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51

BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML

Zhang, Susu, Zhao, Yue, Heaster, Tiffany M., Fischer, Melissa A., Stengel, Kristy R., Zhou, Xiaofan, Ramsey, Haley, Zhou, Ming-Ming, Savona, Michael R., Skala, Melissa C., Hiebert, Scott W.

Journal:

Journal of Cellular Biochemistry

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

52

Splenomegaly Segmentation on Multi-modal MRI using Deep Convolutional Networks

Huo, Yuankai, Xu, Zhoubing, Bao, Shunxing, Bermudez, Camilo, Moon, Hyeonsoo, Parvathaneni, Prasanna, Moyo, Tamara K., Savona, Michael R., Assad, Albert, Abramson, Richard G., Landman, Bennett A.

Journal:

IEEE Transactions on Medical Imaging

Year:

2018

Language:

english

File:

PDF, 3.36 MB

english, 2018

53

Challenges in Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)

Smith, Brianna N., Savona, Michael, Komrokji, Rami S.

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2018

Language:

english

File:

PDF, 464 KB

english, 2018

54

The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5′ and 3′ ends of genes

Sampathi, Shilpa, Acharya, Pankaj, Zhao, Yue, Wang, Jing, Stengel, Kristy R, Liu, Qi, Savona, Michael R, Hiebert, Scott W

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 7.34 MB

english, 2019

55

An oral fixed-dose combination of decitabine and cedazuridine in myelodysplastic syndromes: a multicentre, open-label, dose-escalation, phase 1 study

Savona, Michael R, Odenike, Olatoyosi, Amrein, Philip C, Steensma, David P, DeZern, Amy E, Michaelis, Laura C, Faderl, Stefan, Harb, Wael, Kantarjian, Hagop, Lowder, James, Oganesian, Aram, Azab, Moha

Journal:

The Lancet Haematology

Year:

2019

File:

PDF, 468 KB

2019

56

Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study

Wei, Andrew H., Strickland, Stephen A., Hou, Jing-Zhou, Fiedler, Walter, Lin, Tara L., Walter, Roland B., Enjeti, Anoop, Tiong, Ing Soo, Savona, Michael, Lee, Sangmin, Chyla, Brenda, Popovic, Relja, S

Journal:

Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 721 KB

english, 2019

57

An oral fixed-dose combination of decitabine and cedazuridine in myelodysplastic syndromes: a multicentre, open-label, dose-escalation, phase 1 study

Savona, Michael R, Odenike, Olatoyosi, Amrein, Philip C, Steensma, David P, DeZern, Amy E, Michaelis, Laura C, Faderl, Stefan, Harb, Wael, Kantarjian, Hagop, Lowder, James, Oganesian, Aram, Azab, Moha

Journal:

The Lancet Haematology

Year:

2019

Language:

english

File:

PDF, 468 KB

english, 2019

58

Proposed diagnostic criteria for classical CMML, CMML variants and pre-CMML conditions

Valent, Peter, Orazi, Attilio, Savona, Michael R., Patnaik, Mrinal M., Onida, Francesco, van de Loosdrecht, Arjan A., Haase, Detlef, Haferlach, Torsten, Elena, Chiara, Pleyer, Lisa, Kern, Wolfgang, Pe

Journal:

Year:

2019

Language:

english

File:

PDF, 546 KB

english, 2019

59

Incorporating Precision BH3 Warheads Into the Offensive Against Acute Myeloid Leukemia

Savona, Michael R., Wei, Andrew H.

Journal:

Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 494 KB

english, 2019

60

A Phase 1b/2 Study of Oprozomib in Patients With Advanced Multiple Myeloma and Waldenström Macroglobulinemia

Ghobrial, Irene M., Vij, Ravi, Siegel, David S., Badros, Ashraf Z, Kaufman, Jonathan L, Raje, Noopur S, Jakubowiak, Andrzej J., Savona, Michael R., Obreja, Mihaela, Berdeja, Jesus G

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 1.41 MB

english, 2019

61

Incorporating Precision BH3 Warheads Into the Offensive Against Acute Myeloid Leukemia

Savona, Michael R., Wei, Andrew H.

Journal:

Journal of Clinical Oncology

Year:

2019

File:

PDF, 494 KB

2019

62

A Phase 1b/2 Study of Oprozomib in Patients With Advanced Multiple Myeloma and Waldenström Macroglobulinemia

Ghobrial, Irene M., Vij, Ravi, Siegel, David S., Badros, Ashraf Z, Kaufman, Jonathan L, Raje, Noopur S, Jakubowiak, Andrzej J., Savona, Michael R., Obreja, Mihaela, Berdeja, Jesus G

Journal:

Clinical Cancer Research

Year:

2019

File:

PDF, 1.41 MB

2019

63

Mitochondrial Homeostasis in AML and Gasping for Response in Resistance to BCL2 Blockade

Savona, Michael R., Rathmell, Jeffrey C.

Journal:

Cancer Discovery

Year:

2019

Language:

english

File:

PDF, 2.82 MB

english, 2019

64

Symptom Burden and Blood Counts in Patients With Polycythemia Vera in the United States: An Analysis From the REVEAL Study

Grunwald, Michael R., Burke, John M., Kuter, David J., Gerds, Aaron T., Stein, Brady, Walshauser, Mark A., Parasuraman, Shreekant, Colucci, Philomena, Paranagama, Dilan, Savona, Michael R., Mesa, Rube

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2019

Language:

english

File:

PDF, 1.21 MB

english, 2019

65

The Role of DNA Methyltransferase Inhibitors in the Modern Therapy of MDS

Savona, Michael R.

