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1

Design, synthesis, chemical characterization, biological evaluation, and docking study of new 1,3,4-oxadiazole homonucleoside analogs

El Mansouri, Az-Eddine, Maatallah, Mohamed, Ait Benhassou, Hassan, Moumen, Abdeladim, Mehdi, Ahmad, Snoeck, Robert, Andrei, Graciela, Zahouily, Mohamed, Lazrek, Hassan B.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2020

File:

PDF, 2.68 MB

2020

2

Regioselective Synthesis of 9-[(2-Hydroxyethoxy)Methyl]-6-Benzylaminopurine Analogue of Acyclovir

Mohamed L Taha, Hassan B. Lazrek

Journal:

Bulletin des Sociétés Chimiques Belges

Year:

1995

Language:

english

File:

PDF, 315 KB

english, 1995

3

Synthesis of Some 4-Substituted 1-(4-Hydroxybutyl)Pyrazolo-[3,4-D]Pyrimidine Analogues of 9-(4-Hydroxybutyl)Guanine (HBG)

Mohamed L. Taha, Hassan B. Lazrek

Journal:

Bulletin des Sociétés Chimiques Belges

Year:

1995

Language:

english

File:

PDF, 445 KB

english, 1995

4

ChemInform Abstract: Synthesis of 5′-Ethynyl-2′-deoxynucleoside Analogues as Building Block for Antisense Oligonucleotide

Hassan B. Lazrek, Abdelalli Rochdi, Joachim W. Engels

Journal:

Year:

1999

File:

PDF, 25 KB

1999

5

ChemInform Abstract: Synthesis of Certain New 1,2,3-Triazole Acyclonucleosides via 1,3-Dipolar Cycloaddition.

Smaail Radi, Hassan B. Lazrek

Journal:

Year:

2002

File:

PDF, 29 KB

2002

6

Synthesis and Biological Activity of New 1,2,3-Triazole Acyclonucleosides Analogues of ACV.

Smaail Radi, Hassan B. Lazrek

Journal:

Year:

2002

File:

PDF, 29 KB

2002

7

Synthesis and Biological Activity of Some 4-Substituted 1-[1-(2,3-Dihydroxy-1-propoxy)methyl-1,2,3-triazol-(4&5)-ylmethyl] -1H-pyrazolo[3,4-d]pyrimidines.

Omar Moukha-chafiq, Mohamed Labd Taha, Hassan Bihi Lazrek, Jean-Jacques Vasseur, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq

Journal:

Year:

2003

File:

PDF, 83 KB

2003

8

Synthesis and Biological Activity of Some Unsaturated 6-Azauracil Acyclonucleosides.

Youssef Kabbaj, Hassan Bihi Lazrek, Jean Louis Barascut, Jean Louis Imbach

Journal:

Year:

2005

File:

PDF, 27 KB

2005

9

Lewis Acid—Doped Natural Phosphate: New Catalysts for the One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-one.

Hanane El Badaoui, Fathallaah Bazi, Soumia Tamani, Said Baoulaajaj, Mohamed Zahouily, Hassan B. Lazrek, Said Sebti

Journal:

Year:

2006

File:

PDF, 25 KB

2006

10

ChemInform Abstract: A Procedure for Facile Synthesis of Nucleosides Using N,O-Bistrimethylsilylacetamide in the Presence of Natural Phosphate Coated with Potassium Iodide.

Laila Baddi, Michael Smietana, Said Sebti, Jean-Jacques Vasseur, Hassan B. Lazrek

Journal:

Year:

2010

File:

PDF, 22 KB

2010

11

ChemInform Abstract: Straightforward Synthesis of Triazoloacyclonucleotide Phosphonates as Potential HCV Inhibitors.

Hanane Elayadi, Michael Smietana, Christophe Pannecouque, Pieter Leyssen, Johan Neyts, Jean-Jacques Vasseur, Hassan B. Lazrek

Journal:

Year:

2011

File:

PDF, 34 KB

2011

12

ChemInform Abstract: An Economical Synthesis of D- and L-Pyrimidine Arabino- and Ribonucleosides.

