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51

Control of tissue-localized immune responses by human regulatory T cells

Pesenacker, Anne M., Broady, Raewyn, Levings, Megan K.

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 441 KB

english, 2015

52

T regulatory cell therapy in transplantation

MacDonald, Katherine G., Orban, Paul C., Levings, Megan K.

Journal:

Current Opinion in Organ Transplantation

Year:

2012

Language:

english

File:

PDF, 227 KB

english, 2012

53

Generation of Potent and Stable Human CD4+ T Regulatory Cells by Activation-independent Expression of FOXP3

Allan, Sarah E, Alstad, Alicia N, Merindol, Natacha, Crellin, Natasha K, Amendola, Mario, Bacchetta, Rosa, Naldini, Luigi, Roncarolo, Maria Grazia, Soudeyns, Hugo, Levings, Megan K

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 505 KB

english, 2008

54

The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells

Levings, Megan K., Bacchetta, Rosa, Schulz, Ute, Roncarolo, Maria Grazia

Journal:

International Archives of Allergy and Immunology

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

55

Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells

Weiner, Joshua, Duran-Struuck, Raimon, Zitsman, Jonah, Buhler, Leo, Sondermeijer, Hugo, McMurchy, Alicia N., Levings, Megan K., Sykes, Megan, Griesemer, Adam

Journal:

Transplantation Direct

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

56

Inflammation-Driven Reprogramming of CD4+Foxp3+ Regulatory T Cells into Pathogenic Th1/Th17 T Effectors Is Abrogated by mTOR Inhibition in vivo

Yurchenko, Ekaterina, Shio, Marina T., Huang, Tony C., Da Silva Martins, Maria, Szyf, Moshe, Levings, Megan K., Olivier, Martin, Piccirillo, Ciriaco A., Unutmaz, Derya

Journal:

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

57

TH17 Cells in Autoimmunity and Immunodeficiency: Protective or Pathogenic?

Marwaha, Ashish K., Leung, Nicole J., McMurchy, Alicia N., Levings, Megan K.

Journal:

Frontiers in Immunology

Year:

2012

Language:

english

File:

PDF, 663 KB

english, 2012

58

The Environment of Regulatory T Cell Biology: Cytokines, Metabolites, and the Microbiome

Hoeppli, Romy E., Wu, Dan, Cook, Laura, Levings, Megan K.

Journal:

Frontiers in Immunology

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

59

A Treg gene signature is a specific and sensitive biomarker to identify children with new onset type 1 diabetes

Pesenacker, Anne M, Wang, Adele Y, Singh, Amrit, Gillies, Jana, Kim, Young W, Piccirillo, Ciriaco A., Nguyen, Duc, Haining, W Nicholas, Tebbutt, Scott J, Panagiotopoulos, Constadina, Levings, Megan K

Journal:

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016

60

Phenotype, Function and Expansion of Regulatory T Cells in the Cynomolgus Macaque (Macaca fascicularis)

Guallart, Paula Alonso, Zitsman, Jonah, Sondermeijer, Hugo, Bühler, Leo, Ovanez, Christopher, McMurchy, Alicia, Levings, Megan, Sykes, Megan, Duran-Struuck, Raimon

Journal:

Biology of Blood and Marrow Transplantation

Year:

2015

Language:

english

File:

PDF, 72 KB

english, 2015

61

CCL22 Prevents Rejection of Mouse Islet Allografts and Induces Donor-Specific Tolerance

Montane, Joel, Obach, Merce, Alvarez, Sigrid, Bischoff, Loraine, Dai, Derek L., Soukhatcheva, Galina, Priatel, John J., Hardenberg, Gijs, Levings, Megan K., Tan, Rusung, Orban, Paul C., Verchere, C. B

Journal:

Cell Transplantation

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

62

SPIE Proceedings [SPIE SPIE BiOS: Biomedical Optics - San Jose, CA (Saturday 24 January 2009)] Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVI - Quantifying colocalization of a conditionally active transcription factor FOXP3 in three-dimensional cellular space

Abraham, Thomas, Conchello, Jose-Angel, Cogswell, Carol J., Allan, Sarah E., Levings, Megan K., Wilson, Tony

Year:

2009

Language:

english

File:

PDF, 669 KB

english, 2009

63

P-190 Use of a Novel Activation Assay to Detect Increased Flagellin-Reactive CD4+ T cells in Peripheral Blood from Crohnʼs Disease Patients

Rosa, Garcia, Megan, Himmel, Jamie, Koenekoop, Ernest, Seidman, Megan, Levings, Theodore, Steiner

Journal:

Inflammatory Bowel Diseases

Year:

2013

Language:

english

File:

PDF, 61 KB

english, 2013

64

The role of FOXP3 in autoimmunity

Pesenacker, Anne M, Cook, Laura, Levings, Megan K

Journal:

Current Opinion in Immunology

Year:

2016

Language:

english

File:

PDF, 602 KB

english, 2016

65

Nonnative Species in British Columbia Eelgrass Beds Spread via Shellfish Aquaculture and Stay for the Mild Climate

Mach, Megan E., Levings, Colin D., Chan, Kai M. A.

Journal:

Estuaries and Coasts

Year:

2017

Language:

english

File:

PDF, 944 KB

english, 2017

66

Circulating gluten-specific FOXP3 + CD39 + regulatory T cells have impaired suppressive function in patients with celiac disease

Cook, Laura, Munier, C. Mee Ling, Seddiki, Nabila, van Bockel, David, Ontiveros, Noé, Hardy, Melinda Y., Gillies, Jana K., Levings, Megan K., Reid, Hugh H., Petersen, Jan, Rossjohn, Jamie, Anderson, R

Journal:

Journal of Allergy and Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 2.66 MB

english, 2017

67

Harnessing Advances in T Regulatory Cell Biology for Cellular Therapy in Transplantation

Lam, Avery J, Hoeppli, Romy E, Levings, Megan K

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 2.03 MB

english, 2017

68

Regulatory T-cells drive immune dysfunction in CLL

Lad, Deepesh, Hoeppli, Romy, Huang, Qing, Garcia, Rosa, Xu, Lixin, Toze, Cynthia, Broady, Raewyn, Levings, Megan

Journal:

Leukemia and Lymphoma

Year:

2017

Language:

english

File:

PDF, 885 KB

english, 2017

69

A Novel Whole Blood Assay Detects Flagellin-Specific CD4 + T Cells in Patients with Inflammatory Bowel Disease

Cook, Laura, Wong, May Q., Garcia, Rosa, Himmel, Megan E., Bressler, Brian, Seidman, Ernest G., Steiner, Theodore S., Levings, Megan K.

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

70

Evaluating the Role of Tregs in the Progression of Multiple Myeloma

Lad, Deeepesh, Broady, Raewyn, Huang, Jessica, Hoeppli, Romy, Pesenacker, Anne, Garcia, Rosa, Xu, Lixin, Levings, Megan, Song, Kevin

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2017

Language:

english

File:

PDF, 80 KB

english, 2017

71

Antigen-specific regulatory T cells: are police CARs the answer?

Dawson, Nicholas A.J., Levings, Megan K.

Journal:

Translational Research

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

72

Thymic progenitors of TCRαβ + CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development

Golec, Dominic P., Hoeppli, Romy E., Henao Caviedes, Laura M., McCann, Jillian, Levings, Megan K., Baldwin, Troy A.

Journal:

Journal of Experimental Medicine

Year:

2017

Language:

english

File:

PDF, 2.27 MB

english, 2017

73

Migration Capacity of Thymic Regulatory T Cells can be Tuned by Expansion in Cytokine-Enriched Culture Conditions

Hoeppli, Romy E., Dijke, Esmé, Campbell, Andrew, West, Lori J., Levings, Megan K.

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 5.92 MB

english, 2017

74

Standardized Immunophenotyping in the Canadian National Transplant Research Program

Ivison, Sabine, Janmohamed, Salima, Malek, Mehrnoush, Garcia, Rosa, Broady, Raewyn, Halpin, Anne, Richaud, Manon, Brant, Rollin, Delisle, Jean-Sebastien, West, Lori, Brinkman, Ryan R., Levings, Megan

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 4.00 MB

english, 2017

75

Thymus-Derived Treg Infusion to Prevent Graft Rejection in Heart-Transplanted Children

Bernaldo de Quirós, Esther, Pérez, Verónica A., Clemente, Maribel, Gil-Jaurena, Juan Miguel, González, María Teresa, Pion, Marjorie, Lombardi, Giovanna, West, Lori J., Levings, Megan, Correa-Rocha, Ra

