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1

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

Chamieh, Hala, Ballut, Lionel, Bonneau, Fabien, Le Hir, Hervé

Journal:

Nature Structural and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 555 KB

english, 2007

2

The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity

Ballut, Lionel, Marchadier, Brice, Baguet, Aurélie, Tomasetto, Catherine, Séraphin, Bertrand, Le Hir, Hervé

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 487 KB

english, 2005

3

Insights into the design and interpretation of iCLIP experiments

Haberman, Nejc, Huppertz, Ina, Attig, Jan, König, Julian, Wang, Zhen, Hauer, Christian, Hentze, Matthias W., Kulozik, Andreas E., Le Hir, Hervé, Curk, Tomaž, Sibley, Christopher R., Zarnack, Kathi, Ul

Journal:

Year:

2017

Language:

english

File:

PDF, 2.75 MB

english, 2017

4

HTLV-1 Tax plugs and freezes UPF1 helicase leading to nonsense-mediated mRNA decay inhibition

Fiorini, Francesca, Robin, Jean-Philippe, Kanaan, Joanne, Borowiak, Malgorzata, Croquette, Vincent, Le Hir, Hervé, Jalinot, Pierre, Mocquet, Vincent

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.26 MB

english, 2018

5

A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner

Gowravaram, Manjeera, Bonneau, Fabien, Kanaan, Joanne, Maciej, Vincent D, Fiorini, Francesca, Raj, Saurabh, Croquette, Vincent, Le Hir, Hervé, Chakrabarti, Sutapa

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 5.14 MB

english, 2018

6

Erratum to: Insights into the design and interpretation of iCLIP experiments

Haberman, Nejc, Huppertz, Ina, Attig, Jan, König, Julian, Wang, Zhen, Hauer, Christian, Hentze, Matthias W., Kulozik, Andreas E., Le Hir, Hervé, Curk, Tomaž, Sibley, Christopher R., Zarnack, Kathi, Ul

Journal:

Year:

2017

Language:

english

File:

PDF, 222 KB

english, 2017

7

A Novel Rat Tyrosine Hydroxylase mRNA Species Generated by Alternative Splicing

Philippe Lanièce, Hervé Le Hir, Sylvie Bodeau-Péan, Yves Charon, Luc Valentin, Claude Thermes, Jacques Mallet, Sylvie Dumas

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 763 KB

english, 1996

8

New Species of Human Tyrosine Hydroxylase mRNA Are Produced in Variable Amounts in Adrenal Medulla and Are Overexpressed in Progressive Supranuclear Palsy

Sylvie Dumas, Hervé Le Hir, Sylvie Bodeau-Péan, Etienne Hirsch, Claude Thermes, Jacques Mallet

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 909 KB

english, 1996

9

A UPF3-mediated regulatory switch that maintains RNA surveillance

Chan, Wai-Kin, Bhalla, Angela D, Le Hir, Hervé, Nguyen, Lam Son, Huang, Lulu, Gécz, Jozef, Wilkinson, Miles F

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 458 KB

english, 2009

10

The exon junction complex differentially marks spliced junctions

Saulière, Jérôme, Haque, Nazmul, Harms, Scot, Barbosa, Isabelle, Blanchette, Marco, Le Hir, Hervé

Journal:

Nature Structural and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 417 KB

english, 2010

11

Expression of GFRα1 receptor splicing variants with different biochemical properties is modulated during kidney development

Nicolas Charlet-Berguerand, Hervé Le Hir, Mariarosaria Incoronato, Umberto di Porzio, Yanbin Yu, Shuqian Jing, Vittorio de Franciscis, Claude Thermes

Journal:

Cellular Signalling

Year:

2004

Language:

english

File:

PDF, 550 KB

english, 2004

12

Structural insights into the exon junction complex

Hervé Le Hir, Gregers Rom Andersen

Journal:

Current Opinion in Structural Biology

Year:

2008

Language:

english

File:

PDF, 1.32 MB

english, 2008

13

The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila

David Gatfield, Hervé Le Hir, Christel Schmitt, Isabelle C Braun, Thomas Köcher, Matthias Wilm, Elisa Izaurralde

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 250 KB

english, 2001

14

How introns influence and enhance eukaryotic gene expression

Hervé Le Hir, Ajit Nott, Melissa J. Moore

Journal:

Trends in Biochemical Sciences

Year:

2003

Language:

english

File:

PDF, 286 KB

english, 2003

15

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

Barbosa, Isabelle, Haque, Nazmul, Fiorini, Francesca, Barrandon, Charlotte, Tomasetto, Catherine, Blanchette, Marco, Le Hir, Hervé

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

16

CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex

Saulière, Jérôme, Murigneux, Valentine, Wang, Zhen, Marquenet, Emélie, Barbosa, Isabelle, Le Tonquèze, Olivier, Audic, Yann, Paillard, Luc, Crollius, Hugues Roest, Le Hir, Hervé

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1002 KB

english, 2012

17

EJCs at the Heart of Translational Control

Hervé Le Hir, Bertrand Séraphin

Journal:

Year:

2008

Language:

english

File:

PDF, 501 KB

english, 2008

18

Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and Its Regulation by Upf2

Sutapa Chakrabarti, Uma Jayachandran, Fabien Bonneau, Francesca Fiorini, Claire Basquin, Silvia Domcke, Hervé Le Hir, Elena Conti

Journal:

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

19

The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex

Murachelli, Andrea Giovanni, Ebert, Judith, Basquin, Claire, Le Hir, Hervé, Conti, Elena

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

20

Nonsense-mediated mRNA decay inhibition by HTLV-1 Tax protein

Mocquet, Vincent, Neusiedler, Julia, Rende, Francesca, Cluet, David, Robin, Jean-Philippe, Terme, Jean-Michel, Duc-Dodon, Madeleine, Morris, Christelle, Le Hir, Hervé, Ciminale, Vincenzo, Jalinot, Pie

Journal:

Year:

2014

Language:

english

File:

PDF, 76 KB

english, 2014

21

Transcriptome-wide identification of RNA binding sites by CLIP-seq

Murigneux, Valentine, Saulière, Jérôme, Roest Crollius, Hugues, Le Hir, Hervé

Journal:

Year:

2013

Language:

english

File:

PDF, 728 KB

english, 2013

22

RNA Helicases on the Move

Saurabh, Raj, Bagchi, Debjiani, Fiorini, Francesca, Le Hir, Hervé, Tanner, Kyle, Banroques, Josette, Croquette, Vincent

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 177 KB

english, 2014

23

5′-End RET Splicing: Absence of Variants in Normal Tissues and Intron Retention in Pheochromocytomas

Le Hir, Herv&eacute, , Charlet-Berguerand, Nicolas, de Franciscis, Vittorio, Thermes, Claude

Journal:

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

24

Transcriptome-wide modulation of splicing by the exon junction complex

Wang, Zhen, Murigneux, Valentine, Le Hir, Hervé

Journal:

Year:

2014

Language:

english

File:

PDF, 2.75 MB

english, 2014

25

Relative Expression of the RET9 and RET51 Isoforms in Human Pheochromocytomas

Le Hir, Herv&eacute, , Charlet-Berguerand, Nicolas, Gimenez-Roqueplo, Anne-Paule, Mannelli, Massimo, Plouin, Pierre-Fran&ccedil, ois, de Franciscis, Vittorio, Thermes, Claude

Journal:

Year:

2000

Language:

english

File:

PDF, 811 KB

english, 2000

26

Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities

Fiorini, Francesca, Bagchi, Debjani, Le Hir, Hervé, Croquette, Vincent

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.11 MB

english, 2015

27

The exon junction complex as a node of post-transcriptional networks

Hir, Hervé Le, Saulière, Jérôme, Wang, Zhen

Journal:

Nature Reviews Molecular Cell Biology

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

28

A Scale of Methodological Quality for Clinical Studies of Radiologic Examinations1

Arrivé, Lionel, Renard, Raphaëlle, Carrat, Fabrice, Belkacem, Ahcène, Dahan, Hervé, Le Hir, Pierre, Monnier-Cholley, Laurence, Tubiana, Jean-Michel

Journal:

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

29

Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex

Gretel Buchwald, Judith Ebert, Claire Basquin, Jerome Sauliere, Uma Jayachandran, Fulvia Bono, Hervé Le Hir, Elena Conti and John Kuriyan

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.68 MB

english, 2010

30

Upf1-Like Helicaes - Same Subfamily, Yet so Different Behavior

Raj, Saurabh, Kanaan, Joanne, Le Hir, Hervé, Croquette, Vincent

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 62 KB

english, 2017

31

A mechanistic study of helicases with magnetic traps

Hodeib, Samar, Raj, Saurabh, Manosas, M., Zhang, Weiting, Bagchi, Debjani, Ducos, Bertrand, Fiorini, Francesca, Kanaan, Joanne, Le Hir, Hervé, Allemand, Jean-François, Bensimon, David, Croquette, Vinc

Journal:

Protein Science

Year:

2017

Language:

english

File:

PDF, 2.96 MB

english, 2017

32

Exon Junction Complexes can have distinct functional flavours to regulate specific splicing events

Wang, Zhen, Ballut, Lionel, Barbosa, Isabelle, Le Hir, Hervé

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

33

UPF1-like helicase grip on nucleic acids dictates processivity

Kanaan, Joanne, Raj, Saurabh, Decourty, Laurence, Saveanu, Cosmin, Croquette, Vincent, Le Hir, Hervé

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 7.57 MB

english, 2018

34

Nonsense‐mediated mRNA decay involves two distinct Upf1‐bound complexes

Dehecq, Marine, Decourty, Laurence, Namane, Abdelkader, Proux, Caroline, Kanaan, Joanne, Le Hir, Hervé, Jacquier, Alain, Saveanu, Cosmin

Journal:

The EMBO Journal

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

35

Monitored eCLIP: high accuracy mapping of RNA-protein interactions

Hocq, Rémi, Paternina, Janio, Alasseur, Quentin, Genovesio, Auguste, Le Hir, Hervé

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

36

ALFA: annotation landscape for aligned reads

Bahin, Mathieu, Noël, Benoit F., Murigneux, Valentine, Bernard, Charles, Bastianelli, Leila, Le Hir, Hervé, Lebreton, Alice, Genovesio, Auguste

Journal:

Year:

2019

Language:

english

File:

PDF, 1.56 MB

english, 2019

37

ALFA: annotation landscape for aligned reads

Bahin, Mathieu, Noël, Benoit F., Murigneux, Valentine, Bernard, Charles, Bastianelli, Leila, Le Hir, Hervé, Lebreton, Alice, Genovesio, Auguste

Journal:

Year:

2019

File:

PDF, 1.56 MB

2019