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51

Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities

Femke Baeke, Evelyne van Etten, Conny Gysemans, Lut Overbergh, Chantal Mathieu

Journal:

Molecular Aspects of Medicine

Year:

2008

Language:

english

File:

PDF, 239 KB

english, 2008

52

Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice

I. Dewachter, R.K. Filipkowski, C. Priller, L. Ris, J. Neyton, S. Croes, D. Terwel, M. Gysemans, H. Devijver, P. Borghgraef, E. Godaux, L. Kaczmarek, J. Herms, F. Van Leuven

Journal:

Neurobiology of Aging

Year:

2009

Language:

english

File:

PDF, 1.55 MB

english, 2009

53

Role of CD4+ and CD8+ T cells in the rejection of heart or islet xenografts in recipients with xenotolerance in the innate immune compartment

T. Devos, Y. Yan, C. Segers, O. Rutgeerts, J. Laureys, C. Gysemans, C. Mathieu, M. Waer

Journal:

Transplantation Proceedings

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

54

Immunomodulatory properties of a 1,25(OH)2 vitamin D3 analog combined with IFNβ in an animal model of syngeneic islet transplantation

E van Etten, C Gysemans, A Verstuyf, R Bouillon, C Mathieu

Journal:

Transplantation Proceedings

Year:

2001

Language:

english

File:

PDF, 61 KB

english, 2001

55

Leflunomide and its analogue X920715 synergize with cyclosporin A in preventing early graft failure and delaying graft rejection of xenogeneic islets in nonobese diabetic mice

C Gysemans, M Waer, J Laureys, R Bouillon, C Mathieu

Journal:

Transplantation Proceedings

Year:

2001

Language:

english

File:

PDF, 62 KB

english, 2001

56

A combination of KH1060, a vitamin D3 analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice

C Gysemans, M Waer, J Laureys, R Bouillon, C Mathieu

Journal:

Transplantation Proceedings

Year:

2001

Language:

english

File:

PDF, 62 KB

english, 2001

57

Seasonality of birth in patients with type 1 diabetes

Chantal Mathieu, Evelyne van Etten, Conny Gysemans, Brigitte Decallonne, Roger Bouillon

Journal:

Year:

2002

Language:

english

File:

PDF, 52 KB

english, 2002

58

Extraskeletal Effects of Vitamin D

Heidi Wolden-Kirk, Conny Gysemans, Annemieke Verstuyf, Chantal Mathieu

Journal:

Endocrinology and Metabolism Clinics of North America

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

59

1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism

Hannelie Korf, Mathias Wenes, Benoit Stijlemans, Tatiana Takiishi, Sofie Robert, Michela Miani, Decio L. Eizirik, Conny Gysemans, Chantal Mathieu

Journal:

Year:

2012

Language:

english

File:

PDF, 957 KB

english, 2012

60

P2-037: Modelling of differential phosphorylation, conformation and aggregation of protein tau in yeast is extended to its binding to microtubuli in vitro

Tom Vandebroek, Dick Terwel, Maarten Gysemans, Thomas Vanhelmont, Chris Van Haesendonck, Yves Engelborghs, Joris Winderickx, Fred Van Leuven

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

61

Vitamin D and Diabetes

Takiishi, Tatiana, Gysemans, Conny, Bouillon, Roger, Mathieu, Chantal

Journal:

Endocrinology and Metabolism Clinics of North America

Year:

2010

Language:

english

File:

PDF, 310 KB

english, 2010

62

Antigen-based vs. systemic immunomodulation in type 1 diabetes

Robert, Sofie, Korf, Hannelie, Gysemans, Conny, Mathieu, Chantal

Journal:

Year:

2013

Language:

english

File:

PDF, 993 KB

english, 2013

63

Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes

Overbergh, Lut, Gysemans, Conny, Mathieu, Chantal

Journal:

Expert Review of Molecular Diagnostics

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

64

Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population

Laoui, D., Van Overmeire, E., Di Conza, G., Aldeni, C., Keirsse, J., Morias, Y., Movahedi, K., Houbracken, I., Schouppe, E., Elkrim, Y., Karroum, O., Jordan, B., Carmeliet, P., Gysemans, C., De Baetse

Journal:

Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

65

1,25-Dihydroxyvitamin D3 Promotes Tolerogenic Dendritic Cells with Functional Migratory Properties in NOD Mice

Ferreira, G. B., Gysemans, C. A., Demengeot, J., da Cunha, J. P. M. C. M., Vanherwegen, A.-S., Overbergh, L., Van Belle, T. L., Pauwels, F., Verstuyf, A., Korf, H., Mathieu, C.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

66

Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD8 + T-cell activation events

Schouppe, Elio, Mommer, Camille, Movahedi, Kiavash, Laoui, Damya, Morias, Yannick, Gysemans, Conny, Luyckx, Ariane, De Baetselier, Patrick, Van Ginderachter, Jo A.

