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51

A Reevaluation of the Role of the Unfolded Protein Response in Islet Dysfunction: Maladaptation or a Failure to Adapt?

Herbert, Terence P., Laybutt, D. Ross

Journal:

Year:

2016

Language:

english

File:

PDF, 780 KB

english, 2016

52

The role of NPY in obesity-induced bone loss

Baldock, Paul A., Lee, Nicola J., Laybutt, Ross, Herzog, Herbert

Journal:

Year:

2016

Language:

english

File:

PDF, 53 KB

english, 2016

53

Beta-cell adaptation to hyperglycemia

Laybutt, R., Hasenkamp, W., Groff, A., Grey, S., Jonas, J., Kaneto, H., Sharma, A., Bonner-Weir, S., Weir, G.

Journal:

Year:

2001

Language:

english

File:

PDF, 32 KB

english, 2001

54

Potential role of the early response gene c-myc in beta-cell adaptation to changes in glucose concentration

Jonas, J., Laybutt, R., Steil, G. M., Trivedi, N., Weir, G. C., Henquin, J.

Journal:

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

55

Casitas b-Lineage Lymphoma-Deficient Mice Are Protected Against High-Fat Diet-Induced Obesity and Insulin Resistance

Molero, J. C., Waring, S. G., Cooper, A., Turner, N., Laybutt, R., Cooney, G. J., James, D. E.

Journal:

Year:

2006

Language:

english

File:

PDF, 312 KB

english, 2006

56

A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking

Boslem, Ebru, MacIntosh, Gemma, Preston, Amanda M., Bartley, Clarissa, Busch, Anna K., Fuller, Maria, Laybutt, D. Ross, Meikle, Peter J., Biden, Trevor J.

Journal:

Biochemical Journal

Year:

2011

Language:

english

File:

PDF, 814 KB

english, 2011

57

A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking

Boslem, E., MacIntosh, G., Preston, A.M., Bartley, C., Busch, A.K., Fuller, M., Laybutt, D.R., Meikle, P.J., Biden, T.J.

Journal:

Biochemical Journal

Year:

2011

Language:

english

File:

PDF, 242 KB

english, 2011

58

Hyper-activation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Upregulating the Proteostatic Machinery in Adipocytes

Minard, Annabel Y., Wong, Martin K. L., Chaudhuri, Rima, Tan, Shi-Xiong, Humphrey, Sean J., Parker, Benjamin L., Yang, Jean Y., Laybutt, D. Ross, Cooney, Gregory J., Coster, Adelle C. F., Stoeckli, Ja

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.72 MB

english, 2016

59

Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

Motterle, Anna, Gattesco, Sonia, Peyot, Marie-Line, Esguerra, Jonathan Lou S., Gomez-Ruiz, Ana, Laybutt, D. Ross, Gilon, Patrick, Burdet, Frédéric, Ibberson, Mark, Eliasson, Lena, Prentki, Marc, Regaz

Journal:

Molecular Metabolism

Year:

2017

Language:

english

File:

PDF, 1.81 MB

english, 2017

60

Circular RNAs as novel regulators of β-cell functions in normal and disease conditions

Stoll, Lisa, Sobel, Jonathan, Rodriguez-Trejo, Adriana, Guay, Claudiane, Lee, Kailun, Venø, Morten Trillingsgaard, Kjems, Jørgen, Laybutt, D. Ross, Regazzi, Romano

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

61

Evidence against a role for NLRP3-driven islet inflammation in db/db mice

Kammoun, H.L., Allen, T.L., Henstridge, D.C., Barre, S., Coll, R.C., Lancaster, G.I., Cron, L., Reibe, S., Chan, J.Y., Bensellam, M., Laybutt, D.R., Butler, M.S., Robertson, A.A.B., O'Neill, L.A., Coo

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 1.03 MB

english, 2018

62

Osteoglycin, a novel coordinator of bone and glucose homeostasis

Lee, N.J., Ali, N., Zhang, L., Qi, Y., Clarke, I., Enriquez, R.F., Brzozowska, M., Lee, I.C., Rogers, M.J., Laybutt, D.R., Center, J.R., Baldock, P.A., Herzog, H.

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 3.28 MB

english, 2018

63

Glucose-Induced O2 Consumption Activates Hypoxia Inducible Factors 1 and 2 in Rat Insulin-Secreting Pancreatic Beta-Cells

Bensellam, Mohammed, Duvillié, Bertrand, Rybachuk, Galyna, Laybutt, D. Ross, Magnan, Christophe, Guiot, Yves, Pouysségur, Jacques, Jonas, Jean-Christophe, Gaetano, Carlo

Journal:

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

64

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia

Pinho, Andreia V., Bensellam, Mohammed, Wauters, Elke, Rees, Maxine, Giry-Laterriere, Marc, Mawson, Amanda, Ly, Le Quan, Biankin, Andrew V., Wu, Jianmin, Laybutt, D. Ross, Rooman, Ilse, Itkin-Ansari,

Journal:

Year:

2015

Language:

english

File:

PDF, 3.05 MB

english, 2015

65

Contribution of the Long Non-Coding RNA H19 to Neonatal and Adult Rodent β-Cell Mass Expansion

Sanchez-Parra, Clara, Jacovetti, Cécile, Dumortier, Olivier, Lee, Kailun, Peyot, Marie-Line, Guay, Claudiane, Prentki, Marc, Laybutt, D. Ross, Van Obberghen, Emmanuel, Regazzi, Romano

Journal:

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

66

Selective chronic regulation of GLUT1 and GLUT4 content by insulin, glucose, and lipid in rat cardiac muscle in vivo

Laybutt, D. R., Thompson, A. L., Cooney, G. J., Kraegen, E. W.

