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1

Retinoic Acid Receptor Ligands Based on the 6-Cyclopropyl-2,4-hexadienoic Acid.

Luc J. Farmer, Lin Zhi, Susan Jeong, William W. Lamph, Deborah L. Osburn, Glenn Croston, Karen S. Flatten, Rich A. Heyman, Alex M. Nadzan

Journal:

Year:

2003

File:

PDF, 161 KB

2003

2

fos and jun interaction: The role of the leucine zipper

Lynn J. Ransone, Jane Visvader, William W. Lamph, Paolo Sassone-Corsi, Inder M. Verma

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 1.98 MB

english, 1989

3

A selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced prostate cancer

Wan-Ching Yen, William W. Lamph

Journal:

Year:

2006

Language:

english

File:

PDF, 234 KB

english, 2006

4

The efficacy of 9-cisretinoic acid in experimental models of cancer

Marco M. Gottardis, William W. Lamph, David R. Shalinsky, Anton Wellstein, Richard A. Heyman

Journal:

Breast Cancer Research and Treatment

Year:

1996

Language:

english

File:

PDF, 931 KB

english, 1996

5

Synergistic effect of a retinoid X receptor-selective ligand bexarotene (LGD1069, Targretin) and paclitaxel (Taxol) in mammary carcinoma

Wan-ching Yen, Rene Y. Prudente, William W. Lamph

Journal:

Breast Cancer Research and Treatment

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

6

Receptor-selective retinoids inhibit the growth of normal and malignant breast cells by inducing G1 cell cycle blockade

Kendall Wu, Elizabeth DuPré, Heetae Kim, Caesar K. Tin-U, Reid P. Bissonnette, William W. Lamph, Powel H. Brown

Journal:

Breast Cancer Research and Treatment

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

7

The rexinoid bexarotene represses cyclin D1 transcription by inducing the DEC2 transcriptional repressor

Yuxin Li, Qiang Shen, Hee-Tae Kim, Reid P. Bissonnette, William W. Lamph, Bingfang Yan, Powel H. Brown

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

8

Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid

Luc J. Farmer, Lin Zhi, Susan Jeong, William W. Lamph, Deborah L. Osburn, Glenn Croston, Karen S. Flatten, Rich A. Heyman, Alex M. Nadzan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

9

Induction of proto-oncogene JUN/AP-1 by serum and TPA

Lamph, William W., Wamsley, Penny, Sassone-Corsi, Paolo, Verma, Inder M.

Journal:

Year:

1988

File:

PDF, 516 KB

1988

10

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

Sassone-Corsi, Paolo, Ransone, Lynn J., Lamph, William W., Verma, Inder M.

Journal:

Year:

1988

File:

PDF, 530 KB

1988

11

Effects of the RXR-specific ligand Targretin on gene expression in carcinogen-induced mammary tumors in the rat

Hermann, Thomas, Tooker, Patricia, Seidel, Martin, Lamph, William

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 29 KB

english, 2001

12

Differentiation and growth inhibition mediated via the RXR:PPARγ heterodimer in colon cancer

Rosemary M. Cesario, Jessica Stone, Wan-Ching Yen, Reid P. Bissonnette, William W. Lamph

Journal:

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

13

The retinoid X receptor agonist bexarotene (Targretin) synergistically enhances the growth inhibitory activity of cytotoxic drugs in non-small cell lung cancer cells

Hermann, Thomas W., Yen, Wan-Ching, Tooker, Patricia, Fan, Bingqi, Roegner, Karen, Negro-Vilar, Andrés, Lamph, William W., Bissonnette, Reid P.

Journal:

Year:

2005

Language:

english

File:

PDF, 362 KB

english, 2005

14

Discovery of Novel Retinoic Acid Receptor Agonists Having Potent Antiproliferative Activity in Cervical Cancer Cells

Zhang, Lin, Nadzan, Alex M., Heyman, Richard A., Love, Deborah L., Mais, Dale E., Croston, Glenn, Lamph, William W., Boehm, Marcus F.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 183 KB

english, 1996

15

Synthesis and Characterization of Nonsteroidal Glucocorticoid Receptor Modulators for Multiple Myeloma

Hudson, Andrew R., Roach, Steven L., Higuchi, Robert I., Phillips, Dean P., Bissonnette, Reid P., Lamph, William W., Yen, Jean, Li, Yongkai, Adams, Mark E., Valdez, Lino J., Vassar, Angie, Cuervo, Cat

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 414 KB

english, 2007

16

fos-associated cellular p39 is related to nuclear transcription factor AP-1

Sassone-Corsi, Paolo, Lamph, William W., Kamps, Mark, Verma, Inder M.