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

67

Unraveling the effects of 1,25(OH)2D3 on global gene expression in pancreatic islets

Wolden-Kirk, H., Overbergh, L., Gysemans, C., Brusgaard, K., Naamane, N., Van Lommel, L., Schuit, F., Eizirik, D.L., Christesen, H., Mathieu, C.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

68

SPECT-imaging of 5-HT2 receptors in depression

D'Haenen, H, Bossuyt-Piron, C, Mertens, J, Gysemans, M, Bossuyt, A

Journal:

European Neuropsychopharmacology

Year:

1991

Language:

english

File:

PDF, 47 KB

english, 1991

69

Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and -cell protection

Christensen, D. P., Gysemans, C., Lundh, M., Dahllof, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C. T., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 862 KB

english, 2014

70

Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis Reverses Diabetes in Recent-Onset NOD Mice

Robert, S., Gysemans, C., Takiishi, T., Korf, H., Spagnuolo, I., Sebastiani, G., Van Huynegem, K., Steidler, L., Caluwaerts, S., Demetter, P., Wasserfall, C. H., Atkinson, M. A., Dotta, F., Rottiers,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

71

Effects of vitamin D on antigen-specific and non-antigen-specific immune modulation: relevance for type 1 diabetes

Takiishi, Tatiana, Van Belle, Tom, Gysemans, Conny, Mathieu, Chantal

Journal:

Pediatric Diabetes

Year:

2013

Language:

english

File:

PDF, 748 KB

english, 2013

72

β -Cell differentiation and regeneration in type 1 diabetes

Ding, L., Gysemans, C., Mathieu, C.

Journal:

Diabetes, Obesity and Metabolism

Year:

2013

Language:

english

File:

PDF, 489 KB

english, 2013

73

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

Movahedi, K., Laoui, D., Gysemans, C., Baeten, M., Stange, G., Van den Bossche, J., Mack, M., Pipeleers, D., In't Veld, P., De Baetselier, P., Van Ginderachter, J. A.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

74

Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation

Gurzov, E N, Barthson, J, Marhfour, I, Ortis, F, Naamane, N, Igoillo-Esteve, M, Gysemans, C, Mathieu, C, Kitajima, S, Marchetti, P, Ørntoft, T F, Bakiri, L, Wagner, E F, Eizirik, D L

Journal:

Year:

2012

Language:

english

File:

PDF, 715 KB

english, 2012

75

Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas

Van Gassen, Naomi, Van Overmeire, Eva, Leuckx, Gunter, Heremans, Yves, De Groef, Sofie, Cai, Ying, Elkrim, Yvon, Gysemans, Conny, Stijlemans, Benoît, Van de Casteele, Mark, De Baetselier, Patrick, De

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 2.23 MB

english, 2015

76

Lung structure-function correlation in patients with primary ciliary dyskinesia

Boon, M., Vermeulen, F. L., Gysemans, W., Proesmans, M., Jorissen, M., De Boeck, K.

Journal:

Year:

2015

Language:

english

File:

PDF, 762 KB

english, 2015

77

The Vitamin D Analog, TX527, Promotes a Human CD4+CD25highCD127low Regulatory T Cell Profile and Induces a Migratory Signature Specific for Homing to Sites of Inflammation

Baeke, F., Korf, H., Overbergh, L., Verstuyf, A., Thorrez, L., Van Lommel, L., Waer, M., Schuit, F., Gysemans, C., Mathieu, C.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 983 KB

english, 2011

78

Unaltered Diabetes Presentation in NOD Mice Lacking the Vitamin D Receptor

Gysemans, C., van Etten, E., Overbergh, L., Giulietti, A., Eelen, G., Waer, M., Verstuyf, A., Bouillon, R., Mathieu, C.

