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1

Design, synthesis and biological evaluation of imidazopyridine/pyrimidine-chalcone derivatives as potential anticancer agents

Kamal, Ahmed, Reddy, J. Surendranadha, Ramaiah, M. Janaki, Dastagiri, D., Bharathi, E. Vijaya, Prem Sagar, M. Victor, Pushpavalli, S. N. C. V. L., Ray, Paramita, Pal-Bhadra, Manika

Journal:

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

2

Synthesis of Imidazothiazole–Chalcone Derivatives as Anticancer and Apoptosis Inducing Agents

Dr. Ahmed Kamal, D. Dastagiri, Dr. M. Janaki Ramaiah, J. Surendranadha Reddy, E. Vijaya Bharathi, Chatla Srinivas, S. N. C. V. L. Pushpavalli, Dhananjaya Pal, Dr. Manika Pal-Bhadra

Journal:

Year:

2010

Language:

english

File:

PDF, 410 KB

english, 2010

3

Synthesis and anti-cancer activity of chalcone linked imidazolones

Ahmed Kamal, G. Ramakrishna, P. Raju, A. Viswanath, M. Janaki Ramaiah, G. Balakishan, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 584 KB

english, 2010

4

Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents

Ahmed Kamal, J. Surendranadha Reddy, M. Janaki Ramaiah, D. Dastagiri, E. Vijaya Bharathi, M. Ameruddin Azhar, Farheen Sultana, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Su

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 738 KB

english, 2010

5

Synthesis and biological evaluation of novel Mannich bases of 2-arylimidazo[2,1-b]benzothiazoles as potential anti-cancer agents

Ravindra M. Kumbhare, K. Vijay Kumar, M. Janaki Ramaiah, Tulshiram Dadmal, S.N.C.V.L. Pushpavalli, Debasmita Mukhopadhyay, B. Divya, T. Anjana Devi, Umesh Kosurkar, Manika Pal-Bhadra

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 978 KB

english, 2011

6

Green chemistry approach for the synthesis and stabilization of biocompatible gold nanoparticles and their potential applications in cancer therapy

Mukherjee, Sudip, Sushma, V, Patra, Sujata, Barui, Ayan Kumar, Bhadra, Manika Pal, Sreedhar, Bojja, Patra, Chitta Ranjan

Journal:

Year:

2012

Language:

english

File:

PDF, 1.88 MB

english, 2012

7

3-Diarylethyne quinazolinones: a new class of senescence inducers

Kamal, Ahmed, Sultana, Farheen, Ramaiah, M. Janaki, Srikanth, Y. V. V., Viswanath, A., Bharathi, E. Vijaya, Nayak, Ranjita, Pushpavalli, S. N. C. V. L., Srinivas, Chatla, Pal-Bhadra, Manika

Journal:

Year:

2013

Language:

english

File:

PDF, 726 KB

english, 2013

8

Potential Theranostics Application of Bio-Synthesized Silver Nanoparticles (4-in-1 System)

Mukherjee, Sudip, Chowdhury, Debabrata, Kotcherlakota, Rajesh, Patra, Sujata, B, Vinothkumar, Bhadra, Manika Pal, Sreedhar, Bojja, Patra, Chitta Ranjan

Journal:

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

9

Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species

Mathew, Rebecca, Pal Bhadra, Manika, Bhadra, Utpal

Journal:

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

10

Design, synthesis, in silico pharmacokinetics prediction and biological evaluation of 1,4-dihydroindeno[1,2-c]pyrazole chalcone as EGFR /Akt pathway inhibitors

Khan, Irfan, Garikapati, Koteswara Rao, Setti, Aravind, Shaik, Anver Basha, Kanth Makani, Venkatesh Krishna, Shareef, Mohd Adil, Rajpurohit, Hemshikha, Vangara, Namratha, Pal-Bhadra, Manika, Kamal, Ah

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.05 MB

english, 2018

11

Histone deacetylase (Rpd3) regulates Drosophila early brain development via regulation of Tailless

Das, Paromita, Bhadra, Manika Pal

Journal:

Year:

2020

File:

PDF, 3.22 MB

2020

12

Correction to âHistone deacetylase (Rpd3) regulates Drosophila early brain development via regulation of Taillessâ

Das, Paromita, Bhadra, Manika Pal

Journal:

Year:

2020

File:

PDF, 195 KB

2020

13

ChemInform Abstract: Synthesis and Potential Cytotoxic Activity of New Phenanthrylphenol-Pyrrolobenzodiazepines.

