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1

Early management of severe traumatic brain injury

Jeffrey V Rosenfeld, Andrew I Maas, Peter Bragge, M Cristina Morganti-Kossmann, Geoffrey T Manley, Russell L Gruen

Journal:

Year:

2012

Language:

english

File:

PDF, 233 KB

english, 2012

2

Involvement of Pro- and Anti-Inflammatory Cytokines and Chemokines in the Pathophysiology of Traumatic Brain Injury

Jenna M. Ziebell, Maria Cristina Morganti-Kossmann

Journal:

Neurotherapeutics

Year:

2010

Language:

english

File:

PDF, 806 KB

english, 2010

3

The duality of the inflammatory response to traumatic brain injury

Philipp M. Lenzlinger, Maria-Cristina Morganti-Kossmann, Helmut L. Laurer, Tracy K. McIntosh

Journal:

Molecular Neurobiology

Year:

2001

Language:

english

File:

PDF, 148 KB

english, 2001

4

Traumatic Brain and Spinal Cord Injury (Challenges and Developments) || Global epidemiology of traumatic spinal cord injury

Morganti-Kossmann, Cristina, Raghupathi, Ramesh, Maas, Andrew

Year:

2012

Language:

english

File:

PDF, 255 KB

english, 2012

5

sICAM-1 and TNF-α induce MIP-2 with distinct kinetics in astrocytes and brain microvascular endothelial cells

Viviane I. Otto, Ulrike E. Heinzel-Pleines, Sergio M. Gloor, Otmar Trentz, Thomas Kossmann, Maria Cristina Morganti-Kossmann

Journal:

Journal of Neuroscience Research

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

6

Upregulation of ICAM-1 and MCP-1 but not of MIP-2 and sensorimotor deficit in response to traumatic axonal injury in rats

Mario Rancan, Viviane I. Otto, Volkmar H.J. Hans, Irene Gerlach, Reinhard Jork, Otmar Trentz, Thomas Kossmann, Maria C. Morganti-Kossmann

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 287 KB

english, 2001

7

Neurogenesis and glial proliferation are stimulated following diffuse traumatic brain injury in adult rats

Nicole Bye, Sarah Carron, Xiaodi Han, Doreen Agyapomaa, Si Yun Ng, Edwin Yan, Jeffrey V. Rosenfeld, M. Cristina Morganti-Kossmann

Journal:

Journal of Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

8

The production of macrophage inflammatory protein-2 induced by soluble intercellular adhesion molecule-1 in mouse astrocytes is mediated by src tyrosine kinases and p42/44 mitogen-activated protein kinase

Vivianne I. Otto, Sergio M. Gloor, Stefan Frentzel, Urs Gilli, Emerita Ammann, Andreas E. Hein, Gerd Folkers, Otmar Trentz, Thomas Kossmann, Maria C. Morganti-Kossmann

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 263 KB

english, 2002

9

Neurotransmitters in cerebrospinal fluid reflect pathological activity

J. F. STOVER, U. E. PLEINES, M. C. MORGANTI-KOSSMANN, T. KOSSMANN, K. LOWITZSCH, O. S. KEMPSKI

Journal:

European Journal of Clinical Investigation

Year:

1997

Language:

english

File:

PDF, 199 KB

english, 1997

10

Traumatic Brain Injury Increases β-Amyloid Peptide 1-42 in Cerebrospinal Fluid

Charlotte A. Raby, Maria C. Morganti-Kossmann, Thomas Kossmann, Philip F. Stahel, M. Desiree Watson, Lori M. Evans, Pankaj D. Mehta, Katharyn Spiegel, Yu-Min Kuo, Alex E. Roher, Mark R. Emmerling

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 557 KB

english, 1998

11

Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury

Edwin B Yan, Sarah C Hellewell, Bo-Michael Bellander, Doreen A Agyapomaa, M Cristina Morganti-Kossmann

