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51

A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C

Frederik Nevens, Tania Roskams, Hans Van Vlierberghe, Yves Horsmans, Drik Sprengers, Ann Elewaut, Valler Desmet, Geert Leroux-Roels, Emmanuel Quinaux, Erik Depla, Stephanie Dincq, Christine Vander Sti

Journal:

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

52

Combination of liquid-chromatography tandem mass spectrometry in different scan modes with human and chimeric mouse urine for the study of steroid metabolism

Oscar J. Pozo, Leen Lootens, Peter Van Eenoo, Koen Deventer, Philip Meuleman, Geert Leroux-Roels, Maria K. Parr, Wilhelm Schänzer, Frans T. Delbeke

Journal:

Drug Testing and Analysis

Year:

2009

Language:

english

File:

PDF, 319 KB

english, 2009

53

Steroid metabolism in chimeric mice with humanized liver

Leen Lootens, Peter Van Eenoo, Philip Meuleman, Oscar J. Pozo, Pieter Van Renterghem, Geert Leroux-Roels, Frans T. Delbeke

Journal:

Drug Testing and Analysis

Year:

2009

Language:

english

File:

PDF, 127 KB

english, 2009

54

The nucleocapsid of the hepatitis B virus: a remarkable immunogenic structure

Peter Vanlandschoot, Tinghua Cao, Geert Leroux-Roels

Journal:

Antiviral Research

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

55

Inhibition of replication of primary HIV-1 isolates in huPBL-NOD/Scid mice by antibodies from HIV-1 infected patients

Sophia Steyaert, Leo Heyndrickx, Lieven Verhoye, Tine Vermoesen, Helen Donners, Katrien Fransen, Filip Van Wanzeele, Beatrijs Vandergucht, Guido Vanham, Geert Leroux-Roels, Peter Vanlandschoot

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 1.08 MB

english, 2007

56

The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV

Philip Meuleman, Geert Leroux-Roels

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

57

The interferon gamma secretion assay: a reliable tool to study interferon gamma production at the single cell level

I Desombere, P Meuleman, H Rigole, A Willems, J Irsch, G Leroux-Roels

Journal:

Journal of Immunological Methods

Year:

2004

Language:

english

File:

PDF, 1.14 MB

english, 2004

58

The duration of in vitro stimulation with recall antigens determines the subset distribution of interferon-γ-producing lymphoid cells: A kinetic analysis using the Interferon-γ Secretion Assay™

I. Desombere, F. Clement, H. Rigole, G. Leroux-Roels

Journal:

Journal of Immunological Methods

Year:

2005

Language:

english

File:

PDF, 304 KB

english, 2005

59

The intraspleen huPBL NOD/SCID model to study the human HIV-specific antibody response selected in the course of natural infection

Sophia Steyaert, Lieven Verhoye, Els Beirnaert, Helen Donners, Katrien Fransen, Leo Heyndrickx, Guido Vanham, Geert Leroux-Roels, Peter Vanlandschoot

Journal:

Journal of Immunological Methods

Year:

2007

Language:

english

File:

PDF, 586 KB

english, 2007

60

Vaccine adjuvants

Garçon, Nathalie, Leroux-Roels, Geert, Cheng, Wen-Fang

Journal:

Perspectives in Vaccinology

Year:

2011

Language:

english

File:

PDF, 2.47 MB

english, 2011

61

Vaccine development

Leroux-Roels, Geert, Bonanni, Paolo, Tantawichien, Terapong, Zepp, Fred

Journal:

Perspectives in Vaccinology

Year:

2011

Language:

english

File:

PDF, 2.03 MB

english, 2011

62

Hepatitis C virus (HCV) genotype analysis in apparently healthy anti- HCV-positive Parisian blood donors

L. Stuyver, C. Fretz, C. A. Esquivel, A. Boudifa, D. Jaulmes, N. Azar, F. Lunel, G. Leroux-Roels, G. Maertens, J. J. Fournel

Journal:

Transfusion (Wiley)

Year:

1996

Language:

english

File:

PDF, 789 KB

english, 1996

63

Stimulation of erythropoietin production after controlled blood loss

J. Philippe, G. Leroux-Roels, M. De Buyzere, A. Weyne

Journal:

European Journal of Haematology

Year:

1992

Language:

english

File:

PDF, 117 KB

english, 1992

64

Influenza vaccines: T-cell responses deserve more attention

Schotsaert, Michael, Saelens, Xavier, Leroux-Roels, Geert

Journal:

Expert Review of Vaccines

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

65

Glycylprolyl-diaminopeptidase in human leukocytes: selective occurrence in T lymphocytes and influence on the total serum enzyme activity

Y. Kasahara, G. Leroux-Roels, R. Nakamura, F. Chisari

Journal:

Clinica Chimica Acta

Year:

1984

Language:

english

File:

PDF, 531 KB

english, 1984

66

Low serum creatine kinase in patients with infective endocarditis

Ivan K. De Scheerder, Joris R. Delanghe, Marc L. De Buyzere, Geert Hollanders, Denis L. Clement, Geert G. Leroux-Roels

Journal:

Clinica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 452 KB

english, 1991

67

Glycation of human tissue and serum creatine kinase

Michel R. Langlois, Joris R. Delanghe, Marc L. De Buyzere, Geert G. Leroux-Roels

Journal:

Clinica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 619 KB

english, 1992

68

Glomerular filtration rate and creatinine production in adult icteric patients

Joris R. Delanghe, Henk K. Louagie, Marc L. De Buyzere, Geert G. Leroux-Roels

Journal:

Clinica Chimica Acta

Year:

1994

Language:

english

File:

PDF, 837 KB

english, 1994

69

Genetic polymorphisms and erythrocyte sodium-lithium countertransport in essential hypertension

Kurt G. Tournoy, Joris R. Delanghe, Daniel A. Duprez, Marc L. De Buyzere, Ronald M. Verbeeck, Donald A. Vergauwe, Geert G. Leroux-Roels, Denis L. Clement

Journal:

Clinica Chimica Acta

Year:

1996

Language:

english

File:

PDF, 962 KB

english, 1996

70

Human hepatocytes secrete soluble CD14, a process not directly influenced by HBV and HCV infection

Philip Meuleman, Sophia Steyaert, Louis Libbrecht, Sibyl Couvent, Freya Van Houtte, Filip Clinckspoor, Bernard de Hemptinne, Tania Roskams, Peter Vanlandschoot, Geert Leroux-Roels

Journal:

Clinica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

71

Vaccine-induced HIV seropositivity: A problem on the rise

Eva Van Braeckel, Marguerite Koutsoukos, Patricia Bourguignon, Frédéric Clement, Lisa McNally, Geert Leroux-Roels

Journal:

Journal of Clinical Virology

Year:

2011

Language:

english

File:

PDF, 132 KB

english, 2011

72

Evidence for a relation between the viral load and genotype and hepatitis C virus-specific T cell responses

Catharina Hultgren, Isabelle Desombere, Geert Leroux-Roels, Juan A Quiroga, Vincente Carreno, Bo Nilsson, Ola Weiland, Matti Sällberg

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

73

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice

Thomas Vanwolleghem, Louis Libbrecht, Bettina E. Hansen, Isabelle Desombere, Tania Roskams, Philip Meuleman, Geert Leroux-Roels

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 1.61 MB

english, 2010

74

Metabolic studies with promagnon, methylclostebol and methasterone in the uPA+/+-SCID chimeric mice

L. Lootens, P. Meuleman, G. Leroux-Roels, P. Van Eenoo

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 869 KB

english, 2011

75

Expression, purification and characterization of full-length RNA-free hepatitis B core particles

Katleen Broos, Peter Vanlandschoot, Marleen Maras, Johan Robbens, Geert Leroux-Roels, Yves Guisez

Journal:

Protein Expression and Purification

Year:

2007

Language:

english

File:

PDF, 465 KB

english, 2007

76

Detection and structural investigation of metabolites of stanozolol in human urine by liquid chromatography tandem mass spectrometry

Oscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Susana Grimalt, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels, Frans T. Delbeke

Journal:

Year:

2008

Language:

english

File:

PDF, 2.22 MB

english, 2008

77

A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers

Geert Leroux-Roels, Erik Depla, Frank Hulstaert, Leen Tobback, Stéphanie Dincq, Jaques Desmet, Isabelle Desombere, Geert Maertens

Journal:

Year:

2004

Language:

english

File:

PDF, 138 KB

english, 2004

78

Potent enhancement of cellular and humoral immune responses against recombinant hepatitis B antigens using AS02A adjuvant in healthy adults

