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51

Pre-clinical evaluation of a novel chloroethylating agent, Clomesone

Matthew, AM, Phillips, RM, Loadman, PM, Bibby, MC

Journal:

British Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 1.17 MB

english, 1993

52

Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours

Phillips, RM, Loadman, PM, Cronin, BP

Journal:

British Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 1.68 MB

english, 1998

53

5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: phase I clinical and pharmacokinetic study

Rustin, G J S, Bradley, C, Galbraith, S, Stratford, M, Loadman, P, Waller, S, Bellenger, K, Gumbrell, L, Folkes, L, Halbert, G

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 149 KB

english, 2003

54

Pharmacological approach towards the development of indolequinone bioreductive drugs based on the clinically inactive agent EO9

P M Loadman, M C Bibby, R M Phillips

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 190 KB

english, 2002

55

Neural regulation of rhythmic arm and leg movement is conserved across human locomotor tasks

E. Paul Zehr, Jaclyn E. Balter, Daniel P. Ferris, Sandra R. Hundza, Pamela M. Loadman, Rebecca H. Stoloff

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 730 KB

english, 2007

56

An automated system for mapping spatial movement patterns in behavioral research

Paul Niswander, William Loadman, Kaye Rasnake, John Wells

Journal:

Behavior Research Methods

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

57

Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent

Gary P. Wilkinson, James P. Taylor, Steve Shnyder, Patricia Cooper, Phil W. Howard, David E. Thurston, Terence C. Jenkins, Paul M. Loadman

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

58

Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity

Pors, Klaus, Loadman, Paul M., Shnyder, Steven D., Sutherland, Mark, Sheldrake, Helen M., Guino, Meritxell, Kiakos, Konstantinos, Hartley, John A., Searcey, Mark, Patterson, Laurence H.

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

59

The relationship between the in vitro chemosensitivity of tumor cells and tumor response in vivo in an experimental tumor model

Dr R. M. Phillips, M. C. Bibby, J. A. Double, P. M. Loadman

Journal:

Year:

1991

Language:

english

File:

PDF, 556 KB

english, 1991

60

Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs

Roger M. Phillips, Mohammed Jaffar, Derek J. Maitland, Paul M. Loadman, Steven D. Shnyder, Gillian Steans, Patricia A. Cooper, Amanda Race, Adam V. Patterson, Ian J. Stratford

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

61

Use of matrix-assisted laser desorption/ionisation mass spectrometry in cancer research

Hannah Bateson, Saira Saleem, Paul M. Loadman, Chris W. Sutton

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 837 KB

english, 2011

62

Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice

Paul M Loadman, Roger M Phillips, Lissa E Lim, Mike C Bibby

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 338 KB

english, 2000

63

The Deprived Child In Adoption

A. Evelyn Loadman, Kenneth N. McRae

Journal:

Developmental Medicine & Child Neurology

Year:

1977

Language:

english

File:

PDF, 685 KB

english, 1977

64

The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility

G Hawcroft, M Volpato, G Marston, N Ingram, SL Perry, AJ Cockbain, AD Race, A Munarini, A Belluzzi, PM Loadman, PL Coletta, MA Hull

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.30 MB

english, 2012

65

Formation of DNA interstrand cross-links as a marker of Mitomycin C bioreductive activation and chemosensitivity

Milène Volpato, Jill Seargent, Paul M. Loadman, Roger M. Phillips

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

66

Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: Correlation of MMP-14 mRNA expression and proteolytic activity

J.M. Atkinson, C.J. Pennington, S.W. Martin, V.A. Anikin, A.J. Mearns, P.M. Loadman, D.R. Edwards, J.H. Gill

Journal:

European Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 277 KB

english, 2007

67

Evaluation of the safety of C-1311 (SYMADEX) administered in a phase 1 dose escalation trial as a weekly infusion for 3 consecutive weeks in patients with advanced solid tumours

N. Isambert, M. Campone, E. Bourbouloux, M. Drouin, A. Major, W. Yin, P. Loadman, R. Capizzi, C. Grieshaber, P. Fumoleau

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 124 KB

english, 2010

68

Quantifying health status and functional outcomes following lung transplant

J.M L’Abbe, M Loadman Joyce, M.J Bentley, D.C Lien

Journal:

The Journal of Heart and Lung Transplantation

Year:

2004

Language:

english

File:

PDF, 67 KB

english, 2004

69

Predictive value of the 6-minute walk test in lung transplant outcomes

J L’Abbe, M Loadman Joyce, S Lau, M Bentley, D Lien

Journal:

The Journal of Heart and Lung Transplantation

Year:

2004

Language:

english

File:

PDF, 82 KB

english, 2004

70

216: Quality of Life and Functional Outcomes of Patients Undergoing Lung Transplantation for Pulmonary Fibrosis