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

12

Low T3Syndrome in Head-Injured Patients is Associated with Prolonged Suppression of Markers of Cell-Mediated Immune Response

Volkmar H. Hans*, Philipp M. Lenzlinger*, Helen I. Joller-Jemelka, Maria C. Morganti-Kossmann, Thomas Kossmann

Journal:

European Journal of Trauma and Emergency Surgery

Year:

2005

Language:

english

File:

PDF, 476 KB

english, 2005

13

Neurochemical alterations and current pharmacological strategies in the treatment of traumatic brain injury

T. Kossmann, P. M. Lenzlinger, J. F. Stover, R. Stocker, M. C. Morganti-Kossmann, O. Trentz

Journal:

Der Unfallchirurg

Year:

1997

Language:

german

File:

PDF, 724 KB

german, 1997

14

Neue Wege in der Polytraumaforschung Ergebnisse einer Arbeitstagung auf Schloß Reisensburg, 27./28.02.2000

F. Gebhard, U.C. Liener, U. Obertacke, M.C. Morganti-Kossmann, U.B. Brückner, L. Kinzl

Journal:

Der Unfallchirurg

Year:

2001

Language:

german

File:

PDF, 82 KB

german, 2001

15

Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients

John F. Stover, Ulrike E. Pleines, Maria C. Morganti-Kossmann, Reto Stocker, Oliver S. Kempski, T. Kossmann

Journal:

Psychopharmacology

Year:

1999

Language:

english

File:

PDF, 69 KB

english, 1999

16

Changes in blood–brain barrier permeability to large and small molecules following traumatic brain injury in mice

M. D. Habgood, N. Bye, K. M. Dziegielewska, C. J. Ek, M. A. Lane, A. Potter, C Morganti-Kossmann, N. R. Saunders

Journal:

European Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 374 KB

english, 2007

17

Traumatic Brain Injury Elevates the Alzheimer's Amyloid Peptide Aβ42 in Human CSF: A Possible Role for Nerve Cell Injury

M. R. EMMERLING, M. C. MORGANTI-KOSSMANN, T. KOSSMANN, P. F. STAHEL, M. D. WATSON, L. M. EVANS, P. D. MEHTA, K. SPIEGEL, Y.-M. KUO, A. E. ROHER, C. A. RABY

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 182 KB

english, 2000

18

Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks

Semple, Bridgette D, Kossmann, Thomas, Morganti-Kossmann, Maria Cristina

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2009

Language:

english

File:

PDF, 604 KB

english, 2009

19

Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2−/− mice

Semple, Bridgette D, Bye, Nicole, Rancan, Mario, Ziebell, Jenna M, Morganti-Kossmann, M Cristina

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2009

Language:

english

File:

PDF, 838 KB

english, 2009

20

Detection of erythropoietin in human liquor: Intrinsic erythropoietin production in the brain

Marti, Hugo H, Gassmann, Max, Wenger, Roland H, Kvietikova, Ivica, Morganti-Kossmann, Maria Cristina, Kossmann, Thomas, Trentz, Otmar, Bauer, Christian

Journal:

Kidney International

Year:

1997

Language:

english

File:

PDF, 260 KB

english, 1997

21

Endogenous melatonin increases in cerebrospinal fluid of patients after severe traumatic brain injury and correlates with oxidative stress and metabolic disarray

Seifman, Marc A, Adamides, Alexios A, Nguyen, Phuong N, Vallance, Shirley A, Cooper, David James, Kossmann, Thomas, Rosenfeld, Jeffrey V, Morganti-Kossmann, M Cristina

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2008

Language:

english

File:

PDF, 209 KB

english, 2008

22

Interieukin-8 Released into the Cerebrospinal Fluid After Brain Injury Is Associated with Blood-Brain Barrier Dysfunction and Nerve Growth Factor Production

Kossmann, Thomas, Stahel, Philip F., Lenzlinger, Philipp M., Redl, Heinz, Dubs, Rolf W., Trentz, Otmar, Schlag, Guenter, Morganti-Kossmann, Maria C.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1997

