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51

Identification of novel chromone based sulfonamides as highly potent and selective inhibitors of alkaline phosphatases

al-Rashida, Mariya, Raza, Rabia, Abbas, Ghulam, Shah, Muhammad Shakil, Kostakis, George E., Lecka, Joanna, Sévigny, Jean, Muddassar, Muhammad, Papatriantafyllopoulou, Constantina, Iqbal, Jamshed

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.93 MB

english, 2013

52

Diadenosine 5′,5′′-(Boranated)polyphosphonate Analogues as Selective Nucleotide Pyrophosphatase/Phosphodiesterase Inhibitors ⊥

Eliahu, Shay, Lecka, Joanna, Reiser, Georg, Haas, Michael, Bigonnesse, François, Lévesque, Sébastien A., Pelletier, Julie, Sévigny, Jean, Fischer, Bilha

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

53

Cloning and Characterization of Mouse Nucleoside Triphosphate Diphosphohydrolase-8 †,‡

Bigonnesse, François, Lévesque, Sébastien A., Kukulski, Filip, Lecka, Joanna, Robson, Simon C., Fernandes, Maria J. G., Sévigny, Jean

Journal:

Year:

2004

Language:

english

File:

PDF, 220 KB

english, 2004

54

Bone and fat: A relationship of different shades

Lecka-Czernik, Beata, Stechschulte, Lance A.

Journal:

Archives of Biochemistry and Biophysics

Year:

2014

Language:

english

File:

PDF, 532 KB

english, 2014

55

2-Hexylthio-β,γ-CH 2 -ATP is an Effective and Selective NTPDase2 Inhibitor

Gillerman, Irina, Lecka, Joanna, Simhaev, Luba, Munkonda, Mercedes N., Fausther, Michel, Martín-Satué, Mireia, Senderowitz, Hanoch, Sévigny, Jean, Fischer, Bilha

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 8.99 MB

english, 2014

56

Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone

Cheng, Y, Rodriguiz, R M, Murthy, S R K, Senatorov, V, Thouennon, E, Cawley, N X, Aryal, D K, Ahn, S, Lecka-Czernik, B, Wetsel, W C, Loh, Y P

Journal:

Molecular Psychiatry

Year:

2015

Language:

english

File:

PDF, 1.81 MB

english, 2015

57

Polyoxometalates—Potent and selective ecto-nucleotidase inhibitors

Lee, Sang-Yong, Fiene, Amelie, Li, Wenjin, Hanck, Theodor, Brylev, Konstantin A., Fedorov, Vladimir E., Lecka, Joanna, Haider, Ali, Pietzsch, Hans-Jürgen, Zimmermann, Herbert, Sévigny, Jean, Kortz, Ul

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 922 KB

english, 2015

58

Synthesis of Novel Phosphonic-Type Activity-Based Probes for Neutrophil Serine Proteases and Their Application in Spleen Lysates of Different Organisms

Grzywa, Renata, Burchacka, Ewa, Łęcka, Maria, Winiarski, Łukasz, Walczak, Maciej, Łupicka-Słowik, Agnieszka, Wysocka, Magdalena, Burster, Timo, Bobrek, Kamila, Csencsits-Smith, Keri, Lesner, Adam, Sie

Journal:

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

59

A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR- nuclear translocation

Kawai, M., Green, C. B., Lecka-Czernik, B., Douris, N., Gilbert, M. R., Kojima, S., Ackert-Bicknell, C., Garg, N., Horowitz, M. C., Adamo, M. L., Clemmons, D. R., Rosen, C. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 689 KB

english, 2010

60

High bone mass in adult mice with diet-induced obesity results from a combination of initial increase in bone mass followed by attenuation in bone formation; implications for high bone mass and decreased bone quality in obesity

Lecka-Czernik, B., Stechschulte, L.A., Czernik, P.J., Dowling, A.R.

