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1

Characterizing biological products and assessing comparability following manufacturing changes

Chirino, Arthur J, Mire-Sluis, Anthony

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

2

Scientific and regulatory considerations on the immunogenicity of biologics

Gopi Shankar, Elizabeth Shores, Carrie Wagner, Anthony Mire-Sluis

Journal:

Trends in Biotechnology

Year:

2006

Language:

english

File:

PDF, 130 KB

english, 2006

3

The Effects of Environmental Influences and Post-translational Modification on the Biological Activity of Granulocyte Colony-stimulating Factor

ANTHONY R. MIRE-SLUIS, HELEN A. ABERNETHY, CARL DOLMAN, ROBIN THORPE

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 111 KB

english, 1999

4

The development of a World Health Organisation international standard for islet cell antibodies: the aims and design of an international collaborative study

Anthony R. Mire-Sluis, Rose Gaines Das, Åke Lernmark

Journal:

Diabetes/Metabolism Research and Reviews

Year:

1999

Language:

english

File:

PDF, 69 KB

english, 1999

5

Platelet c-mpl expression is dysregulated in patients with essential thrombocythaemia but this is not of diagnostic value

Claire N. Harrison, Rosemary E. Gale, Francesco Pezella, Anthony Mire-Sluis, Samuel J. Machin, David C. Linch

Journal:

British Journal of Haematology

Year:

1999

Language:

english

File:

PDF, 405 KB

english, 1999

6

Bioanalytical Method Validation for Macromolecules in Support of Pharmacokinetic Studies

JoMarie Smolec, Binodh DeSilva, Wendell Smith, Russell Weiner, Marian Kelly, Ben Lee, Masood Khan, Richard Tacey, Howard Hill, Abbie Celniker, Vinod Shah, Ronald Bowsher, Anthony Mire-Sluis, John W. A

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

7

Advances in the assessment and control of the effector functions of therapeutic antibodies

Jiang, Xu-Rong, Song, An, Bergelson, Svetlana, Arroll, Thomas, Parekh, Bhavin, May, Kimberly, Chung, Shan, Strouse, Robert, Mire-Sluis, Anthony, Schenerman, Mark

Journal:

Nature Reviews Drug Discovery

Year:

2011

Language:

english

File:

PDF, 419 KB

english, 2011

8

Progress in the Use of Biological Assays During the Development of Biotechnology Products

Anthony R. Mire-Sluis

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 204 KB

english, 2001

9

Development of a Lyophilization Formulation that Preserves the Biological Activity of the Platelet-inducing Cytokine Interleukin-11 at Low Concentrations

CHRISTOPHER PAGE, PETER DAWSON, DAVID WOOLLACOTT, ROBIN THORPE, ANTHONY MIRE-SLUIS

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

10

The Biological Properties, Assay, and Standardization of Interferon-Alpha: A Need for a WHO Collaborative Study

MIRE-SLUIS, ANTHONY R., DAS, ROSE GAINES, ZOON, KATHRYN, PADILLA, ANA, THORPE, ROBIN, MEAGER, ANTHONY

Journal:

Journal of Interferon & Cytokine Research

Year:

1996

Language:

english

File:

PDF, 237 KB

english, 1996

11

Cytokines—Protein Structure and Biological Activity: A Complex Relationship with Implications for Biological Assays and Standardization

Anthony R. Mire-Sluis

Journal:

Year:

1993

File:

PDF, 813 KB

1993

12

Biological Assays: Their Role in the Development and Quality Control of Recombinant Biological Medicinal Products

Anthony R. Mire-Sluis, Terry Gerrard, Rose Gaines Das, Ana Padilla, Robin Thorpe

Journal:

Year:

1996

Language:

english

File:

PDF, 284 KB

english, 1996

13

Recombinant Human Albumin as a Stabilizer for Biological Materials and for the Preparation of International Reference Reagents

Edward Tarelli, Anthony Mire-Sluis, Helen A. Tivnann, Barbara Bolgiano, Dennis T. Crane, Christopher Gee, Xavier Lemercinier, Margareth L. Athayde, Nicholas Sutcliffe, Patrick H. Corran, Brian Raffert

Journal:

Year:

1998

Language:

english

File:

PDF, 229 KB

english, 1998

14

Biological Standardization and Control at the World Health Organization: Successes, Current Issues and Future Challenges

Dorothea Sesardic, Anthony Mire-Sluis

Journal:

Year:

2000

Language:

english

File:

PDF, 84 KB

english, 2000

15

Immunoassays for detecting cytokines: What are they really measuring?