Hassan B. Lazrek, Driss Ouzebla, Abdesslem Faraj

Journal:

Year:

2011

File:

PDF, 37 KB

2011

13

Straightforward synthesis of triazoloacyclonucleotide phosphonates as potential HCV inhibitors

Hanane Elayadi, Michael Smietana, Christophe Pannecouque, Pieter Leyssen, Johan Neyts, Jean-Jacques Vasseur, Hassan B. Lazrek

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 808 KB

english, 2010

14

Synthesis of some acyclonucleosides with the alkylating chain of acyclovir

Omar Moukha-Chafiq, Mohamed Labd Taha, Hassan Bihi Lazrek, Jean-Louis Barascut, Jean-Louis Imbach

Journal:

Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry

Year:

2000

File:

PDF, 179 KB

2000

15

Synthesis and Biological Evaluation of Some α-[6-(1′-Carbamoylalkylthio)-1 H-Pyrazolo[3,4-D]Pyrimidin-4-yl]Thioalkylcarboxamide Acyclonucleosides

Moukha-Chafiq, Omar, Taha, Mohamed Labd, Mouna, Abdelmalek, Lazrek, Hassan Bihi, Vasseur, Jean-Jacques, Clercq, Erik De

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2007

Language:

english

File:

PDF, 286 KB

english, 2007

16

Synthesis and biological activity of some 4-substituted 1-[1-(2,3-dihydroxy-1-propoxy)methyl-1,2,3-triazol-(4 & 5)-ylmethyl]-1H-pyrazolo[3,4-d]pyrimidines

Omar Moukha-chafiq, Mohamed Labd Taha, Hassan Bihi Lazrek, Jean-Jacques Vasseur, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq

Journal:

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

17

Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents

Elayadi, Hanane, Smietana, Michael, Vasseur, Jean J., Balzarini, Jan, Lazrek, Hassan B.

Journal:

Archiv der Pharmazie

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

18

Synthesis and Antiviral Activity of Some C 2 -, C 4 -, and C 6 -Substituted Pyrazolo[3,4-D]Pyrimidine Acyclonucleosides with the Alkylating Chains of ACV, HBG, and ISO-DHPG

Moukha-chafiq, Omar, Taha, Mohamed Labd, Lazrek, Hassan Bihi, Vasseur, Jean-Jacques, Clercq, Erik De

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2006

Language:

english

File:

PDF, 289 KB

english, 2006

19

Benzimidazole-1,2,3-triazole Hybrid Molecules: Synthesis and Evaluation for Antibacterial/Antifungal Activity

Ouahrouch, Abdelaaziz, Ighachane, Hana, Taourirte, Moha, Engels, Joachim W., Sedra, My Hassan, Lazrek, Hassan B.

Journal:

Archiv der Pharmazie

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

20

Synthesis of 5′-Ethynyl-2′-deoxynucleoside Analogues as Building Block for Antisense Oligonucleotide

Lazrek, Hassan B., Rochdi, Abdelalli, Engels, Joachim W.

Journal:

Nucleosides and Nucleotides

Year:

1999

Language:

english

File:

PDF, 131 KB

english, 1999

21

Synthesis of Some Novel 1-(5-Thio-ß-D-glucopyranosyl)-6-azauracil Derivatives - Thiosugar Nucleosides

Al-Masoudi, Najim A., Pfleiderer, Wolfgang, Lazrek, Hassan B.

Journal:

Nucleosides and Nucleotides

Year:

1993

Language:

english

File:

PDF, 474 KB

english, 1993

22

AN ECONOMICAL SYNTHESIS OF D- AND L-PYRIMIDINE ARABINO- AND RIBONUCLEOSIDES

Lazrek, Hassan B., Ouzebla, Driss, Faraj, Abdesslem

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 318 KB

english, 2011

23

Synthesis and Biological Activity of Some Unsaturated 6-Azauracil Acyclonucleosides

Kabbaj, Youssef, Lazrek, Hassan Bihi, Barascut, Jean Louis, Imbach, Jean Louis

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2005

Language:

english

File:

PDF, 226 KB

english, 2005

24

Synthesis and Biological Activity of Some 5-Substituted-6-azauracil-N-1-Nucleosides of 2-Acetamido-2-Deoxy-D-glucose

Al-Masoudi, Najim A., Issa, Fadhel B., Pfleiderer, Wolgang, Lazrek, Hassan B.