Journal:

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

79

Disruption of the -Interferon Signaling Pathway at the Level of Signal Transducer and Activator of Transcription-1 Prevents Immune Destruction of -cells

Gysemans, C. A., Ladriere, L., Callewaert, H., Rasschaert, J., Flamez, D., Levy, D. E., Matthys, P., Eizirik, D. L., Mathieu, C.

Journal:

Year:

2005

Language:

english

File:

PDF, 315 KB

english, 2005

80

Cytokines Tumor Necrosis Factor- and Interferon- Induce Pancreatic -Cell Apoptosis through STAT1-mediated Bim Protein Activation

Barthson, J., Germano, C. M., Moore, F., Maida, A., Drucker, D. J., Marchetti, P., Gysemans, C., Mathieu, C., Nunez, G., Jurisicova, A., Eizirik, D. L., Gurzov, E. N.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.65 MB

english, 2011

81

Dietary Supplementation With High Doses of Regular Vitamin D3 Safely Reduces Diabetes Incidence in NOD Mice When Given Early and Long Term

Takiishi, T., Ding, L., Baeke, F., Spagnuolo, I., Sebastiani, G., Laureys, J., Verstuyf, A., Carmeliet, G., Dotta, F., Van Belle, T. L., Gysemans, C. A., Mathieu, C.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

82

Proteomics Analysis of Cytokine-induced Dysfunction and Death in Insulin-producing INS-1E Cells: New Insights into the Pathways Involved

D'Hertog, W., Overbergh, L., Lage, K., Ferreira, G. B., Maris, M., Gysemans, C., Flamez, D., Cardozo, A. K., Van den Bergh, G., Schoofs, L., Arckens, L., Moreau, Y., Hansen, D. A., Eizirik, D. L., Wae

Journal:

Molecular & Cellular Proteomics

Year:

2007

Language:

english

File:

PDF, 723 KB

english, 2007

83

Microtubule Binding and Clustering of Human Tau-4R and Tau-P301L Proteins Isolated from Yeast Deficient in Orthologues of Glycogen Synthase Kinase-3beta or cdk5

Vandebroek, T., Terwel, D., Vanhelmont, T., Gysemans, M., Van Haesendonck, C., Engelborghs, Y., Winderickx, J., Van Leuven, F.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 490 KB

english, 2006

84

Sex difference in resistance to dexamethasone-induced apoptosis in NOD mice: treatment with 1,25(OH)2D3 restores defect

Casteels, K. M., Gysemans, C. A., Waer, M., Bouillon, R., Laureys, J. M., Depovere, J., Mathieu, C.

Journal:

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

85

Leaching and migration of Np, Pu, and Am from α-doped SON68 HLW glass in contact with dense clay

Valcke, Elie, Gysemans, Mireille, Moors, Hugo, Van Iseghem, Pierre, Godon, Nicole, Jollivet, Patrick

Journal:

MRS Proceedings

Year:

2006

Language:

english

File:

PDF, 171 KB

english, 2006

86

Pancreatic Duct Cells in Human Islet Cell Preparations Are a Source of Angiogenic Cytokines Interleukin-8 and Vascular Endothelial Growth Factor

Movahedi, B., Gysemans, C., Jacobs-Tulleneers-Thevissen, D., Mathieu, C., Pipeleers, D.

Journal:

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

87

Deletion of STAT-1 Pancreatic Islets Protects Against Streptozotocin-Induced Diabetes and Early Graft Failure but Not Against Late Rejection

Callewaert, H. I., Gysemans, C. A., Ladriere, L., D'Hertog, W., Hagenbrock, J., Overbergh, L., Eizirik, D. L., Mathieu, C.

Journal:

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

88

The Use of Intermittent Lighting in Broiler Raising.: 2. Effects on the Somatotrophic and Thyroid Axes and on Plasma Testosterone Levels

Kuhn, E. R., Darras, V. M., Gysemans, C., Decuypere, E., Berghman, L. R., Buyse, J.

Journal:

Poultry Science

Year:

1996

Language:

english

File:

PDF, 662 KB

english, 1996

89

The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages

Daniel, B., Nagy, G., Hah, N., Horvath, A., Czimmerer, Z., Poliska, S., Gyuris, T., Keirsse, J., Gysemans, C., Van Ginderachter, J. A., Balint, B. L., Evans, R. M., Barta, E., Nagy, L.

