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51

Sa.7. Distinct Roles for Pd-L1 and Pd-L2 in Regulating Host Immunity in EAE

Loise Francisco, Keturah Brown, Mary Keir, Arlene Sharpe

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 44 KB

english, 2006

52

OR.70. Effect of Rituximab (RTX) Treatment on the Immune System in Patients with Systemic Lupus Erythematosus (SLE) in the EXPLORER Trial

Gaik Tew, Nusrat Rabbee, John Monroe, Tim Behrens, Paul Brunetta, Mary Keir

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 40 KB

english, 2009

53

Anti-CD3 mAb treatment cures PDL1−/−.NOD mice of diabetes but precipitates fatal myocarditis

Bechara Mfarrej, Mary Keir, Shirine Dada, Subbulaxmi Trikudanathan, Mohamed H. Sayegh, Arlene H. Sharpe, Indira Guleria

Journal:

Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

54

Profile of Public Health Nutrition Personnel: Challenges for Population/System-Focused Roles and State-Level Monitoring

BETSY HAUGHTON, MARY STORY, BARBARA KEIR

Journal:

Journal of the American Dietetic Association

Year:

1998

File:

PDF, 734 KB

1998

55

Erratum: Malcolm A. Smith, John M. Maris, Richard Gorlick, E. Anders Kolb, Richard Lock, Hernan Carol, Stephen T. Keir, C. Patrick Reynolds, Min H. Kang, Christopher L. Morton, Jianrong Wu, Peter G. Smith, Jie Yu and Peter J. Houghton. Initial testing of the investigational NEDD8-activating enzyme inhibitor MLN4924 by the pediatric preclinical testing program. Pediatr Blood Cancer. 2012 August; 59(2):246-253

Malcolm A. Smith, John M. Maris, Richard Gorlick, E. Anders Kolb, Richard Lock, Hernan Carol, Stephen T. Keir, C. Patrick Reynolds, Min H. Kang, Christopher L. Morton, Jianrong Wu, Peter G. Smith, Jie

Journal:

Pediatric Blood & Cancer

Year:

2012

File:

PDF, 146 KB

2012

56

Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses

Manish J. Butte, Mary E. Keir, Theresa B. Phamduy, Arlene H. Sharpe, Gordon J. Freeman

Journal:

Year:

2007

Language:

english

File:

PDF, 1.15 MB

english, 2007

57

Bridging Toll-like- and B Cell-Receptor Signaling: Meet Me at the Autophagosome

John G. Monroe, Mary E. Keir

Journal:

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

58

Canada's national aquatic biological specimen bank and database

Daryl J. McGoldrick, Mandi G. Clark, Michael J. Keir, Sean M. Backus, Mary M. Malecki

Journal:

Journal of Great Lakes Research

Year:

2010

Language:

english

File:

PDF, 766 KB

english, 2010

59

Initial testing (stage 1) of the phosphatidylinositol 3′ kinase inhibitor, SAR245408 (XL147) by the pediatric preclinical testing program

C. Patrick Reynolds, Min H. Kang, Hernan Carol, Richard Lock, Richard Gorlick, E. Anders Kolb, Raushan T. Kurmasheva, Stephen T. Keir, John M. Maris, Catherine A. Billups, Peter J. Houghton, Malcolm A

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 389 KB

english, 2012

60

102 POSTER Pediatric Preclinical Testing Program (PPTP) evaluation of the VEGFR-2 Inhibitor AZD2171

M.A. Smith, J.M. Maris, S.T. Keir, R.B. Lock, R. Gorlick, E.A. Kolb, N. Keshelava, C.P. Reynolds, C. Morton, P.J. Houghton

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 72 KB

english, 2006

61

313 POSTER Pediatric preclinical testing program (PPTP) evaluation of the KSP inhibitor Ispinesib (SB-715992)

P.J. Houghton, J.M. Maris, H.S. Friedman, S.T. Keir, R.B. Lock, R. Gorlick, E.A. Kolb, C.P. Reynolds, C. Morton, M.A. Smith

