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51

Enduring involvement of tau, β-amyloid, α-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism–dementia complex of Guam (ALS/PDC)

Judith Miklossy, John C. Steele, Sheng Yu, Sherman McCall, Glenn Sandberg, Edith G. McGeer, Patrick L. McGeer

Journal:

Acta Neuropathologica

Year:

2008

Language:

english

File:

PDF, 697 KB

english, 2008

52

TDP-43 pathology in familial British dementia

Claudia Schwab, Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Sheng Yu, Patrick L. McGeer

Journal:

Acta Neuropathologica

Year:

2009

Language:

english

File:

PDF, 583 KB

english, 2009

53

Distinct glutaminyl cyclase expression in Edinger–Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Aβ pathology in Alzheimer’s disease

Markus Morawski, Maike Hartlage-Rübsamen, Carsten Jäger, Alexander Waniek, Stephan Schilling, Claudia Schwab, Patrick L. McGeer, Thomas Arendt, Hans-Ulrich Demuth, Steffen Roßner

Journal:

Acta Neuropathologica

Year:

2010

Language:

english

File:

PDF, 3.05 MB

english, 2010

54

Optineurin is colocalized with ubiquitin in Marinesco bodies

Claudia Schwab, Sheng Yu, Patrick L. McGeer

Journal:

Acta Neuropathologica

Year:

2012

Language:

english

File:

PDF, 284 KB

english, 2012

55

Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy

Tetsuaki Arai, Kenji Ikeda, Haruhiko Akiyama, Yasuo Shikamoto, Kuniaki Tsuchiya, Saburo Yagishita, Thomas Beach, Joseph Rogers, Claudia Schwab, Patrick L. McGeer

Journal:

Acta Neuropathologica

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

56

Distinct distribution of apolipoprotein E and β-amyloid immunoreactivity in the hippocampus of Parkinson dementia complex of Guam

Claudia Schwab, John C. Steele, Haruhiko Akiyama, Patrick L. McGeer

Journal:

Acta Neuropathologica

Year:

1996

Language:

english

File:

PDF, 465 KB

english, 1996

57

Expression of interleukin-1 receptor antagonist protein in post-mortem human brain tissues of Alzheimer’s disease and control cases

Osamu Yasuhara, Akinor Matsuo, Kazuhiro Terai, Douglas G. Walker, Ann E. Berger, Ichiro Akiguchi, Jun Kimura, Patrick L. McGeer

Journal:

Acta Neuropathologica

Year:

1997

Language:

english

File:

PDF, 727 KB

english, 1997

58

Effects of Obovatol on GSH Depleted Glia-Mediated Neurotoxicity and Oxidative Damage

Lee, Moonhee, Kwon, Byoung-Mok, Suk, Kyoungho, McGeer, Edith, McGeer, Patrick L.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2012

Language:

english

File:

PDF, 608 KB

english, 2012

59

Erratum to: Effects of Obovatol on GSH Depleted Glia-Mediated Neurotoxicity and Oxidative Damage

Lee, Moonhee, Kwon, Byoung-Mog, Suk, Kyoungho, McGeer, Edith, McGeer, Patrick L.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2012

Language:

english

File:

PDF, 51 KB

english, 2012

60

Separation of large DNA restriction fragments on a size-exclusion column by a nonideal mechanism

Barry E. Boyes, Douglas G. Walker, Patrick L. McGeer

Journal:

Analytical Biochemistry

Year:

1988

Language:

english

File:

PDF, 1.06 MB

english, 1988

61

Effect of fixatives on rat brain acetylcholinesterase activity

Edith G. McGeer, Patrick L. McGeer

Journal:

Journal of Neuroscience Methods

Year:

1989

Language:

english

File:

PDF, 218 KB

english, 1989

62

Enhancement of Progenitor Cell Division in the Dentate Gyrus Triggered by Initial Limbic Seizures in Rat Models of Epilepsy

Eiji Nakagawa, Yoshinari Aimi, Osamu Yasuhara, Ikuo Tooyama, Morimi Shimada, Patrick L. McGeer, Hiroshi Kimura

Journal:

Year:

2000

Language:

english

File:

PDF, 2.74 MB

english, 2000

63

Specificity of mechanisms for plaque removal after Aβ immunotherapy for Alzheimer disease

Akiyama, Haruhiko, McGeer, Patrick L

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 484 KB

english, 2004

64

Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor

Andis Klegeris, Christopher J Bissonnette, Patrick L McGeer

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 372 KB

english, 2003

65

Inflammation and the Degenerative Diseases of Aging

PATRICK L. McGEER, EDITH G. McGEER

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 732 KB

english, 2004

66

Variable Deposition of Amyloid β-Protein (Aβ) with the Carboxy-Terminus that Ends at Residue Valine40(Aβ40) in the Cerebral Cortex of Patients with Alzheimer's Disease: A Double-Labeling Immunohistochemical Study with Antibodies Specific for Aβ40 and the Aβ that Ends at Residues Alanine42/Threonine43(Aβ42)