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 5.92 MB

english, 2017

76

Adipose-tissue regulatory T cells: Critical players in adipose-immune crosstalk

Becker, Maike, Levings, Megan K., Daniel, Carolin

Journal:

European Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

77

Biomarker-guided stratification of autoimmune patients for biologic therapy

Ivison, Sabine, des Rosiers, Christine, Lesage, Sylvie, Rioux, John D, Levings, Megan K

Journal:

Current Opinion in Immunology

Year:

2017

Language:

english

File:

PDF, 436 KB

english, 2017

78

OR42 Expanded thymic regulatory T cells (Tregs) have low class I HLA expression levels and are HLA-DR negative – Potential for ‘Off-The-Shelf’ Cellular Therapy?

Dijke, Esme, Hoeppli, Romy, Larsen, Ingrid, Rebeyka, Ivan, Ross, David, Levings, Megan, West, Lori

Journal:

Human Immunology

Year:

2017

Language:

english

File:

PDF, 33 KB

english, 2017

79

Guiding regulatory T cells to the allograft

Lamarche, Caroline, Levings, Megan K.

Journal:

Current Opinion in Organ Transplantation

Year:

2017

Language:

english

File:

PDF, 310 KB

english, 2017

80

An optimized method to measure human FOXP3 + regulatory T cells from multiple tissue types using mass cytometry

Dawson, Nicholas A. J., Lam, Avery J., Cook, Laura, Hoeppli, Romy E., Broady, Raewyn, Pesenacker, Anne M., Leving, Megan K.

Journal:

European Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

81

SHIP-Deficient Dendritic Cells, Unlike Wild Type Dendritic Cells, Suppress T Cell Proliferation via a Nitric Oxide-Independent Mechanism

Antignano, Frann, Hamilton, Melisa, Patterson, Scott, Ho, Victor, Cohen, Carla, Levings, Megan K., Krystal, Gerald, Fritz, Jörg Hermann

Journal:

Year:

2011

Language:

english

File:

PDF, 579 KB

english, 2011

82

Transcriptome Analysis Reveals Markers of Aberrantly Activated Innate Immunity in Vitiligo Lesional and Non-Lesional Skin

Yu, Richard, Broady, Raewyn, Huang, Yuanshen, Wang, Yang, Yu, Jie, Gao, Min, Levings, Megan, Wei, Shencai, Zhang, Shengquan, Xu, Aie, Su, Mingwan, Dutz, Jan, Zhang, Xuejun, Zhou, Youwen, Rich, Benjami

Journal:

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

83

The Role of the PI3K Signaling Pathway in CD4+ T Cell Differentiation and Function

Han, Jonathan M., Patterson, Scott J., Levings, Megan K.

Journal:

Frontiers in Immunology

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

84

Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells

Dawson, Nicholas A. J., Vent-Schmidt, Jens, Levings, Megan K.

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 149 KB

english, 2017

85

CD4+ T Cells Specific for C. difficile Toxins are a Marker of Patients with Active Relapsing Disease

Cook, Laura, Wong, May, Rees, William, Lau, Torey, Levings, Megan, Steiner, Theodore

Journal:

Open Forum Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 541 KB

english, 2017

86

Evaluating the role of Tregs in the progression of multiple myeloma

Lad, Deepesh, Huang, Qing, Hoeppli, Romy, Garcia, Rosa, Xu, Lixin, Levings, Megan, Song, Kevin, Broady, Raewyn

Journal:

Leukemia and Lymphoma

Year:

2019

Language:

english

File:

PDF, 1.65 MB

english, 2019

87

Innate Control of Tissue-Reparative Human Regulatory T Cells

Lam, Avery J., MacDonald, Katherine N., Pesenacker, Anne M., Juvet, Stephen C., Morishita, Kimberly A., Bressler, Brian, Pan, James G., Sidhu, Sachdev S., Rioux, John D., Levings, Megan K.

