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1

Unique Physicochemical Profile of β-Amyloid Peptide Variant Aβ1–40E22G Protofibrils: Conceivable Neuropathogen in Arctic Mutant Carriers

A Päiviö, J Jarvet, A Gräslund, L Lannfelt, A Westlind-Danielsson

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 496 KB

english, 2004

2

Allelic association but only weak evidence for linkage to the apolipoprotein E locus in late-onset Swedish Alzheimer families

Liu, Li, Forsell, Charlotte, Lilius, Lena, Axelman, Karin, Corder, Elizabeth H., Lannfelt, Lars

Journal:

American Journal of Medical Genetics

Year:

1996

File:

PDF, 436 KB

1996

3

The genetics and pathophysiology of Alzheimer's disease

Journal:

Journal of Internal Medicine

Year:

1997

Language:

english

File:

PDF, 175 KB

english, 1997

4

The role of APOE polymorphisms in late-onset dementias

E. H. Corder, L. Lannfelt, N. Bogdanovic, L. Fratiglioni, H. Mori

Journal:

Cellular and Molecular Life Sciences

Year:

1998

Language:

english

File:

PDF, 138 KB

english, 1998

5

Docosahexaenoic acid stabilizes soluble amyloid-β protofibrils and sustains amyloid-β-induced neurotoxicity in vitro

Ann-Sofi Johansson, Anita Garlind, Fredrik Berglind-Dehlin, Göran Karlsson, Katarina Edwards, Pär Gellerfors, Frida Ekholm-Pettersson, Jan Palmblad, Lars Lannfelt

Journal:

Year:

2007

Language:

english

File:

PDF, 432 KB

english, 2007

6

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid

Mullan, Mike, Crawford, Fiona, Axelman, Karin, Houlden, Henry, Lilius, Lena, Winblad, Bengt, Lannfelt, Lars

Journal:

Nature Genetics

Year:

1992

File:

PDF, 348 KB

1992

7

Genetic Analysis of Alzheimer’s Disease in the Uppsala Longitudinal Study of Adult Men

Giedraitis, Vilmantas, Kilander, Lena, Degerman-Gunnarsson, Malin, Sundel&ouml, f, Johan, Axelsson, Tomas, Syv&auml, nen, Ann-Christine, Lannfelt, Lars, Glaser, Anna

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

2009

Language:

english

File:

PDF, 517 KB

english, 2009

8

A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status

Sood, Sanjana, Gallagher, Iain J., Lunnon, Katie, Rullman, Eric, Keohane, Aoife, Crossland, Hannah, Phillips, Bethan E., Cederholm, Tommy, Jensen, Thomas, van Loon, Luc JC, Lannfelt, Lars, Kraus, Will

Journal:

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

9

Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus

A. Chase, W. Leung, W. Tapper, A. V. Jones, L. Knoops, C. Rasi, L. A. Forsberg, P. Guglielmelli, K. Zoi, V. Hall, L. Chiecchio, L. Eder-azanza, C. Bryant, L. Lannfelt, L. Docherty, H. E. White, J. Sco

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

10

[Methods in Pharmacology and Toxicology] Immunotherapy and Biomarkers in Neurodegenerative Disorders ||

Ingelsson, Martin, Lannfelt, Lars

Year:

2016

Language:

english

File:

PDF, 9.78 MB

english, 2016

11

No Association Between Familial Alzheimer Disease and Cytochrome P450 Polymorphisms

Yamada, Hiroshi, Dahl, Marja-Liisa, Viitanen, Matti, Winblad, Bengt, Sjöqvist, Folke, Lannfelt, Lars

Journal:

Alzheimer Disease & Associated Disorders

Year:

1998

File:

PDF, 274 KB

1998

12

Life Situation, Coping and Quality of Life in People with High and Low Risk of Developing Alzheimer’s Disease

Axelman, Karin, Lannfelt, Lars, Almkvist, Ove, Carlsson, Marianne

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

2003

Language:

english

File:

PDF, 81 KB

english, 2003

13

CRISPR/Cas9 mediated disruption of the Swedish APP allele as a therapeutic approach for early-onset Alzheimer’s disease

György, B., Lööv, C., Zaborowski, M.P., Takeda, S., Kleinstiver, B.P., Commins, C., Kastanenka, K., Mu, D., Volak, A., Giedraitis, V., Lannfelt, L., Maguire, C.A., Joung, J.K., Hyman, B.T., Breakefiel

Journal:

Molecular Therapy — Nucleic Acids

Year:

2018

Language:

english

File:

PDF, 16.72 MB

english, 2018

14

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

Sardar Sinha, Maitrayee, Ansell-Schultz, Anna, Civitelli, Livia, Hildesjö, Camilla, Larsson, Max, Lannfelt, Lars, Ingelsson, Martin, Hallbeck, Martin

Journal:

Acta Neuropathologica

Year:

2018

Language:

english

File:

PDF, 3.73 MB

english, 2018

15

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-Î² in Brain

SyvÃ¤nen, Stina, Fang, Xiaotian T, FaresjÃ¶, Rebecca, Rokka, Johanna, Lannfelt, Lars, Olberg, Dag E, Eriksson, Jonas, Sehlin, Dag

Journal:

ACS Chemical Neuroscience

Year:

2020

File:

PDF, 3.78 MB

2020

16

Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21

Froelich, Susanne, Basun, Hans, Forsell, Charlotte, Lilius, Lena, Axelman, Karin, Andreadis, Athena, Lannfelt, Lars

Journal:

American Journal of Medical Genetics

Year:

1997

Language:

english

File:

PDF, 76 KB

english, 1997

17

Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population

Kwan-Fu Rex Sheu, Abraham M. Brown, Vahram Haroutunian, Bruce S. Kristal, Howard Thaler, Martin Lesser, Rajesh N. Kalaria, Norman R. Relkin, Richard C. Mohs, Lena Lilius, Lars Lannfelt, John P. Blass

Journal:

Annals of Neurology

Year:

1999

Language:

english

File:

PDF, 485 KB

english, 1999

18

Cerebrospinal fluid Aβ42 is increased early in sporadic Alzheimer's disease and declines with disease progression

Malene Jensen, Johannes Schröder, Mari Blomberg, Benita Engvall, Johannes Pantel, Nobuo Ida, Hans Basun, Lars-Olof Wahlund, Egon Werle, Marek Jauss, Konrad Beyreuther, Lars Lannfelt, Tobias Hartmann

Journal:

Annals of Neurology

Year:

1999

Language:

english

File:

PDF, 234 KB

english, 1999

19

No association between schizophrenia and homozygosity at the D3 dopamine receptor gene

Liu Yang, Tao Li, Claudia Wiese, Lars Lannfelt, Pierre Sokoloff, Chong T. Xu, Zhong Zeng, Jean-Charles Schwartz, Professor Xiehe Liu, Hans W. Moises

Journal:

American Journal of Medical Genetics Part A

Year:

1993

Language:

english

File:

PDF, 457 KB

english, 1993

20

Extended investigation of tau and mutation screening of other candidate genes on chromosome 17q21 in a Swedish FTDP-17 family

Susanne Froelich Fabre, Pia Axelman, Åsa Almkvist, Hans Basun, Lars Lannfelt

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

21

Amyloid-β oligomers are inefficiently measured by enzyme-linked immunosorbent assay

Charlotte Stenh, Hillevi Englund, Anna Lord, Ann-Sofi Johansson, Claudia G. Almeida, Pär Gellerfors, Paul Greengard, Gunnar K. Gouras, Lars Lannfelt, Lars N. G. Nilsson

Journal:

Annals of Neurology

Year:

2005

Language:

english

File:

PDF, 150 KB

english, 2005

22

α-ketoglutarate dehydrogenase in alzheimer brains bearing the APP670/671 mutation

Dr. G. E. Gibson, H. Zhang, K. F. -R. Sheu, N. Bogdanovich, J. G. Lindsay, L. Lannfelt, M. Vestling, R. F. Cowburn

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 711 KB

english, 1998

23

The Glu318Gly mutation of the presenilin-1 gene does not necessarily cause Alzheimer's disease

Dr. Kari M. Mattila, Charlotte Forsell, Tuula Pirttila, Juha O. Rinne, Terho Lehtimaki, Matias Roytta, Lena Lilius, Anne Eerola, Peter H. St George-Hyslop, Harry Frey, Lars Lannfelt

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 312 KB

english, 1998

24

Apolipoprotein E ϵ4 allele, skin vessel reactivity and vascular risk factors in Alzheimer's disease

Annica Algotsson, Agneta Nordberg, Lars Lannfelt, Ove Almkvist, Bengt Winblad

Journal:

Archives of Gerontology and Geriatrics

Year:

1996

Language:

english

File:

PDF, 600 KB

english, 1996

25

Clinical findings in nondemented mutation carriers predisposed to Alzheimer's disease: a model of mild cognitive impairment

Ove Almkvist, Karin Axelman, Hans Basun, Malene Jensen, Matti Viitanen, Lars-Olof Wahlund, Lars Lannfelt

Journal:

Acta Neurologica Scandinavica

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

26

A methylenetetrahydrofolate reductase gene polymorphism in ischaemic stroke and in carotid artery stenosis

Kostulas, Crisby, Huang, Lannfelt, Hagenfeldt, Eggertsen, Kostulas, Hillert

Journal:

European Journal of Clinical Investigation

Year:

1998

Language:

english

File:

PDF, 305 KB

english, 1998

27

An angiotensin-converting enzyme gene polymorphism suggests a genetic distinction between ischaemic stroke and carotid stenosis

K. Kostulas, W.-X. Huang, M. Crisby, Y.-P. Jin, B. He, L. Lannfelt, G. Eggertsen, V. Kostulas, J. Hillert

Journal:

European Journal of Clinical Investigation

Year:

1999

Language:

english

File:

PDF, 104 KB

english, 1999

28

Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs

Elin S Blom, Vilmantas Giedraitis, Sampath Arepalli, Marian L Hamshere, Omanma Adighibe, Alison Goate, Julie Williams, Lars Lannfelt, John Hardy, Wavrant-De Fabienne Vrièze, Anna Glaser

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 637 KB

english, 2009

29

The commonFTOvariant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Josefin A Jacobsson, Ulf Risérus, Tomas Axelsson, Lars Lannfelt, Helgi B Schiöth, Robert Fredriksson

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 1.15 MB

english, 2009

30

Genetic heterogeneity of the porphobilinogen deaminase gene in Swedish families with acute intermittent porphyria

Jin-Sung Lee, Gunnel Lundin, Maria Anvret, Lars Lannfelt, Lotta Forsell, Christiane Picat, Bernard Grandchamp

Journal:

Year:

1991

Language:

english

File:

PDF, 587 KB

english, 1991

31

No amyloid precursor protein 708 mutation in 50 Swedish Alzheimer's disease patients

Lena Lilius, Lars Lannfelt

Journal:

Year:

1994

Language:

english

File:

PDF, 200 KB

english, 1994

32

DNA polymorphisms within the porphobilinogen deaminase gene in two Swedish families with acute intermittent porphyria

Jin-Sung Lee, Maria Anvret, Jan Lindsten, Lars Lannfelt, Pär Gellerfors, Lennart Wetterberg, Ylva Floderus, Stig Thunell

Journal:

Year:

1988

Language:

english

File:

PDF, 286 KB

english, 1988

33

Lack of association between schizophrenia and the apolipoprotein E ε4 allele

E. Jönsson, G. Sedvall, L. Lannfelt, B. Engvall

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1996

Language:

english

File:

PDF, 360 KB

english, 1996

34

Characterization of muscarinic acetylcholine receptors in cultured adult skin fibroblasts: Effects of the swedish Alzheimer's disease APP 670/671 mutation on binding levels

M. Vestling, R. F. Cowburn, N. Venizelos, L. Lannfelt, B. Winblad, A. Adem Ph. D.

Journal:

Journal of Neural Transmission - Parkinson's Disease and Dementia Section

Year:

1995

Language:

english

File:

PDF, 630 KB

english, 1995

35

USF1gene variants contribute to metabolic traits in men in a longitudinal 32-year follow-up study

K. Auro, K. Kristiansson, B. Zethelius, C. Berne, L. Lannfelt, M.-R. Taskinen, M. Jauhiainen, M. Perola, L. Peltonen, A.-C. Syvänen

Journal:

Year:

2008

Language:

english

File:

PDF, 176 KB

english, 2008

36

Glucose metabolism and the risk of Alzheimer’s disease and dementia: a population-based 12

E. Rönnemaa, B. Zethelius, J. Sundelöf, J. Sundström, M. Degerman-Gunnarsson, L. Lannfelt, C. Berne, L. Kilander

Journal:

Year:

2009

Language:

english

File:

PDF, 187 KB

english, 2009

37

Separation and characterization of aggregated species of amyloid-beta peptides

Henning Wiberg, Patrik Ek, Frida Ekholm Pettersson, Lars Lannfelt, Åsa Emmer, Johan Roeraade