Language:

english

File:

PDF, 506 KB

english, 1997

23

Experimental Axonal Injury Triggers Interleukin-6 mRNA, Protein Synthesis and Release Into Cerebrospinal Fluid

Hans, Volkmar H. J., Kossmann, Thomas, Lenzlinger, Philipp M., Probstmeier, Rainer, Imhof, Hans-Georg, Trentz, Otmar, Morganti-Kossmann, Maria C.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1999

Language:

english

File:

PDF, 2.59 MB

english, 1999

24

Elevated Intracranial IL-18 in Humans and Mice After Traumatic Brain Injury and Evidence of Neuroprotective Effects of IL-18???Binding Protein After Experimental Closed Head Injury

Yatsiv, Ido, Morganti-Kossmann, Maria C., Perez, Daniel, Dinarello, Charles A., Novick, Daniela, Rubinstein, Menachem, Otto, Viviane I., Rancan, Mario, Kossmann, Thomas, Redaelli, Claudio A., Trentz,

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2002

Language:

english

File:

PDF, 454 KB

english, 2002

25

Central Nervous System???Targeted Complement Inhibition Mediates Neuroprotection After Closed Head Injury in Transgenic Mice

Rancan, Mario, Morganti-Kossmann, Maria C., Barnum, Scott R., Saft, Silvia, Schmidt, Oliver I., Ertel, Wolfgang, Stahel, Philip F.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

26

The Chemokine Fractalkine in Patients With Severe Traumatic Brain Injury and a Mouse Model of Closed Head Injury

Rancan, Mario, Bye, Nicole, Otto, Vivianne I., Trentz, Otmar, Kossmann, Thomas, Frentzel, Stefan, Morganti-Kossmann, Maria Cristina

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2004

Language:

english

File:

PDF, 313 KB

english, 2004

27

Interleukin-6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth factor production in astrocytes

Thomas Kossmann, Volkmar Hans, Hans-Georg Imhof, Otmar Trentz, Maria Cristina Morganti-Kossmann

Journal:

Year:

1996

Language:

english

File:

PDF, 911 KB

english, 1996

28

Attenuated neurological deficit, cell death and lesion volume in Fas-mutant mice is associated with altered neuroinflammation following traumatic brain injury

Jenna M. Ziebell, Nicole Bye, Bridgette D. Semple, Thomas Kossmann, Maria Cristina Morganti-Kossmann

Journal:

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

29

Modulation of immune response by head injury

Maria Cristina Morganti-Kossmann, Laveniya Satgunaseelan, Nicole Bye, Thomas Kossmann

Journal:

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

30

Characterisation of the early molecular events of the cerebral inflammation response following acute traumatic brain injury in human brain tissue

T. Frugier, D. O’Reilly, M.C. Morganti-Kossmann, C. McLean

Journal:

Year:

2009

Language:

english

File:

PDF, 88 KB

english, 2009

31

Deficiency of monocyte chemoattractant protein-1 (MCP-1/CCL2) improves long-term outcome in mice following traumatic brain injury (TBI)

B. Semple, N. Bye, N. Malakooti, J. Ziebell, T. Kossmann, M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

32

From cell death to neurogenesis: The broad-spectrum function of brain inflammation after trauma

M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

33

Characterising endogenous neurogenesis following experimental focal traumatic brain injury

N. Bye, M. Tran, N. Malakooti, T. Woodcock, M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

34

Measurement of brain specific proteins in traumatic brain injury (TBI)—A role for outcome prediction?