D. Lien, M. Loadman, J. Holman, K. Jackson, J. Mullen, K. Stewart, D. Modry, K.-L. Visscher, J. Weinkauf

Journal:

The Journal of Heart and Lung Transplantation

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

71

376: Trends in the Functional Outcomes and Quality of Life of Cystic Fibrosis Patients following Lung Transplant

M. Loadman, J. Holman, K. Jackson, J. Weinkauf, N. Roland, A. Kapasi, D. Lien

Journal:

The Journal of Heart and Lung Transplantation

Year:

2010

Language:

english

File:

PDF, 115 KB

english, 2010

72

Expression of matrix metalloproteinase-10 in human bladder transitional cell carcinoma

Jill M. Seargent, Paul M. Loadman, Sandie W. Martin, Brian Naylor, Michael C. Bibby, Jason H. Gill

Journal:

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

73

Potential of AG in the treatment of breast cancer

J. Stanslas, P.S. Liew, N. Iftikhar, C.P. Lee, S. Saad, N. Lajis, R.A. Robins, P. Loadman, M.C. Bibby

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

74

UVB Radiation Affects Growth, Reproduction and Tissue Structure of Daphnia magna Across Several Temperatures

Judith D. Huebner, Nancy L. Loadman, Murray D. Wiegand, Erwin Huebner, Daniel J. Palitsky, William H. Husarewycz

Journal:

Photochemistry and Photobiology

Year:

2012

Language:

english

File:

PDF, 286 KB

english, 2012

75

Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study

Albertella, M. R., Loadman, P. M., Jones, P. H., Phillips, R. M., Rampling, R., Burnet, N., Alcock, C., Anthoney, A., Vjaters, E., Dunk, C. R., Harris, P. A., Wong, A., Lalani, A. S., Twelves, C. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 694 KB

english, 2008

76

Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation

Fournier-Dit-Chabert, Jérémie, Vinader, Victoria, Santos, Ana Rita, Redondo-Horcajo, Mariano, Dreneau, Aurore, Basak, Ramkrishna, Cosentino, Laura, Marston, Gemma, Abdel-Rahman, Hamdy, Loadman, Paul M

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 551 KB

english, 2012

77

500 Bioreductive activation and in vitro cytotoxicity of MUP03/704: a novel bioreductive cytotoxic drug conjugate for solid tumours

M. Volpato, P.M. Loadman, N. Abou Zeid, M. Jaffar, I.J. Stratford, R.M. Phillips

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 243 KB

english, 2004

78

312 POSTER Preclinical evaluation of a rationally designed novel class of non-hydroxamate Histone Deacetylase inhibitors (HDACi)

J.H. Gill, C.W.G. Fishwick, V. Androutsopoulos, A. Mohanarajah, T. Khamnaen, L.H. Patterson, S.D. Shnyder, P.M. Loadman, R. Grigg

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

79

417 POSTER Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) is overexpressed in lung cancer and can cleave peptide-conjugates

J. Atkinson, R. Falconer, C. Pennington, S. Martin, V. Anikin, A. Mearns, D. Edwards, L. Patterson, P. Loadman, J. Gill

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

80

Detection of NQO1 polymorphism in archived human bladder tumour tissue using PCR-RFLP: Predicting tumour response to mitomycin C

S. Basu, R.M. Phillips, P.M. Loadman, R. Puri, T. Shah, G.M. Flamigan, S.W. Martin, J.E. Brown

Journal:

European Urology Supplements

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

81

MATRIX METALLOPROTEINASE-9 EXPRESSION HELPS PREDICT RESPONSE TO INTRAVESICAL THERAPY IN CIS OF BLADDER

J. Cherian, A. Vodovnik, T. Shah, R. Puri, P. Loadman, R. Phillips

Journal:

European Urology Supplements

Year:

2006

Language:

english

File:

PDF, 52 KB

english, 2006

82

122 POSTER In silico modelling of doxorubicin penetration through multicell layers

R. Phillips, P. Loadman, P. Jones, S. Smye, C. Twelves, B. Sleeman, C. Evans

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 60 KB

english, 2008

83

24 INVITED The evolution of CYPs from metabolising enzymes to potential targets in cancer therapy development

L.H. Patterson, K. Pors, P.M. Loadman, M. Sutherland, J. Gill, H. Sheldrake, S.D. Shnyder

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

84

331 POSTER CYP1A1 activation and pharmacokinetics of a novel chloromethylpyrrollolindoline with potential as a tumour selective prodrug

A.D. Race, K. Pors, S.D. Shnyder, T.C. Cooper, H.M. Sheldrake, M. Searcey, L.H. Patterson, P.M. Loadman

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 84 KB

english, 2008

85

1202 In silico modelling of Doxorubicin penetration through multicell layers

R. Phillips, P.M. Loadman, C.J. Evans, P.F. Jones, S.W. Smye, B.D. Sleeman, C.J. Twelves

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

86

427 The development and evaluation of an experimental model for assessing convective fluid flow through multicell layers

R. Phillips, H. Makeen, N. Periasamy, P. Loadman, S. Smye, B. Sleeman, P. Jones, C. Evans, C. Twelves

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

87

Analysis of Rubber and Rubber-like Polymers || || Front_matter

Loadman, M. J. R.