Ahmed Kamal, Kokkonda Sreekanth, P. Praveen Kumar, Nagula Shankaraiah, G. Balakishan, M. Janaki Ramaiah, S. N. C. V. L. Pushpavalli, Paramita Ray, Manika Pal Bhadra

Journal:

Year:

2010

File:

PDF, 23 KB

2010

14

ChemInform Abstract: Synthesis and Biological Evaluation of Novel Mannich Bases of 2-Arylimidazo[2,1-b]benzothiazoles as Potential Anticancer Agents.

Ravindra M. Kumbhare, K. Vijay Kumar, M. Janaki Ramaiah, Tulshiram Dadmal, S. N. C. V. L. Pushpavalli, Debasmita Mukhopadhyay, B. Divya, T. Anjana Devi, Umesh Kosurkar, Manika Pal-Bhadra

Journal:

Year:

2012

Language:

english

File:

PDF, 37 KB

english, 2012

15

ChemInform Abstract: Synthesis and Anticancer Activity of Chalcone-Pyrrolobenzodiazepine Conjugates Linked via 1,2,3-Triazole Ring Side-Armed with Alkane Spacers.

Ahmed Kamal, S. Prabhakar, M. Janaki Ramaiah, P. Venkat Reddy, Ch. Ratna Reddy, A. Mallareddy, Nagula Shankaraiah, T. Lakshmi Narayan Reddy, S. N. C. V. L. Pushpavalli, Manika Pal-Bhadra

Journal:

Year:

2012

File:

PDF, 28 KB

2012

16

Development of Pyrrolo[2,1-c][1,4]benzodiazepine β-Galactoside Prodrugs for Selective Therapy of Cancer by ADEPT and PMT

Ahmed Kamal, Venkatesh Tekumalla, Anita Krishnan, Manika Pal-Bhadra, Utpal Bhadra

Journal:

Year:

2008

Language:

english

File:

PDF, 894 KB

english, 2008

17

Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates

Ahmed Kamal, E. Vijaya Bharathi, M. Janaki Ramaiah, J. Surendranadha Reddy, D. Dastagiri, A. Viswanath, Farheen Sultana, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Surekha

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 435 KB

english, 2010

18

Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents

Ahmed Kamal, E. Vijaya Bharathi, M. Janaki Ramaiah, D. Dastagiri, J. Surendranadha Reddy, A. Viswanath, Farheen Sultana, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Hemant Kumar Srivastava, G. Narahari

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 805 KB

english, 2010

19

Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole–pyrrolo[2,1-c][1,4]benzodiazepine conjugates

Ahmed Kamal, K. Srinivasa Reddy, M. Naseer A. Khan, Rajesh V.C.R.N.C. Shetti, M. Janaki Ramaiah, S.N.C.V.L. Pushpavalli, Chatla Srinivas, Manika Pal-Bhadra, Mukesh Chourasia, G. Narahari Sastry, Aarti

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.33 MB

english, 2010

20

Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole–pyrrolobenzodiazepine conjugates

Ahmed Kamal, D. Dastagiri, M. Janaki Ramaiah, E. Vijaya Bharathi, J. Surendranadha Reddy, G. Balakishan, Pranjal Sarma, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Surekha Z

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 693 KB

english, 2010

21

Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents

Ahmed Kamal, M. Kashi Reddy, M. Janaki Ramaiah, Rajender, J. Surendranadha Reddy, Y.V.V. Srikanth, D. Dastagiri, E. Vijaya Bharathi, S.N.C.V.L. Pushpavalli, Pranjal Sarma, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

22

Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents

Ahmed Kamal, Paidakula Suresh, M. Janaki Ramaiah, Adla Mallareddy, Banala Ashwini Kumar, Paidakula Raju, J. Vinay Gopal, S.N.C.V.L. Pushpavalli, A. Lavanya, Pranjal Sarma, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

23

Synthesis and biological evaluation of anilino substituted pyrimidine linked pyrrolobenzodiazepines as potential anticancer agents

Ahmed Kamal, J. Surendranadha Reddy, M. Janaki Ramaiah, E. Vijaya Bharathi, D. Dastagiri, M. Kashi Reddy, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 407 KB

english, 2010

24

Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres

M Janaki Ramaiah, SNCVL Pushpavalli, G Rama Krishna, Pranjal Sarma, Debasmita Mukhopadhyay, Ahmed Kamal, Utpal Bhadra, Manika Pal Bhadra