L. Satgunaseelan, E.B. Yan, D. Agyapomaa, P. Nguyen, T. Kossmann, D.J. Cooper, S. Vallance, M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 114 KB

english, 2009

35

Post-traumatic hypoxia worsens neuropathological damage in an animal model of diffuse axonal injury

S.C. Hellewell, E.B. Yan, D. Agyapomaa, M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

36

Increase tryptophan metabolism after traumatic brain injury

E.B. Yan, D.W. Walker, D. Agyapomaa, G.J. Guillemin, M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

37

Fas mediates tissue damage and neurological recovery following focal traumatic brain injury

J. Ziebell, N. Bye, B. Semple, N. Malakooti, T. Kossmann, M.C. Morganti-Kossmann

Journal:

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

38

Characterising endogenous neurogenesis following experimental focal traumatic brain injury (TBI), and investigating the effect of treatment with minocycline

N. Bye, S.Y. Ng, C. Morganti-Kossmann

Journal:

Year:

2010

Language:

english

File:

PDF, 53 KB

english, 2010

39

Role of tissue type plasminogen activator in TBI

M. Sashindranath, J. Farrugia, E. Sales, D. Karadimos, S. Beckham, A. Galles, J. Rosenfeld, M.C. Morganti-Kossmann, R. Madani, J.D. Vassalli, R.L. Medcalf

Journal:

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

40

Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration but does not affect neurological recovery following closed head injury

B. Semple, N. Bye, J. Ziebell, M.C. Morganti-Kossmann

Journal:

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

41

MCP-1/CCL2 knockout mice exhibit improved neurological outcome, altered cytokine production, reduced macrophage infiltration and reduced lesion volume following focal traumatic brain injury

B. Semple, N. Bye, J. Ziebell, M.C. Morganti-Kossmann

Journal:

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

42

Treatment with minocycline, an anti-inflammatory drug, improves neurological outcome but does not affect neurogenesis following focal traumatic brain injury in mice

S.Y. Ng, N. Bye, M. Tran, B.D. Semple, T. Kossmann, M.C. Morganti-Kossmann

Journal:

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

43

Cytokine expression in post-mortem human brain tissue following acute traumatic brain injury

T. Frugier, D. O’Reilly, M.C. Morganti-Kossmann, C. McLean

Journal:

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

44

The role of monocyte chemoattractant protein-1 (MCP-1) in neurogenesis after traumatic brain injury (TBI)

M. Risteski, N. Bye, S.Y. Ng, B. Semple, M.C. Morganti-Kossmann

Journal:

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

45

Diffuse traumatic axonal injury induces sensorimotor deficit, memory loss and hippocampal axonal hyperexcitability

D.S. Alwis, H.A. Coleman, H.C. Parkington, A.M. Zhang, M.C. Morganti-Kossmann, E.B. Yan

Journal:

Year:

2010

Language:

english

File:

PDF, 265 KB

english, 2010

46

Post-trauma hypoxia exacerbates neurological deficits, neuroinflammation, and axonal damage in a rat model of diffuse axonal injury

E.B. Yan, S.C. Hellewell, D. Agyapomaa, M.C. Morganti-Kossmann

Journal:

Year:

2010

Language:

english

File:

PDF, 51 KB

english, 2010

47

Animal models of traumatic brain injury: Is there an optimal model to reproduce human brain injury in the laboratory?

M.C. Morganti-Kossmann, E. Yan, N. Bye

Journal:

Year:

2010

Language:

english

File:

PDF, 124 KB

english, 2010

48

Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury

Bridgette D. Semple, Nicole Bye, Jenna M. Ziebell, M. Cristina Morganti-Kossmann

Journal:

Neurobiology of Disease

Year:

2010

Language:

english

File:

PDF, 874 KB

english, 2010

49

Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-α following closed head injury in mice

Philip F Stahel, Karin Kariya, Esther Shohami, Scott R Barnum, Hans-Pietro Eugster, Otmar Trentz, Thomas Kossmann, Maria C Morganti-Kossmann

Journal:

Journal of Neuroimmunology

Year:

2000

Language:

english

File:

PDF, 1.19 MB

english, 2000

50

Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans

Philipp M Lenzlinger, Andreas Marx, Otmar Trentz, Thomas Kossmann, Maria-Cristina Morganti-Kossmann

Journal:

Journal of Neuroimmunology

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002