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

62

322 POSTER Pediatric Preclinical Testing Program (PPTP) evaluation of the Src-Abl inhibitor dasatinib (BMS-354825)

M.A. Smith, J.M. Maris, S.T. Keir, H.S. Friedman, R.B. Lock, E.A. Kolb, N. Keshelava, C.P. Reynolds, C. Morton, P.J. Houghton

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

63

Cerebrospinal fluid nitrite/nitrate correlated with oxyhemoglobin and outcome in patients with subarachnoid hemorrhage

Konrad Rejdak, Axel Petzold, Martyn A. Sharpe, Andrew D. Kay, Mary Kerr, Geoff Keir, Edward J. Thompson, Gavin Giovannoni

Journal:

Journal of the Neurological Sciences

Year:

2004

Language:

english

File:

PDF, 208 KB

english, 2004

64

A Phase I Study of rHuMab Beta7 in Moderate to Severe Ulcerative Colitis (UC)

Paul J. Rutgeerts, Richard N. Fedorak, Daniel W. Hommes, Andreas Sturm, Daniel C. Baumgart, Brian Bressler, Stefan Schreiber, John C. Mansfield, Marna Williams, Mary E. Keir, Banmeet S. Anand, Diana L

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 49 KB

english, 2011

65

190 POSTER Pediatric Preclinical Testing Program (PPTP) evaluation of rapamycin combined with cytotoxic drugs used frequently in treatment of childhood cancer

P.J. Houghton, C.L. Morton, J.M. Maris, S.T. Keir, R.B. Lock, H. Carol, R. Gorlick, E.A. Kolb, M.H. Kang, M.A. Smith

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 64 KB

english, 2008

66

135 Pediatric Preclinical Testing Program (PPTP) stage 1 evaluation of JNJ-26481585, a second generation histone deacetylase inhibitor

M.A. Smith, J.M. Maris, S.T. Keir, R.B. Lock, H. Carol, E.A. Kolb, M.H. Kang, C.P. Reynolds, I. Hickson, P.J. Houghton

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

67

Initial testing (stage 1) of eribulin, a novel tubulin binding agent, by the pediatric preclinical testing program

Kolb, E. Anders, Gorlick, Richard, Reynolds, C. Patrick, Kang, Min H., Carol, Hernan, Lock, Richard, Keir, Stephen T., Maris, John M., Billups, Catherine A., DesJardins, Christopher, Kurmasheva, Raush

Journal:

Pediatric Blood & Cancer

Year:

2013

Language:

english

File:

PDF, 374 KB

english, 2013

68

Heterogeneous catalysts for the controlled ring-opening polymerisation of rac-lactide and homogeneous silsesquioxane model complexes

Jones, Matthew D., Davidson, Matthew G., Keir, Callum G., Wooles, Ashley J., Mahon, Mary F., Apperley, David C.

Journal:

Dalton Transactions

Year:

2008

Language:

english

File:

PDF, 140 KB

english, 2008

69

The integrated landscape of driver genomic alterations in glioblastoma

Frattini, Veronique, Trifonov, Vladimir, Chan, Joseph Minhow, Castano, Angelica, Lia, Marie, Abate, Francesco, Keir, Stephen T, Ji, Alan X, Zoppoli, Pietro, Niola, Francesco, Danussi, Carla, Dolgalev,

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 5.39 MB

english, 2013

70

Initial testing (stage 1) of temozolomide by the pediatric preclinical testing program

Keir, Stephen T., Maris, John M., Reynolds, C. Patrick, Kang, Min H., Kolb, E. Anders, Gorlick, Richard, Lock, Richard, Carol, Hernan, Morton, Christopher L., Wu, Jianrong, Kurmasheva, Raushan T., Hou

Journal:

Pediatric Blood & Cancer

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

71

Initial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program

Carol, Hernan, Maris, John M., Kang, Min H., Reynolds, C. Patrick, Kolb, E. Anders, Gorlick, Richard, Keir, Stephen T., Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Loc

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

72

Initial testing (stage 1) of the polo-like kinase inhibitor volasertib (BI 6727), by the Pediatric Preclinical Testing Program

Gorlick, Richard, Kolb, E. Anders, Keir, Stephen T., Maris, John M., Reynolds, C. Patrick, Kang, Min H., Carol, Hernan, Lock, Richard, Billups, Catherine A., Kurmasheva, Raushan T., Houghton, Peter J.

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 923 KB

english, 2014

73

133 Ron Receptor Tyrosine Kinase Agonist Antibodies Promote Epithelial Wound Healing in Mice and Are Potential Therapeutics for Inflammatory Bowel Disease

Kauder, Steven, Santell, Lydia, Zavala-Solorio, Jose, Mai, Elaine, Zhang, Juan, Wright, Lilyan, Hazen, Meredith, Liang, Wei-Ching, Wu, Yan, Hongo, Jo-Anne, Keir, Mary E., Lee, Wyne P., Young, Judy C.,

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 201 KB

english, 2013

74

Su1276 αE Integrin Expression As a Predictive Biomarker for Induction of Clinical Remission by Etrolizumab: Analysis of a Phase II Trial in Moderate-to-Severely Active Ulcerative Colitis

Keir, Mary E., Tew, Gaik Wei, Luca, Diana, Eastham-Anderson, Jeffrey, Diehl, Lauri, Egen, Jackson G., Vermeire, Severine, Mansfield, John C., Lamb, Christopher A., Feagan, Brian G., Panes, Julian, Bau

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 242 KB

english, 2014

75

Sequence Specific pausing of RecQ Helicase

Sun, Yuze, In, Junghoon, Seol, Yeonee, Sarkar, Susanta, Strub, Marie-Paule, Sarlós, Kata, Kovács, Mihály, Neuman, Keir

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 34 KB

english, 2013

76

159 Differentiation Between Etrolizumab (Rhumab Beta7) and Placebo in the Eucalyptus Phase II Randomized Double-Blind Placebo-Controlled Induction Study to Evaluate Efficacy and Safety in Patients With Refractory Moderate-to-Severely Active Ulcerative Colitis

Vermeire, Severine, O'Byrne, Sharon, Williams, Marna, Mansfield, John C., Feagan, Brian G., Panes, Julian, Baumgart, Daniel C., Schreiber, Stefan, Dotan, Iris, Sandborn, William, Keir, Mary E., Luca,

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

77

Sa1241 Pharmacology of Etrolizumab in a Phase 2 Study in Moderate-to-Severely Active Ulcerative Colitis

Looney, Caroline, Fuh, Franklin, Tang, Meina T., Wei, Xiaohui, Keir, Mary E., Tew, Gaik W., Eastham-Anderson, Jeffrey, Diehl, Lauri, Salas, Azucena, De Hertogh, Gert, Francom, Steven, Gilbert, Houston

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 108 KB

english, 2014

78

Mo1820 IL-1β Induces Expression of Fibrosis Associated Genes in Human Primary Intestinal Myofibroblasts

Wright, Lilyan, Hackney, Jason, Faubion, William A., Diehl, Lauri, Van Lookeren-Campagne, Menno, Keir, Mary E.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 235 KB

english, 2013

79

345 Pediatric Preclinical Testing Program (PPTP) Stage 1 Evaluation of Eribulin

Smith, M., Kang, M., Lock, R., Carol, H., Gorlick, R., Kolb, A., Maris, J., Keir, S., Kurmasheva, R., Houghton, P.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 62 KB

english, 2012

80

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

Vermeire, Séverine, O'Byrne, Sharon, Keir, Mary, Williams, Marna, Lu, Timothy T, Mansfield, John C, Lamb, Christopher A, Feagan, Brian G, Panes, Julian, Salas, Azucena, Baumgart, Daniel C, Schreiber,

