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51

Secretion of S-100 from rat C6 glioma cells

Linda J. Van Eldik, Danna B. Zimmer

Journal:

Year:

1987

Language:

english

File:

PDF, 441 KB

english, 1987

52

Neurotrophic activity of S-100β in cultures of dorsal root ganglia from embryonic chick and fetal rat

Linda J. Van Eldik, Barbara Christie-Pope, Laurel M. Bolin, Eric M. Shooter, William O. Whetsell Jr.

Journal:

Year:

1991

Language:

english

File:

PDF, 3.01 MB

english, 1991

53

Nuclear magnetic resonance assignments and secondary structure of bovine S100β protein

Peter M. Kilby, Linda J. Van Eldik, Gordon C.K. Roberts

Journal:

Year:

1995

Language:

english

File:

PDF, 736 KB

english, 1995

54

Multiple gene products are produced from a novel protein kinase transcription region

D Martin Watterson, Mark Collinge, Thomas J Lukas, Linda J Van Eldik, Konstantin G Birukov, Olga V Stepanova, Vladimir P Shirinsky

Journal:

Year:

1995

Language:

english

File:

PDF, 396 KB

english, 1995

55

Differential effects of oligomeric and fibrillar amyloid-β1–42 on astrocyte-mediated inflammation

Jill A. White, Arlene M. Manelli, Kristina H. Holmberg, Linda J. Van Eldik, Mary Jo LaDu

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 481 KB

english, 2005

56

Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo

Jeffrey M. Craft, D.Martin Watterson, Sally A. Frautschy, Linda J.Van Eldik

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 249 KB

english, 2004

57

Preclinical AD Workgroup staging: pathological correlates and potential challenges

Gregory A. Jicha, Erin L. Abner, Frederick A. Schmitt, Richard J. Kryscio, Kathryn P. Riley, Gregory E. Cooper, Nancy Stiles, Marta S. Mendiondo, Charles D. Smith, Linda J. Van Eldik, Peter T. Nelson

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 3.63 MB

english, 2012

58

Myosin light chain kinase (210 kDa) is a potential cytoskeleton integrator through its unique N-terminal domain

Dmitry S Kudryashov, Olga V Stepanova, Elena L Vilitkevich, Tatyana A Nikonenko, Elena S Nadezhdina, Nina A Shanina, Thomas J Lukas, Linda J Van Eldik, D.Martin Watterson, Vladimir P Shirinsky

Journal:

Experimental Cell Research

Year:

2004

Language:

english

File:

PDF, 787 KB

english, 2004

59

Unique sequence of a high molecular weight myosin light chain kinase is involved in interaction with actin cytoskeleton

Dmitry S. Kudryashov, Margarita V. Chibalina, Konstantin G. Birukov, Thomas J. Lukas, James R. Sellers, Linda J. Van Eldik, D.Martin Watterson, Vladimir P. Shirinsky

Journal:

Year:

1999

Language:

english

File:

PDF, 1.16 MB

english, 1999

60

Structure and enzymology of a death-associated protein kinase

Linda J Van Eldik

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

61

Transcriptional regulation of the human S100β gene

Francis Castets, W.Sue T Griffin, Alexander Marks, Linda J Van Eldik

Journal:

Molecular Brain Research

Year:

1997

Language:

english

File:

PDF, 292 KB

english, 1997

62

Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylation

Jin G. Sheng, Richard A. Jones, Xue Q. Zhou, John M. McGinness, Linda J. Van Eldik, Robert E. Mrak, W.Sue T. Griffin

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 709 KB

english, 2001

63

Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II

D.Martin Watterson, Salida Mirzoeva, Ling Guo, Authrine Whyte, Jean-Jacques Bourguignon, Marcel Hibert, Jacques Haiech, Linda J Van Eldik

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 189 KB

english, 2001

64

S100B proteins that lack one or both cysteine residues can induce inflammatory responses in astrocytes and microglia

Tanuja Koppal, Amy G.M Lam, Ling Guo, Linda J Van Eldik

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

65

Apolipoprotein E and apolipoprotein E receptors modulate Aβ-induced glial neuroinflammatory responses

Mary Jo LaDu, Javeed Ali Shah, Catherine A Reardon, Godfrey S Getz, Guojun Bu, Jingru Hu, Ling Guo, Linda J Van Eldik

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 554 KB

english, 2001

66

Glia and Alzheimer's disease

Linda J Van Eldik

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 52 KB

english, 2001

67

Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease

Elaine R Peskind, W.Sue T Griffin, Keith T Akama, Murray A Raskind, Linda J Van Eldik

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001

68

Molecular mechanisms and modulation of glial activation: Ligand modulation of biological responses mediated by gene-regulating protein kinases

Linda J. Van Eldik, D. Martin Watterson, Tanuja Koppal, Anu R. Sawkar, Salida Mirzoeva, M. Hibert, Jacques Haiech, J.-J. Bourguignon