Pierre Vandepapelière, Barbara Rehermann, Marguerite Koutsoukos, Philippe Moris, Nathalie Garçon, Martine Wettendorff, Geert Leroux-Roels

Journal:

Year:

2005

Language:

english

File:

PDF, 1023 KB

english, 2005

79

Comparative pre-clinical and clinical experience with oral polio vaccine produced on MRC-5 cells or on primary monkey kidney cells

Viktor Prikazsky, Geert Leroux-Roels, Pierre Van Damme, Assad Safary, Brigitte Colau, Michel Duchene

Journal:

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

80

Long-term persistence of antibodies after one or two doses of MMR-vaccine

Corinne Vandermeulen, Roelants Mathieu, Leroux-Roels Geert, Van Damme Pierre, Hoppenbrouwers Karel

Journal:

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

81

Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: A randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudine

Pierre Vandepapelière, George K.K. Lau, Geert Leroux-Roels, Yves Horsmans, Edward Gane, Tawesak Tawandee, Mohd Ismail bin Merican, Khin Maung Win, Christian Trepo, Graham Cooksley, Martine Wettendorff

Journal:

Year:

2007

Language:

english

File:

PDF, 991 KB

english, 2007

82

Reduced detection and levels of protective antibodies to hepatitis B vaccine in under 2-year-old HIV positive South African children at a paediatric outpatient clinic

Omphile E. Simani, Geert Leroux-Roels, Guido François, Rosemary J. Burnett, André Meheus, M. Jeffrey Mphahlele

Journal:

Year:

2009

Language:

english

File:

PDF, 146 KB

english, 2009

83

Seasonal influenza vaccine delivered by intradermal microinjection: A randomised controlled safety and immunogenicity trial in adults

Isabel Leroux-Roels, Eva Vets, Ralf Freese, Michael Seiberling, Françoise Weber, Camille Salamand, Geert Leroux-Roels

Journal:

Year:

2008

Language:

english

File:

PDF, 575 KB

english, 2008

84

Humoral and cellular immune responses to split-virion H5N1 influenza vaccine in young and elderly adults

Isabel Leroux-Roels, Marie Van der Wielen, Froukje Kafeja, Corinne Vandermeulen, Rajeka Lazarus, Matthew D. Snape, Tessa John, Christophe Carre, Nolwenn Nougarede, Stephanie Pepin, Geert Leroux-Roels,

Journal:

Year:

2009

Language:

english

File:

PDF, 475 KB

english, 2009

85

Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: An open non-randomised extension of a double-blind randomised primary study

Isabel Leroux-Roels, François Roman, Sheron Forgus, Cathy Maes, Fien De Boever, Mamadou Dramé, Paul Gillard, Robbert van der Most, Marcelle Van Mechelen, Emmanuel Hanon, Geert Leroux-Roels

Journal:

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

86

Corrigendum to: “Seasonal influenza vaccine delivered by intradermal microinjection: A randomised controlled safety and immunogenicity trial in adults” by Leroux-Roels et al. [Vaccine 26 (2008) 6614–6619]

Isabel Leroux-Roels, Eva Vets, Ralf Freese, Michael Seiberling, Françoise Weber, Camille Salamand, Geert Leroux-Roels

Journal:

Year:

2010

Language:

english

File:

PDF, 80 KB

english, 2010

87

A randomized clinical trial to identify the optimal antigen and MF59® adjuvant dose of a monovalent A/H1N1 pandemic influenza vaccine in healthy adult and elderly subjects

Christoph Hatz, Frank von Sonnenburg, Daniela Casula, Maria Lattanzi, Geert Leroux-Roels

Journal:

Year:

2012

Language:

english

File:

PDF, 668 KB

english, 2012

88

A randomised, single-blind, dose-range study to assess the immunogenicity and safety of a cell-culture-derived A/H1N1 influenza vaccine in adult and elderly populations

Christoph Hatz, Jakob P. Cramer, André Vertruyen, Tino F. Schwarz, Frank von Sonnenburg, Astrid Borkowski, Maria Lattanzi, Anne Katrin Hilbert, Giovanni Della Cioppa, Geert Leroux-Roels

Journal:

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

89

Recombinant HBsAg, an apoptotic-like lipoprotein, interferes with the LPS-induced activation of ERK-1/2 and JNK-1/2 in monocytes

Peter Vanlandschoot, Annelies Roobrouck, Freya Van Houtte, Geert Leroux-Roels

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002

90

A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice

P. Meuleman, P. Vanlandschoot, G. Leroux-Roels

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

91

Hepatitis A booster vaccination: is there a need?