Haruhiko Akiyama, Hiroshi Mori, Naruhiko Sahara, Hiromi Kondo, Kenji Ikeda, Toru Nishimura, Tatsuro Oda, Patrick L. McGeer

Journal:

Neurochemical Research

Year:

1997

Language:

english

File:

PDF, 1.20 MB

english, 1997

67

Acidic fibroblast growth factor-like immunoreactivity in rat brain following cerebral infarction

Yasushi Hara, Ikuo Tooyama, Osamu Yasuhara, Haruhiko Akiyama, Patrick L. McGeer, Jyoji Handa, Hiroshi Kimura

Journal:

Year:

1994

Language:

english

File:

PDF, 1.54 MB

english, 1994

68

Subcellular localization of the low density lipoprotein receptor-related protein (α2-macroglobulin receptor) in human brain

Ikuo Tooyama, Toshio Kawamata, Haruhiko Akiyama, Hiroshi Kimura, Soren K. Moestrup, Jorgen Gliemann, Akinori Matsuo, Patrick L. McGeer

Journal:

Year:

1995

Language:

english

File:

PDF, 619 KB

english, 1995

69

Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins

Claudia Schwab, John C. Steele, Patrick L. McGeer

Journal:

Year:

1996

Language:

english

File:

PDF, 3.01 MB

english, 1996

70

Reactive microglia specifically associated with amyloid plaques in Alzheimer's disease brain tissue express melanotransferrin

Wilfred A. Jefferies, Michael R. Food, Reinhard Gabathuler, Sylvia Rothenberger, Tatsuo Yamada, Osamu Yasuhara, Patrick L. McGeer

Journal:

Year:

1996

Language:

english

File:

PDF, 551 KB

english, 1996

71

Enhancement of immunoreactivity for NF-κB in the hippocampal formation and cerebral cortex of Alzheimer's disease

Kazuhiro Terai, Akinori Matsuo, Patrick L. McGeer

Journal:

Year:

1996

Language:

english

File:

PDF, 3.82 MB

english, 1996

72

Coincident expression and distribution of melanotransferrin and transferrin receptor in human brain capillary endothelium

Sylvia Rothenberger, Michael R. Food, Reinhard Gabathuler, Malcolm L. Kennard, Tatsuo Yamada, Osamu Yasuhara, Patrick L. McGeer, Wilfred A. Jefferies

Journal:

Year:

1996

Language:

english

File:

PDF, 814 KB

english, 1996

73

Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels

Moonhee Lee, Nattinee Jantaratnotai, Edith McGeer, James G. McLarnon, Patrick L. McGeer

Journal:

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

74

Neurotoxic factors released by stimulated human monocytes and THP-1 cells

Moonhee Lee, Kyoungho Suk, Yunhee Kang, Edith McGeer, Patrick L. McGeer

Journal:

Year:

2011

Language:

english

File:

PDF, 675 KB

english, 2011

75

Mechanisms of Mg2+ inhibition of BzATP-dependent Ca2+ responses in THP-1 monocytes

Nattinee Jantaratnotai, Patrick L. McGeer, James G. McLarnon

Journal:

Year:

2012

Language:

english

File:

PDF, 613 KB

english, 2012

76

S- but not R-enantiomers of flurbiprofen and ibuprofen reduce human microglial and THP-1 cell neurotoxicity

Andis Klegeris, John Maguire, Patrick L McGeer

Journal:

Journal of Neuroimmunology

Year:

2004

Language:

english

File:

PDF, 233 KB

english, 2004

77

Differential expression of interferon-γ receptor on human glial cells in vivo and in vitro

Sadayuki Hashioka, Andis Klegeris, Claudia Schwab, Sheng Yu, Patrick L. McGeer

Journal:

Journal of Neuroimmunology

Year:

2010

Language:

english

File:

PDF, 2.41 MB

english, 2010

78

STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes

Sadayuki Hashioka, Andis Klegeris, Hong Qing, Patrick L. McGeer

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

79

SARS corona virus peptides recognized by antibodies in the sera of convalescent cases

Jian-Ping Guo, Martin Petric, William Campbell, Patrick L McGeer

Journal:

Year:

2004

Language:

english

File:

PDF, 415 KB

english, 2004

80

Inhibitory action of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide (PK 11195) on some mononuclear phagocyte functions

Andis Klegeris, Edith G McGeer, Patrick L McGeer

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 264 KB

english, 2000

81

Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain

Koji Yasojima, Jeff Kuret, Anthony J DeMaggio, Edith McGeer, Patrick L McGeer

Journal:

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

82

Expression of complement messenger RNAs by human endothelial cells

Andis Klegeris, Christopher J Bissonnette, Katerina Dorovini-Zis, Patrick L McGeer

Journal:

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

83

Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer’s disease

Koji Yasojima, Claudia Schwab, Edith G. McGeer, Patrick L. McGeer

Journal:

Year:

2000

Language:

english

File:

PDF, 1.02 MB

english, 2000

84

Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid β-protein (Aβ) deposition

Haruhiko Akiyama, Hiromi Kondo, Kenji Ikeda, Masanori Kato, Patrick L McGeer

Journal:

Year:

2001

Language:

english

File:

PDF, 1.51 MB

english, 2001

85

Axonal damage and demyelination in the white matter after chronic cerebral hypoperfusion in the rat

Hideaki Wakita, Hidekazu Tomimoto, Ichiro Akiguchi, Akinori Matsuo, Jin-Xi Lin, Masafumi Ihara, Patrick-L McGeer

Journal:

Year:

2002

Language:

english

File:

PDF, 1008 KB

english, 2002

86

Enhancement of immunoreactivity for NF-κB in human cerebral infarctions

Kazuhiro Terai, Akinori Matsuo, Edith G McGeer, Patrick L McGeer

Journal:

Year:

1996

Language:

english

File:

PDF, 1.65 MB

english, 1996

87

Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α

Andis Klegeris, Douglas G Walker, Patrick L McGeer

Journal:

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

88

Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains

Kenji Takami, Kazuhiro Terai, Akinori Matsuo, Douglas G Walker, Patrick L McGeer

Journal:

Year:

1997

Language:

english

File:

PDF, 1.98 MB

english, 1997

89

Apolipoprotein E4 (ApoE4) but not ApoE3 or ApoE2 potentiates β-amyloid protein activation of complement in vitro

Patrick L. McGeer, Douglas G. Walker, Robert E. Pitas, Robert W. Mahley, Edith G. McGeer

Journal:

Year:

1997

Language:

english

File:

PDF, 653 KB

english, 1997

90

Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain

Yong Shen, Rena Li, Edith G McGeer, Patrick L McGeer

Journal:

Year:

1997

Language:

english

File:

PDF, 487 KB

english, 1997

91

Expression of the proto-oncogene Ret, a component of the GDNF receptor complex, persists in human substantia nigra neurons in Parkinson's disease

Douglas G. Walker, Thomas G. Beach, Ren Xu, Jack Lile, Klaus D. Beck, Edith G. McGeer, Patrick L. McGeer

Journal:

Year:

1998

Language:

english

File:

PDF, 998 KB

english, 1998

92

Immunohistochemical analyses of fibroblast growth factor receptor-1 in the human substantia nigra. Comparison between normal and Parkinson's disease cases

Douglas G Walker, Kazuhiro Terai, Akinori Matsuo, Thomas G Beach, Edith G McGeer, Patrick L McGeer

Journal:

Year:

1998

Language:

english

File:

PDF, 357 KB

english, 1998

93

Fibroblast growth factor receptor-1 expression in the cortex and hippocampus in Alzheimer's disease

Kenji Takami, Akinori Matsuo, Kazuhiro Terai, Douglas G. Walker, Edith G. McGeer, Patrick L. McGeer

Journal:

Year:

1998

Language:

english

File:

PDF, 2.88 MB

english, 1998

94

Expression of complement C4 and C9 genes by human astrocytes

Douglas G Walker, Seung U Kim, Patrick L McGeer

Journal:

Year:

1998

Language:

english

File:

PDF, 364 KB

english, 1998

95

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs

Koji Yasojima, Claudia Schwab, Edith G. McGeer, Patrick L. McGeer

Journal:

Year:

1999

Language:

english

File:

PDF, 1.45 MB

english, 1999

96

Complement regulators C1 inhibitor and CD59 do not significantly inhibit complement activation in Alzheimer disease

Koji Yasojima, Edith G. McGeer, Patrick L. McGeer

Journal:

Year:

1999

Language:

english

File:

PDF, 214 KB

english, 1999

97

Anti-inflammatory effects of cerebrocrast in a model of rat paw edema and on mononuclear THP-1 cells

Andis Klegeris, Evaldas Liutkevicius, Gene Mikalauskiene, Gunars Duburs, Patrick L McGeer, Vija Klusa

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 177 KB

english, 2002

98

Expression of COX-1 and COX-2 mRNAs in atherosclerotic plaques

Patrick L. McGeer, Edith G. McGeer, Koji Yasojima

Journal:

Experimental Gerontology

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

99

The importance of inflammatory mechanisms in alzheimer disease

Edith G. McGeer, Patrick L. McGeer

Journal:

Experimental Gerontology

Year:

1998

Language:

english

File:

PDF, 261 KB

english, 1998

100

R-(−)-Deprenyl Inhibits Monocytic THP-1 Cell Neurotoxicity Independently of Monoamine Oxidase Inhibition

Andis Klegeris, Patrick L. McGeer

Journal:

Experimental Neurology

Year:

2000

Language:

english

File:

PDF, 113 KB

english, 2000

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