Journal:

Genes & Development

Year:

2014

Language:

english

File:

PDF, 2.24 MB

english, 2014

90

Protective role of IFN- in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production

Kelchtermans, H., Struyf, S., De Klerck, B., Mitera, T., Alen, M., Geboes, L., Van Balen, M., Dillen, C., Put, W., Gysemans, C., Billiau, A., Van Damme, J., Matthys, P.

Journal:

Journal of Leukocyte Biology

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

91

Calcium Insufficiency Accelerates Type 1 Diabetes in Vitamin D Receptor-Deficient Nonobese Diabetic (NOD) Mice

Driver, John P., Lamont, Deanna J., Gysemans, Conny, Mathieu, Chantal, Serreze, David V.

Journal:

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

92

Double-Stranded RNA Induces Pancreatic -Cell Apoptosis by Activation of the Toll-Like Receptor 3 and Interferon Regulatory Factor 3 Pathways

Dogusan, Z., Garcia, M., Flamez, D., Alexopoulou, L., Goldman, M., Gysemans, C., Mathieu, C., Libert, C., Eizirik, D. L., Rasschaert, J.

Journal:

Year:

2008

Language:

english

File:

PDF, 406 KB

english, 2008

93

Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts

Gysemans, C. A., Waer, M., Valckx, D., Laureys, J. M., Mihkalsky, D., Bouillon, R., Mathieu, C.

Journal:

Year:

2000

Language:

english

File:

PDF, 81 KB

english, 2000

94

Toll-like Receptor 3 and STAT-1 Contribute to Double-stranded RNA+ Interferon- -induced Apoptosis in Primary Pancreatic -Cells

Rasschaert, J., Ladriere, L., Urbain, M., Dogusan, Z., Katabua, B., Sato, S., Akira, S., Gysemans, C., Mathieu, C., Eizirik, D. L.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 860 KB

english, 2005

95

Increased -Cell Mass by Islet Transplantation and PLAG1 Overexpression Causes Hyperinsulinemic Normoglycemia and Hepatic Insulin Resistance in Mice

Declercq, J., Kumar, A., Van Diepen, J. A., Vroegrijk, I. O. C. M., Gysemans, C., Di Pietro, C., Voshol, P. J., Mathieu, C., Ectors, N., Van de Ven, W. J. M., Verfaillie, C. M.

Journal:

Year:

2010

Language:

english

File:

PDF, 603 KB

english, 2010

96

Vitamin D || Vitamin D and Diabetes

Gysemans, Conny

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

97

Mechanism and Potential of the Growth-Inhibitory Actions of Vitamin D and Analogs

G. Eelen, Bentham Science Publisher, C. Gysemans, Bentham Science Publisher, L. Verlinden, Bentham Science Publisher, E. Vanoirbeek, Bentham Science Publisher, P. De Clercq, Bentham Science Publisher,

Journal:

Current Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

98

Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation

Eelen, G., Verlinden, L., Maes, C., Beullens, I., Gysemans, C., Paik, J.-H., DePinho, R.A., Bouillon, R., Carmeliet, G., Verstuyf, A.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 4.82 MB

english, 2015

99

Prospectively Isolated NGN3-Expressing Progenitors From Human Embryonic Stem Cells Give Rise to Pancreatic Endocrine Cells

Cai, Q., Bonfanti, P., Sambathkumar, R., Vanuytsel, K., Vanhove, J., Gysemans, C., Debiec-Rychter, M., Raitano, S., Heimberg, H., Ordovas, L., Verfaillie, C. M.

Journal:

Stem Cells Translational Medicine

Year:

2014

Language:

english

File:

PDF, 2.60 MB

english, 2014

100

1,25-Dihydroxyvitamin D3 Modulates Expression of Chemokines and Cytokines in Pancreatic Islets: Implications for Prevention of Diabetes in Nonobese Diabetic Mice

Gysemans, Conny A., Cardozo, Alessandra K., Callewaert, Hanne, Giulietti, Annapaula, Hulshagen, Leen, Bouillon, Roger, Eizirik, Décio L., Mathieu, Chantal

Journal:

Year:

2005

Language:

english

File:

PDF, 384 KB

english, 2005