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51

Mouse L Cells Expressing Human Prourokinase-Type Plasminogen Activator: Effects on Extracellular Matrix Degradation and Invasion

Jean-François Cajot, Wolf-Dieter Schleuning, Robert L. Medcalf, Jeanine Bamat, Joëlle Testuz, Liora Liebermann and Bernard Sordat

Journal:

The Journal of Cell Biology

Year:

1989

Language:

english

File:

PDF, 1.97 MB

english, 1989

52

Plasmin-dependent modulation of the blood–brain barrier: a major consideration during tPA-induced thrombolysis?

Niego, Be'eri, Medcalf, Robert L

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2014

Language:

english

File:

PDF, 701 KB

english, 2014

53

The dynamics of adult haematopoiesis in the bone and bone marrow environment

Ho, Miriel S. H., Medcalf, Robert L., Livesey, Stephen A., Traianedes, Kathy

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 515 KB

english, 2015

54

Traumatic brain injury opens blood–brain barrier to stealth liposomes via an enhanced permeability and retention (EPR)-like effect

Boyd, Ben J., Galle, Adam, Daglas, Maria, Rosenfeld, Jeffrey V., Medcalf, Robert

Journal:

Journal of Drug Targeting

Year:

2015

Language:

english

File:

PDF, 261 KB

english, 2015

55

Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier

Niego, Be'eri, Medcalf, Robert L.

Journal:

Journal of Visualized Experiments

Year:

2013

Language:

english

File:

PDF, 815 KB

english, 2013

56

A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and Apoptosis

Leung, Kin-Mei, Batey, Sarah, Rowlands, Robert, Isaac, Samine J, Jones, Phil, Drewett, Victoria, Carvalho, Joana, Gaspar, Miguel, Weller, Sarah, Medcalf, Melanie, Wydro, Mateusz M, Pegram, Robert, Mud

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 2.85 MB

english, 2015

57

Plasminogen-Stimulated Inflammatory Cytokine Production by Airway Smooth Muscle Cells Is Regulated by Annexin A2

Schuliga, Michael, Langenbach, Shenna, Xia, Yuxiu C., Qin, Chengxue, Mok, Josephine S.L., Harris, Trudi, Mackay, Graham A., Medcalf, Robert L., Stewart, Alastair G.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

58

A Coding System that Makes Sense

Robert L. Medcalf and Margaret Ratz

Journal:

Elementary English

Year:

1973

Language:

english

File:

PDF, 647 KB

english, 1973

59

Three Human Elastase-Like Genes Coordinately Expressed in the Myelomonocyte Lineage are Organized as a Single Genetic Lucus on 19pter

Michael Zimmer, Robert L. Medcalf, Thomas M. Fink, Chantal Mattmann, Peter Lichter and Dieter E. Jenne

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

60

[Methods in Enzymology] Biology of Serpins Volume 499 || Plasminogen Activator Inhibitor Type 2

Medcalf, Robert L.

Year:

2011

Language:

english

File:

PDF, 350 KB

english, 2011

61

Regulation of Human Tissue-Type Plasminogen Activator Gene Transcription by Epidermal Growth Factor and 3′,5′-Cyclic Adenosine Monophosphate

Medcalf, Robert L., Schleuning, Wolf-Dieter

Journal:

Molecular Endocrinology

Year:

1991

Language:

english

File:

PDF, 680 KB

english, 1991

62

Regulatory elements involved in constitutive and phorbol ester-inducible expression of the plasminogen activator inhibitor type 2 gene promoter

Cousin, Elisabeth, Medcalf, Robert L., Bergonzelli, Gabriela E., Kruithof, Egbert K.O.

Journal:

Nucleic Acids Research

Year:

1991

Language:

english

File:

PDF, 3.86 MB

english, 1991

63

Physiologic Concentrations of Magnesium and Placental Apoptosis

Black, Simon, Yu, Hong, Lee, Joanna, Sachchithananthan, Mythily, Medcalf, Robert L.

Journal:

Obstetrics & Gynecology

Year:

2001

Language:

english

File:

PDF, 308 KB

english, 2001

64

[Society of Petroleum Engineers SPE European Spring Meeting - Amsterdam, Netherlands (1976-04-08)] SPE European Spring Meeting - Problems Associated With the Operation of Offshore Sea Water Injection Systems

Flammang, Robert F., Medcalfe, T.M., Culligan, Paul T.