Journal:

Nucleosides and Nucleotides

Year:

1995

Language:

english

File:

PDF, 462 KB

english, 1995

25

Synthesis of Novel Branched Nucleoside Dimers Containing a 1,2,3-Triazolyl Linkage

Lazrek, Hassan. B., Engels, Joaachim. W., Pfleiderer, Wolfgang

Journal:

Nucleosides and Nucleotides

Year:

1998

Language:

english

File:

PDF, 270 KB

english, 1998

26

Deacetylation Regioselective De Glycals

Bouhroum, Salah, Grondin, Joseph A., Houdier, Stephan, Lazrek, Hassan, Rhazi, Mohamed, Tolaimate, Abdelouahad, Vottéro, Philippe J.A.

Journal:

Journal of Carbohydrate Chemistry

Year:

1991

Language:

english

File:

PDF, 256 KB

english, 1991

27

Crystal structure of 2-benzamido- N -(2,2-diethoxyethyl)benzamide

Ouahrouch, Abdelaaziz, Taourirte, Moha, Lazrek, Hassan B., Engels, Joachim W., Bolte, Michael

Journal:

Acta Crystallographica Section E Crystallographic Communications

Year:

2015

Language:

english

File:

PDF, 366 KB

english, 2015

28

One-Pot Synthesis of Antiviral Acyclovir and Other Nucleosides Derivatives Using Doped Natural Phosphate as Lewis Acid Catalyst

Lazrek, Hassan B., Baddi, Laila, Smietana, Michael, Vasseur, Jean-Jacques, Sebti, Saïd, Zahouily, Mohamed

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2008

Language:

english

File:

PDF, 187 KB

english, 2008

29

CuSO 4 /KI As Catalyst for the Synthesis of 1,4-Disubstituted-1,2,3-Triazolo-Nucleosides

Elayadi, Hanane, Lazrek, Hassan Bihi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2015

Language:

english

File:

PDF, 304 KB

english, 2015

30

Four related diethyl [(arylamino)(4-ethynylphenyl)methyl]phosphonates

Ouahrouch, Abdelaaziz, Krim, Jamal, Taourirte, Moha, Lazrek, Hassan B., Engels, Joachim W., Bats, Jan W.

Journal:

Acta Crystallographica Section C Crystal Structure Communications

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

31

4-{4-[(4-Oxoquinazolin-3-yl)methyl]-1 H -1,2,3-triazol-1-yl}butyl acetate

Ouahrouch, Abdelaaziz, Taourirte, Moha, Lazrek, Hassan B., El Azhari, Mohamed, Saadi, Mohamed, El Ammari, Lahcen

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

32

Methyl 2-(3-chlorobenzamido)benzoate

Ouahrouch, Abdelaaziz, Taourirte, Moha, Lazrek, Hassan B., El Azhari, Mohamed, Saadi, Mohamed, El Ammari, Lahcen

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2012

Language:

english

File:

PDF, 359 KB

english, 2012

33

4-(4-{[(2-Phenylquinazolin-4-yl)oxy]methyl}-1 H -1,2,3-triazol-1-yl)butan-1-ol hemihydrate

Ouahrouch, Abdelaaziz, Lazrek, Hassan B., Taourirte, Moha, El Azhari, Mohamed, Saadi, Mohamed, El Ammari, Lahcen

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2011

Language:

english

File:

PDF, 582 KB

english, 2011

34

2-({4-[4-(1 H -Benzimidazol-2-yl)phenyl]-1 H -1,2,3-triazol-1-yl}methoxy)ethanol

Ouahrouch, Abdelaaziz, Taourirte, Moha, Lazrek, Hassan B., Bats, Jan W., Engels, Joachim W.

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

35

A New 1,2,4-Triazole Acyclonucleosides: Synthesis and Biological Evaluation

Radi, Smaail, Lazrek, Hassan

Journal:

Letters in Drug Design & Discovery

Year:

2007

Language:

english

File:

PDF, 28 KB

english, 2007

36

Synthesis and Biological Activity of Some Unsaturated 6-Azauracil Acyclonucleosides

Kabbaj, Youssef, Lazrek, Hassan Bihi, Barascut, Jean Louis, Imbach, Jean Louis

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2005

Language:

english

File:

PDF, 199 KB

english, 2005

37

Phosphates: New Generation of Liquid-Phase Heterogeneous Catalysts in Organic Chemistry