Journal:

Molecular and Cellular Endocrinology

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

61

Generation and application of polyclonal IgY antibodies specific for full-length and nicked prostate-specific antigen

Łupicka-Słowik, Agnieszka, Walczak, Maciej, Grzywa, Renata, Bobrek, Kamila, Łęcka, Maria, Boivin, Stephane, Gaweł, Andrzej, Stefaniak, Tadeusz, Oleksyszyn, Józef, Sieńczyk, Marcin

Journal:

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

62

Thyroid hormone resistance syndrome due to mutations in the thyroid hormone receptor gene (THRA)

Tylki-Szymanska, A., Acuna-Hidalgo, R., Krajewska-Walasek, M., Lecka-Ambroziak, A., Steehouwer, M., Gilissen, C., Brunner, H. G., Jurecka, A., Rozdzynska-Swiatkowska, A., Hoischen, A., Chrzanowska, K.

Journal:

Journal of Medical Genetics

Year:

2015

Language:

english

File:

PDF, 671 KB

english, 2015

63

NTPDase1 Controls IL-8 Production by Human Neutrophils

Kukulski, F., Bahrami, F., Ben Yebdri, F., Lecka, J., Martin-Satue, M., Levesque, S. A., Sevigny, J.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 856 KB

english, 2011

64

Divergent Effects of Selective Peroxisome Proliferator-Activated Receptor-γ2 Ligands on Adipocyte Versus Osteoblast Differentiation

Lecka-Czernik, Beata, Moerman, Elena J., Grant, David F., Lehmann, Jürgen M., Manolagas, Stavros C., Jilka, Robert L.

Journal:

Year:

2002

Language:

english

File:

PDF, 456 KB

english, 2002

65

The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment

Ranganathan, G., Unal, R., Pokrovskaya, I., Yao-Borengasser, A., Phanavanh, B., Lecka-Czernik, B., Rasouli, N., Kern, P. A.

Journal:

The Journal of Lipid Research

Year:

2006

Language:

english

File:

PDF, 276 KB

english, 2006

66

Cloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8

Fausther, M., Lecka, J., Kukulski, F., Levesque, S. A., Pelletier, J., Zimmermann, H., Dranoff, J. A., Sevigny, J.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2006

Language:

english

File:

PDF, 589 KB

english, 2006

67

Bone Is a Target for the Antidiabetic Compound Rosiglitazone

Rzonca, S. O., Suva, L. J., Gaddy, D., Montague, D. C., Lecka-Czernik, B.

Journal:

Year:

2004

Language:

english

File:

PDF, 330 KB

english, 2004

68

Fluorescence polarization immunoassays for monitoring nucleoside triphosphate diphosphohydrolase (NTPDase) activity

Fiene, Amelie, Baqi, Younis, Lecka, Joanna, Sévigny, Jean, Müller, Christa E.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2015

Language:

english

File:

PDF, 602 KB

english, 2015

69

Extracellular Purine Metabolism in Blood Vessels (Part II): Activity of Ecto-Enzymes in Blood Vessels of Patients With Abdominal Aortic Aneurysm

Lecka, J., Bloch-Boguslawska, E., Molski, S., Komoszynski, M.

Journal:

Clinical and Applied Thrombosis/Hemostasis

Year:

2010

Language:

english

File:

PDF, 229 KB

english, 2010

70

Thiazolidinedione Use and Bone Loss in Older Diabetic Adults

Schwartz, Ann V., Sellmeyer, Deborah E., Vittinghoff, Eric, Palermo, Lisa, Lecka-Czernik, Beata, Feingold, Kenneth R., Strotmeyer, Elsa S., Resnick, Helaine E., Carbone, Laura, Beamer, Brock A., Park,

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 79 KB

english, 2006

71

8-BuS-ATP derivatives as specific NTPDase1 inhibitors

Lecka, Joanna, Gillerman, Irina, Fausther, Michel, Salem, Mabrouka, Munkonda, Mercedes N, Brosseau, Jean-Philippe, Cadot, Christine, Martín-Satué, Mireia, d'Orléans-Juste, Pedro, Rousseau, Éric, Poiri

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 37.03 MB

english, 2013

72

Adult Growth Hormone Replacement using a Fixed Graded Initiation Phase followed by an Individualised Titration Phase: A Single Centre Experience

Prague, J., Taylor, C., Al-Zaman, Y., Lecka, A., Oguntolu, V., Miell, J., McGregor, A., Aylwin, S.

