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51

Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach

McConnell, Jeanette R., Buckton, Laura K., McAlpine, Shelli R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 825 KB

english, 2015

52

Blocking the heat shock response and depleting HSF-1 levels through heat shock protein 90 (hsp90) inhibition: a significant advance on current hsp90 chemotherapies

Koay, Yen Chin, McConnell, Jeanette R., Wang, Yao, McAlpine, Shelli R.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

53

Synthesis of the Natural Product Marthiapeptide A

Zhang, Yuqi, Islam, Md. Amirul, McAlpine, Shelli R.

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 567 KB

english, 2015

54

Macrocyclic Inhibitors of Hsp90

A. Johnson, Victoria, K. Singh, Erinprit, A. Nazarova, Lidia, D. Alexander, Leslie, R. McAlpine, Shelli

Journal:

Current Topics in Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 683 KB

english, 2010

55

Hydrothermal synthesis of highly luminescent blue-emitting ZnSe(S) quantum dots exhibiting low toxicity

Mirnajafizadeh, Fatemeh, Ramsey, Deborah, McAlpine, Shelli, Wang, Fan, Reece, Peter, Stride, John Arron

Journal:

Materials Science and Engineering: C

Year:

2016

Language:

english

File:

PDF, 809 KB

english, 2016

56

[Topics in Medicinal Chemistry] Heat Shock Protein Inhibitors Volume 19 ||

McAlpine, Shelli R., Edkins, Adrienne Lesley

Year:

2016

Language:

english

File:

PDF, 6.03 MB

english, 2016

57

Editorial [Hot topic: RNAi and Related Technologies: Applications in Medicinal Chemistry and Drug Discovery (Guest Editors: Keven Morris and Shelli McAlpine)]

Morris, Keven, McAlpine, Shelli

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 19 KB

english, 2009

58

Hitting a Moving Target: How Does an N -Methyl Group Impact Biological Activity?

Koay, Yen Chin, Richardson, Nicole L., Zaiter, Samantha S., Kho, Jessica, Nguyen, Sheena Y., Tran, Daniel H., Lee, Ka Wai, Buckton, Laura K., McAlpine, Shelli R.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

59

ChemInform Abstract: Sanguinamide B Analogues: Identification of Active Macrocyclic Structures.

Wahyudi, Hendra, Tantisantisom, Worawan, McAlpine, Shelli R.

Journal:

Year:

2014

File:

PDF, 17 KB

2014

60

A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response

Armstrong, Heather K., Koay, Yen Chin, Irani, Swati, Das, Rajdeep, Nassar, Zeyad D., Selth, Luke A., Centenera, Margaret M., McAlpine, Shelli R., Butler, Lisa M.

Journal:

Year:

2016

Language:

english

File:

PDF, 4.17 MB

english, 2016

61

[Topics in Medicinal Chemistry] Heat Shock Protein Inhibitors Volume 19 || Evaluating Dual Hsp90 and Hsp70 Inhibition as a Cancer Therapy

McAlpine, Shelli R., Edkins, Adrienne Lesley

Year:

2016

Language:

english

File:

PDF, 585 KB

english, 2016

62

Redefining the phenotype of Heat shock protein 90 (Hsp90) inhibitors

Wang, Yao, Koay, Yen Chin, McAlpine, Shelli Renee

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 2.54 MB

english, 2016

63

Reinventing Hsp90 Inhibitors: Blocking C-Terminal Binding Events to Hsp90 by Using Dimerized Inhibitors

Koay, Yen Chin, Wahyudi, Hendra, McAlpine, Shelli R.

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 840 KB

english, 2016

64

How Selective are Hsp90 Inhibitors for Cancer Cells over Normal Cells?

Wang, Yao, Koay, Yen Chin, McAlpine, Shelli R.

Journal:

Year:

2017

Language:

english

File:

PDF, 9.86 MB

english, 2017

65

RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles

Pietkiewicz, Adrian L., Zhang, Yuqi, Rahimi, Marwa N., Stramandinoli, Michael, Teusner, Matthew, McAlpine, Shelli R.

Journal:

ACS Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 1.14 MB

english, 2017

66

Improving the Cell Permeability of Polar Cyclic Peptides by Replacing Residues with Alkylated Amino Acids, Asparagines, and d -Amino Acids

Buckton, Laura K., McAlpine, Shelli R.

Journal:

Organic Letters

Year:

2018

Language:

english

File:

PDF, 939 KB

english, 2018

67

Converting polar cyclic peptides into membrane permeable molecules using N -methylation

Lee, Leo L. H., Buckton, Laura K., McAlpine, Shelli R.

Journal:

Peptide Science

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

68

Hsp90 Mediates Membrane Deformation and Exosome Release

Lauwers, Elsa, Wang, Yu-Chun, Gallardo, Rodrigo, Van der Kant, Rob, Michiels, Emiel, Swerts, Jef, Baatsen, Pieter, Zaiter, Samantha S., McAlpine, Shelli R., Gounko, Natalia V., Rousseau, Frederic, Sch

Journal:

Year:

2018

Language:

english

File:

PDF, 5.94 MB

english, 2018

69

Designing de novo small molecules that control Heat shock protein 70 (Hsp70) and Heat shock organizing protein (HOP) within the chaperone protein-folding machinery

Zaiter, Samantha, Huo, Yuantao, Tiew, Fong Ying, Gestwicki, Jason E., McAlpine, Shelli R

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.77 MB

english, 2018

70

Nanoparticles for Bioapplications: Study of the Cytotoxicity of Water Dispersible CdSe(S) and CdSe(S)/ZnO Quantum Dots

Mirnajafizadeh, Fatemeh, Ramsey, Deborah, McAlpine, Shelli, Wang, Fan, Stride, John

Journal:

Year:

2019

Language:

english

File:

PDF, 12.67 MB

english, 2019

71

Real time monitoring of peptide delivery in vitro using high payload pH responsive nanogels

Farazi, Shegufta, Chen, Fan, Foster, Henry, Boquiren, Raelene, McAlpine, Shelli R., Chapman, Robert

Journal:

Polymer Chemistry

Year:

2020

File:

PDF, 2.79 MB

2020

72

Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019

Zubair, Adeel S., McAlpine, Lindsay S., Gardin, Tova, Farhadian, Shelli, Kuruvilla, Deena E., Spudich, Serena

Journal:

Year:

2020

File:

PDF, 1005 KB

2020

73

Cyclic peptides as drugs for intracellular targets: the next frontier in peptide therapeutic development

Buckton, Laura K., Rahimi, Marwa N., McAlpine, Shelli Renee

Journal:

Chemistry (Weinheim an der Bergstrasse, Germany)

Year:

2020

File:

PDF, 4.14 MB

2020