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 375 KB

english, 2000

69

Apolipoprotein E and its receptors mediate the effects of β-amyloid-induced inflammation in primary astrocyte cultures

Mary Jo LaDu, Javeed Ali Shah, Catherine A. Reardon, Godfrey S. Getz, Guojun Bu, Jingru Hu, Linda J. Van Eldik

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 376 KB

english, 2000

70

Mechanism of glial activation by S100B: involvement of the transcription factor NFκB

Amy G.M Lam, Tanuja Koppal, Keith T Akama, Ling Guo, Jeffrey M Craft, Barat Samy, James P Schavocky, D Martin Watterson, Linda J Van Eldik

Journal:

Neurobiology of Aging

Year:

2001

Language:

english

File:

PDF, 158 KB

english, 2001

71

Similar activation of glial cultures from different rat brain regions by neuroinflammatory stimuli and downregulation of the activation by a new class of small molecule ligands

Ling Guo, Anu Sawkar, Magdalena Zasadzki, D.Martin Watterson, Linda J Van Eldik

Journal:

Neurobiology of Aging

Year:

2001

Language:

english

File:

PDF, 271 KB

english, 2001

72

Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1β production

Seon H. Kim, Carolyn J. Smith, Linda J. Van Eldik

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 315 KB

english, 2004

73

P1-434 Pyridazines as a new chemotype for Alzheimer's disease drug discovery targeting disease progression

Jeffrey M. Craft, Wenhui Hu, Linda J. Van Eldik, D. Martin Watterson

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 314 KB

english, 2004

74

Rapid separation and quantitation of 3′,5′-cyclic nucleotides and 5′-nucleotides in phosphodiesterase reaction mixtures using high-performance liquid chromatography

D.Martin Watterson, David B. Iverson, Linda J. Van Eldik

Journal:

Journal of Biochemical and Biophysical Methods

Year:

1980

Language:

english

File:

PDF, 620 KB

english, 1980

75

Development of a new class of orally bioavailable and safe experimental therapeutics that attenuate disease progression in an Alzheimer’s disease-related mouse model

Linda J. Van Eldik, Jeffrey M. Craft, Wenhui Hu, Hantamalala Ralay Ranaivo, D. Martin Watterson

Journal:

Alzheimer's & Dementia

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

76

O4-06-04: Intraneuronal Abeta42 aggregates seed amyloid plaques and cause neuronal loss in transgenic mice with five familial Alzheimer’s disease mutations

Robert Vassar, Holly Oakley, Sreemathi Logan, Erika Maus, Pei Shao, Jeffery Craft, Angela Guillozet-Bongaarts, Masuo Ohno, John Disterhoft, Linda Van Eldik, Robert Berry

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

77

P-014: Improving the CNS drug discovery process: Case study with an integrative approach yielding novel potential disease-modifying therapies

D.M. Watterson, Hantamalala Ralay Ranaivo, Heather Behanna, Saktimayee M. Roy, Laura K. Wing, Wenhui Hu, Lenka Munoz, Ling Guo, Laurie K. McNamara, Linda J. Van Eldik

Journal:

Alzheimer's & Dementia

Year:

2007

Language:

english

File:

PDF, 50 KB

english, 2007

78

S4-02-06: Integrative approach targeting neuroinflammation

Linda J. Van Eldik

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 49 KB

english, 2008

79

Cytokine Up-Regulation as a Contributor to CNS Pathophysiology

Linda Van Eldik

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 44 KB

english, 2011

80

COMPARATIVE BIOCHEMISTRY OF CALMODULINS AND CALMODULIN-LIKE PROTEINS

Linda J. Van Eldik, Gianni Pipemo, D. Martin Watterson

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 427 KB

english, 1980

81

ISOLATION OF A PROTEIN FROM BRAIN USING CALCIUM-DEPENDENT AFFINITY-BASED ADSORPTION CHROMATOGRAPHY ON PHENOTHIAZINE-SEPHAROSE CONJUGATES

Daniel R. Marshak, Linda J. Van Eldik, D. Martin Watterson

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 148 KB

english, 1980

82

REPRODUCIBLE PRODUCTION AND ANTISERA CHARACTERIZATION OF ANTI-CALMODULIN

Linda J. Van Eldik, D. Martin Watterson

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 94 KB

english, 1980

83

Isolation and characterization of the envelope glycoprotein of an avian osteopetrosis virus: Effect of host cell on antigenic reactivity

Linda J. Van Eldik, Ralph E. Smith

Journal:

Year:

1978

Language:

english

File:

PDF, 1.23 MB

english, 1978

84

Immunohistochemical localization of the S-100β protein in postnatal cat visual cortex: spatial and temporal patterns of expression in cortical and subcortical glia

Richard H. Dyck, Linda J. Van Eldik, Max S. Cynader

Journal:

Developmental Brain Research

Year:

1993

Language:

english

File:

PDF, 2.64 MB

english, 1993

85

Inhibition of protein kinase C- and casein kinase II-mediated phosphorylation of GAP-43 by S100β

Li-Hsien Lin, Linda J. Van Eldik, Neil Osheroff, Jeanette J. Norden

Journal:

Molecular Brain Research

Year:

1994

Language:

english

File:

PDF, 889 KB

english, 1994

86

Human brain S100β and S100β mRNA expression increases with age: Pathogenic implications for Alzheimer's disease

Jin G. Sheng, Robert E. Mrak, Cynthia R. Rovnaghi, Ewa Kozlowska, Linda J. Van Eldik, W.Sue T. Griffin

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 803 KB

english, 1996

87

In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis

Jin G. Sheng, Kazuhiro Ito, Robert D. Skinner, Robert E. Mrak, Cynthia R. Rovnaghi, Linda J. van Eldik, W.Sue T. Griffin

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 682 KB

english, 1996

88

Antisense Approaches to the Function of Glial Cell Proteins

LINDA J. VAN ELDIK, STEVEN W. BARGER, MICHAEL J. WELSH

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.79 MB

english, 1992

89

Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

Eric Lloyd, Kathleen Somera-Molina, Linda J Van Eldik, D Martin Watterson, Mark S Wainwright

Journal:

Journal of Neuroinflammation

Year:

2008

Language:

english

File:

PDF, 2.02 MB

english, 2008

90

Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human β-amyloid

Jeffrey M Craft, D Martin Watterson, Emmet Hirsch, Linda J Van Eldik

Journal:

Journal of Neuroinflammation

Year:

2005

Language:

english

File:

PDF, 957 KB

english, 2005

91

MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult

Wendy L Thompson, William J Karpus, Linda J Van Eldik

Journal:

Journal of Neuroinflammation

Year:

2008

Language:

english

File:

PDF, 2.64 MB

english, 2008

92

A novel p38α MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model

Lenka Munoz, Hantamalala Ralay Ranaivo, Saktimayee M Roy, Wenhui Hu, Jeffrey M Craft, Laurie K McNamara, Laura Wing Chico, Linda J Van Eldik, D Martin Watterson

Journal:

Journal of Neuroinflammation

Year:

2007

Language:

english

File:

PDF, 491 KB

english, 2007

93

Neuroinflammation: a potential therapeutic target

Craft, Jeffrey M, Watterson, D Martin, Van Eldik, Linda J

Journal:

Expert Opinion on Therapeutic Targets

Year:

2005

Language:

english

File:

PDF, 218 KB

english, 2005

94

Discovery of a 3-Amino-6-phenyl-pyridazine Derivative as a New Synthetic Antineuroinflammatory Compound

Mirzoeva, Salida, Sawkar, Anu, Zasadzki, Magdalena, Guo, Ling, Velentza, Anastasia V., Dunlap, Vincent, Bourguignon, Jean-Jacques, Ramstrom, Helena, Haiech, Jacques, Van Eldik, Linda J., Watterson, D.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

95

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

Scott J Webster, Adam D Bachstetter, Linda J Van Eldik

Journal:

Alzheimer's Research & Therapy

Year:

2013

Language:

english

File:

PDF, 990 KB

english, 2013

96

Beyond amyloid: Getting real about nonamyloid targets in Alzheimer's disease

Herrup, Karl, Carrillo, Maria C., Schenk, Dale, Cacace, Angela, DeSanti, Susan, Fremeau, Robert, Bhat, Ratan, Glicksman, Marcie, May, Patrick, Swerdlow, Russell, Van Eldik, Linda J., Bain, Lisa J., Bu

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 594 KB

english, 2013

97

Clinically relevant intronic splicing enhancer mutation in myelin proteolipid protein leads to progressive microglia and astrocyte activation in white and gray matter regions of the brain

Bachstetter, Adam D, Webster, Scott J, Van Eldik, Linda J, Cambi, Franca

Journal:

Journal of Neuroinflammation

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

98

Annotations.

Van Eldik, Linda J., Zimmer, Danna B.

Journal:

Year:

1881

Language:

english

File:

PDF, 885 KB

english, 1881

99

Approaches to Study the Role of S100 Proteins in Calcium-Dependent Cellular Responses

Van Eldik, Linda J., Zimmer, Danna B.

Journal:

Journal of Dairy Science

Year:

1988

Language:

english

File:

PDF, 675 KB

english, 1988

100

Notes from here and there

Jicha, Gregory, Panuganti, Pradeep, Abner, Erin, Nelson, Peter, Schmitt, Frederick, Kryscio, Richard, Van Eldik, Linda, Smith, Charles

Journal:

Journal of Endodontics

Year:

1986

Language:

english

File:

PDF, 171 KB

english, 1986

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