Journal:

Hormone Research

Year:

2007

Language:

english

File:

PDF, 45 KB

english, 2007

73

Cellular and Molecular Biomarkers Indicate Precocious in vitro Senescence in Fibroblasts From SAMP6 Mice: Evidence Supporting a Murine Model of Premature Senescence and Osteopenia

Lecka-Czernik, B., Moerman, E. J., Reis, R. J. S., Lipschitz, D. A.

Journal:

The Journals of Gerontology Series A Biological Sciences and Medical Sciences

Year:

1997

Language:

english

File:

PDF, 839 KB

english, 1997

74

Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells

Bahrami, Fariborz, Kukulski, Filip, Lecka, Joanna, Tremblay, Alain, Pelletier, Julie, Rockenbach, Liliana, Sévigny, Jean

Journal:

Mediators of Inflammation

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

75

2 Regulates a Molecular Signature of Marrow Mesenchymal Stem Cells

Shockley, K. R., Rosen, C. J., Churchill, G. A., Lecka-Czernik, B.

Journal:

Year:

2007

Language:

english

File:

PDF, 227 KB

english, 2007

76

Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions

Ngo, Thang Ngoc, Ejaz, Syeda Abida, Hung, Tran Quang, Dang, Tuan Thanh, Iqbal, Jamshed, Lecka, Joanna, Sévigny, Jean, Langer, Peter

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 897 KB

english, 2015

77

Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1

Lecka, Joanna, Fausther, Michel, Künzli, Beat, Sévigny, Jean

Journal:

Mediators of Inflammation

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

78

Extracellular-Purine Metabolism in Blood Vessels (Part I). Extracellular-Purine Level in Blood of Patients with Abdominal Aortic Aneurysm

Lecka, Joanna, Molski, Stanislaw, Komoszynski, Michal

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2010

Language:

english

File:

PDF, 184 KB

english, 2010

79

Coexpression of ecto-5'-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver

Fausther, M., Lecka, J., Soliman, E., Kauffenstein, G., Pelletier, J., Sheung, N., Dranoff, J. A., Sevigny, J.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2012

Language:

english

File:

PDF, 5.66 MB

english, 2012

80

Synthesis and structure–activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists

Meltzer, Diana, Ethan, Ophir, Arguin, Guillaume, Nadel, Yael, Danino, Ortal, Lecka, Joanna, Sévigny, Jean, Gendron, Fernand-Pierre, Fischer, Bilha

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 587 KB

english, 2015

81

Investigation of quinoline-4-carboxylic acid as a highly potent scaffold for the development of alkaline phosphatase inhibitors: synthesis, SAR analysis and molecular modelling studies

Khan, Imtiaz, Shah, Syed Jawad Ali, Ejaz, Syeda Abida, Ibrar, Aliya, Hameed, Shahid, Lecka, Joanna, Millán, Jose Luis, Sévigny, Jean, Iqbal, Jamshed

Journal:

Year:

2015

Language:

english

File:

PDF, 1.60 MB

english, 2015

82

Skeletal integration of energy homeostasis: Translational implications

Lecka-Czernik, Beata, Rosen, Clifford J.

Journal:

Year:

2015

Language:

english

File:

PDF, 354 KB

english, 2015

83

Bone and diabetes (Sun Valley 2013)

Lecka-Czernik, Beata, Fowlkes, John

Journal:

Year:

2013

Language:

english

File:

PDF, 113 KB

english, 2013

84

Rosiglitazone Induces Decreases in Bone Mass and Strength that Are Reminiscent of Aged Bone

Lazarenko, Oxana P., Rzonca, Sylwia O., Hogue, William R., Swain, Frances L., Suva, Larry J., Lecka-Czernik, Beata

Journal:

Year:

2007

Language:

english

File:

PDF, 394 KB

english, 2007

85

PPARγ, an essential regulator of bone mass: Metabolic and molecular cues

Lecka-Czernik, Beata

Journal:

Year:

2010

Language:

english

File:

PDF, 274 KB

english, 2010

86

Orthopedic complications in diabetes

D. J. Gehling, B. Lecka-czernik, N. A. Ebraheim

Year:

2015

Language:

english

File:

PDF, 1.58 MB

english, 2015

87

Sweet and brittle — Diabetes mellitus and the skeleton

Hofbauer, Lorenz C., Lecka-Czernik, Beata, Seibel, Markus J.

