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1

Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity

Tiina M Asikainen, Ting-Ting Huang, Eero Taskinen, Anna-Liisa Levonen, Elaine Carlson, Risto Lapatto, Charles J Epstein, Kari O Raivio

Journal:

Free Radical Biology and Medicine

Year:

2002

Language:

english

File:

PDF, 496 KB

english, 2002

2

Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species

Paul S. Brookes, Anna-Liisa Levonen, Sruti Shiva, Paolo Sarti, Victor M. Darley-Usmar

Journal:

Free Radical Biology and Medicine

Year:

2002

Language:

english

File:

PDF, 332 KB

english, 2002

3

Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics

Levonen, Anna-Liisa, Hill, Bradford G., Kansanen, Emilia, Zhang, Jianhua, Darley-Usmar, Victor M.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 1.67 MB

english, 2014

4

Keap1 as the redox sensor of the antioxidant response

Sihvola, Virve, Levonen, Anna-Liisa

Journal:

Archives of Biochemistry and Biophysics

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

5

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

Cuadrado, Antonio, Rojo, Ana I., Wells, Geoffrey, Hayes, John D., Cousin, Sharon P., Rumsey, William L., Attucks, Otis C., Franklin, Stephen, Levonen, Anna-Liisa, Kensler, Thomas W., Dinkova-Kostova,

Journal:

Nature Reviews Drug Discovery

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

6

Ultrarotspektroskopie in der gerichtschemischen Analytik

Antti R. Alha, Veikko Tamminen, Anna -Liisa Mukula, Eeva Levonen, Aira Ruohonen, Eero Salomaa

Journal:

Archives of Toxicology

Year:

1960

Language:

german

File:

PDF, 737 KB

german, 1960

7

Generation and Biological Activities of Oxidized Phospholipids

Bochkov, Valery N., Oskolkova, Olga V., Birukov, Konstantin G., Levonen, Anna-Liisa, Binder, Christoph J., Stöckl, Johannes

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

8

Human glutamate cysteine ligase gene regulation through the electrophile response element

Dale A. Dickinson, Anna-Liisa Levonen, Douglas R. Moellering, Erin K. Arnold, Hongqiao Zhang, Victor M. Darley-Usmar, Henry Jay Forman

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 200 KB

english, 2004

9

Regulation of Nrf2-dependent gene expression by 15-deoxy-Δ12,14-prostaglandin J2

Emilia Kansanen, Annukka M. Kivelä, Anna-Liisa Levonen

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 776 KB

english, 2009

10

Antioxidant Response Element-Regulated Vectors for Cancer Gene Therapy

Hanna Leinonen, Seppo Ylä-Herttuala, Anna-Liisa Levonen

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 372 KB

english, 2010

11

Activation of Stress Signaling Pathways by Oxidized and Nitrated Lipids

Anna-Liisa Levonen

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 169 KB

english, 2010

12

Specific recognition of malondialdehyde and malondialdehyde acetaldehyde adducts on oxidized LDL and apoptotic cells by complement anaphylatoxin C3a

Marja Veneskoski, S. Pauliina Turunen, Outi Kummu, Antti Nissinen, Sirpa Rannikko, Anna-Liisa Levonen, Sohvi Hörkkö

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

13

Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells

Kati H. Pulkkinen, Seppo Ylä-Herttuala, Anna-Liisa Levonen

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

14

Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids

Emilia Kansanen, Henna-Kaisa Jyrkkänen, Anna-Liisa Levonen

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 959 KB

english, 2012

15

Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide

Suvi Rasilainen, Jenni M. Nieminen, Anna-Liisa Levonen, Timo Otonkoski, Risto Lapatto

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

16

Down-regulation of renal glutathione synthesis by systemic nitric oxide synthesis inhibition in spontaneously hypertensive rats

Anna-Liisa Levonen, Juha Laakso, Timo Vaskonen, Eero Mervaala, Heikki Karppanen, Risto Lapatto

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 205 KB

english, 2000

17

Mitochondria, nitric oxide, and cardiovascular dysfunction

Anup Ramachandran, Anna-Liisa Levonen, Paul S. Brookes, Erin Ceaser, Sruti Shiva, Maria Cecilia Barone, Victor Darley-Usmar

