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101

Effect of pyruvate in cold cardioplegia on cardiac performance after prolonged ischemia in immature rabbit heart

Yoshikatsu Salki, Donna L. Panas, Gary D. Lopaschuk, Ivan M. Rebeyka

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

102

Insulin inhibition of 5′ adenosine monophosphate—activated protein kinase in the heart results in activation of acetyl coenzyme A carboxylase and inhibition of fatty acid oxidation

James Gamble, Gary D. Lopaschuk

Journal:

Year:

1997

Language:

english

File:

PDF, 581 KB

english, 1997

103

AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart

Nandakumar Sambandam, Gary D. Lopaschuk

Journal:

Progress in Lipid Research

Year:

2003

Language:

english

File:

PDF, 324 KB

english, 2003

104

Regulation of carbohydrate metabolism in ischemia and reperfusion

Journal:

American Heart Journal

Year:

2000

Language:

english

File:

PDF, 71 KB

english, 2000

105

The role of nitric oxide in cardiac depression induced by interleukin-1β and tumour necrosis factor-α

Richard Schulz, Donna L. Panas, Robert Catena, Salvador Moncada, Peter M. Olley, Gary D. Lopaschuk

Journal:

British Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.69 MB

english, 1995

106

Targeting mitochondrial oxidative metabolism as an approach to treat heart failure

Fillmore, Natasha, Lopaschuk, Gary D.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2013

Language:

english

File:

PDF, 522 KB

english, 2013

107

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

Keung, W., Ussher, J. R., Jaswal, J. S., Raubenheimer, M., Lam, V. H. M., Wagg, C. S., Lopaschuk, G. D.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

108

Cardiac Energy Metabolism in Obesity

Lopaschuk, G. D., Folmes, C. D.L., Stanley, W. C.

Journal:

Circulation Research

Year:

2007

Language:

english

File:

PDF, 491 KB

english, 2007

109

Alterations in energy metabolism in cardiomyopathies

Taha, Maysa, Lopaschuk, Gary D.

Journal:

Annals of Medicine

Year:

2007

Language:

english

File:

PDF, 364 KB

english, 2007

110

The anti-ischemic effect of trimetazidine in patients with postprandial myocardial ischemia is unrelated to meal composition

Gabriele Fragasso, Chiara Montano, Gianluca Perseghin, Altin Palloshi, Giliola Calori, Guido Lattuada, Silvia Oggionni, Giorgio Bassanelli, Massimo Locatelli, Gary Lopaschuk, Alberto Margonato

Journal:

American Heart Journal

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

111

ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance

Faye Borthwick, Samantha Warnakula, Rabban Mangat, Richard R. Uwiera, James C. Russell, Sandra E. Kelly, Candace Y. Lee, Larry Hryshko, John C.L. Mamo, Kerry-Anne Rye, Gary D. Lopaschuk, Spencer D. Pr

Journal:

Atherosclerosis

Year:

2012

Language:

english

File:

PDF, 1002 KB

english, 2012

112

CALMODULIN REGULATION OF CALCIUM TRANSPORT IN CARDIAC SARCOPLASMIC RETICULUM

Gary Lopaschuk, Sidney Katz

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 105 KB

english, 1980

113

Characterization of cardiac microsomal sarcoplasmic reticulum prepared from control and diabetic rats

Gary D. Lopaschuk, Sidney Katz, John H. McNeill

Journal:

Journal of Pharmacological Methods

Year:

1983

Language:

english

File:

PDF, 682 KB

english, 1983

114

Continuous long-term insulin delivery in diabetic rats utilizing implanted osmotic minipumps

Gary D. Lopaschuk, Arun G. Tahiliani, John H. McNeill

Journal:

Journal of Pharmacological Methods

Year:

1983

Language:

english

File:

PDF, 332 KB

english, 1983

115

Normal skeletal muscle metabolism during dynamic exercise to clinical fatigue and recovery: In vivo assessment by nuclear magnetic resonance spectroscopy

Roger Wong, Gary Lopaschuk, Norman Davies, Peter Allen, Gang Zhu, David Burton, Ruth Collins-Nakai, Terrence Montague

Journal:

Journal of the American College of Cardiology

Year:

1991

Language:

english

File:

PDF, 200 KB

english, 1991

116

Hypoxia-Induced Adaptation to Mitral Regurgitation: A Role for KATP Channel Up-Regulation?

