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51

Organization and evolution of structural elements within complex I

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1998

Language:

english

File:

PDF, 532 KB

english, 1998

52

Characterisation of the last Fe-S cluster-binding subunit of Neurospora crassa complex I

Rita Sousa, Blanca Barquera, Margarida Duarte, Moshe Finel, Arnaldo Videira

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1999

Language:

english

File:

PDF, 435 KB

english, 1999

53

The NADH oxidation domain of Complex I: do bacterial and mitochondrial enzymes catalyze ferricyanide reduction similarly?

Volker Zickermann, Sari Kurki, Marko Kervinen, Ilmo Hassinen, Moshe Finel

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2000

Language:

english

File:

PDF, 214 KB

english, 2000

54

Highly variable pH effects on the interaction of diclofenac and indomethacin with human UDP-glucuronosyltransferases

Hongbo Zhang, Anne Soikkeli, Ari Tolonen, Timo Rousu, Jouni Hirvonen, Moshe Finel

Journal:

Toxicology in Vitro

Year:

2012

Language:

english

File:

PDF, 661 KB

english, 2012

55

Phenylalanine 90 and 93 Are Localized within the Phenol Binding Site of Human UDP-Glucuronosyltransferase 1A10 as Determined by Photoaffinity Labeling, Mass Spectrometry, and Site-Directed Mutagenesis †

Xiong, Yan, Bernardi, Dan, Bratton, Stacie, Ward, Michael D., Battaglia, Eric, Finel, Moshe, Drake, Richard R., Radominska-Pandya, Anna

Journal:

Year:

2006

Language:

english

File:

PDF, 258 KB

english, 2006

56

Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17

Bichlmaier, Ingo, Siiskonen, Antti, Kurkela, Mika, Finel, Moshe, Yli-Kauhaluoma, Jari

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

57

Properties of the two terminal oxidases of Escherichia coli

Puustinen, Anne, Finel, Moshe, Haltia, Tuomas, Gennis, Robert B., Wikstrom, Marten

Journal:

Year:

1991

Language:

english

File:

PDF, 815 KB

english, 1991

58

Stereochemical Sensitivity of the Human UDP-glucuronosyltransferases 2B7 and 2B17

Bichlmaier, Ingo, Siiskonen, Antti, Finel, Moshe, Yli-Kauhaluoma, Jari

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 169 KB

english, 2006

59

Isoform-Selective Inhibition of the Human UDP-glucuronosyltransferase 2B7 by Isolongifolol Derivatives

Bichlmaier, Ingo, Kurkela, Mika, Joshi, Tanmaya, Siiskonen, Antti, Rüffer, Tobias, Lang, Heinrich, Suchanová, Bohumila, Vahermo, Mikko, Finel, Moshe, Yli-Kauhaluoma, Jari

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 162 KB

english, 2007

60

SVM Classification and CoMSIA Modeling of UGT1A6 Interacting Molecules

Ghemtio, Leo, Soikkeli, Anne, Yliperttula, Marjo, Hirvonen, Jouni, Finel, Moshe, Xhaard, Henri

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 6.62 MB

english, 2014

61

Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into two subcomplexes, one of which contains the redox centers of the enzyme

Finel, Moshe, Skehel, J. Mark, Albracht, Simon P. J., Fearnley, Ian M., Walker, John E.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.96 MB

english, 1992

62

Analysis of the Pathogenic Human Mitochondrial Mutation ND1/3460, and Mutations of Strictly Conserved Residues in Its Vicinity, Using the Bacterium Paracoccus d enitrificans †

Zickermann, Volker, Barquera, Blanca, Wikström, Mårten, Finel, Moshe

Journal:

Year:

1998

Language:

english

File:

PDF, 79 KB

english, 1998

63

Mutagenesis of Three Conserved Glu Residues in a Bacterial Homologue of the ND1 Subunit of Complex I Affects Ubiquinone Reduction Kinetics but Not Inhibition by Dicyclohexylcarbodiimide †

Kurki, Sari, Zickermann, Volker, Kervinen, Marko, Hassinen, Ilmo, Finel, Moshe

Journal:

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

64

A Pair of Membrane-Embedded Acidic Residues in the NuoK Subunit of Escherichia coli NDH-1, a Counterpart of the ND4L Subunit of the Mitochondrial Complex I, Are Required for High Ubiquinone Reductase Activity †

Kervinen, Marko, Pätsi, Jukka, Finel, Moshe, Hassinen, Ilmo E.

