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51

HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein

Maurizio Cianfriglia, Maria Luisa Dupuis, Agnese Molinari, Antonio Verdoliva, Roberta Costi, Clementina Maria Galluzzo, Mauro Andreotti, Andrea Cara, Roberto Di Santo, Lucia Palmisano

Journal:

Year:

2007

Language:

english

File:

PDF, 1.29 MB

english, 2007

52

Urging inclusion for interculturalism: fostering excellence in a Cypriot primary school

Hajisoteriou, Christina, Angelides, Panayiotis, Costi, Andri, Hadjiaggeli, Maria

Journal:

Intercultural Education

Year:

2011

Language:

english

File:

PDF, 108 KB

english, 2011

53

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

Realini, Natalia, Solorzano, Carlos, Pagliuca, Chiara, Pizzirani, Daniela, Armirotti, Andrea, Luciani, Rosaria, Costi, Maria Paola, Bandiera, Tiziano, Piomelli, Daniele

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 640 KB

english, 2013

54

Simple but Highly Effective Three-Dimensional Chemical-Feature-Based Pharmacophore Model for Diketo Acid Derivatives as Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors

Di Santo, Roberto, Fermeglia, Maurizio, Ferrone, Marco, Paneni, Maria Silvia, Costi, Roberta, Artico, Marino, Roux, Alessandra, Gabriele, Mirko, Tardif, Keith D., Siddiqui, Aleem, Pricl, Sabrina

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 816 KB

english, 2005

55

What Is Acupuncture After All?

Costi, Jéssica Maria

Journal:

Archives of Internal Medicine

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

56

2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes

Piras, Sandra, Carta, Antonio, Briguglio, Irene, Corona, Paola, Paglietti, Giuseppe, Luciani, Rosaria, Costi, Maria Paola, Ferrari, Stefania

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.99 MB

english, 2014

57

Development and validation of a multiplex PCR assay for identification of the epidemic ST-258/512 KPC-producing Klebsiella pneumoniae clone

Adler, Amos, Khabra, Efrat, Chmelnitsky, Inna, Giakkoupi, Panagiota, Vatopoulos, Alkiviadis, Mathers, Amy J., Yeh, Anthony J., Sifri, Costi D., De Angelis, Giulia, Tacconelli, Evelina, Villegas, Maria

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

58

Corrigendum to “Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the thymidylate synthase reaction” [J. Mol. Struct. (Theochem) 343 (1995) 1–9]

Rastelli, Giulio, Costi, Maria Paola

Journal:

Computational and Theoretical Chemistry

Year:

2015

Language:

english

File:

PDF, 169 KB

english, 2015

59

Targeting Class A and C Serine β-Lactamases with a Broad-Spectrum Boronic Acid Derivative

Tondi, Donatella, Venturelli, Alberto, Bonnet, Richard, Pozzi, Cecilia, Shoichet, Brian K., Costi, Maria Paola

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 12.81 MB

english, 2014

60

Geometrically and Conformationally Restrained Cinnamoyl Compounds as Inhibitors of HIV-1 Integrase: Synthesis, Biological Evaluation, and Molecular Modeling

Artico, Marino, Di Santo, Roberto, Costi, Roberta, Novellino, Ettore, Greco, Giovanni, Massa, Silvio, Tramontano, Enzo, Marongiu, Maria E., De Montis, Antonella, La Colla, Paolo

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 254 KB

english, 1998

61

Effectiveness of Standing Frame on Constipation in Children with Cerebral Palsy: A Single-Subject Study

Rivi, Elena, Filippi, Mariacristina, Fornasari, Elisa, Mascia, Maria Teresa, Ferrari, Adriano, Costi, Stefania

Journal:

Occupational Therapy International

Year:

2014

Language:

english

File:

PDF, 799 KB

english, 2014

62

Book reviews

Hadjimichalis, Costis, Cooke, Phil, Vaiou, Dina, Loukaki, Arpyro, Kaika, Maria, Barabas, P., Corren, Nurit, Alterman, Rachelle

Journal:

European Planning Studies

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

63

Familial Mediterranean Fever Associated with MEFV Mutations in a Large Cohort of Cypriot Patients

Neocleous, Vassos, Costi, Constantina, Kyriakou, Christina, Kyriakides, Tassos C, Shammas, Christos, Skordis, Nicos, Toumba, Meropi, Kyriakou, Sophia, Koliou, Maria, Kousparou, Marianna, Onoufriou, Ma

Journal:

Annals of Human Genetics

Year:

2015

Language:

english

File:

PDF, 138 KB

english, 2015

64

Alanine Mutants of the Interface Residues of Human Thymidylate Synthase Decode Key Features of the Binding Mode of Allosteric Anticancer Peptides

Tochowicz, Anna, Santucci, Matteo, Saxena, Puneet, Guaitoli, Giambattista, Trande, Matteo, Finer-Moore, Janet, Stroud, Robert M., Costi, Maria P.