Language:

english

File:

PDF, 943 KB

english

65

[Society of Petroleum Engineers SPE European Spring Meeting - (1976.04.8-1976.04.9)] Proceedings of SPE European Spring Meeting - Problems Associated With the Operation of Offshore Sea Water Injection Systems

Flammang, Robert, Medcalfe, T.M., Culligan, Paul

Year:

1976

Language:

english

File:

PDF, 943 KB

english, 1976

66

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid

Niego, Beʼeri, Horvath, Anita, Coughlin, Paul B, Pugsley, Michael K, Medcalf, Robert L

Journal:

Blood Coagulation & Fibrinolysis

Year:

2008

Language:

english

File:

PDF, 237 KB

english, 2008

67

Fabrication of complex PDMS microfluidic structures and embedded functional substrates by one-step injection moulding

Szydzik, Crispin, Niego, Beeri, Dalzell, Geordie, Knoerzer, Markus, Ball, Florian, Nesbitt, Warwick Scott, Medcalf, Robert, Khoshmanesh, Khashayar, Mitchell, Arnan

Journal:

Year:

2016

Language:

english

File:

PDF, 1.52 MB

english, 2016

68

Hormonal regulation of haemostasis and the molecular biology of the fibrinolytic system

Grant, Peter J., Medcalf, Robert L.

Journal:

Clinical Science

Year:

1990

Language:

english

File:

PDF, 1.01 MB

english, 1990

69

Plasmin: A Modulator of Immune Function

Draxler, Dominik, Sashindranath, Maithili, Medcalf, Robert

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2016

Language:

english

File:

PDF, 286 KB

english, 2016

70

tPA Modulation of the Blood–Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS

Fredriksson, Linda, Lawrence, Daniel, Medcalf, Robert

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2016

Language:

english

File:

PDF, 475 KB

english, 2016

71

Grainyhead-like 3 ( Grhl3 ) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice

Dworkin, Sebastian, Auden, Alana, Partridge, Darren D., Daglas, Maria, Medcalf, Robert L., Mantamadiotis, Theo, Georgy, Smitha R., Darido, Charbel, Jane, Stephen M., Ting, Stephen B.

Journal:

Developmental Neurobiology

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

72

Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa

Bonnard, Thomas, Tennant, Zachary, Niego, Be'Eri, Kanojia, Ruchi, Alt, Karen, Jagdale, Shweta, Law, Lok Soon, Rigby, Sheena, Medcalf, Robert Lindsay, Peter, Karlheinz, Hagemeyer, Christoph Eugen

Journal:

Journal of the American Heart Association

Year:

2017

Language:

english

File:

PDF, 3.30 MB

english, 2017

73

Fibrinolysis: Biochemistry, Clinical Aspects, and Therapeutic Potential

Kwaan, Hau, Lisman, Ton, Medcalf, Robert

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2017

Language:

english

File:

PDF, 54 KB

english, 2017

74

Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells

Samson, Andre L., Ho, Bosco, Au, Amanda E., Schoenwaelder, Simone M., Smyth, Mark J., Bottomley, Stephen P., Kleifeld, Oded, Medcalf, Robert L.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

75

Haemostasis and innate immunity - a complementary relationship

Keragala, Charithani B., Draxler, Dominik F., McQuilten, Zoe K., Medcalf, Robert L.

Journal:

British Journal of Haematology

Year:

2017

Language:

english

File:

PDF, 512 KB

english, 2017

76

Transcriptional and posttranscriptional regulation of the plasminogen activator system

Nagamine, Yoshikuni, Muñoz-Cánoves, Pura, Medcalf, Robert L.

Journal:

Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 385 KB

english, 2005

77

Species-Specific Regulation of t-PA and PAI-1 Gene Expression in Human and Rat Astrocytes

Tjärnlund-Wolf, Anna, Hultman, Karin, Blomstrand, Fredrik, Nilsson, Michael, Medcalf, Robert L., Jern, Christina

Journal:

Gene Regulation and Systems Biology

Year:

2014

Language:

english

File:

PDF, 952 KB

english, 2014

78

LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH

Niego, Be’eri, Broughton, Brad R. S., Ho, Heidi, Sobey, Christopher G., Medcalf, Robert L.

Journal:

Fluids and Barriers of the CNS

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

79

Role of Histone Acetylation in the Stimulatory Effect of Valproic Acid on Vascular Endothelial Tissue-Type Plasminogen Activator Expression

Larsson, Pia, Ulfhammer, Erik, Magnusson, Mia, Bergh, Niklas, Lunke, Sebastian, El-Osta, Assam, Medcalf, Robert L., Svensson, Per-Arne, Karlsson, Lena, Jern, Sverker, Reitsma, Pieter H.

Journal:

Year:

2012

Language:

english

File:

PDF, 366 KB

english, 2012

80

Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin

Borg, Rachael J., Samson, Andre L., Au, Amanda E.-L., Scholzen, Anja, Fuchsberger, Martina, Kong, Ying Y., Freeman, Roxann, Mifsud, Nicole A., Plebanski, Magdalena, Medcalf, Robert L., Nishimura, Step

Journal:

Year:

2015

Language:

english

File:

PDF, 2.10 MB

english, 2015

81

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

Niego, Be’eri, Lee, Natasha, Larsson, Pia, De Silva, T. Michael, Au, Amanda E-Ling, McCutcheon, Fiona, Medcalf, Robert L., Wang, Xiaoying

Journal:

Year:

2017

Language:

english

File:

PDF, 20.25 MB

english, 2017

82

Editorial: The Role of the Plasminogen Activating System in Neurobiology

Medcalf, Robert L., Lawrence, Daniel A.

