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51

Isolation of the Embryonic Form of Smooth Muscle Myosin Heavy Chain (SMemb/NMHC-B) Gene and Characterization of Its 5′-Flanking Region

Ichiro Manabe, Masahiko Kurabayashi, Yukio Shimomura, Makoto Kuro-o, Noboru Watanabe, Masafumi Watanabe, Masanori Aikawa, Toru Suzuki, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 1.58 MB

english, 1997

52

Identification of the HumanKlothoGene and Its Two Transcripts Encoding Membrane and SecretedKlothoProtein

Yutaka Matsumura, Hiroki Aizawa, Takako Shiraki-Iida, Ryozo Nagai, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

53

Klotho Protein Protects against Endothelial Dysfunction

Yuichiro Saito, Takahiro Yamagishi, Tetsuya Nakamura, Yoshio Ohyama, Hiroki Aizawa, Tatsuo Suga, Yutaka Matsumura, Hiroaki Masuda, Masahiko Kurabayashi, Makoto Kuro-o, Yo-ichi Nabeshima, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

54

Molecular Cloning of RatklothocDNA: Markedly Decreased Expression ofklothoby Acute Inflammatory Stress

Yoshio Ohyama, Masahiko Kurabayashi, Hiroaki Masuda, Tetsuya Nakamura, Yasushi Aihara, Tadashi Kaname, Tatsuo Suga, Masashi Arai, Hiroki Aizawa, Yutaka Matsumura, Makoto Kuro-o, Yo-ichi Nabeshima, Ryo

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.35 MB

english, 1998

55

In Vivo klotho Gene Delivery Protects against Endothelial Dysfunction in Multiple Risk Factor Syndrome

Yuichiro Saito, Tetsuya Nakamura, Yoshio Ohyama, Toru Suzuki, Akihiro Iida, Takako Shiraki-Iida, Makoto Kuro-o, Yo-ichi Nabeshima, Masahiko Kurabayashi, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

56

Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during development and by angiotensin II

Ken-ichi Nakahara, Hiroshi Nishimura, Makoto Kuro-o, Shun-ichi Takewaki, Misaki Iwase, Akiyuki Ohkubo, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

57

Vascular smooth muscle differentiation during development is associated with a decrease in PDGF-A chain gene expression

Ryozo Nagai, Ken-ichi Nakahara, Makoto Kuro-o, Hiroshi Nishimura, Masanori Aikawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 104 KB

english, 1992

58

Klotho and aging

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2009

Language:

english

File:

PDF, 564 KB

english, 2009

59

The Klotho gene family as a regulator of endocrine fibroblast growth factors

Hiroshi Kurosu, Makoto Kuro-o

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

60

Endocrine FGFs and Klothos: emerging concepts

Journal:

Trends in Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 488 KB

english, 2008

61

Heterogeneity in smooth muscle cell population accumulating in the neointimas and the media of poststenotic dilatation of the rabbit carotid artery

Ei-ichi Okamoto, Kohji Imataka, Jun Fujii, Makoto Kuro-o, Ken-ichi Nakahara, Hiroshi Nishimura, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.92 MB

english, 1992

62

Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

Takako Shiraki-Iida, Hiroki Aizawa, Yutaka Matsumura, Susumu Sekine, Akihiro Iida, Hideharu Anazawa, Ryozo Nagai, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

Year:

1998

Language:

english

File:

PDF, 273 KB

english, 1998

63

Activation of Na+-H+ Antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system

Syin-ichi Takewaki, Makoto Kuro-o, Yukio Hiroi, Tsutomu Yamazaki, Tsuyoshi Noguchi, Akira Miyagishi, Ken-ichi Nakahara, Masanori Aikawa, Ichiro Manabe, Yoshio Yazaki, Ryozo Nagai

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1995

Language:

english

File:

PDF, 2.19 MB

english, 1995

64

Expression of Na+/Ca2+ exchanger (NCX1) gene in the developmental mouse embryo and adult mouse brain

Koji Wakimoto, Makoto Kuro-o, Noriyuki Yanaka, Issei Komuro, Yo-ichi Nabeshima, Yuji Imai

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 1.20 MB

english, 2001

65

Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes

Koji Wakimoto, Hisako Fujimura, Takahiro Iwamoto, Toru Oka, Kinji Kobayashi, Satomi Kita, Sumiyo Kudoh, Makoto Kuro-o, Yo-ichi Nabeshima, Munekazu Shigekawa, Yuji Imai, Issei Komuro

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.45 MB

english, 2003

66

Disease model: human aging

Journal:

Trends in Molecular Medicine

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

67

Association of klotho gene polymorphism with bone density and spondylosis of the lumbar spine in postmenopausal women

N Ogata, Y Matsumura, M Shiraki, K Kawano, Y Koshizuka, T Hosoi, K Nakamura, M Kuro-o, H Kawaguchi

Journal:

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

68

Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging

T. Utsugi, T. Ohno, Y. Ohyama, T. Uchiyama, Y. Saito, Y. Matsumura, H. Aizawa, H. Itoh, M. Kurabayashi, S. Kawazu, S. Tomono, Y. Oka, T. Suga, M. Kuro-o, Y. Nabeshima, R. Nagai

Journal:

Year:

2000

Language:

english

File:

PDF, 264 KB

english, 2000

69

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF23, Klotho and Vitamin D Interactions:

Year:

2012

Language:

english

File:

PDF, 255 KB

english, 2012

70

The emerging role of Klotho in clinical nephrology

Hu, M. C., Kuro-o, M., Moe, O. W.