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 4.44 MB

english, 2015

65

New oral anticoagulants and pituitary apoplexy

Doglietto, Francesco, Costi, Emanuele, Villaret, Andrea Bolzoni, Mardighian, Dikran, Fontanella, Marco Maria, Giustina, Andrea

Journal:

Year:

2016

Language:

english

File:

PDF, 284 KB

english, 2016

66

Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase

Salo-Ahen, Outi M. H., Tochowicz, Anna, Pozzi, Cecilia, Cardinale, Daniela, Ferrari, Stefania, Boum, Yap, Mangani, Stefano, Stroud, Robert M., Saxena, Puneet, Myllykallio, Hannu, Costi, Maria Paola, P

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

67

The Hippo Pathway and YAP/TAZ–TEAD Protein–Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment

Santucci, Matteo, Vignudelli, Tatiana, Ferrari, Stefania, Mor, Marco, Scalvini, Laura, Bolognesi, Maria Laura, Uliassi, Elisa, Costi, Maria Paola

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 8.72 MB

english, 2015

68

Apparent Homozygosity of p.Phe508del in CFTR due to a Large Gene Deletion of Exons 4–11

Neocleous, Vassos, Yiallouros, Panayiotis K., Tanteles, George A., Costi, Constantina, Moutafi, Maria, Ioannou, Phivos, Patsalis, Philippos C., Sismani, Carolina, Phylactou, Leonidas A.

Journal:

Case Reports in Genetics

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

69

Acute functional reactivation of the language network during awake intraoperative brain mapping

Spena, Giannantonio, Costi, Emanuele, Panciani, Pier Paolo, Roca, Elena, Migliorati, Karol, Fontanella, Marco Maria

Journal:

Year:

2015

Language:

english

File:

PDF, 304 KB

english, 2015

70

A support vector machine tool for adaptive tomotherapy treatments: Prediction of head and neck patients criticalities

Guidi, Gabriele, Maffei, Nicola, Vecchi, Claudio, Ciarmatori, Alberto, Mistretta, Grazia Maria, Gottardi, Giovanni, Meduri, Bruno, Baldazzi, Giuseppe, Bertoni, Filippo, Costi, Tiziana

Journal:

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

71

Enhanced anti-hyperproliferative activity of human thymidylate synthase inhibitor peptide by Solid Lipid Nanoparticle delivery

Sacchetti, Francesca, Marraccini, Chiara, D'Arca, Domenico, Pelà, Michela, Pinetti, Diego, Maretti, Eleonora, Hanuskovà, Miriam, Iannuccelli, Valentina, Costi, Maria Paola, Leo, Eliana

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2015

Language:

english

File:

PDF, 824 KB

english, 2015

72

Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance

Taddia, Laura, D’Arca, Domenico, Ferrari, Stefania, Marraccini, Chiara, Severi, Leda, Ponterini, Glauco, Assaraf, Yahuda G., Marverti, Gaetano, Costi, Maria Paola

Journal:

Drug Resistance Updates

Year:

2015

Language:

english

File:

PDF, 8.10 MB

english, 2015

73

Educational and digital inclusion for subjects with autism spectrum disorders in 1:1 technological configuration

Santarosa, Lucila Maria Costi, Conforto, Débora

Journal:

Computers in Human Behavior

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

74

[IEEE 2015 International Symposium on Computers in Education (SIIE) - Setubal, Portugal (2015.11.25-2015.11.27)] 2015 International Symposium on Computers in Education (SIIE) - Accessibility guidelines for a distance education platform

Santarosa, Lucila Maria Costi, Conforto, Debora

Year:

2015

Language:

english

File:

PDF, 618 KB

english, 2015

75

Anastomotic recurrence of colon cancer: Genetic analysis challenges the widely held theories of cancerous cells’ intraluminal implantation and metachronous carcinogenesis

Costi, Renato, Santi, Caterina, Bottarelli, Lorena, Azzoni, Cinzia, Zarzavadjian Le Bian, Alban, Ricco’, Matteo, Sarli, Leopoldo, Silini, Enrico Maria, Violi, Vincenzo

Journal:

Journal of Surgical Oncology

Year:

2016

Language:

english

File:

PDF, 103 KB

english, 2016

76

Association between cytokine gene polymorphisms and outcome of hepatitis B virus infection in southern Brazil

Gusatti, Carolina de Souza, Costi, Cintia, de Medeiros, Rúbia Marília, Halon, Maria Laura, Grandi, Tarciana, Medeiros, Arlete Ferrari Rech, da Silva, Cláudia Maria Dornelles, Rodenbusch, Rodrigo, Silv