Journal:

Frontiers in Cellular Neuroscience

Year:

2016

Language:

english

File:

PDF, 227 KB

english, 2016

83

The Molecular Basis for the Aberrant Production of Plasminogen Activator Inhibitor Type 2 in THP-1 Monocytes

Katsikis, Jackie, Yu, Hong, Maurer, Fabienne, Medcalf, Robert

Journal:

Thrombosis and Haemostasis

Year:

2000

Language:

english

File:

PDF, 225 KB

english, 2000

84

Allelic imbalance of tissue-type plasminogen activator (t-PA) gene expression in human brain tissue

Tjärnlund-Wolf, Anna, Hultman, Karin, Curtis, Maurice, Faull, Richard, Medcalf, Robert, Jern, Christina

Journal:

Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 268 KB

english, 2011

85

Prothrombin G20210A is a Bifunctional Gene Polymorphism

Carter, Angela, Sachchithananthan, Mythily, Stasinopoulos, Stan, Maurer, Fabienne, Medcalf, Robert

Journal:

Thrombosis and Haemostasis

Year:

2002

File:

PDF, 243 KB

2002

86

Tranexamic acid influences the immune response, but not bacterial clearance in a model of post-traumatic brain injury pneumonia

Draxler, Dominik F, Awad, Milena M, Hanafi, Gryselda, Daglas, Maria, Ho, Heidi, Keragala, Charithani B, Galle, Adam, Roquilly, Antoine, Lyras, Dena, Sashindranath, Maithili, Medcalf, Robert Lindsay

Journal:

Journal of Neurotrauma

Year:

2019

Language:

english

File:

PDF, 1.43 MB

english, 2019

87

Human Endothelial Cell-derived Nuclear Proteins that Recognise Polymorphic DNA Elements in the von Willebrand Factor Gene Promoter Include YY1

Costa, Magdaline, Grant, Peter, Rice, Gillian, Futers, Simon, Medcalf, Robert

Journal:

Thrombosis and Haemostasis

Year:

2001

Language:

english

File:

PDF, 236 KB

english, 2001

88

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, Maria, Draxler, Dominik F., Ho, Heidi, McCutcheon, Fiona, Galle, Adam, Au, Amanda E., Larsson, Pia, Gregory, Julia, Alderuccio, Frank, Sashindranath, Maithili, Medcalf, Robert L.

Journal:

Year:

2019

Language:

english

File:

PDF, 5.72 MB

english, 2019

89

Fibrinolysis Shutdown in Trauma

Moore, Hunter B., Moore, Ernest E., Neal, Matthew D., Sheppard, Forest R., Kornblith, Lucy Z., Draxler, Dominik F., Walsh, Mark, Medcalf, Robert L., Cohen, Mitch J., Cotton, Bryan A., Thomas, Scott G.

Journal:

Anesthesia & Analgesia

Year:

2019

File:

PDF, 563 KB

2019

90

Fibrinolysis and the Immune Response in Trauma

Medcalf, Robert L., Keragala, Charithani B., Draxler, Dominik F.

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2020

Language:

english

File:

PDF, 445 KB

english, 2020

91

Editorial: Fibrinolysis in Immunity

Kolev, Krasimir, Medcalf, Robert L.

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 120 KB

2020

92

Fibrinolysis and tranexamic acid: mechanistic principles

Draxler, Dominik F., Medcalf, Robert L.

Journal:

ANZ Journal of Surgery

Year:

2020

File:

PDF, 211 KB

2020

93

Fibrinolysis and COVIDâ19: a plasmin paradox

Medcalf, Robert L., Keragala, Charithani B., Myles, Paul S.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2020

File:

PDF, 5.82 MB

2020

94

Sexâdependent effects of tranexamic acid on bloodâbrain barrier permeability and the immuneÂ response following traumatic brain injury in mice

Daglas, Maria, Galle, Adam, Draxler, Dominik F., Ho, Heidi, Liu, Zikou, Sashindranath, Maithili, Medcalf, Robert L.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2020

File:

PDF, 15.50 MB

2020

95

Fibrinolysis and COVIDâ19: a tale of two sites?

Keragala, Charithani B., Medcalf, Robert L., Myles, Paul S.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2020

File:

PDF, 2.60 MB

2020

96

Tissue-Type Plasminogen Activator and Tenecteplase-Mediated Increase in Blood Brain Barrier Permeability Involves Cell Intrinsic Complement

Keragala, Charithani B., Woodruff, Trent M., Liu, Zikou, Niego, Be'eri, Ho, Heidi, McQuilten, Zoe, Medcalf, Robert L.

Journal:

Frontiers in Neurology

Year:

2020

File:

PDF, 1.45 MB

2020

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