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1

Structure–function relations of the giant elastic protein titin in striated and smooth muscle cells

Henk Granzier, Siegfried Labeit

Journal:

Year:

2007

Language:

english

File:

PDF, 1.07 MB

english, 2007

2

Cloning of the T gene required in mesoderm formation in the mouse

Herrmann, Bernhard G., Labeit, Siegfried, Poustka, Annemarie, King, Thomas R., Lehrach, Hans

Journal:

Year:

1990

File:

PDF, 639 KB

1990

3

A New Method of DNA Sequencing Using Deoxynucleoside α-Thiotriphosphates

LABEIT, SIEGFRIED, LEHRACH, HANS, GOODY, ROGER S.

Journal:

Year:

1986

Language:

english

File:

PDF, 5.15 MB

english, 1986

4

A comparative proteome analysis of human metaphase chromosomes isolated from two different cell lines reveals a set of conserved chromosome-associated proteins

Hideaki Takata, Susumu Uchiyama, Naoko Nakamura, Shoko Nakashima, Shouhei Kobayashi, Takefumi Sone, Sumiko Kimura, Sunshine Lahmers, Henk Granzier, Siegfried Labeit, Sachihiro Matsunaga, Kiichi Fukui

Journal:

Year:

2007

Language:

english

File:

PDF, 437 KB

english, 2007

5

The Giant Muscle Protein Titin is an Adjustable Molecular Spring

Granzier, Henk L., Labeit, Siegfried

Journal:

Exercise and Sport Sciences Reviews

Year:

2006

Language:

english

File:

PDF, 217 KB

english, 2006

6

C-terminal titin deletions cause a novel early-onset myopathy with fatal cardiomyopathy

Virginie Carmignac, Mustafa A. M. Salih, Susana Quijano-Roy, Sylvie Marchand, Molham M. Al Rayess, Maowia M. Mukhtar, Jon A. Urtizberea, Siegfried Labeit, Pascale Guicheney, France Leturcq, Mathias Ga

Journal:

Annals of Neurology

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

7

BAG3 in heart disease: Novel clues for cardiomyocyte survival from the Z-disk?

Siegfried Labeit

Journal:

Year:

2011

Language:

english

File:

PDF, 85 KB

english, 2011

8

The evolution of titin and related giant muscle proteins

Desmond G. Higgins, Siegfried Labeit, Mathias Gautel, Toby J. Gibson

Journal:

Journal of Molecular Evolution

Year:

1994

Language:

english

File:

PDF, 914 KB

english, 1994

9

Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy

Brenda Gerull, John Atherton, Anke Geupel, Sabine Sasse-Klaassen, Arnd Heuser, Michael Frenneaux, Mark McNabb, Henk Granzier, Siegfried Labeit, Ludwig Thierfelder

Journal:

Journal of Molecular Medicine

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

10

Titin: Physiological Function and Role in Cardiomyopathy and Failure

Henk Granzier, Yiming Wu, Labeit Siegfried, Martin LeWinter

Journal:

Heart Failure Reviews

Year:

2005

Language:

english

File:

PDF, 420 KB

english, 2005

11

The function of elastic proteins in the oscillatory contraction of insect flight muscle

Belinda Bullard, Christoph Burkart, Siegfried Labeit, Kevin Leonard

Journal:

Journal of Muscle Research and Cell Motility

Year:

2005

Language:

english

File:

PDF, 455 KB

english, 2005

12

Dimerization of the cardiac ankyrin protein CARP: Implications for MARP titin-based signaling

Stephanie H. Witt, Dietmar Labeit, Henk Granzier, Siegfried Labeit, Christian C. Witt

Journal:

Journal of Muscle Research and Cell Motility

Year:

2005

Language:

english

File:

PDF, 310 KB

english, 2005

13

Restoring force development by titin/connectin and assessment of Ig domain unfolding

Nair Preetha, Wu Yiming, Michiel Helmes, Fukuda Norio, Labeit Siegfried, Henk Granzier

Journal:

Journal of Muscle Research and Cell Motility

Year:

2005

Language:

english

File:

PDF, 485 KB

english, 2005

14

Response to the letter of Drs. Mikhailov and Torrado

Stephanie H. Witt, Siegfried Labeit, Christian C. Witt

Journal:

Journal of Muscle Research and Cell Motility

Year:

2006

Language:

english

File:

PDF, 69 KB

english, 2006

15

Anti-titin and Antiryanodine Receptor Antibodies in Myasthenia Gravis Patients with Thymoma

FULVIO BAGGI, FRANCESCA ANDREETA, CARLO ANTOZZI, ORNELLA SIMONCINI, PAOLO CONFALONIERI, SIEGFRIED LABEIT, FERDINANDO CORNELIO, RENATO MANTEGAZZA

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 367 KB

english, 1998

16

Titin Transcripts in Thymomas

GEIRMOLVE SKEIE, ALEXANDRA FREIBURG, BERNHARD KOLMERER, SIEGFRIED LABEIT, JOHAN A. AARLI, NILS ERIK GILHUS

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 503 KB

english, 1998

17

Cardiac myosin binding protein–C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy

Bonne, Gisèle, Carrier, Lucie, Bercovici, Josiane, Cruaud, Corinne, Richard, Pascale, Hainque, Bernard, Gautel, Mathias, Labeit, Siegfried, James, Michael, Beckmann, Jacques

Journal:

Nature Genetics

Year:

1995

File:

PDF, 522 KB

1995

18

Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy

Gerull, Brenda, Gramlich, Michael, Atherton, John, McNabb, Mark, Trombitás, Karoly, Sasse-Klaassen, Sabine, Seidman, J.G., Seidman, Christine, Granzier, Henk, Labeit, Siegfried

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 568 KB

english, 2002

19

Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo

Witt, Christian C, Burkart, Christoph, Labeit, Dietmar, McNabb, Mark, Wu, Yiming, Granzier, Henk, Labeit, Siegfried

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 782 KB

english, 2006

20

Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2

Witt, Christian C, Witt, Stephanie H, Lerche, Stefanie, Labeit, Dietmar, Back, Walter, Labeit, Siegfried

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 873 KB

english, 2007

21

Cardiac titin: an adjustable multi-functional spring

Henk Granzier, Siegfried Labeit

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 1.51 MB

english, 2002

22

A systematic search of the data bases for sequences homologous to titin/connectin

Bernhard Kolmerer, Nicoletta Olivieri, Bernhard Herrmann, Siegfried Labeit

Journal:

Advances in Biophysics

Year:

1996

Language:

english

File:

PDF, 745 KB

english, 1996

23

Heptitis B and C virus infection in HBsAg-negative alcoholics without i.v. drug abuse or previous blood transfusions

Fritz von Weizsäcker, Eiki Maeda, Nancy Brown, Thierry Poynard, Eithan Galun, Siegfried Labeit, Jean-Claude Caput, Terukatsu Arima, Hubert Blum, Jack R. Wands

Journal:

International Hepatology Communications

Year:

1995

Language:

english

File:

PDF, 533 KB

english, 1995

24

The Structure of Lethocerus Troponin C: Insights into the Mechanism of Stretch Activation in Muscles

Gianfelice De Nicola, Christoph Burkart, Feng Qiu, Bogos Agianian, Siegfried Labeit, Stephen Martin, Belinda Bullard, Annalisa Pastore

Journal:

Year:

2007

Language:

english

File:

PDF, 1.58 MB

english, 2007

25

Muscle assembly: a titanic achievement?