Journal:

Cancer Cell International

Year:

2011

Language:

english

File:

PDF, 7.81 MB

english, 2011

25

Effect of Benzothiazole based conjugates in causing apoptosis by Regulating p53, PTEN and MAP Kinase proteins affecting miR-195a and miR-101-1

SNCVL Pushpavalli, M Janaki Ramaiah, Ch Srinivas, Debasmita Mukhopadhya, JL Aditya, Ravindra M Kumbhare, Utpal Bhadra, Manika Pal Bhadra

Journal:

Cancer Cell International

Year:

2011

Language:

english

File:

PDF, 839 KB

english, 2011

26

Sub-cellular internalization and organ specific oral elivery of PABA nanoparticles by side chain variation

Jhillu S Yadav, Pragna P Das, T Lakshminarayan Reddy, Indira Bag, Priyadarshini M Lavanya, Bulusu Jagannadh, Debendra K Mohapatra, Manika Pal Bhadra, Utpal Bhadra

Journal:

Journal of Nanobiotechnology

Year:

2011

Language:

english

File:

PDF, 3.16 MB

english, 2011

27

Synthesis and potential cytotoxic activity of new phenanthrylphenol-pyrrolobenzodiazepines

Ahmed Kamal, Kokkonda Sreekanth, P. Praveen Kumar, Nagula Shankaraiah, G. Balakishan, M. Janaki Ramaiah, S.N.C.V.L. Pushpavalli, Paramita Ray, Manika Pal Bhadra

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 826 KB

english, 2010

28

MicroRNAs – micro in size but macro in function

Sunit K. Singh, Manika Pal Bhadra, Hermann J. Girschick, Utpal Bhadra

Journal:

Year:

2008

Language:

english

File:

PDF, 378 KB

english, 2008

29

10.1038/5926

Birchler, James A, Pal-Bhadra, Manika, Bhadra, Utpal

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 131 KB

english, 1999

30

Dosage Dependent Gene Regulation and the Compensation of the X Chromosome inDrosophilaMales

James A. Birchler, Manika Pal-Bhadra, Utpal Bhadra

Journal:

Year:

2003

Language:

english

File:

PDF, 407 KB

english, 2003

31

Anthranilamide–Pyrazolo[1,5-a]pyrimidine Conjugates as p53 Activators in Cervical Cancer Cells

Dr. Ahmed Kamal, Jaki R. Tamboli, Dr. M. Janaki Ramaiah, Dr. S. F. Adil, G. Koteswara Rao, A. Viswanath, Adla Mallareddy, Dr. S. N. C. V. L. Pushpavalli, Dr. Manika Pal-Bhadra

Journal:

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

32

New Linearly and Angularly Fused Quinazolinones: Synthesis through Gold(I)-Catalyzed Cascade Reactions and Anticancer Activities

Nitin T. Patil, Pediredla G. V. V. Lakshmi, Balasubramanian Sridhar, Sujata Patra, Manika Pal Bhadra, Chitta Ranjan Patra

Journal:

European Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 970 KB

english, 2012

33

Drosophila Argonaute-1is critical for transcriptional cosuppression and heterochromatin formation

Sreerangam N. C. V. L. Pushpavalli, Indira Bag, Manika Pal-Bhadra, Utpal Bhadra

Journal:

Chromosome Research

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

34

Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4′-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents

Ahmed Kamal, Paidakula Suresh, M. Janaki Ramaiah, Adla Mallareddy, Syed Imthiajali, S.N.C.V.L. Pushpavalli, A. Lavanya, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

35

Synthesis, anticancer activity and apoptosis inducing ability of bisindole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates

Ahmed Kamal, Y.V.V. Srikanth, M. Janaki Ramaiah, M. Naseer Ahmed Khan, M. Kashi Reddy, Md. Ashraf, A. Lavanya, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

36

Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers

Ahmed Kamal, S. Prabhakar, M. Janaki Ramaiah, P. Venkat Reddy, Ch. Ratna Reddy, A. Mallareddy, Nagula Shankaraiah, T. Lakshmi Narayan Reddy, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 824 KB

english, 2011

37

Synthesis and apoptosis inducing ability of new anilino substituted pyrimidine sulfonamides as potential anticancer agents