Journal:

Journal of Medical Virology

Year:

2016

Language:

english

File:

PDF, 86 KB

english, 2016

77

An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases

Quotadamo, Antonio, Linciano, Pasquale, Davoli, Paolo, Tondi, Donatella, Costi, Maria, Venturelli, Alberto

Journal:

Year:

2016

Language:

english

File:

PDF, 440 KB

english, 2016

78

Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case

Siragusa, Lydia, Luciani, Rosaria, Borsari, Chiara, Ferrari, Stefania, Costi, Maria Paola, Cruciani, Gabriele, Spyrakis, Francesca

Journal:

Year:

2016

Language:

english

File:

PDF, 1.97 MB

english, 2016

79

Virtual screening and X-ray crystallography Identify non-substrate analog inhibitors of Flavin-dependent Thymidylate Synthase

Luciani, Rosaria, Saxena, Puneet, Surade, Sachin, Santucci, Matteo, Venturelli, Alberto, Borsari, Chiara, Marverti, Gaetano, Ponterini, Glauco, Ferrari, Stefania, Blundell, Tom L., Costi, Maria Paola

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 800 KB

english, 2016

80

Target-based approaches for the discovery of new antimycobacterial drugs

Borsari, Chiara, Ferrari, Stefania, A.Venturelli,, Costi, Maria Paola

Journal:

Drug Discovery Today

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

81

Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones?

Sacchetti, Francesca, D'Arca, Domenico, Genovese, Filippo, Pacifico, Salvatore, Maretti, Eleonora, Hanuskova, Miriam, Iannuccelli, Valentina, Costi, Maria Paola, Leo, Eliana

Journal:

Drug Development and Industrial Pharmacy

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

82

Tumour necrosis factor -308 and -238 promoter polymorphisms are predictors of a null virological response in the treatment of Brazilian hepatitis C patients

Grandi, Tarciana, Silva, Cláudia Maria Dornelles da, Amaral, Karine Medeiros, Picon, Paulo Dornelles, Costi, Cintia, Fré, Nicole Nascimento da, Fiegenbaum, Marilu, Gregianini, Tatiana Schäffer, Niel,

Journal:

Memórias do Instituto Oswaldo Cruz

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

83

Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule

Bruno, Stefano, Uliassi, Elisa, Zaffagnini, Mirko, Prati, Federica, Bergamini, Christian, Amorati, Riccardo, Paredi, Gianluca, Margiotta, Marilena, Conti, Paola, Costi, Maria Paola, Kaiser, Marcel, Ca

Journal:

Chemical Biology & Drug Design

Year:

2017

Language:

english

File:

PDF, 612 KB

english, 2017

84

Design, synthesis and biological evaluation of non-covalent AmpC β-lactamases inhibitors

Genovese, Filippo, Lazzari, Sandra, Venturi, Ettore, Costantino, Luca, Blazquez, Jesus, Ibacache-Quiroga, Claudia, Costi, Maria Paola, Tondi, Donatella

Journal:

Medicinal Chemistry Research

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

85

Expert system classifier for adaptive radiation therapy in prostate cancer

Guidi, Gabriele, Maffei, Nicola, Vecchi, Claudio, Gottardi, Giovanni, Ciarmatori, Alberto, Mistretta, Grazia Maria, Mazzeo, Ercole, Giacobazzi, Patrizia, Lohr, Frank, Costi, Tiziana

Journal:

Australasian Physical & Engineering Sciences in Medicine

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

86

CDKN2AandMC1Rvariants found in Cypriot patients diagnosed with cutaneous melanoma

KOULERMOU, GEORGIA, SHAMMAS, CHRISTOS, VASSILIOU, ANDREAS, KYRIAKIDES, TASSOS C., COSTI, CONSTANTINA, NEOCLEOUS, VASSOS, PHYLACTOU, LEONIDAS A., PANTELIDOU, MARIA

Journal:

Journal of Genetics

Year:

2017

Language:

english

File:

PDF, 157 KB

english, 2017

87

Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus

Tonelli, Michele, Naesens, Lieve, Gazzarrini, Sabrina, Santucci, Matteo, Cichero, Elena, Tasso, Bruno, Moroni, Anna, Costi, Maria Paola, Loddo, Roberta

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

88

The Future of Drug Development for Neglected Tropical Diseases: How the European Commission Can Continue to Make a Difference

Pierce, Raymond J., MacDougall, Jane, Leurs, Rob, Costi, Maria Paola

Journal:

Trends in Parasitology

Year:

2017

Language:

english

File:

PDF, 523 KB

english, 2017

89

TRAP1: A viable therapeutic target for future cancer treatments?