Gary D. Lopaschuk, Jagdip S. Jaswal

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

117

Stimulation of myocardial CoA degradation by fatty acids

G.D. Lopaschuk, D.A. Berkich, J.R. Neely

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1984

Language:

english

File:

PDF, 80 KB

english, 1984

118

Insulin inhibits coenzyme a degradation in the diabetic rat heart

G.D. Lopaschuk, J.R. Neely

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1986

Language:

english

File:

PDF, 96 KB

english, 1986

119

Fatty acid metabolism in isolated working hearts from spontaneously diabetic “BB”wistar rats

G.D. Lopaschuk, H. Tsang

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1987

Language:

english

File:

PDF, 80 KB

english, 1987

120

Coenzyme a degradation in the heart: Effects of diabetes and insulin

G.D. Lopaschuk, J.R. Neely

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1987

Language:

english

File:

PDF, 546 KB

english, 1987

121

Dichloroacetate improves postischemic function of hypertrophied rat hearts

Richard B Wambolt, Gary D Lopaschuk, Roger W Brownsey, Michael F Allard

Journal:

Journal of the American College of Cardiology

Year:

2000

Language:

english

File:

PDF, 299 KB

english, 2000

122

High levels of fatty acids delay the recoveryof intracellular pH and cardiac efficiency inpost-ischemic hearts by inhibiting glucose oxidation

Que Liu, John C Docherty, John C.T Rendell, Alexander S Clanachan, Gary D Lopaschuk

Journal:

Journal of the American College of Cardiology

Year:

2002

Language:

english

File:

PDF, 187 KB

english, 2002

123

Volume overload hypertrophy of the newborn heart slows the maturation of enzymes involved in the regulation of fatty acid metabolism

Paul F Kantor, Murray A Robertson, James Y Coe, Gary D Lopaschuk

Journal:

Journal of the American College of Cardiology

Year:

1999

Language:

english

File:

PDF, 380 KB

english, 1999

124

Lack of increase in angiotensin II type 1 receptor protein after acute ischemia-reperfusion in isolated rat hearts

Yi Xu, Jason Dyck, Darryl W. O'Brien, William R. Ford, Alexander S. Clanachan, Garry D. Lopaschuk, Bodh I. Jugdutt

Journal:

Journal of Cardiac Failure

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

125

Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload

Zhabyeyev, P., Gandhi, M., Mori, J., Basu, R., Kassiri, Z., Clanachan, A., Lopaschuk, G. D., Oudit, G. Y.

Journal:

Cardiovascular Research

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

126

FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate

Piao, Lin, Sidhu, Vaninder K., Fang, Yong-Hu, Ryan, John J., Parikh, Kishan S., Hong, Zhigang, Toth, Peter T., Morrow, Erik, Kutty, Shelby, Lopaschuk, Gary D., Archer, Stephen L.

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

127

Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice

Dolinsky, Vernon W., Chakrabarti, Subhadeep, Pereira, Troy J., Oka, Tatsujiro, Levasseur, Jody, Beker, Donna, Zordoky, Beshay N., Morton, Jude S., Nagendran, Jeevan, Lopaschuk, Gary D., Davidge, Sandr

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 2.52 MB

english, 2013

128

Impact of the renin–angiotensin system on cardiac energy metabolism in heart failure

Mori, Jun, Zhang, Liyan, Oudit, Gavin Y., Lopaschuk, Gary D.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 704 KB

english, 2013

129

Hypothalamic malonyl-CoA and the control of food intake

Gao, Su, Moran, Timothy H., Lopaschuk, Gary D., Butler, Andrew A.

Journal:

Physiology & Behavior

Year:

2013

Language:

english

File:

PDF, 686 KB

english, 2013

130

Gut microbiota metabolism of l-carnitine and cardiovascular risk

Ussher, John R., Lopaschuk, Gary D., Arduini, Arduino

Journal:

Atherosclerosis

Year:

2013

Language:

english

File:

PDF, 639 KB

english, 2013

131

The Antianginal Drug Trimetazidine Shifts Cardiac Energy Metabolism From Fatty Acid Oxidation to Glucose Oxidation by Inhibiting Mitochondrial Long-Chain 3-Ketoacyl Coenzyme A Thiolase

Kantor, P. F., Lucien, A., Kozak, R., Lopaschuk, G. D.

Journal:

Circulation Research

Year:

2000

Language:

english

File:

PDF, 797 KB

english, 2000

132

Treatment with the 3-Ketoacyl-CoA Thiolase Inhibitor Trimetazidine Does Not Exacerbate Whole-Body Insulin Resistance in Obese Mice

Ussher, J. R., Keung, W., Fillmore, N., Koves, T. R., Mori, J., Zhang, L., Lopaschuk, D. G., Ilkayeva, O. R., Wagg, C. S., Jaswal, J. S., Muoio, D. M., Lopaschuk, G. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 4.24 MB

english, 2014

133

Mode of Action of Trimetazidine and Other New Metabolic Agents in the Treatment of Ischemic Heart Disease

Lopaschuk, G. D., Marzilli, M.

Journal:

Seminars in Cardiothoracic and Vascular Anesthesia

Year:

2003

Language:

english

File:

PDF, 1.10 MB

english, 2003

134

Angiotensin 1-7 Ameliorates Diabetic Cardiomyopathy and Diastolic Dysfunction in db/db Mice by Reducing Lipotoxicity and Inflammation

Mori, J., Patel, V. B., Abo Alrob, O., Basu, R., Altamimi, T., DesAulniers, J., Wagg, C. S., Kassiri, Z., Lopaschuk, G. D., Oudit, G. Y.