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 328 KB

english, 2010

38

CYP2D6 and CYP2C19 genotypes in an elderly Swedish population

H. Yamada, M.-L. Dahl, L. Lannfelt, M. Viitanen, B. Winblad, F. Sjöqvist

Journal:

European Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 130 KB

english, 1998

39

In vivo amyloid imaging with PET in frontotemporal dementia

Henry Engler, Alexander Frizell Santillo, Shu Xia Wang, Maria Lindau, Irina Savitcheva, Agneta Nordberg, Lars Lannfelt, Bengt Långström, Lena Kilander

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2008

Language:

english

File:

PDF, 184 KB

english, 2008

40

In vivo imaging of astrocytosis in Alzheimer’s disease: an11C-L-deuteriodeprenyl and PIB PET study

Alexander Frizell Santillo, Juan Pablo Gambini, Lars Lannfelt, Bengt Långström, Luohija Ulla-Marja, Lena Kilander, Henry Engler

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2011

Language:

english

File:

PDF, 227 KB

english, 2011

41

Circulating immune complexes of Aβ and IgM in plasma of patients with Alzheimer’s disease

Andrea Marcello, Oliver Wirths, Thomas Schneider-Axmann, Malin Degerman-Gunnarsson, Lars Lannfelt, Thomas A. Bayer

Journal:

Journal of Neural Transmission

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

42

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

Oliver Wirths, Tobias Bethge, Andrea Marcello, Anja Harmeier, Sadim Jawhar, Paul J. Lucassen, Gerd Multhaup, David L. Brody, Thomas Esparza, Martin Ingelsson, Hannu Kalimo, Lars Lannfelt, Thomas A. Ba

Journal:

Journal of Neural Transmission

Year:

2010

Language:

english

File:

PDF, 694 KB

english, 2010

43

Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation

Lena Skoglund, RoseMarie Brundin, Tommie Olofsson, Hannu Kalimo, Sofie Ingvast, Elin S. Blom, Vilmantas Giedraitis, Martin Ingelsson, Lars Lannfelt, Hans Basun, Anna Glaser

Journal:

Year:

2009

Language:

english

File:

PDF, 268 KB

english, 2009

44

Apolipoprotein E ε4 Genotype is Independently Associated with Increased Intima-Media Thickness in a Recessive Pattern

M. Wohlin, J. Sundström, Lars Lannfelt, Tomas Axelsson, A. C. Syvänen, B. Andrén, S. Basu, L. Lind

Journal:

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

45

Apolipoprotein E type ε4 allele, heritability and age at onset in twins with Alzheimer disease and vascular dementia

A. L. Mina Bergem, Lars Lannfelt

Journal:

Clinical Genetics

Year:

1997

Language:

english

File:

PDF, 526 KB

english, 1997

46

Docosahexaenoic acid stimulates non-amyloidogenic APP processing resulting in reduced Aβ levels in cellular models of Alzheimer's disease

Charlotte Sahlin, Frida Ekholm Pettersson, Lars N. G. Nilsson, Lars Lannfelt, Ann-Sofi Johansson

Journal:

European Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 673 KB

english, 2007

47

Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders

Charlotte Israelsson, Henrik Bengtsson, Anna Lobell, Lars N. G. Nilsson, Annika Kylberg, Magnus Isaksson, Hanna Wootz, Lars Lannfelt, Klas Kullander, Lars Hillered, Ted Ebendal

Journal:

European Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 532 KB

english, 2010

48

The tau S305S mutation causes frontotemporal dementia with parkinsonism

L. Skoglund, M. Viitanen, H. Kalimo, L. Lannfelt, M. E. Jönhagen, M. Ingelsson, A. Glaser, R. Herva

Journal:

European Journal of Neurology

Year:

2008

Language:

english

File:

PDF, 312 KB

english, 2008

49

The Arctic Alzheimer mutation favors intracellular amyloid-β production by making amyloid precursor protein less available to α-secretase

Charlotte Sahlin, Anna Lord, Kristina Magnusson, Hillevi Englund, Claudia G. Almeida, Paul Greengard, Fred Nyberg, Gunnar K. Gouras, Lars Lannfelt, Lars N.G. Nilsson

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 674 KB

english, 2007

50

The stability of AQT processing speed, ADAS-Cog and MMSE during acetylcholinesterase inhibitor treatment in Alzheimer’s disease

E. H. Wiig, P. Annas, H. Basun, N. Andreasen, L. Lannfelt, H. Zetterberg, K. Blennow, L. Minthon

Journal:

Acta Neurologica Scandinavica

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

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