Journal:

Year:

2014

Language:

english

File:

PDF, 626 KB

english, 2014

81

Role of the Water–Metal Ion Bridge in Mediating Interactions between Quinolones and Escherichia coli Topoisomerase IV

Aldred, Katie J., Breland, Erin J., Vlčková, Vladislava, Strub, Marie-Paule, Neuman, Keir C., Kerns, Robert J., Osheroff, Neil

Journal:

Year:

2014

Language:

english

File:

PDF, 2.83 MB

english, 2014

82

ortho Diquaternary Aromatic Compounds. IV. Acid-catalyzed Rearrangements of Polyalkyltetralones and Related Ketones

Barclay, Lawrence Ross Coates, Young, Robert Hayworth, Adams, Keir Leigh, Foote, Helen Mary

Journal:

Canadian Journal of Chemistry

Year:

1973

Language:

english

File:

PDF, 549 KB

english, 1973

83

Cerebrospinal Fluid Apolipoprotein E Concentration Decreases after Traumatic Brain Injury

Kay, Andrew D., Petzold, Axel, Kerr, Mary, Keir, Geoff, Thompson, Ed J., Nicoll, James A.R.

Journal:

Journal of Neurotrauma

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

84

410 Pediatric Preclinical Testing Program (PPTP) Evaluation of the p53-MDM2 Antagonist MK-8242

Smith, M., Kang, M., Reynolds, P., Lock, R., Carol, H., Gorlick, R., Kolb, A., Maris, J., Keir, S., Wu, J., Kurmasheva, R., Houghton, P.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

85

412 The Pediatric Preclinical Testing Program (PPTP): Analysis of the first 10 years in vivo testing

Houghton, P., Lock, R., Carol, H., Gorlick, R., Kolb, A., Maris, J., Keir, S., Wu, J., Kang, M., Reynolds, P., Kurmasheva, R., Smith, M.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 80 KB

english, 2014

86

Initial testing (stage 1) of the investigational mTOR kinase inhibitor MLN0128 by the pediatric preclinical testing program

Kang, Min H., Reynolds, C. Patrick, Maris, John M., Gorlick, Richard, Kolb, E. Anders, Lock, Richard, Carol, Hernan, Keir, Stephen T., Wu, Jianrong, Lyalin, Dmitry, Kurmasheva, Raushan T., Houghton, P

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 72 KB

english, 2014

87

Initial testing (stage 1) of the histone deacetylase inhibitor, quisinostat (JNJ-26481585), by the Pediatric Preclinical Testing Program

Carol, Hernan, Gorlick, Richard, Kolb, E. Anders, Morton, Christopher L., Manesh, Donya Moradi, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Maris, John M., Wozniak, Amy, Hickson, Ian, Lyalin

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 1013 KB

english, 2014

88

Initial solid tumor testing (Stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program

Houghton, Peter J., Kurmasheva, Raushan T., Lyalin, Dmitry, Maris, John M., Kolb, E. Anders, Gorlick, Richard, Reynolds, C. Patrick, Kang, Min H., Keir, Stephen T., Wu, Jianrong, Smith, Malcolm A.

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

89

Early Identification of Secondary Brain Damage in Subarachnoid Hemorrhage: A Role for Glial Fibrillary Acidic Protein

Petzold, Axel, Keir, Geoffrey, Kerr, Mary, Kay, Andrew, Kitchen, Neil, Smith, Martin, Thompson, Edward J.

Journal:

Journal of Neurotrauma

Year:

2006

Language:

english

File:

PDF, 130 KB

english, 2006

90

Alterations in Cerebrospinal Fluid Apolipoprotein E and Amyloid β -Protein after Traumatic Brain Injury

Kay, Andrew D., Petzold, Axel, Kerr, Mary, Keir, Geoff, Thompson, Ed, Nicoll, James A.R.