Year:

1998

Language:

english

File:

PDF, 933 KB

english, 1998

88

Analysis of Rubber and Rubber-like Polymers || Instrumental polymer analysis

Loadman, M. J. R.

Year:

1998

Language:

english

File:

PDF, 4.16 MB

english, 1998

89

[IEEE 2008 6th Annual Communication Networks and Services Research Conference (CNSR '08) - Halifax, NS (2008.5.5-2008.5.8)] 6th Annual Communication Networks and Services Research Conference (cnsr 2008) - Experimental Study of the Retrodirective Antenna Array System in a Multipath Environment

Warrier, A., Zhizhang Chen,, Loadman, C.

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

90

Re-engineering of the Duocarmycin Structural Architecture Enables Bioprecursor Development Targeting CYP1A1 and CYP2W1 for Biological Activity

Sheldrake, Helen M., Travica, Sandra, Johansson, Inger, Loadman, Paul M., Sutherland, Mark, Elsalem, Lina, Illingworth, Nicola, Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven D., Mkrtchia

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 695 KB

english, 2013

91

Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex

Shnyder, Steve D., Fu, Ying, Habtemariam, Abraha, van Rijt, Sabine H., Cooper, Patricia A., Loadman, Paul M., Sadler, Peter J.

Journal:

Year:

2011

Language:

english

File:

PDF, 131 KB

english, 2011

92

Identification of Stage-Specific Breast Markers Using Quantitative Proteomics

Shaheed, Sadr-ul, Rustogi, Nitin, Scally, Andrew, Wilson, Julie, Thygesen, Helene, Loizidou, Maria A., Hadjisavvas, Andreas, Hanby, Andrew, Speirs, Valerie, Loadman, Paul, Linforth, Richard, Kyriacou,

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 1.71 MB

english, 2013

93

224 The Relationship Between the Anti-cancer Activity of the Omega-3 Polyunsaturated Fatty Acid Eicosapentaenoic Acid (EPA) and Colorectal Cancer Cell Migration

Volpato, M., Coletta, L., Loadman, P.M., Hull, M.A.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 62 KB

english, 2012

94

A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme (The seAFOod Polyp Prevention Trial): study protocol for a randomized controlled trial

Hull, Mark A, Sandell, Anna C, Montgomery, Alan A, Logan, Richard FA, Clifford, Gayle M, Rees, Colin J, Loadman, Paul M, Whitham, Diane

Journal:

Year:

2013

Language:

english

File:

PDF, 499 KB

english, 2013

95

Analysis of Rubber and Rubber-like Polymers ||

Loadman, M. J. R.

Year:

1998

Language:

english

File:

PDF, 933 KB

english, 1998

96

Effect of Eicosapentaenoic Acid on E-type Prostaglandin Synthesis and EP4 Receptor Signaling Human Colorectal Cancer Cells

Hawcroft, Gillian, Loadman, Paul M., Belluzzi, Andrea, Hull, Mark A.

Journal:

Year:

2010

Language:

english

File:

PDF, 954 KB

english, 2010

97

MMP-10 Is Overexpressed, Proteolytically Active, and a Potential Target for Therapeutic Intervention in Human Lung Carcinomas

Gill, Jason H., Kirwan, Ian G., Seargent, Jill M., Martin, Sandie W., Tijani, Sidiq, Anikin, Vladimir A., Mearns, Alan J., Bibby, Michael C., Anthoney, Alan, Loadman, Paul M.

Journal:

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

98

Potentiation of EO9 anti-tumour activity by hydralazine

Bibby, Michael C., Sleigh, N. Ruth, Loadman, Paul M., Double, John A.

Journal:

European Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 293 KB

english, 1993

99

Effects of routes of administration of TCNU on its plasma, tissue and tumour concentrations

Double, J.A., Bibby, M.C., Loadman, P.M., Bloomer, J.C.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1988

Language:

english

File:

PDF, 588 KB

english, 1988

100

Phase I/II Pilot Study of Intravesical Apaziquone (EO9) for Superficial Bladder Cancer

Puri, Rajiv, Palit, Victor, Loadman, Paul M., Flannigan, Michael, Shah, Tariq, Choudry, Guzanfar A., Basu, Saurajyoti, Double, John A., Lenaz, Gino, Chawla, Shanta, Beer, Mario, Van Kalken, Coen, de B

Journal:

The Journal of Urology

Year:

2006

Language:

english

File:

PDF, 318 KB

english, 2006