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

1997

Language:

english

File:

PDF, 2.20 MB

english, 1997

67

Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat

Laybutt, D. Ross, Schmitz-Peiffer, Carsten, Saha, Asish K., Ruderman, Neil B., Biden, Trevor J., Kraegen, Edward W.

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

1999

Language:

english

File:

PDF, 160 KB

english, 1999

68

Deletion distal to the PAX6 coding region reveals a novel basis for familial cosegregation of aniridia and diabetes mellitus

Macdonald, Gemma C., Hesselson, Stephanie E., Chan, Jeng Yie, Jenkins, Arthur B, Laybutt, D. Ross, Hesselson, Daniel, Campbell, Lesley V.

Journal:

Diabetes Research and Clinical Practice

Year:

2018

Language:

english

File:

PDF, 800 KB

english, 2018

69

Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo

Saha, Asish K., Laybutt, D. Ross, Dean, David, Vavvas, Demetrios, Sebokova, Elena, Ellis, Bronwyn, Klimes, Iwar, Kraegen, Edward W., Shafrir, Eleazar, Ruderman, Neil B.

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

1999

Language:

english

File:

PDF, 180 KB

english, 1999

70

Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes

Chan, Jeng Yie, Lee, Kailun, Maxwell, Emma L., Liang, Cassandra, Laybutt, D. Ross

Journal:

Year:

2019

File:

PDF, 1.13 MB

2019

71

Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes

Chan, Jeng Yie, Lee, Kailun, Maxwell, Emma L., Liang, Cassandra, Laybutt, D. Ross

Journal:

Year:

2019

Language:

english

File:

PDF, 1.13 MB

english, 2019

72

β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes

Lalwani, Amit, Warren, Joanna, Liuwantara, David, Hawthorne, Wayne J., O’Connell, Philip J., Gonzalez, Frank J., Stokes, Rebecca A., Chen, Jennifer, Laybutt, D. Ross, Craig, Maria E., Swarbrick, Micha

Journal:

Year:

2019

Language:

english

File:

PDF, 7.28 MB

english, 2019

73

β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes

Lalwani, Amit, Warren, Joanna, Liuwantara, David, Hawthorne, Wayne J., O’Connell, Philip J., Gonzalez, Frank J., Stokes, Rebecca A., Chen, Jennifer, Laybutt, D. Ross, Craig, Maria E., Swarbrick, Micha

Journal:

Year:

2019

File:

PDF, 7.28 MB

2019

74

Osteoglycin, a novel coordinator of bone and glucose homeostasis

Lee, Nicola J., Ali, N., Zhang, L., Qi, Y., Clarke, I., Enriquez, R.F., Brzozowska, M., Lee, I.C., Rogers, M.J., Laybutt, D.R., Center, J.R., Baldock, P.A., Herzog, Herbert

Journal:

Obesity Research & Clinical Practice

Year:

2019

Language:

english

File:

PDF, 284 KB

english, 2019

75

Osteoglycin, a novel coordinator of bone and glucose homeostasis

Lee, Nicola J., Ali, N., Zhang, L., Qi, Y., Clarke, I., Enriquez, R.F., Brzozowska, M., Lee, I.C., Rogers, M.J., Laybutt, D.R., Center, J.R., Baldock, P.A., Herzog, Herbert

Journal:

Obesity Research & Clinical Practice

Year:

2019

File:

PDF, 284 KB

2019

76

Phlda3 regulates beta cell survival during stress

Bensellam, Mohammed, Chan, Jeng Yie, Lee, Kailun, Joglekar, Mugdha V., Hardikar, Anandwardhan A., Loudovaris, Thomas, Thomas, Helen E., Jonas, Jean-Christophe, Laybutt, D. Ross

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 3.21 MB

english, 2019

77

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

Bensellam, Mohammed, Shi, Yan-Chuan, Chan, Jeng Yie, Laybutt, D. Ross, Chae, Heeyoung, Abou-Samra, Michel, Pappas, Evan G., Thomas, Helen E., Gilon, Patrick, Jonas, Jean-Christophe

Journal:

Year:

2019

File:

PDF, 2.15 MB

2019

78

Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion

Guay, Claudiane, Abdulkarim, Baroj, Tan, Jennifer Y., Dubuis, Gilles, RÃ¼tti, Sabine, Ross Laybutt, David, Widmann, Christian, Regazzi, Romano, Marques, Ana Claudia

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.17 MB

2020

79

A fluorescent timer reporter enables sorting of insulin secretory granules by age

Yau, Belinda, Hays, Lori, Liang, Cassandra, Laybutt, David Ross, Thomas, Helen E, Gunton, Jenny E, Williams, Lindy, Hawthorne, Wayne J, Thorn, Peter, Rhodes, Christopher J., Kebede, Melkam A

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 2.94 MB

2020

80

Epidemics will always come (and go): the need to prepare for the next one, research on COVID-19, and the role of molecular and cellular endocrinology

Stratakis, Constantine A., Laybutt, D. Ross, Laudet, Vincent, Klinge, Carolyn M.

Journal:

Molecular and Cellular Endocrinology

Year:

2020

File:

PDF, 441 KB

2020

81

Publisher Correction: Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion

Guay, Claudiane, Abdulkarim, Baroj, Tan, Jennifer Y., Dubuis, Gilles, RÃ¼tti, Sabine, Laybutt, David Ross, Widmann, Christian, Regazzi, Romano, Marques, Ana Claudia

Journal:

Scientific Reports

Year:

2020

File:

PDF, 638 KB

2020