Suárez, Paola, Núñez, Vitelbina, Fernández, Julián, Lomonte, Bruno

Journal:

Journal of Proteomics

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

14

Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses

Lomonte, Bruno, Rey-Suárez, Paola, Fernández, Julián, Sasa, Mahmood, Pla, Davinia, Vargas, Nancy, Bénard-Valle, Melisa, Sanz, Libia, Corrêa-Netto, Carlos, Núñez, Vitelbina, Alape-Girón, Alberto, Alagó

Journal:

Year:

2016

Language:

english

File:

PDF, 2.50 MB

english, 2016

15

First description of Cryptosporidium hominis GP60 genotype IkA20G1 and Cryptosporidium parvum GP60 genotypes IIaA18G3R1 and IIaA15G2R1 in foals in Brazil

Inácio, Sandra Valéria, Widmer, Giovanni, de Brito, Roberta Lomonte Lemos, Zucatto, Anaiza Simão, de Aquino, Monally Conceição Costa, Oliveira, Bruno César Miranda, Nakamura, Alex Akira, Neto, Luiz da

Journal:

Veterinary Parasitology

Year:

2017

Language:

english

File:

PDF, 956 KB

english, 2017

16

Comparative characterization of Viperidae snake venoms from PerÃº reveals two compositional patterns of phospholipase A2 expression

Lomonte, Bruno, DÃaz, Cecilia, Chaves, Fernando, FernÃ¡ndez, JuliÃ¡n, Ruiz, Marco, Salas, MarÃa, Zavaleta, Alfonso, Calvete, Juan J., Sasa, Mahmood

Journal:

Year:

2020

File:

PDF, 12.63 MB

2020

17

The earless monitor lizard Lanthanotus borneensis â A venomous animal?

Mebs, Dietrich, Lomonte, Bruno, FernÃ¡ndez, JuliÃ¡n, Calvete, Juan J., Sanz, Libia, Mahlow, Kristin, MÃ¼ller, Johannes, KÃ¶hler, Gunther, Zollweg, Michael

Journal:

Year:

2021

File:

PDF, 4.74 MB

2021

18

Differential susceptibility of C2C12 myoblasts and myotubes to group II phospholipase A2 myotoxins from crotalid snake venoms

Yamileth Angulo, Bruno Lomonte

Journal:

Cell Biochemistry and Function

Year:

2005

Language:

english

File:

PDF, 1.44 MB

english, 2005

19

Membrane cholesterol modulates the cytolytic mechanism of myotoxin II, a Lys49 phospholipase A2 homologue from the venom of Bothrops asper

José Rangel, Orestes Quesada, José María Gutiérrez, Yamileth Angulo, Bruno Lomonte

Journal:

Cell Biochemistry and Function

Year:

2011

Language:

english

File:

PDF, 232 KB

english, 2011

20

Purification and characterization of myotoxin IV, a phospholipase A2 variant, from Bothrops asper snake venom

Cecilia Diaz, Bruno Lomonte, Fernando Zamudio, José María Gutiérrez

Journal:

Year:

1995

Language:

english

File:

PDF, 587 KB

english, 1995

21

Crystallization of the Lys49 PLA2 homologue, myotoxin II, from the venom of Atropoides nummifer

Leandra Watanabe, Lisandra M. Gava, Yamileth Angulo, Bruno Lomonte, Raghuvir K. Arni

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

22

Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms

Cindy Araya, Bruno Lomonte

Journal:

Cell Biology International

Year:

2007

Language:

english

File:

PDF, 541 KB

english, 2007

23

Snake venomics of the South and Central American Bushmasters. Comparison of the toxin composition of Lachesis muta gathered from proteomic versus transcriptomic analysis

Libia Sanz, José Escolano, Massimo Ferretti, Mirtha J. Biscoglio, Elena Rivera, Ernesto J. Crescenti, Yamileth Angulo, Bruno Lomonte, José María Gutiérrez, Juan J. Calvete

Journal:

Journal of Proteomics

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

24

Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming

José María Gutiérrez, Bruno Lomonte, Guillermo León, Alberto Alape-Girón, Marietta Flores-Díaz, Libia Sanz, Yamileth Angulo, Juan J. Calvete

Journal:

Journal of Proteomics

Year:

2009

Language:

english

File:

PDF, 1.07 MB

english, 2009

25

Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism

Vitelbina Núñez, Pedro Cid, Libia Sanz, Pilar De La Torre, Yamileth Angulo, Bruno Lomonte, José María Gutiérrez, Juan J. Calvete

Journal:

Journal of Proteomics

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

26

Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: Isolation of 4-nerolidylcatechol as active principle

Vitelbina Núñez, Víctor Castro, Renato Murillo, Luis A. Ponce-Soto, Irmgard Merfort, Bruno Lomonte

Journal:

Year:

2005

Language:

english

File:

PDF, 225 KB

english, 2005

27

Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice

Monica Lopes-Ferreira, Javier Núñez, Alexandra Rucavado, Sandra H.P. Farsky, Bruno Lomonte, Yamileth Angulo, Ana M. moura Da Silva, José María Gutiérrez

Journal:

International Journal of Experimental Pathology

Year:

2001

Language:

english

File:

PDF, 415 KB

english, 2001

28

Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum

Surza L. G. Rocha, Bruno Lomonte, Ana G. C. Neves-Ferreira, Monique R. O. Trugilho, Inácio de L. M. Junqueira-de-Azevedo, Paulo L. Ho, Gilberto B. Domont, José M. Gutiérrez, Jonas Perales

Journal:

Year:

2002

Language:

english

File:

PDF, 430 KB

english, 2002

29

Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene

Alberto Alape-Girón, Marietta Flores-Díaz, Isabelle Guillouard, Claire E. Naylor, Richard W. Titball, Alexandra Rucavado, Bruno Lomonte, Ajit K. Basak, José M. Gutiérrez, Stewart T. Cole, Monica Thele

Journal:

Year:

2000

Language:

english

File:

PDF, 582 KB

english, 2000

30

Host response toBothrops aspersnake venom

Bruno Lomonte, Andrej Tarkowski, Lars Å. Hanson

Journal:

Year:

1993

Language:

english

File:

PDF, 1.20 MB

english, 1993

31

Biological and Structural Characterization of Crotoxin and New Isoform of Crotoxin B PLA2(F6a) fromCrotalus durissus collilineatusSnake Venom

Luis Alberto Ponce-Soto, Bruno Lomonte, Lea Rodrigues-Simioni, José Camillo Novello, Sergio Marangoni

Journal:

The Protein Journal

Year:

2007

Language:

english

File:

PDF, 425 KB

english, 2007

32

Lys-49-phospholipases A2 as active enzyme for β-arachidonoyl phospholipid bilayer membranes

Yoko Yamaguchi, Yasuyuki Shimohigashi, Tsuyoshi Chiwata, Ayako Tani, Takahisa Chijiwa, Bruno Lomonte, Motonori Ohno

Journal:

Year:

1997

Language:

english

File:

PDF, 482 KB

english, 1997

33

Local Tissue Damage Induced by BaP1, a Metalloproteinase Isolated from Bothrops asper (Terciopelo) Snake Venom

Alexandra Rucavado, Bruno Lomonte, Michael Ovadia, Josée Marı́a Gutiérrez

Journal:

Experimental and Molecular Pathology

Year:

1995

File:

PDF, 1.18 MB

1995

34

Individual expression patterns of myotoxin isoforms in the venom of the snake Bothrops asper

Bruno Lomonte, Elena Carmona

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1992

Language:

english

File:

PDF, 915 KB

english, 1992

35

Comparative study of the edema-forming activity of costa rican snake venoms and its neutralization by a polyvalent antivenom

JoséMaría Gutiérrez, Gustavo Rojas, Bruno Lomonte, JoséA. Gené, Luis Cerdas

Journal:

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Year:

1986

Language:

english

File:

PDF, 618 KB

english, 1986

36

Pharmacological activities of a toxic phospholipase a isolated from the venom of the snake Bothrops Asper

JoséMaría Gutiérrez, Bruno Lomonte, Fernando Chaves, Edgardo Moreno, Luis Cerdas

Journal:

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Year:

1986

Language:

english

File:

PDF, 714 KB

english, 1986

37

Anti-human erythrocyte antibodies in horse-derived antivenoms used in the treatment of snakebite envenomations

Guillermo León, Miguel Angel Rodríguez, Alexandra Rucavado, Bruno Lomonte, José María Gutiérrez

Journal:

Year:

2007

Language:

english

File:

PDF, 841 KB

english, 2007

38

Venoms, venomics, antivenomics

Juan J. Calvete, Libia Sanz, Yamileth Angulo, Bruno Lomonte, José María Gutiérrez

Journal:

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

39

Snake venomics of the pit vipers Porthidium nasutum, Porthidium ophryomegas, and Cerrophidion godmani from Costa Rica: Toxicological and taxonomical insights

Bruno Lomonte, Paola Rey-Suárez, Wan-Chih Tsai, Yamileth Angulo, Mahmood Sasa, José María Gutiérrez, Juan J. Calvete

Journal:

Journal of Proteomics

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

40

Snake venomics and toxicological profiling of the arboreal pitviper Bothriechis supraciliaris from Costa Rica

Bruno Lomonte, Wan-Chih Tsai, Fabián Bonilla, Alejandro Solórzano, Gabriela Solano, Yamileth Angulo, José María Gutiérrez, Juan J. Calvete

Journal:

Year:

2012

Language:

english

File:

PDF, 631 KB

english, 2012

41

Snake venom Lys49 myotoxins: From phospholipases A2 to non-enzymatic membrane disruptors

Bruno Lomonte, José Rangel

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

42

210. Understanding the Preclinical Efficacy Profile of Antivenoms: From the Lethality Potency Assay to Antivenomics

José María Gutiérrez, Bruno Lomonte, Guillermo León, Davinia Plá, Álvaro Segura, María Herrera, Mauren Villalta, Mariángela Vargas, Gabriela Solano, Libia Sanz, Julián Fernández, Yamileth Angulo, Juan

Journal:

Year:

2012

Language:

english

File:

PDF, 48 KB

english, 2012

43

224. Snake Venomics of Crotalus tigris. Evolutionary Clues for Generating a Pan-Specific Antivenom Against Crotalid Type II Venoms

Juan J. Calvete, Alicia Pérez, Bruno Lomonte, Elda E. Sánchez, Libia Sanz

Journal:

Year:

2012

Language:

english

File:

PDF, 47 KB

english, 2012

44

223. TLR2 and MyD88 Signaling are Required for Efficient Response of Macrophages to MT-III a Phospholipase A2 (PLA2) from Bothrops asper Snake Venom

Elbio Leiguez, Karina C. Giannotti, Vanessa Moreira, Márcio H. Matsubara, Bruno Lomonte, Catarina F.P. Teixeira

Journal:

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012

45

196. Synthetic Peptides from Viperid Phospholipase A2 Myotoxins: Small Structures with Diverse Biomimetic Actions

Journal:

Year:

2012

Language:

english

File:

PDF, 49 KB

english, 2012

46

Inhibitory effect of fucoidan on the activities of crotaline snake venom myotoxic phospholipases A2

Yamileth Angulo, Bruno Lomonte

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

47

Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom : Synthetic Lys49 myotoxin II-(115−129)-peptide identifies its bactericidal region

Leandro Páramo, Bruno Lomonte, Javier Pizarro-Cerdá, José-Antonio Bengoechea, Jean-Pierre Gorvel, Edgardo Moreno

Journal:

Year:

1998

Language:

english

File:

PDF, 793 KB

english, 1998

48

Antibodies to Helicobacter pylori in dyspeptic patients, asymptomatic adults, and children from Costa Rica

GISELLE Bartels, ADELITA Herrera, PILAR Salas, RAFAELA Sierra, BRUNO Lomonte

Journal:

Year:

1995

Language:

english

File:

PDF, 411 KB

english, 1995

49

Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America

Calvete, Juan J., Sanz, Libia, Cid, Pedro, de la Torre, Pilar, Flores-Díaz, Marietta, Dos Santos, M. Cristina, Borges, Adolfo, Bremo, Adolfo, Angulo, Yamileth, Lomonte, Bruno

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 4.98 MB

english, 2010

50

Isolation and biochemical, functional and structural characterization of a novel l-amino acid oxidase from Lachesis muta snake venom

Cristiane Bregge-Silva, Maria Cristina Nonato, Sérgio de Albuquerque, Paulo Lee Ho, Inácio L.M. Junqueira de Azevedo, Marcelo Ribeiro Vasconcelos Diniz, Bruno Lomonte, Alexandra Rucavado, Cecilia Díaz

Journal:

Year:

2012

Language:

english

File:

PDF, 1.91 MB

english, 2012