Journal:

Nephrology Dialysis Transplantation

Year:

2012

Language:

english

File:

PDF, 259 KB

english, 2012

71

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF23 as a Novel Therapeutic Target

Year:

2012

Language:

english

File:

PDF, 158 KB

english, 2012

72

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || Regulation of Ion Channels by Secreted Klotho

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

73

12 Loss of Gastric Interstitial Cells of Cajal and Impaired Electrical Pacemaking in Klotho Mice, an Animal Model of Aging

Ferenc Izbeki, Andrea Lorincz, David T. Asuzu, Laura Popko, David L. Young, Michael R. Bardsley, Yujiro Hayashi, Makoto Kuro-o, Gianrico Farrugia, Tamas Ordog

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010

74

Antioxidant protection with probucol ameliorates endothelial function and klotho gene expression in Otsuka Long-Evans Tokushima Fatty (OLETF) rats

Y. Saito, T. Nakamura, M. Kurabayashi, M. Kuro-o, Y. Nabeshima, R. Nagai

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 286 KB

english, 2000

75

Existence of three distinct βtype myosin isozymes in human heart: A marked difference in their expression according to developmental stage

H. Tsuchimochi, M. Kuro-o, F. Takaku, Y. Yazaki

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1986

Language:

english

File:

PDF, 87 KB

english, 1986

76

Effects of pressure overload on the distribution of myosin isozymes in human ventricle—A difference in behavior of ordinary and specialized myocardium

Y. Yazaki, M. Kuro-o, H. Tsuchimochi, F. Takaku

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1986

Language:

english

File:

PDF, 89 KB

english, 1986

77

Phenotypic Modulation of Smooth Muscle Cells during Progression of Human Atherosclerosis as Determined by Altered Expression of Myosin Heavy Chain Isoforms

MASANORI AIKAWA, HYO-SOO KIM, MAKOTO KURO-O, ICHIRO MANABE, MASAFUMI WATANABE, HIROSHI YAMAGUCHI, YOSHIO YAZAKI, RYOZO NAGAI

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.00 MB

english, 1994

78

Adhesion of klotho-deficient eryptotic erythrocytes to endothelial cells

Abed, M., Towhid, S. T., Feger, M., Schmidt, S., Kuro-o, M., Gawaz, M., Lang, F.

Journal:

Acta Physiologica

Year:

2013

Language:

english

File:

PDF, 258 KB

english, 2013

79

Cytogenetic studies of Hynobiidae (Urodela)

Kuro-o, M., Ikebe, C., Izumisawa, Y., Fujinuki, Y., Sasaki, K., Saso, K., Akaba, K., Kohno, S.

Journal:

Cytogenetic and Genome Research

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

80

Renal and Extrarenal Actions of Klotho

Hu, Ming Chang, Kuro-o, Makoto, Moe, Orson W.

Journal:

Seminars in Nephrology

Year:

2013

Language:

english

File:

PDF, 1.25 MB

english, 2013

81

The Antiaging Protein Klotho Enhances Oligodendrocyte Maturation and Myelination of the CNS

Chen, C.-D., Sloane, J. A., Li, H., Aytan, N., Giannaris, E. L., Zeldich, E., Hinman, J. D., Dedeoglu, A., Rosene, D. L., Bansal, R., Luebke, J. I., Kuro-o, M., Abraham, C. R.

Journal:

Journal of Neuroscience

Year:

2013

Language:

english

File:

PDF, 1.88 MB

english, 2013

82

Fibroblast Growth Factor 23 and Klotho: Physiology and Pathophysiology of an Endocrine Network of Mineral Metabolism

Hu, Ming Chang, Shiizaki, Kazuhiro, Kuro-o, Makoto, Moe, Orson W.

Journal:

Annual Review of Physiology

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

83

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF23 in Chronic Kidney Disease

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

84

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

Hu, M. C., Shi, M., Zhang, J., Pastor, J., Nakatani, T., Lanske, B., Razzaque, M. S., Rosenblatt, K. P., Baum, M. G., Kuro-o, M., Moe, O. W.