Journal:

The Journal of Immunology

Year:

2019

Language:

english

File:

PDF, 3.88 MB

english, 2019

88

Methods to manufacture regulatory T cells for cell therapy

MacDonald, Katherine N., Piret, James M., Levings, Megan K

Journal:

Clinical & Experimental Immunology

Year:

2019

File:

PDF, 531 KB

2019

89

Methods to manufacture regulatory T cells for cell therapy

MacDonald, Katherine N., Piret, James M., Levings, Megan K

Journal:

Clinical & Experimental Immunology

Year:

2019

Language:

english

File:

PDF, 531 KB

english, 2019

90

A New Mechanism of Action in Human and Mouse Treg Cells: The Ke(y)to Suppression

Wu, Dan, Levings, Megan K.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.03 MB

english, 2019

91

Eosinophilic pneumonia: A rare manifestation of amiodarone toxicity diagnosed using traditional bronchoscopy

LeVee, Alexis, Trieu, Megan, Bhattacharyya, Sarathi, Sandhu, Gurveen

Journal:

Respiratory Medicine Case Reports

Year:

2019

Language:

english

File:

PDF, 892 KB

english, 2019

92

A New Mechanism of Action in Human and Mouse Treg Cells: The Ke(y)to Suppression

Wu, Dan, Levings, Megan K.

Journal:

Year:

2019

File:

PDF, 1.03 MB

2019

93

Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor

MacDonald, Katherine G., Hoeppli, Romy E., Huang, Qing, Gillies, Jana, Luciani, Dan S., Orban, Paul C., Broady, Raewyn, Levings, Megan K.

Journal:

The Journal of clinical investigation

Year:

2016

Language:

english

File:

PDF, 2.01 MB

english, 2016

94

OR12 Expansion conditions affect human leukocyte antigens (HLA) Class II expression on thymic regulatory T cells (TREGS)

Dijke, Esme, Ellis, Tess, Larsen, Ingrid, Rebeyka, Ivan, Freed, Darren, Al Aklabi, Mohammed, Levings, Megan, West, Lori

Journal:

Human Immunology

Year:

2019

Language:

english

File:

PDF, 416 KB

english, 2019

95

OR12 Expansion conditions affect human leukocyte antigens (HLA) Class II expression on thymic regulatory T cells (TREGS)

Dijke, Esme, Ellis, Tess, Larsen, Ingrid, Rebeyka, Ivan, Freed, Darren, Al Aklabi, Mohammed, Levings, Megan, West, Lori

Journal:

Human Immunology

Year:

2019

File:

PDF, 416 KB

2019

96

Ectopic germline recombination activity of the widely‐used Foxp3‐YFP‐Cre mouse: a case‐report

Wu, Dan, Huang, Qing, Orban, Paul C, Levings, Megan K

Journal:

Year:

2019

Language:

english

File:

PDF, 12.90 MB

english, 2019

97

Ectopic germline recombination activity of the widely‐used Foxp3‐YFP‐Cre mouse: a case‐report

Wu, Dan, Huang, Qing, Orban, Paul C, Levings, Megan K

Journal:

Year:

2019

File:

PDF, 12.90 MB

2019

98

Analysis of flagellin-specific adaptive immunity reveals links to dysbiosis in patients with Inflammatory Bowel Disease

Cook, Laura, Lisko, Daniel J., Wong, May Q., Garcia, Rosa V., Himmel, Megan E., Seidman, Ernest G., Bressler, Brian, Levings, Megan K., Steiner, Theodore S.

Journal:

CMGH Cellular and Molecular Gastroenterology and Hepatology

Year:

2019

Language:

english

File:

PDF, 2.99 MB

english, 2019

99

Analysis of flagellin-specific adaptive immunity reveals links to dysbiosis in patients with Inflammatory Bowel Disease

Cook, Laura, Lisko, Daniel J., Wong, May Q., Garcia, Rosa V., Himmel, Megan E., Seidman, Ernest G., Bressler, Brian, Levings, Megan K., Steiner, Theodore S.

Journal:

CMGH Cellular and Molecular Gastroenterology and Hepatology

Year:

2019

File:

PDF, 2.99 MB

2019

100

Human Regulatory T Cell Potential for Tissue Repair Via IL-33/ST2 and Amphiregulin

Lam, Avery J, Huang, Haiming, Pan, James G, Sidhu, Sachdev S, Charron, Guy, Ivison, Sabine M, Rioux, John D, Consortium, iGenoMed, Levings, Megan K

Journal:

Transplantation Journal

Year:

2018

File:

PDF, 92 KB

2018