Journal:

Year:

2015

Language:

english

File:

PDF, 157 KB

english, 2015

88

Synthesis, characterization and biological evaluation of N-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)benzamides

Iqbal, Jamshed, Saeed, Aamer, Ejaz, Syeda, Khurshid, Asma, Hassan, Sidra, al-Rashida, Mariya, Latif, Muhammad, Lecka, Joanna, sevigny, Jean

Journal:

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

89

Strain-Specific Effects of Rosiglitazone on Bone Mass, Body Composition, and Serum Insulin-Like Growth Factor-I

Ackert-Bicknell, Cheryl L., Shockley, Keith R., Horton, Lindsay G., Lecka-Czernik, Beata, Churchill, Gary A., Rosen, Clifford J.

Journal:

Year:

2009

Language:

english

File:

PDF, 343 KB

english, 2009

90

Diabetic Bone Disease ||

Lecka-Czernik, Beata, Fowlkes, John L.

Year:

2016

Language:

english

File:

PDF, 8.60 MB

english, 2016

91

Diabetic Bone Disease || Material Properties of Diabetic Bone

Lecka-Czernik, Beata, Fowlkes, John L.

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

92

Diabetic Bone Disease || Diabetes-Related Conditions and Complications in Orthopaedic Surgery

Lecka-Czernik, Beata, Fowlkes, John L.

Year:

2016

Language:

english

File:

PDF, 599 KB

english, 2016

93

Influence of the diversified structural variations at the imine functionality of 4-bromophenylacetic acid derived hydrazones on alkaline phosphatase inhibition: Synthesis and molecular modelling studies

Iqbal, Jamshed, Khan, Imtiaz, Ibrar, Aliya, Ejaz, Syeda, Khan, Shafi, Shah, Syed, Hameed, Shahid, Simpson, Jim, Lecka, Joanna, sevigny, Jean

Journal:

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

94

Activation of Peroxisome Proliferator-Activated Receptor γ (PPARγ) by Rosiglitazone Suppresses Components of the Insulin-Like Growth Factor Regulatory System in Vitro and in Vivo

Lecka-Czernik, B., Ackert-Bicknell, C., Adamo, M. L., Marmolejos, V., Churchill, G. A., Shockley, K. R., Reid, I. R., Grey, A., Rosen, C. J.

Journal:

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

95

Identification of Small Molecule Sulfonic Acids as Ecto-5'-Nucleotidase Inhibitors

Raza, Rabia, Saeed, Aamer, Lecka, Joanna, Sevigny, Jean, Iqbal, Jamshed

Journal:

Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 152 KB

english, 2012

96

A circadian-regulated gene,Nocturnin, promotes adipogenesis by stimulating PPAR-γ nuclear translocation

Masanobu Kawai, Carla B. Green, Beata Lecka-Czernik, Nicholas Douris, Misty R. Gilbert, Shihoko Kojima, Cheryl Ackert-Bicknell, Neha Garg, Mark C. Horowitz, Martin L. Adamo, David R. Clemmons, Cliffor

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

97

3-(5-(Benzylideneamino)thiozol-3-yl)-2H-chromen-2-ones: A new class of alkaline phosphatase and ecto-5′-nucleotidase inhibitors

Iqbal, Jamshed, Saeed, Aamer, Ejaz, Syeda, Shehzad, Muddasar, Hassan, Sidra, al-Rashida, Mariya, Sevigny, Jean, Lecka, Joanna

Journal:

Year:

2016

Language:

english

File:

PDF, 1.34 MB

english, 2016

98

2-Alkoxy-3-(sulfonylarylaminomethylene)-chroman-4-ones as potent and selective inhibitors of ectonucleotidases

Mariya al-Rashida,, Batool, Gazala, Sattar, Almas, Ejaz, Syeda Abida, Khan, Samiullah, Lecka, Joanna, Sévigny, Jean, Hameed, Abdul, Iqbal, Jamshed

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

99

Skeletal aging and the adipocyte program

Lecka-Czernik, Beata, Rosen, Clifford J., Kawai, Masanobu

Journal:

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

100

Energy Excess, Glucose Utilization, and Skeletal Remodeling: New Insights

Lecka-Czernik, Beata, Rosen, Clifford J

Journal:

Journal of Bone and Mineral Research

Year:

2015

Language:

english

File:

PDF, 504 KB

english, 2015