Journal:

Year:

1988

Language:

english

File:

PDF, 2.05 MB

english, 1988

17

66 The combination of taxol and a selective retinoid X-receptor ligand targretin® (LGD1069) prevents and overcomes acquired taxol resistance in breast carcinoma

Yen, Wan-Ching, Prudente, Rene Y., Roegner, Karen R., Bissonnette, Reid P., Lamph, William W.

Journal:

Year:

2003

Language:

english

File:

PDF, 189 KB

english, 2003

18

Negative and Positive Regulation by Transcription Factor cAMP Response Element-Binding Protein is Modulated by Phosphorylation

William W. Lamph, V. J. Dwarki, Rivka Ofir, Marc Montminy and Inder M. Verma

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.14 MB

english, 1990

19

The Combination of the Rexinoid, LG100268, and a Selective Estrogen Receptor Modulator, Either Arzoxifene or Acolbifene, Synergizes in the Prevention and Treatment of Mammary Tumors in an Estrogen Receptor-Negative Model of Breast Cancer

Liby, K., Rendi, M., Suh, N., Royce, D. B., Risingsong, R., Williams, C. R., Lamph, W., Labrie, F., Krajewski, S., Xu, X., Kim, H., Brown, P., Sporn, M. B.

Journal:

Clinical Cancer Research

Year:

2006

Language:

english

File:

PDF, 476 KB

english, 2006

20

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis

Liby, K., Black, C. C., Royce, D. B., Williams, C. R., Risingsong, R., Yore, M. M., Liu, X., Honda, T., Gribble, G. W., Lamph, W. W., Sporn, T. A., Dmitrovsky, E., Sporn, M. B.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 496 KB

english, 2008

21

Prevention and Treatment of Experimental Estrogen Receptor-Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268

Liby, K., Risingsong, R., Royce, D. B., Williams, C. R., Yore, M. M., Honda, T., Gribble, G. W., Lamph, W. W., Vannini, N., Sogno, I., Albini, A., Sporn, M. B.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 536 KB

english, 2008

22

Platelet Derived Growth Factor (Pdgf), Androgens and Inflammation: Possible Etiologic Factors in the Development of Prostatic Hyperplasia

Gleason, Philip E., Jones, Jeff A., Regan, John S., Salvas, Dan B., Eble, John N., Lamph, William W., Vlahos, Chris J., Huang, Wei-Li, Falcone, Julie F., Hirsch, Kenneth S.

Journal:

The Journal of Urology

Year:

1993

Language:

english

File:

PDF, 297 KB

english, 1993

23

The Retinoid X Receptor-Selective Retinoid, LGD1069, Down-regulates Cyclooxygenase-2 Expression in Human Breast Cells through Transcription Factor Crosstalk: Implications for Molecular-Based Chemoprevention

Kong, Gu, Kim, Hee-Tae, Wu, Kendall, DeNardo, David, Hilsenbeck, Susan G., Xu, Xiao-Chun, Lamph, William W., Bissonnette, Reid, Dannenberg, Andrew J., Brown, Powel H.

Journal:

Cancer Research

Year:

2005

Language:

english

File:

PDF, 628 KB

english, 2005

24

Transformation-Defective Virus Generation from Cloned Nondefective Avian Sarcoma Virus

Wright, Stephen E., Harmon, Shirley A., Lamph, William W.

Journal:

Year:

1980

Language:

english

File:

PDF, 626 KB

english, 1980

25

Induction of Apoptosis Without Differentiation by Retinoic Acid in PLB-985 Cells Requires the Activation of Both RAR and RXR

Monczak, Yury, Trudel, Michel, Lamph, William W., Miller, Wilson H.

Journal:

Year:

1997

Language:

english

File:

PDF, 787 KB

english, 1997

26

A Retinoid-Resistant Acute Promyelocytic Leukemia Subclone Expresses a Dominant Negative PML-RARÎ± Mutation

Shao, Wenlin, Benedetti, Laura, Lamph, William W., Nervi, Clara, Miller, Wilson H.

Journal:

Year:

1997

File:

PDF, 550 KB

1997

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