Lettini, Giacomo, Maddalena, Francesca, Sisinni, Lorenza, Condelli, Valentina, Matassa Swann, Danilo, Costi, Maria Paola, Simoni, Daniele, Esposito, Franca, Landriscina, Matteo

Journal:

Expert Opinion on Therapeutic Targets

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

90

SPIE Proceedings [SPIE European Conferences on Biomedical Optics - Munich, Germany (Sunday 25 June 2017)] Novel Biophotonics Techniques and Applications IV - On the feasibility of a CENTA-based biosensor to measure antibiotics concentration in milk

Amelink, Arjen, Vitkin, I. Alex, Ferrari, Luca, Rovati, Luigi, Costi, Maria Paola, Venturelli, Alberto, Luciani, Rosaria, Cattini, Stefano

Year:

2017

File:

PDF, 563 KB

2017

91

Return to work in European Cancer survivors: a systematic review

Paltrinieri, Sara, Fugazzaro, Stefania, Bertozzi, Lucia, Bassi, Maria Chiara, Pellegrini, Martina, Vicentini, Massimo, Mazzini, Elisa, Costi, Stefania

Journal:

Supportive Care in Cancer

Year:

2018

Language:

english

File:

PDF, 585 KB

english, 2018

92

Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)

Francesconi, Valeria, Giovannini, Luca, Santucci, Matteo, Cichero, Elena, Costi, Maria Paola, Naesens, Lieve, Giordanetto, Fabrizio, Tonelli, Michele

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.88 MB

english, 2018

93

Pharmacokinetics and disposition of miltefosine in healthy mice and hamsters experimentally infected with Leishmania infantum

Jiménez-Antón, M. Dolores, García-Calvo, Estefanía, Gutiérrez, Cristina, Escribano, Mª.D., Kayali, Nour, Luque-García, José L., Olías-Molero, Ana Isabel, Corral, María J., Costi, Maria P., Torrado, Ju

Journal:

European Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 271 KB

english, 2018

94

Permeation through the Cell Membrane of a Boron-Based β-Lactamase Inhibitor

Minozzi, Manuela, Lattanzi, Gianluca, Benz, Roland, Costi, Maria P., Venturelli, Alberto, Carloni, Paolo, van Veen, Hendrik W.

Journal:

Year:

2011

Language:

english

File:

PDF, 661 KB

english, 2011

95

Hepatitis B Virus Genotype D Isolates Circulating in Chapecó, Southern Brazil, Originate from Italy

Gusatti, Carolina Souza, Costi, Cintia, Halon, Maria Laura, Grandi, Tarciana, Medeiros, Arlete Ferrari Rech, Silva, Cláudia Maria Dornelles, Gomes, Selma Andrade, Silva, Marcia Susana Nunes, Niel, Chr

Journal:

Year:

2015

Language:

english

File:

PDF, 439 KB

english, 2015

96

Feasibility Study on a Measurement Method and a Portable Measuring System to Estimate the Concentration of Cloxacillin and β -Lactamase in Milk

Ferrari, Luca, Rovati, Luigi, Costi, Maria Paola, Luciani, Rosaria, Venturelli, Alberto, Cattini, Stefano

Journal:

Journal of Sensors

Year:

2017

Language:

english

File:

PDF, 2.03 MB

english, 2017

97

In This Issue, Volume 9, Issue 5

Costi, Maria Paola

Journal:

ACS Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

98

In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I

Herrmann, Fabian, Sivakumar, Nirina, Jose, Joachim, Costi, Maria, Pozzi, Cecilia, Schmidt, Thomas

Journal:

Year:

2017

Language:

english

File:

PDF, 12.95 MB

english, 2017

99

Design, Synthesis and Structure—Activity Relationships of a Phenotypic Small Library against Protozoan Infections

Uliassi, Elisa, Piazzi, Lorna, Belluti, Federica, Kaiser, Marcel, Brun, Reto, Gul, Sheraz, Ellinger, Bernhard, Moraes, Carolina B., Freitas-Junior, Lucio H., Borsari, Chiara, Costi, Maria Paola, Bolog

Journal:

Proceedings (American Bar Association. Section of International and Comparative Law)

Year:

2017

Language:

english

File:

PDF, 162 KB

english, 2017

100

Prevalence of hepatitis C virus and human immunodeficiency virus in a group of patients newly diagnosed with active tuberculosis in Porto Alegre, Southern Brazil

Costi, Cintia, Grandi, Tarciana, Halon, Maria Laura, Silva, Márcia Susana Nunes, Silva, Cláudia Maria Dornelles da, Gregianini, Tatiana Schäffer, Possuelo, Lia Gonçalves, Jarczewski, Carla Adriane, Ni

Journal:

Memórias do Instituto Oswaldo Cruz

Year:

2017

Language:

english

File:

PDF, 305 KB

english, 2017

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