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2019

Language:

english

File:

PDF, 60 KB

english, 2019

66

The evolving role of next generation sequencing in myelodysplastic syndromes

Spaulding, Travis P., Stockton, Shannon S., Savona, Michael R.

Journal:

British Journal of Haematology

Year:

2019

Language:

english

File:

PDF, 669 KB

english, 2019

67

The evolving role of next generation sequencing in myelodysplastic syndromes

Spaulding, Travis P., Stockton, Shannon S., Savona, Michael R.

Journal:

British Journal of Haematology

Year:

2019

File:

PDF, 669 KB

2019

68

Evidence of vaccinia dissemination despite lack of major reaction following smallpox vaccination

Delacruz, Wilfred P., Savona, Michael R., Thornton, Jennifer A., Danaher, Patrick J.

Journal:

Year:

2019

File:

PDF, 250 KB

2019

69

Evaluation of the bioequivalence and food effect on the bioavailability of CC-486 (oral azacitidine) tablets in adult patients with cancer

Babiker, Hani M., Milhem, Mohammed, Aisner, Joseph, Edenfield, William, Shepard, Dale, Savona, Michael, Iyer, Swaminathan, Abdelrahim, Maen, Beach, C. L., Skikne, Barry, Laille, Eric, Tsai, Kao-Tai, H

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2020

File:

PDF, 804 KB

2020

70

Correction to: Evaluation of the bioequivalence and food effect on the bioavailability of CC-486 (oral azacitidine) tablets in adult patients with cancer

Babiker, Hani M., Milhem, Mohammed, Aisner, Joseph, Edenfield, William, Shepard, Dale, Savona, Michael, Iyer, Swaminathan, Abdelrahim, Maen, Beach, C. L., Skikne, Barry, Laille, Eric, Tsai, Kao-Tai, H

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2020

Language:

english

File:

PDF, 488 KB

english, 2020

71

Oral Azacitidine and Cedazuridine Approximate Parenteral Azacitidine Efficacy in Murine Model

Ramsey, Haley E., Oganesian, Aram, Gorska, Agnieszka E., Fuller, Londa, Arrate, Maria, Boyd, Kelli, Keer, Harold, Azab, Mohammad, Savona, Michael R.

Journal:

Targeted Oncology

Year:

2020

Language:

english

File:

PDF, 1.58 MB

english, 2020

72

Dasatinib vs. imatinib in patients with chronic myeloid leukemia in chronic phase (CML-CP) who have not achieved an optimal response to 3 months of imatinib therapy: the DASCERN randomized study

Cortes, Jorge E., Jiang, Qian, Wang, Jianxiang, Weng, Jianyu, Zhu, Huanling, Liu, Xiaoli, Hochhaus, Andreas, Kim, Dong-Wook, Radich, Jerald, Savona, Michael, Martin-Regueira, Patricia, Sy, Oumar, Gurn

Journal:

Year:

2020

File:

PDF, 1022 KB

2020

73

Special Considerations in the Management of Patients with Myelodysplastic Syndrome / Myeloproliferative Neoplasm Overlap Syndromes During the SARSâCoV â2 Pandemic

Patnaik, Mrinal M., Lasho, Terra, Padron, Eric, McCullough, Kristen, Alâkali, Aref, Tefferi, Ayalew, Zeidan, Amer M., Gangat, Naseema, Savona, Michael, Steensma, David P., Solary, Eric

Journal:

American Journal of Hematology

Year:

2020

File:

PDF, 2.85 MB

2020

74

Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia

Johnston, Gretchen, Ramsey, Haley E., Liu, Qi, Wang, Jing, Stengel, Kristy R., Sampathi, Shilpa, Acharya, Pankaj, Arrate, Maria, Stubbs, Matthew C., Burn, Timothy, Savona, Michael R., Hiebert, Scott W

Journal:

Year:

2020

File:

PDF, 641 KB

2020

75

Establishing specific response criteria for MDS/MPN - Getting closer to reality?

Villaume, Matthew T., Savona, Michael R.

Journal:

Best Practice & Research Clinical Haematology

Year:

2020

File:

PDF, 203 KB

2020

76

Transplant Referral Patterns for Patients (Pts) with Newly Diagnosed (ND) Higher-Risk (HR) Myelodysplastic Syndromes (MDS), and European Leukemianet (ELN) 2010 Intermediate-Risk (IR) or Adverse-Risk (AR) Acute Myeloid Leukemia (AML) in the ConnectÂ® MDS/AML Registry

Tomlinson, Benjamin, de Lima, Marcos, Cogle, Christopher R., Thompson, Michael A., Grinblatt, David L., Pollyea, Daniel A., Komrokji, Rami, Roboz, Gail J., Savona, Michael R., Sekeres, Mikkael A., Fli

Journal:

Biology of Blood and Marrow Transplantation

Year:

2020

File:

PDF, 341 KB

2020

77

Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

Zeidan, Amer M, Boddu, Prajwal C, Patnaik, Mrinal M, Bewersdorf, Jan Philipp, Stahl, Maximilian, Rampal, Raajit K, Shallis, Rory, Steensma, David P, Savona, Michael R, Sekeres, Mikkael A, Roboz, Gail

Journal:

The Lancet Haematology

Year:

2020

File:

PDF, 147 KB

2020

78

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study

Stein, Eytan M., DiNardo, Courtney D., Fathi, Amir T., Mims, Alice S., Pratz, Keith W, Savona, Michael R, Stein, Anthony S., Stone, Richard M., Winer, Eric S, Seet, Christopher S, DÃ¶hner, Hartmut, Po

Journal:

Year:

2020

File:

PDF, 567 KB

2020