Journal:

Journal of Neurotrauma

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

91

Synergistic Activity of PARP Inhibition by Talazoparib (BMN 673) with Temozolomide in Pediatric Cancer Models in the Pediatric Preclinical Testing Program

Smith, M. A., Reynolds, C. P., Kang, M. H., Kolb, E. A., Gorlick, R., Carol, H., Lock, R. B., Keir, S. T., Maris, J. M., Billups, C. A., Lyalin, D., Kurmasheva, R. T., Houghton, P. J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

92

Sa1145 AlphaE (αE) Integrin Protein and Gene Expression Are Augmented in the Ileum Relative to the Colon in Crohn's Disease

Ichikawa, Ryan, Eastham-Anderson, Jeffrey, Scherl, Alexis, Tew, Wei, Egen, Jackson G., Lamb, Christopher A., Mansfield, John C., Kirby, John A., Faubion, William A., O'Byrne, Sharon, Keir, Mary E.

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 688 KB

english, 2015

93

Su1220 Rectal Bleeding Accurately Reflects Level of Mucosal Inflammation in Patients With Ulcerative Colitis

O'Byrne, Sharon, Keir, Mary E., Cabanski, Christopher R., Zhao, Rui, Colombel, Jean-Frederic, Panes, Julian, Lu, Timothy, Faubion, William A., Fletcher, Joel G., Feagan, Brian G., Kulkarni, Priya, Hig

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 547 KB

english, 2015

94

Stratified medicine in inflammatory disorders: From theory to practice

Arron, Joseph R., Townsend, Michael J., Keir, Mary E., Yaspan, Brian L., Chan, Andrew C.

Journal:

Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 900 KB

english, 2015

95

Stage 2 Combination Testing of Rapamycin with Cytotoxic Agents by the Pediatric Preclinical Testing Program

Houghton, P. J., Morton, C. L., Gorlick, R., Lock, R. B., Carol, H., Reynolds, C. P., Kang, M. H., Maris, J. M., Keir, S. T., Kolb, E. A., Wu, J., Wozniak, A. W., Billups, C. A., Rubinstein, L., Smith

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

96

IFN-α-Induced Upregulation of CCR5 Leads to Expanded HIV Tropism In Vivo

Stoddart, Cheryl A., Keir, Mary E., McCune, Joseph M., Luban, Jeremy

Journal:

Year:

2010

Language:

english

File:

PDF, 959 KB

english, 2010

97

Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development

Brown, Kristine E., Chagoya, Gustavo, Kwatra, Shawn G., Yen, Timothy, Keir, Stephen T., Cooter, Mary, Hoadley, Katherine A., Rasheed, Ahmed, Lipp, Eric S., Mclendon, Roger, Ali-Osman, Francis, Bigner,

Journal:

Journal of Neurochemistry

Year:

2015

Language:

english

File:

PDF, 376 KB

english, 2015

98

Single molecule measurements of DNA helicase activity with magnetic tweezers and t-test based step-finding analysis

Seol, Yeonee, Strub, Marie-Paule, Neuman, Keir C.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

99

Effects of cortical visual impairment on navigational ability in posterior cortical atrophy and typical Alzheimer’s disease

Yong, Keir X.X., Holloway, Catherine, Carton, Amelia, Yang, Biao, Suzuki, Tatsuto, Serougne, Robin, Boampong, Derrick, Voyce, Daniel, Sullivan, Mary Pat, McCarthy, Ian, Tyler, Nick, Crutch, Sebastian

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 220 KB

english, 2015

100

Arylsulphatase A pseudo-deficiency in vascular dementia and Alzheimerʼs disease

Philpot, Michael, Lewis, Keir, Pereria, Maria Luiza, Ward, Chandra, Holmes, Clive, Lovestone, Simon, Fensom, Anthony, Seller, Mary

Journal:

Year:

1997

Language:

english

File:

PDF, 225 KB

english, 1997