Ahmed Kamal, D. Dastagiri, M. Janaki Ramaiah, J. Surendranadha Reddy, E. Vijaya Bharathi, M. Kashi Reddy, M. Victor Prem Sagar, T. Lakshminarayan Reddy, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 724 KB

english, 2011

38

Dosage-Dependent Gene Regulation in Multicellular Eukaryotes: Implications for Dosage Compensation, Aneuploid Syndromes, and Quantitative Traits

James A. Birchler, Utpal Bhadra, Manika Pal Bhadra, Donald L. Auger

Journal:

Developmental Biology

Year:

2001

Language:

english

File:

PDF, 386 KB

english, 2001

39

Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents

Ravindra M. Kumbhare, Umesh B. Kosurkar, M. Janaki Ramaiah, Tulshiram L. Dadmal, S.N.C.V.L. Pushpavalli, Manika Pal-Bhadra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 383 KB

english, 2012

40

RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements

Charlotte Grimaud, Frédéric Bantignies, Manika Pal-Bhadra, Pallavi Ghana, Utpal Bhadra, Giacomo Cavalli

Journal:

Year:

2006

Language:

english

File:

PDF, 919 KB

english, 2006

41

Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes

Manika Pal-Bhadra, Utpal Bhadra, Daniel E. Jackson, Linga Mamatha, Pil-Hoon Park, Shivendra D. Shukla

Journal:

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

42

Cosuppression of Nonhomologous Transgenes in Drosophila Involves Mutually Related Endogenous Sequences

Manika Pal-Bhadra, Utpal Bhadra, James A. Birchler

Journal:

Year:

1999

Language:

english

File:

PDF, 553 KB

english, 1999

43

Cosuppression in Drosophila: Gene Silencing of Alcohol dehydrogenase by white-Adh Transgenes Is Polycomb Dependent

Manika Pal-Bhadra, Utpal Bhadra, James A Birchler

Journal:

Year:

1997

Language:

english

File:

PDF, 3.12 MB

english, 1997

44

Making noise about silence: repression of repeated genes in animals

James A Birchler, Manika Pal Bhadra, Utpal Bhadra

Journal:

Current Opinion in Genetics & Development

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

45

RNAi Related Mechanisms Affect Both Transcriptional and Posttranscriptional Transgene Silencing in Drosophila

Manika Pal-Bhadra, Utpal Bhadra, James A Birchler

Journal:

Year:

2002

Language:

english

File:

PDF, 559 KB

english, 2002

46

Total Synthesis of Azumamide E and Sugar Amino Acid-Containing Analogue

Chandrasekhar, Srivari, Rao, Chennamaneni Lohitha, Seenaiah, Mallikanti, Naresh, Police, Jagadeesh, Bharatam, Manjeera, Dharani, Sarkar, Arpita, Bhadra, Manika Pal

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

47

Plant HDAC inhibitor chrysin arrest cell growth and inducep21WAF1by altering chromatin of STAT response element in A375 cells

Manika Pal-Bhadra, M Janaki Ramaiah, T Lakshminarayan Reddy, Anita Krishnan, SNCVL Pushpavalli, K Suresh Babu, Ashok K Tiwari, J Madhusudana Rao, Jhillu S Yadav, Utpal Bhadra

Journal:

Year:

2012

Language:

english

File:

PDF, 1.85 MB

english, 2012

48

Design, synthesis and biological evaluation of imidazo[1,5-a]pyridine–PBD conjugates as potential DNA-directed alkylating agents

Kamal, Ahmed, Ramakrishna, G., Ramaiah, M. Janaki, Viswanath, A., Rao, A. V. Subba, Bagul, Chandrakant, Mukhopadyay, Debasmitha, Pushpavalli, S. N. C. V. L., Pal-Bhadra, Manika

Journal:

Year:

2013

Language:

english

File:

PDF, 586 KB

english, 2013

49

Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells

Mohapatra, Debendra K., Reddy, D. Sai, Janaki Ramaiah, M., Ghosh, Sowjanya, Pothula, Vikram, Lunavath, Swetha, Thomas, Shine, Pushpa Valli, S.N.C.V.L., Bhadra, Manika Pal, Yadav, Jhillu S.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 3.23 MB

english, 2014

50

Imidazo–benzothiazoles a potent microRNA modulator involved in cell proliferation

Pushpavalli, Sreerangam N.C.V.L., Janaki Ramaiah, M., Lavanya, A., Raksha Ganesh, A., Kumbhare, Ravindra M., Bhadra, Kaustav, Bhadra, Utpal, Pal-Bhadra, Manika

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 984 KB

english, 2012