Anthony R. Mire-Sluis, Rose Gaines-Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1995

Language:

english

File:

PDF, 353 KB

english, 1995

16

Quantitative cell line based bioassays for human cytokines

Anthony R. Mire-Sluis, Lisa Page, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1995

Language:

english

File:

PDF, 875 KB

english, 1995

17

An antiproliferative bioassay for interleukin-4

Lisa A. Page, Max S. Topp, Robin Thorpe, Anthony R. Mire-Sluis

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 438 KB

english, 1996

18

Assays for measuring soluble cellular adhesion molecules and soluble cytokine receptors

Anthony Meager, Christopher Bird, Anthony Mire-Sluis

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 1.67 MB

english, 1996

19

Implications for the assay and biological properties of interleukin-3 Results of a WHO international collaborative study

Anthony R. Mire-Sluis, Rose Gaines Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 1013 KB

english, 1996

20

Implications for the assay and biological activity of interleukin-4 Results of a WHO international collaborative study

Anthony R. Mire-Sluis, Rose Gaines Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

21

An anti-cytokine bioactivity assay for interferons-α, -β and -ω

Anthony R. Mire-Sluis, Lisa A. Page, Anthony Meager, Janice Igaki, Jamie Lee, Sheila Lyons, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 667 KB

english, 1996

22

Cytokines and disease

Anthony Mire-Sluis

Journal:

Trends in Biotechnology

Year:

1993

Language:

english

File:

PDF, 477 KB

english, 1993

23

A novel, sensitive bioassay for transforming growth factor β

Lisa A. Randall, Meenu Wadhwa, Robin Thorpe, Anthony R. Mire-Sluis

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1994

Language:

english

File:

PDF, 43 KB

english, 1994

24

Meeting report on protein particles and immunogenicity of therapeutic proteins: Filling in the gaps in risk evaluation and mitigation

John Carpenter, Barry Cherney, Anthony Lubinecki, Stacey Ma, Ewa Marszal, Anthony Mire-Sluis, Thomas Nikolai, Jeanne Novak, Jack Ragheb, Jan Simak

Journal:

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

25

Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products

Anthony R Mire-Sluis, Yu Chen Barrett, Viswanath Devanarayan, Eugen Koren, Hank Liu, Mauricio Maia, Thomas Parish, George Scott, Gopi Shankar, Elizabeth Shores, Steven J Swanson, Gary Taniguchi, Danie

Journal:

Journal of Immunological Methods

Year:

2004

Language:

english

File:

PDF, 373 KB

english, 2004

26

Recommendations for the design, optimization, and qualification of cell-based assays used for the detection of neutralizing antibody responses elicited to biological therapeutics

Shalini Gupta, Stephen R. Indelicato, Vijay Jethwa, Thomas Kawabata, Marian Kelley, Anthony R. Mire-Sluis, Susan M. Richards, Bonita Rup, Elizabeth Shores, Steven J. Swanson, Eric Wakshull

Journal:

Journal of Immunological Methods

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

27

Establishment of new and replacement World Health Organization International Biological Standards for human interferon alpha and omega

Anthony Meager, Rose Gaines Das, Kathryn Zoon, Anthony Mire-Sluis

Journal:

Journal of Immunological Methods

Year:

2001

Language:

english

File:

PDF, 125 KB

english, 2001

28

Implications for the assay and biological activity of interleukin-8: results of a WHO international collaborative study

Anthony R. Mire-Sluis, Rose Gaines Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1997

Language:

english

File:

PDF, 1.36 MB

english, 1997

29

WHO cytokine standardization: facilitating the development of cytokines in research, diagnosis and as therapeutic agents

Anthony R. Mire-Sluis, Rose Gaines Das, Ana Padilla

Journal:

Journal of Immunological Methods

Year:

1998

Language:

english

File:

PDF, 393 KB

english, 1998

30

Development of a continuous IL-7-dependent murine pre-B cell line PB-1 suitable for the biological characterisation and assay of human IL-7

Anthony R Mire-Sluis, Lyn Healey, Steve Griffiths, David Hockley, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

2000

Language:

english

File:

PDF, 401 KB

english, 2000

31

Cytokines: from technology to therapeutics

Anthony R Mire-Sluis

Journal:

Trends in Biotechnology

Year:

1999

Language:

english

File:

PDF, 182 KB

english, 1999

32

The effects of interleukin-8 on neutrophil fMetLeuPhe receptors, CD11b expression and metabolic activity, in comparison and combination with other cytokines

Pamela J. Roberts, Arnold R. Pizzey, Asim Khwaja, Julia E. Carver, Anthony R. Mire-Sluis, David C. Linch

Journal:

British Journal of Haematology

Year:

1993

Language:

english

File:

PDF, 856 KB

english, 1993

33

A sensitive human cell line based bioassay for megakaryocyte growth and development factor or thrombopoietin

Lisa A. Page, Robin Thorpe, Anthony R. Mire-Sluis

Journal:

Year:

1996

Language:

english

File:

PDF, 64 KB

english, 1996

34

Interleukin-2 binding to activated human T lymphocytes triggers generation of cyclic AMP but not of inositol phosphates

R.Gitendra Wickremasinghe, Anthony R. Mire-Sluis, A.Victor Hoffbrand

Journal:

Year:

1987

Language:

english

File:

PDF, 420 KB

english, 1987

35

The binding of ligands to the 55 kDa component of the interleukin-2 receptor triggers increased turnover of phosphate bound to an 85 kDa protein: Evidence for the role of cyclic AMP

Anthony R. Mire-Sluis, A.Victor Hoffbrand, R.Gitendra Wickremasinghe

Journal:

Year:

1989

Language:

english

File:

PDF, 327 KB

english, 1989

36

Inhibitors of arachidonic acid lipoxygenase impair the stimulation of inositol phospholipid hydrolysis by the T lymphocyte mitogen phytohaemagglutinin

Anthony R. Mire-Sluis, Cheryl A. Cox, A.Victor Hoffbrand, R.Gitendra Wickremasinghe

Journal:

Year:

1989

Language:

english

File:

PDF, 522 KB

english, 1989

37

Transforming growth factor-β1 blocks interleukin 4 induced cell proliferation by inhibiting a protein tyrosine phosphatase essential for signal transduction

Anthony R. Mire-Sluis, Lisa Page, Meenu Wadhwa, Robin Thorpe

Journal:

Year:

1994

Language:

english

File:

PDF, 1.89 MB

english, 1994

38

Evidence that guanine-nucleotide binding regulatory proteins couple cell-surface receptors to the breakdown of inositol-containing lipids during T-lymphocyte mitogenesis

Anthony R. Mire-Sluis, A. Victor Hoffbrand, R. Gitendra Wickremasinghe

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 688 KB

english, 1987

39

The international standard for granulocyte colony stimulating factor (G-CSF) Evaluation in an international collaborative study

Anthony R. Mire-Sluis, Rose Gaines Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1995

Language:

english

File:

PDF, 855 KB

english, 1995

40

A novel, sensitive bioassay for transforming growth factor β

Lisa A. Randall, Meenu Wadhwa, Robin Thorpe, Anthony R. Mire-Sluis

Journal:

Journal of Immunological Methods

Year:

1993

Language:

english

File:

PDF, 503 KB

english, 1993

41

The international standard for granulocyte-macrophage colony stimulating factor (GM-CSF) Evaluation in an international collaborative study

Anthony R. Mire-Sluis, Rose Gaines Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1995

Language:

english

File:

PDF, 745 KB

english, 1995

42

The international standard for macrophage colony stimulating factor (M-CSF) Evaluation in an international collaborative study

Anthony R Mire-Sluis, Rose Gaines Das, Robin Thorpe

Journal:

Journal of Immunological Methods

Year:

1995

Language:

english

File:

PDF, 1.00 MB

english, 1995

43

Peptide growth factors and their receptors I and II (Handbook of experimental pharmacology vol. 95): edited by M. B. Sporn and A. B. Roberts, Springer-Verlag, 1990. DM 498.00 (Pt I), DM 498.00 (Pt II), (xxviii + 794 pages, Pt I; xxviii + 727 pages, Pt II) ISBN 3 540 51184 9 (Pt I); 3 540 51185 7 (Pt II)

Jane Robinson, Anthony Mire-Sluis

Journal:

Trends in Pharmacological Sciences

Year:

1991

Language:

english

File:

PDF, 292 KB

english, 1991

44

Constructing an immunogenicity risk assessment for follow-on biologics

Chamberlain, Paul, Mire-Sluis, Anthony

Journal:

Journal of Generic Medicines The Business Journal for the Generic Medicines Sector

Year:

2005

Language:

english

File:

PDF, 130 KB

english, 2005

45

Quality Considerations for Recombinant DNA-Derived Biological Therapeutic Products

Mire-Sluis, Anthony, Thorpe, Robin

Journal:

Year:

1999

Language:

english

File:

PDF, 249 KB

english, 1999

46

Encyclopedia of Life Sciences || Interleukins

Mire-Sluis, Anthony R

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

47

Blood Polymorphonuclear Leukocytes From the Majority of Sickle Cell Patients in the Crisis Phase of the Disease Show Enhanced Adhesion to Vascular Endothelium and Increased Expression of CD64

Fadlon, Emma, Vordermeier, Susanne, Pearson, Thomas C., Mire-Sluis, Anthony R., Dumonde, Dudley C., Phillips, Julia, Fishlock, Keith, Alun Brown, K.

Journal:

Year:

1998

File:

PDF, 231 KB

1998

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