Carol C Gregorio, Henk Granzier, Hiroyuki Sorimachi, Siegfried Labeit

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 146 KB

english, 1999

26

Nebulin: The Nebulous, Multifunctional Giant of Striated Muscle

Abigail S. McElhinny, Steven T. Kazmierski, Siegfried Labeit, Carol C. Gregorio

Journal:

Trends in Cardiovascular Medicine

Year:

2003

Language:

english

File:

PDF, 351 KB

english, 2003

27

Order of Six Loci at 2q24-q31 and Orientation of the HOXD Locus

Elena Rossi, Antonio Faiella, Massimo Zeviani, Siegfried Labeit, Giovanna Floridia, Silvia Brunelli, Marina Cammarata, Edoardo Boncinelli, Orsetta Zuffardi

Journal:

Year:

1994

File:

PDF, 742 KB

1994

28

Titin Transcripts in Thymomas

Geir Olve Skeie, Alexandra Freiburg, Bernhard Kolmerer, Siegfried Labeit, Johan A Aarli, Samuel Appiah-Boadu, Nils Erik Gilhus

Journal:

Journal of Autoimmunity

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

29

Genomic Organization of M Line Titin and its Tissue-specific Expression in Two Distinct Isoforms

Bernhard Kolmerer, Nicoletta Olivieri, Christian C. Witt, Bernhard G. Herrmann, Siegfried Labeit

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 2.17 MB

english, 1996

30

Correlation Between Conformational and Binding Properties of Nebulin Repeats

Mark Pfuhl, Steven J Winder, Maria A Castiglione Morelli, Siegfried Labeit, Annalisa Pastore

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 2.14 MB

english, 1996

31

Towards a Molecular Understanding of the Elasticity of Titin

Wolfgang A. Linke, Marc Ivemeyer, Nicoletta Olivieri, Bernhard Kolmerer, Caspar J. Rüegg, Siegfried Labeit

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 626 KB

english, 1996

32

Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-discs

Stefania Millevoi, Karoly Trombitas, Bernhard Kolmerer, Sawa Kostin, Jutta Schaper, Katarina Pelin, Henk Granzier, Siegfried Labeit

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 1.98 MB

english, 1998

33

Association of kettin with actin in the Z-disc of insect flight muscle

Monique van Straaten, David Goulding, Bernhard Kolmerer, Siegfried Labeit, Jonathan Clayton, Kevin Leonard, Belinda Bullard

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 894 KB

english, 1999

34

Sequence and expression of the kettin gene in Drosophila melanogaster and Caenorhabditis elegans

Bernhard Kolmerer, Jonathan Clayton, Vladimir Benes, Taylor Allen, Charles Ferguson, Kevin Leonard, Ursula Weber, Marika Knekt, Wilhelm Ansorge, Siegfried Labeit, Belinda Bullard

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 1.11 MB

english, 2000

35

Structural and functional studies of titin’s fn3 modules reveal conserved surface patterns and binding to myosin S1 - a possible role in the frank-starling mechanism of the heart

Claudia Muhle-Goll, Michael Habeck, Olivier Cazorla, Michael Nilges, Siegfried Labeit, Henk Granzier

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 1.05 MB

english, 2001

36

Specific interaction of the potassium channel β-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system

Tetsushi Furukawa, Yasuko Ono, Hiroyuki Tsuchiya, Yoshifumi Katayama, Marie-Louise Bang, Dietmar Labeit, Siegfried Labeit, Nobuya Inagaki, Carol C Gregorio

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 700 KB

english, 2001

37

Changes in Titin and Collagen Underlie Diastolic Stiffness Diversity of Cardiac Muscle

Yiming Wu, Olivier Cazorla, Dietmar Labeit, Siegfried Labeit, Henk Granzier

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2000

Language:

english

File:

PDF, 271 KB

english, 2000

38

A Survey of the Primary Structure and the Interspecies Conservation of I-Band Titin's Elastic Elements in Vertebrates

Christian C. Witt, Nicoletta Olivieri, Thomas Centner, Bernhard Kolmerer, Stefania Millevoi, Jane Morell, Dietmar Labeit, Siegfried Labeit, Harald Jockusch, Annalisa Pastore

Journal:

Journal of Structural Biology

Year:

1998

Language:

english

File:

PDF, 2.24 MB

english, 1998

39

Different Molecular Mechanics Displayed by Titin's Constitutively and Differentially Expressed Tandem Ig Segments

Kaori Watanabe, Claudia Muhle-Goll, Miklós S.Z. Kellermayer, Siegfried Labeit, Henk Granzier

Journal:

Journal of Structural Biology

Year:

2002

Language:

english

File:

PDF, 528 KB

english, 2002

40

Molecular Dissection of the Interaction of Desmin with the C-Terminal Region of Nebulin

Marie-Louise Bang, Carol Gregorio, Siegfried Labeit

Journal:

Journal of Structural Biology

Year:

2002

Language:

english

File:

PDF, 188 KB

english, 2002

41

Titin expression in human articular cartilage and cultured chondrocytes : A novel component in articular cartilage biomechanical sensing?