Journal:

Circulation Heart Failure

Year:

2014

Language:

english

File:

PDF, 6.79 MB

english, 2014

135

Cardiovascular remodelling in coronary artery disease and heart failure

Heusch, Gerd, Libby, Peter, Gersh, Bernard, Yellon, Derek, Böhm, Michael, Lopaschuk, Gary, Opie, Lionel

Journal:

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

136

5′-AMP-activated protein kinase increases glucose uptake independent of GLUT4 translocation in cardiac myocytes

Lee, Christopher T., Ussher, John R., Mohammad, Askar, Lam, Anna, Lopaschuk, Gary D.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 541 KB

english, 2014

137

EMPLOYMENT PROBLEMS OF HANDICAPPED YOUTH

Lopaschuk, Gary D., Eibschutz, Barry, Katz, Sidney, McNeill, John H.

Journal:

Year:

1960

Language:

english

File:

PDF, 182 KB

english, 1960

138

Depression of calcium transport in sarcoplasmic reticulum from diabetic rats: Lack of involvement by specific regulatory mediators

Lopaschuk, Gary D., Eibschutz, Barry, Katz, Sidney, McNeill, John H.

Journal:

General Pharmacology: The Vascular System

Year:

1984

Language:

english

File:

PDF, 466 KB

english, 1984

139

Regulating Cardiac Energy Metabolism and Bioenergetics by Targeting the DNA Damage Repair Protein BRCA1

Singh, K., Shukla, P., Quan, A., Lovren, F., Pan, Y., Wagg, C., Teoh, H., Lopaschuk, G., Verma, S.

Journal:

Canadian Journal of Cardiology

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

140

Regulating cardiac energy metabolism and bioenergetics by targeting the DNA damage repair protein BRCA1

Singh, Krishna K., Shukla, Praphulla C., Yanagawa, Bobby, Quan, Adrian, Lovren, Fina, Pan, Yi, Wagg, Cory S., Teoh, Hwee, Lopaschuk, Gary D., Verma, Subodh

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

141

Trimetazidine Therapy Prevents Obesity-Induced Cardiomyopathy in Mice

Ussher, John R., Fillmore, Natasha, Keung, Wendy, Mori, Jun, Beker, Donna L., Wagg, Cory S., Jaswal, Jagdip S., Lopaschuk, Gary D.

Journal:

Canadian Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 495 KB

english, 2014

142

Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei

Gao, Su, Casals, Núria, Keung, Wendy, Moran, Timothy H., Lopaschuk, Gary D.

Journal:

Physiology & Behavior

Year:

2013

Language:

english

File:

PDF, 2.29 MB

english, 2013

143

Effect of insulin treatment on long-term diabetes-induced alteration of myocardial function

Tahiliani, Arun G., Lopaschuk, Gary D., McNeill, John H.

Journal:

General Pharmacology: The Vascular System

Year:

1984

Language:

english

File:

PDF, 266 KB

english, 1984

144

Metabolic Inflexibility of Malonyl CoA Decarboxylase (MCD) Knockout Mice Leads to Cardiac Remodelling and High Mortality During Peri-Weaning Period

Aksentijevic, Dunja, Medway, Debra J., Sebag-Montefiore, Liam, Zervou, Sevasti, Douglas, Gillian, Lopaschuk, Gary D., Neubauer, Stefan, Lygate, Craig A.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

145

CHRONIC INHIBITION OF PYRUVATE DEHYDROGENASE KINASE WITH DICHLOROACETATE, IMPROVES CARDIAC METABOLISM AND FUNCTION IN RIGHT VENTRICULAR HYPERTROPHY IN FAWN-HOODED RATS

Piao, Lin, Sidhu, Vaninder K., Fang, Yong-Hu, Thenappan, Thenappan, Lopaschuk, Gary, Archer, Stephen

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 90 KB

english, 2012

146

Something Old Holds Potential to Be Something New in Heart Failure: Allopurinol Revisited

Jaswal, Jagdip S., Ussher, John R., Lopaschuk, Gary D., Johnstone, David E.

Journal:

Canadian Journal of Cardiology

Year:

2012

Language:

english

File:

PDF, 434 KB

english, 2012

147

CARDIAC HYPERTROPHY IN HUMAN NEWBORNS WITH CONGENITAL HEART DISEASE MODIFIES MATURATIONAL CHANGES IN CARDIAC ENERGY METABOLISM AND NEGATIVELY AFFECTS POSTSURGICAL FUNCTIONAL RECOVERY.

Huai, Alda, Jaswal, Jay, Lam, Victoria, Rebeyka, Ivan R., Lopaschuk, Gary D.

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 146 KB

english, 2013

148

Introduction to JMCC Symposium on Myocardial Energy Metabolism in Health and Disease

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 45 KB

english, 2002

149

Glycolysis and glucose oxidation during reperfusion of ischemic hearts from diabetic rats

Gamble, James, Lopaschuk, Gary D.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1994

Language:

english

File:

PDF, 919 KB

english, 1994

150

Cardiac Insulin-Resistance and Decreased Mitochondrial Energy Production Precede the Development of Systolic Heart Failure After Pressure-Overload Hypertrophy

Zhang, L., Jaswal, J. S., Ussher, J. R., Sankaralingam, S., Wagg, C., Zaugg, M., Lopaschuk, G. D.

Journal:

Circulation Heart Failure

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013