Journal:

Free Radical Biology and Medicine

Year:

2002

Language:

english

File:

PDF, 592 KB

english, 2002

18

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid

Katja Kanninen, Tarja M. Malm, Henna-Kaisa Jyrkkänen, Gundars Goldsteins, Velta Keksa-Goldsteine, Heikki Tanila, Masayuki Yamamoto, Seppo Ylä-Herttuala, Anna-Liisa Levonen, Jari Koistinaho

Journal:

Molecular and Cellular Neuroscience

Year:

2008

Language:

english

File:

PDF, 715 KB

english, 2008

19

Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products

LEVONEN, Anna-Liisa, LANDAR, Aimee, RAMACHANDRAN, Anup, CEASER, Erin K., DICKINSON, Dale A., ZANONI, Giuseppe, MORROW, Jason D., DARLEY-USMAR, Victor M.

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 349 KB

english, 2004

20

Analysis of gene and protein expression during monocyte-macrophage differentiation and cholesterol loading—cDNA and protein array study

Tiina T. Tuomisto, Mervi S. Riekkinen, Helena Viita, Anna-Liisa Levonen, Seppo Ylä-Herttuala

Journal:

Atherosclerosis

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

21

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

Annukka M. Kivelä, Petri I. Mäkinen, Henna-Kaisa Jyrkkänen, Eero Mella-Aho, Yifeng Xia, Emilia Kansanen, Hanna Leinonen, Inder M. Verma, Seppo Ylä-Herttuala, Anna-Liisa Levonen

Journal:

Atherosclerosis

Year:

2010

Language:

english

File:

PDF, 916 KB

english, 2010

22

Extracellular Superoxide Dismutase Accelerates Endothelial Recovery and Inhibits In-Stent Restenosis in Stented Atherosclerotic Watanabe Heritable Hyperlipidemic Rabbit Aorta

Jan Hinrich Bräsen, Olli Leppänen, Matias Inkala, Tommi Heikura, Max Levin, Fabian Ahrens, Juha Rutanen, Hubertus Pietsch, David Bergqvist, Anna-Liisa Levonen, Samar Basu, Thomas Zeller, Günter Klöppe

Journal:

Journal of the American College of Cardiology

Year:

2007

Language:

english

File:

PDF, 539 KB

english, 2007

23

Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A

Kivelä, Annukka M., Dijkstra, Marike H., Heinonen, Suvi E., Gurzeler, Erika, Jauhiainen, Suvi, Levonen, Anna-Liisa, Ylä-Herttuala, Seppo

Journal:

Atherosclerosis

Year:

2012

Language:

english

File:

PDF, 629 KB

english, 2012

24

Mechanisms of Cell Signaling by Nitric Oxide and Peroxynitrite: From Mitochondria to MAP Kinases

Levonen, Anna-Liisa, Patel, Rakesh P., Brookes, Paul, Go, Young-Mi, Jo, Hanjoong, Parthasarathy, Sampath, Anderson, Peter G., Darley-Usmar, Victor M.

Journal:

Antioxidants & Redox Signaling

Year:

2001

Language:

english

File:

PDF, 409 KB

english, 2001

25

Does Nrf2 Gene Transfer Facilitate Recovery After Contusion Spinal Cord Injury?

Pomeshchik, Yuriy, Kidin, Iurii, Savchenko, Ekaterina, Rolova, Taisia, Yamamoto, Masayuki, Levonen, Anna-Liisa, Ylä-Herttuala, Seppo, Malm, Tarja, Kanninen, Katja, Koistinaho, Jari

Journal:

Antioxidants & Redox Signaling

Year:

2014

Language:

english

File:

PDF, 958 KB

english, 2014

26

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

Kansanen, Emilia, Kuosmanen, Suvi M., Leinonen, Hanna, Levonen, Anna-Liisa

Journal:

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

27

Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity

Kärkkäinen, Virve, Pomeshchik, Yuriy, Savchenko, Ekaterina, Dhungana, Hiramani, Kurronen, Antti, Lehtonen, Sarka, Naumenko, Nikolay, Tavi, Pasi, Levonen, Anna-Liisa, Yamamoto, Masayuki, Malm, Tarja, M