Pierre Van Damme, J Banatvala, O Fay, S Iwarson, B McMahon, K Van Herck, D Shouval, P Bonanni, B Connor, G Cooksley, G Leroux-Roels, F Von Sonnenburg

Journal:

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

92

Antifibrotic activity correlates with immune response to E1 therapeutic vaccination in 24 patients with chronic active hepatitis C

F. Nevens, T. Roskams, H. Van Vlierberghe, Y. Horsmans, D. Sprengers, A. Elewaut, V. Desmet, G. Leroux-Roels, E. Quinaux, E. Depla, S. Dincq, C. Vander Stichele, F. Hulstaert, G. Maertens

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 284 KB

english, 2003

93

101 HUMAN MONOCLONAL ANTIBODIES TARGETING SR-BI PREVENT HCV ENTRY AND VIRAL SPREAD IN VIVO

P. Meuleman, M.T. Catanese, L. Verhoye, I. Desombere, C.T. Jones, H. Walter, K. Grzyb, R. Cortese, C.M. Rice, G. Leroux-Roels, A. Nicosia

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 141 KB

english, 2011

94

827 EXPERIMENTAL HCV VACCINE COMBINING ADENOVIRUS AND PROTEIN ELICITS POTENT T-CELL RESPONSES AND NEUTRALIZING ANTIBODIES IN RODENTS

A. Chmielewska, M. Naddeo, V. Ammendola, K. Hu, L. Verhoye, R. Rappuoli, S. Colloca, A. Nicosia, R. Cortese, G. Leroux-Roels, P. Meuleman, K. Bienkowska-Szewczyk, P. Balfe, J.A. McKeating, A. Folgori

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

95

861 THE LECTIN GRIFFITHSIN HAS ANTIVIRAL ACTIVITY AGAINST HEPATITIS C VIRUS IN VITRO AND IN VIVO

P. Meuleman, A. Albecka, S. Belouzard, K. Vercauteren, L. Verhoye, C. Wychowski, G. Leroux-Roels, K.E. Palmer, J. Dubuisson

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 77 KB

english, 2012

96

A comparison of two commercial recombinant vaccines for hepatitis B in adolescents

Geert Leroux-Roels, Betsy Abraham, Marc Fourneau, N. De Clercq, Assad Safary

Journal:

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

97

Immune response of HLA DQ2 positive subjects, vaccinated with HBsAg/AS04, a hepatitis B vaccine with a novel adjuvant

Isabelle Desombere, Marie Van der Wielen, Pierre Van Damme, Michel Stoffel, Norbert De Clercq, Christian Goilav, Geert Leroux-Roels

Journal:

Year:

2002

Language:

english

File:

PDF, 54 KB

english, 2002

98

The immunogenicity and reactogenicity profile of a candidate hepatitis B vaccine in an adult vaccine non-responder population

P Jacques, G Moens, I Desombere, J Dewijngaert, G Leroux-Roels, M Wettendorff, S Thoelen

Journal:

Year:

2002

Language:

english

File:

PDF, 71 KB

english, 2002

99

Hepatitis B vaccine containing surface antigen and selected preS1 and preS2 sequences 2. Immunogenicity in poor responders to hepatitis B vaccines

Geert Leroux-Roels, Isabelle Desombere, Luc Cobbaut, Marie-Anne Petit, Pierre Desmons, Pierre Hauser, Andrée Delem, Danny De Grave, Assad Safary

Journal:

Year:

1997

Language:

english

File:

PDF, 693 KB

english, 1997

100

Hepatitis B vaccine containing surface antigen and selected preS1 and preS2 sequences. 1. Safety and immunogenicity in young, healthy adults

Geert Leroux-Roels, Isabelle Desombere, Guido De Tollenaere, Marie-Anne Petit, Pierre Desmons, Pierre Hauser, Andrée Delem, Danny De Grave, Assad Safary

Journal:

Year:

1997

Language:

english

File:

PDF, 1.07 MB

english, 1997