Journal:

The FASEB Journal

Year:

2010

Language:

english

File:

PDF, 652 KB

english, 2010

85

Phosphate and Klotho

Journal:

Kidney International

Year:

2011

Language:

english

File:

PDF, 178 KB

english, 2011

86

Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

Hu, M. C., Shi, M., Zhang, J., Quinones, H., Griffith, C., Kuro-o, M., Moe, O. W.

Journal:

Journal of the American Society of Nephrology

Year:

2011

Language:

english

File:

PDF, 908 KB

english, 2011

87

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || The Structural Biology of the FGF19 Subfamily

Year:

2012

Language:

english

File:

PDF, 927 KB

english, 2012

88

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || Secreted Klotho and Chronic Kidney Disease

Year:

2012

Language:

english

File:

PDF, 506 KB

english, 2012

89

Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2013

Language:

english

File:

PDF, 1013 KB

english, 2013

90

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 ||

Year:

2012

Language:

english

File:

PDF, 3.82 MB

english, 2012

91

1,25(OH)2 vitamin D3-dependent inhibition of platelet Ca2+ signaling and thrombus formation in klotho-deficient mice

Borst, O., Munzer, P., Schmid, E., Schmidt, E.-M., Russo, A., Walker, B., Yang, W., Leibrock, C., Szteyn, K., Schmidt, S., Elvers, M., Faggio, C., Shumilina, E., Kuro-o, M., Gawaz, M., Lang, F.

Journal:

The FASEB Journal

Year:

2014

Language:

english

File:

PDF, 1.18 MB

english, 2014

92

Amadori products promote cellular senescence activating insulin-like growth factor-1 receptor and down-regulating the antioxidant enzyme catalase

del Nogal-Ávila, María, Troyano-Suárez, Nuria, Román-García, Pablo, Cannata-Andía, Jorge B., Rodriguez-Puyol, Manuel, Rodriguez-Puyol, Diego, Kuro-O, Makoto, Ruiz-Torres, María P.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 2.37 MB

english, 2013

93

The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice

Chen, Tso-Hsiao, Kuro-o, Makoto, Chen, Cheng-Hsien, Sue, Yuh-Mou, Chen, Yen-Cheng, Wu, Ho-Han, Cheng, Chung-Yi

Journal:

European Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 550 KB

english, 2013

94

FIBROBLAST GROWTH FACTOR 23 INDUCES LEFT VENTRICULAR HYPERTROPHY

Amaral, Ansel Philip, Oskouei, Behzad, Hu, Ming-Chang, Moe, Orson, Kuro-o, Makoto, Brand, Marcus, Hare, Joshua, Wolf, Myles, Faul, Christian

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 89 KB

english, 2012

95

Regulation of Oxidative Stress by the Anti-aging Hormone Klotho

Yamamoto, M., Clark, J. D., Pastor, J. V., Gurnani, P., Nandi, A., Kurosu, H., Miyoshi, M., Ogawa, Y., Castrillon, D. H., Rosenblatt, K. P., Kuro-o, M.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 844 KB

english, 2005

96

FGF-23-Klotho Signaling Stimulates Proliferation and Prevents Vitamin D-Induced Apoptosis

Damian Medici, Mohammed S. Razzaque, Stephelynn DeLuca, Trent L. Rector, Bo Hou, Kihwa Kang, Regina Goetz, Moosa Mohammadi, Makoto Kuro-o, Bjorn R. Olsen and Beate Lanske

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.99 MB

english, 2008

97

Klotho and Phosphate Are Modulators of Pathologic Uremic Cardiac Remodeling

Hu, M. C., Shi, M., Cho, H. J., Adams-Huet, B., Paek, J., Hill, K., Shelton, J., Amaral, A. P., Faul, C., Taniguchi, M., Wolf, M., Brand, M., Takahashi, M., Kuro-o, M., Hill, J. A., Moe, O. W.

Journal:

Journal of the American Society of Nephrology

Year:

2015

Language:

english

File:

PDF, 2.61 MB

english, 2015

98

Fibroblast growth factor 23 and uremic vascular calcification: is it time to escalate from biomarker status to pathogenic agent?

Moe, Orson W, Kuro-o, Makoto

Journal:

Kidney International

Year:

2014

Language:

english

File:

PDF, 83 KB

english, 2014

99

Genetic Deficiency of Anti-Aging Gene Klotho Exacerbates Early Nephropathy in STZ-Induced Diabetes in Male Mice

Lin, Yi, Kuro-o, Makoto, Sun, Zhongjie

Journal:

Year:

2013

Language:

english

File:

PDF, 650 KB

english, 2013

100

The demonstration of Klotho deficiency in human chronic kidney disease with a novel synthetic antibody

Barker, S. L., Pastor, J., Carranza, D., Quinones, H., Griffith, C., Goetz, R., Mohammadi, M., Ye, J., Zhang, J., Hu, M. C., Kuro-o, M., Moe, O. W., Sidhu, S. S.

Journal:

Nephrology Dialysis Transplantation

Year:

2015

Language:

english

File:

PDF, 847 KB

english, 2015