Journal:

Year:

2014

Language:

english

File:

PDF, 2.57 MB

english, 2014

28

Mechanism for the protective effect of pyrrolidine dithiocarbamate against oxidative stress in AD: induction of the Nrf2-ARE pathway

Kanninen, Katja, Tarja, Malm, Giniatullina, Raisa, Crouch, Peter, Yamamoto, Masayuki, Giniatullin, Rashid, Goldsteins, Gundars, Levonen, Anna-Liisa, White, Anthony, Koistinaho, Jari

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 52 KB

english, 2011

29

HIF-1 Induction Attenuates Nrf2-Dependent IL-8 Expression in Human Endothelial Cells

Loboda, Agnieszka, Stachurska, Anna, Florczyk, Urszula, Rudnicka, Dominika, Jazwa, Agnieszka, Wegrzyn, Joanna, Kozakowska, Magdalena, Stalinska, Krystyna, Poellinger, Lorenz, Levonen, Anna–Liisa, Yla–

Journal:

Antioxidants & Redox Signaling

Year:

2009

Language:

english

File:

PDF, 50.34 MB

english, 2009

30

Cytochrome P450 2A5 Constitutive Expression and Induction by Heavy Metals Is Dependent on Redox-Sensitive Transcription Factor Nrf2 in Liver

Lämsä, Virpi, Levonen, Anna-Liisa, Leinonen, Hanna, Ylä-Herttuala, Seppo, Yamamoto, Masayuki, Hakkola, Jukka

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 4.64 MB

english, 2010

31

Nitro-Oleic Acid Regulates Endothelin Receptor B in Endothelial Cells via Transcription Factor Nrf2

Kansanen, Emilia, Ruotsalainen, Anna-Kaisa, Laitinen, Heidi, Kuosmanen, Suvi M, Levonen, Anna-Liisa

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 36 KB

english, 2014

32

Activation of stress signaling pathways by oxidized and nitrated lipids

Levonen, Anna-Liisa

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

33

23. Catheter-Mediated Local Intramural Delivery of AdEC-SOD Inhibits Oxidative Stress and Reduces In-Stent Neointima by Accelerating Endothelial Cell Recovery in WHHL Rabbits Displaying Complex Human-Like Atherosclerotic Lesions

Leppanen, Olli, Hinrich Brasen, Jan, Heikura, Tommi, Inkala, Matias, Ahrens, Fabian, Rutanen, Juha, Levonen, Anna-Liisa, Basu, Samar, Laukkanen, Mikko O., Yla-Herttuala, Seppo

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

34

Prostaglandin 15d-PGJ 2 Inhibits Androgen Receptor Signaling in Prostate Cancer Cells

Kaikkonen, Sanna, Paakinaho, Ville, Sutinen, Päivi, Levonen, Anna-Liisa, Palvimo, Jorma J.

Journal:

Molecular Endocrinology

Year:

2013

Language:

english

File:

PDF, 449 KB

english, 2013

35

Applications of the Keap1-Nrf2 system for gene and cell therapy

Kanninen, Katja M., Pomeshchik, Yuriy, Leinonen, Hanna, Malm, Tarja, Koistinaho, Jari, Levonen, Anna-Liisa

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

36

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

Liddell, Jeffrey R., Lehtonen, Sarka, Duncan, Clare, Keksa-Goldsteine, Velta, Levonen, Anna-Liisa, Goldsteins, Gundars, Malm, Tarja, White, Anthony R., Koistinaho, Jari, Kanninen, Katja M.

Journal:

Journal of Neuroinflammation

Year:

2016

Language:

english

File:

PDF, 2.53 MB

english, 2016

37

Human cystathionine γ-lyase: developmental and in vitro expression of two isoforms

LEVONEN, Anna-Liisa, LAPATTO, Risto, SAKSELA, Mika, RAIVIO, Kari O.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

38

Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress

MOELLERING, Douglas R., LEVONEN, Anna-Liisa, GO, Young-Mi, PATEL, Rakesh P., DICKINSON, Dale A., FORMAN, Henry Jay, DARLEY-USMAR, Victor M.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

39

Induction of the permeability transition and cytochrome c release by 15-deoxy-Δ 12,14 -prostaglandin J 2 in mitochondria

Landar, Aimee, Shiva, Sruti, Levonen, Anna-Liisa, Oh, Joo-Yeun, Zaragoza, Corinne, Johnson, Michelle S., Darley-Usmar, Victor M.