Sebti, Said, Zahouily, Mohamed, Lazrek, Hassan, Mayoral, Jose, Macquarrie, Duncan

Journal:

Current Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 534 KB

english, 2008

38

A Procedure for Facile Synthesis of Nucleosides Using N, O-Bistrimethylsilylacetamide in the Presence of Natural Phosphate Coated with Potassium Iodide

Baddi, Laila, Smietana, Michael, Sebti, Said, Vasseur, Jean-Jacques, B. Lazrek, Hassan

Journal:

Letters in Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 97 KB

english, 2010

39

Synthesis and biological activity of new 1,2,3-triazole acyclonucleosides analogues of ACV

Radi, Smaail, Lazrek, Hassan B.

Journal:

Journal of Chemical Research

Year:

2002

Language:

english

File:

PDF, 123 KB

english, 2002

40

Conformational analysis of oligoarabinonucleotides. An NMR and CD study

Doornbos, Johannes, Barascut, Jean-Louis, Lazrek, Hassan, Imbach, Jean-Louis, van Westrenen, Jeroen, Visser, Gerben M., van Boom, Jacques H., Altona, Cornelis

Journal:

Nucleic Acids Research

Year:

1983

Language:

english

File:

PDF, 723 KB

english, 1983

41

A One-Pot Synthesis of D-Ribonucleosides Using Natural Phosphate Doped with KI in HMDS

Lazrek, Hassan, Ouzebla, Driss, Rochdi, Abdellali, Redwane, Nezha, Vasseur, Jean-Jacques

Journal:

Letters in Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 25 KB

english, 2006

42

ChemInform Abstract: Synthesis of 1,2,3-Triazolyl Nucleoside Analogues as Potential Antiinfluenza A (H3N2 Subtype) Virus Agents.

Elayadi, Hanane, Smietana, Michael, Vasseur, Jean J., Balzarini, Jan, Lazrek, Hassan B.

Journal:

Year:

2014

File:

PDF, 21 KB

2014

43

ChemInform Abstract: CuSO 4 /KI as Catalyst for the Synthesis of 1,4-Disubstituted-1,2,3-triazolo-nucleosides.

Elayadi, Hanane, Lazrek, Hassan Bihi

Journal:

Year:

2015

File:

PDF, 18 KB

2015

44

Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3-Triazolylbenzyl-aminophosphonates

Ouahrouch, Abdelaaziz, Taourirte, Moha, Schols, Dominique, Snoeck, Robert, Andrei, Graciela, Engels, Joachim W., Lazrek, Hassan B.

Journal:

Archiv der Pharmazie

Year:

2016

Language:

english

File:

PDF, 953 KB

english, 2016

45

Synthesis of New 1,2,3-Triazol-4-yl-quinazoline Nucleoside and Acyclonucleoside Analogues

Ouahrouch, Abdelaaziz, Taourirte, Moha, Engels, Joachim, Benjelloun, Soumaya, Lazrek, Hassan

Journal:

Year:

2014

Language:

english

File:

PDF, 565 KB

english, 2014

46

Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes

Ighachane, Hana, Boualy, Brahim, Ait Ali, Mustapha, Sedra, My. H., El Firdoussi, Larbi, Lazrek, Hassan Bihi

Journal:

Advances in Materials Science and Engineering

Year:

2017

Language:

english

File:

PDF, 1.81 MB

english, 2017

47

1-[(2-Acetoxyethoxy)methyl]-3-ethyl-6-azauracil

Radi, Smaail, Lazrek, Hassan

Journal:

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000

48

1-[(2-Acetoxyethoxy)methyl]-3-ethoxycarbonylmethyl-5-bromo-6-azauracil

Radi, Smaail, Lazrek, Hassan

Journal:

Year:

2000

Language:

english

File:

PDF, 91 KB

english, 2000

49

1-[(2-Acetoxyethoxy)methyl]-3-allyl-5-bromo-6-azauracil

Radi, Smaail, Lazrek, Hassan

Journal:

Year:

2000

Language:

english

File:

PDF, 91 KB

english, 2000

50

1-[(2-Acetoxyethoxy)methyl]-3-benzyl-6-azauracil

Radi, Smaail, Lazrek, Hassan

Journal:

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000