Markus L. Schwarz, Stephanie H. Witt, Barbara Schneider-Wald, Andreas Buettner, Christian C. Witt, Johannes Stoeve, Hanns-Peter Scharf, Siegfried Labeit, Stefan Milz

Journal:

Biomedicine & Pharmacotherapy

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

42

Cardiac titin: Structure, functions and role in disease

Martin M. LeWinter, Yiming Wu, Siegfried Labeit, Henk Granzier

Journal:

Clinica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 1.27 MB

english, 2007

43

The Muscle Ankyrin Repeat Proteins: CARP, ankrd2/Arpp and DARP as a Family of Titin Filament-based Stress Response Molecules

Melanie K. Miller, Marie-Louise Bang, Christian C. Witt, Dietmar Labeit, Charles Trombitas, Kaori Watanabe, Henk Granzier, Abigail S. McElhinny, Carol C. Gregorio, Siegfried Labeit

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 4.10 MB

english, 2003

44

Induction and Myofibrillar Targeting of CARP, and Suppression of the Nkx2.5 Pathway in the MDM Mouse with Impaired Titin-based Signaling

Christian C. Witt, Yasuko Ono, Eva Puschmann, Mark McNabb, Yiming Wu, Michael Gotthardt, Stephanie H. Witt, Markus Haak, Dietmar Labeit, Carol C. Gregorio, Hiroyuki Sorimachi, Henk Granzier, Siegfried

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 2.02 MB

english, 2004

45

MURF-1 and MURF-2 Target a Specific Subset of Myofibrillar Proteins Redundantly: Towards Understanding MURF-dependent Muscle Ubiquitination

Stephanie H. Witt, Henk Granzier, Christian C. Witt, Siegfried Labeit

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 495 KB

english, 2005

46

Expression of Distinct Classes of Titin Isoforms in Striated and Smooth Muscles by Alternative Splicing, and Their Conserved Interaction with Filamins

Siegfried Labeit, Sunshine Lahmers, Christoph Burkart, Chi Fong, Mark McNabb, Stephanie Witt, Christian Witt, Dietmar Labeit, Henk Granzier

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 3.66 MB

english, 2006

47

Modular Proteins from the Drosophila sallimus (sls) Gene and their Expression in Muscles with Different Extensibility

Christoph Burkart, Feng Qiu, Sigrun Brendel, Vladimir Benes, Petra Hååg, Siegfried Labeit, Kevin Leonard, Belinda Bullard

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.85 MB

english, 2007

48

MuRF1-dependent Regulation of Systemic Carbohydrate Metabolism as Revealed from Transgenic Mouse Studies

Stephanie Hirner, Christian Krohne, Alexander Schuster, Sigrid Hoffmann, Stephanie Witt, Ralf Erber, Carsten Sticht, Alexander Gasch, Siegfried Labeit, Dittmar Labeit

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.58 MB

english, 2008

49

Induction of MuRF1 Is Essential for TNF-α-Induced Loss of Muscle Function in Mice

Volker Adams, Norman Mangner, Alexander Gasch, Christian Krohne, Stephan Gielen, Stephanie Hirner, Hermann-Josef Thierse, Christian C. Witt, Axel Linke, Gerhard Schuler, Siegfried Labeit

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

50

MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance

Anselmo S. Moriscot, Igor L. Baptista, Julius Bogomolovas, Christian Witt, Stephanie Hirner, Henk Granzier, Siegfried Labeit

Journal:

Journal of Structural Biology

Year:

2010

Language:

english

File:

PDF, 1.63 MB

english, 2010

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