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 496 KB

english, 2006

40

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

Jyrkkänen, Henna-Kaisa, Kuosmanen, Suvi, Heinäniemi, Merja, Laitinen, Heidi, Kansanen, Emilia, Mella-Aho, Eero, Leinonen, Hanna, Ylä-Herttuala, Seppo, Levonen, Anna-Liisa

Journal:

Biochemical Journal

Year:

2011

Language:

english

File:

PDF, 705 KB

english, 2011

41

Human cystathionine γ-lyase: developmental and in vitro expression of two isoforms

LEVONEN, Anna-Liisa, LAPATTO, Risto, SAKSELA, Mika, RAIVIO, Kari O.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

42

Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress

MOELLERING, Douglas R., LEVONEN, Anna-Liisa, GO, Young-Mi, PATEL, Rakesh P., DICKINSON, Dale A., FORMAN, Henry Jay, DARLEY-USMAR, Victor M.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

43

Dysregulation of the Keap1–Nrf2 pathway in cancer: Figure 1

Leinonen, Hanna M., Kansanen, Emilia, Pölönen, Petri, Heinäniemi, Merja, Levonen, Anna-Liisa

Journal:

Biochemical Society Transactions

Year:

2015

Language:

english

File:

PDF, 286 KB

english, 2015

44

Hemin and Cobalt Protoporphyrin Inhibit NLRP3 Inflammasome Activation by Enhancing Autophagy: A Novel Mechanism of Inflammasome Regulation

Nurmi, Katariina, Kareinen, Ilona, Virkanen, Juhani, Rajamäki, Kristiina, Kouri, Vesa-Petteri, Vaali, Kirsi, Levonen, Anna-Liisa, Fyhrquist, Nanna, Matikainen, Sampsa, Kovanen, Petri T., Eklund, Kari

Journal:

Journal of Innate Immunity

Year:

2016

Language:

english

File:

PDF, 380 KB

english, 2016

45

Insights into the role of NRF2 in cancer provided by cancer genomics

Pölönen, Petri, Levonen, Anna-Liisa

Journal:

Current Opinion in Toxicology

Year:

2016

Language:

english

File:

PDF, 883 KB

english, 2016

46

Redox signalling: from nitric oxide to oxidized lipids.

Shiva, Sruti, Moellering, Doug, Ramachandran, Anup, Levonen, Anna-Liisa, Landar, Aimee, Venkatraman, Aparna, Ceaser, Erin, Ulasova, Elena, Crawford, Jack H, Brookes, Paul S, Patel, Rakesh P, Darley-Us

Journal:

Biochemical Society Symposium

Year:

2004

Language:

english

File:

PDF, 104 KB

english, 2004

47

Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

Frösen, Juhana, Tulamo, Riikka, Heikura, Tommi, Sammalkorpi, Sini, Niemelä, Mika, Hernesniemi, Juha, Levonen, Anna-Liisa, Hörkkö, Sohvi, Ylä-Herttuala, Seppo

Journal:

Acta Neuropathologica Communications

Year:

2013

Language:

english

File:

PDF, 1.68 MB

english, 2013

48

Nitro-oleic acid regulates endothelin signaling in human endothelial cells

Kansanen, Emilia, Kuosmanen, Suvi M, Ruotsalainen, Anna-Kaisa, Hynynen, Heidi, Levonen, Anna-Liisa

Journal:

Molecular Pharmacology

Year:

2017

Language:

english

File:

PDF, 652 KB

english, 2017

49

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells

Kuosmanen, Suvi M., Kansanen, Emilia, Sihvola, Virve, Levonen, Anna-Liisa

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.31 MB

english, 2017

50

Regulation of stress signaling pathways by nitro-fatty acids

Jawahar Deen, Ashik, Sihvola, Virve, Härkönen, Jouni, Patinen, Tommi, Adinolfi, Simone, Levonen, Anna-Liisa

Journal:

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

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