Journal:

Year:

2004

Language:

english

File:

PDF, 192 KB

english, 2004

65

A high throughput assay for the glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin by recombinant human UDP-glucuronosyltransferases and liver microsomes

Rahikainen, Tuomas, Häkkinen, Merja R., Finel, Moshe, Pasanen, Markku, Juvonen, Risto O.

Journal:

Year:

2013

Language:

english

File:

PDF, 1022 KB

english, 2013

66

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10

Gramec Skledar, Darja, Troberg, Johanna, Lavdas, Jason, Peterlin Mašič, Lucija, Finel, Moshe

Journal:

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

67

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues

Court, Michael H., Zhang, Xiuling, Ding, Xinxin, Yee, Karen K., Hesse, Leah M., Finel, Moshe

Journal:

Year:

2012

Language:

english

File:

PDF, 779 KB

english, 2012

68

Exploring the structure–activity relationships of ABCC2 modulators using a screening approach

Wissel, Gloria, Kudryavtsev, Pavel, Ghemtio, Leo, Tammela, Päivi, Wipf, Peter, Yliperttula, Marjo, Finel, Moshe, Urtti, Arto, Kidron, Heidi, Xhaard, Henri

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.27 MB

english, 2015

69

An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications

Lv, Xia, Ge, Guang-Bo, Feng, Lei, Troberg, Johanna, Hu, Liang-Hai, Hou, Jie, Cheng, Hai-Ling, Wang, Ping, Liu, Zhao-Ming, Finel, Moshe, Cui, Jing-Nan, Yang, Ling

Journal:

Biosensors and Bioelectronics

Year:

2015

Language:

english

File:

PDF, 935 KB

english, 2015

70

The UDP-Glucuronosyltransferases as Oligomeric Enzymes

Finel, Moshe, Kurkela, Mika

Journal:

Current Drug Metabolism

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

71

Purification and Characterization of a Glycerol-Resistant CF₀-CF₁ and CF₁-ATPase from the Halotolerant Alga Dunaliella bardawil

Moshe Finel, Uri Pick, Susanne Selman-Reimer and Bruce R. Selman

Journal:

PLANT PHYSIOLOGY

Year:

1984

File:

PDF, 1.27 MB

1984

72

Purification and Characterization of a Glycerol-Resistant CF₀-CF₁ and CF₁-ATPase from the Halotolerant Alga Dunaliella bardawil

Moshe Finel, Uri Pick, Susanne Selman-Reimer and Bruce R. Selman

Journal:

PLANT PHYSIOLOGY

Year:

1984

Language:

english

File:

PDF, 1.27 MB

english, 1984

73

Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms

Street, Christina M., Zhu, Zhaohui, Finel, Moshe, Court, Michael H.

Journal:

Year:

2016

Language:

english

File:

PDF, 679 KB

english, 2016

74

Influence of metabolism on endocrine activities of bisphenol S

Skledar, Darja Gramec, Schmidt, Jan, Fic, Anja, Klopčič, Ivana, Trontelj, Jurij, Dolenc, Marija Sollner, Finel, Moshe, Mašič, Lucija Peterlin

Journal:

Year:

2016

Language:

english

File:

PDF, 709 KB

english, 2016

75

Biosynthesis of Drug Glucuronide Metabolites in Budding Yeast Saccharomyces cerevisiae

Ikushiro, Shinichi, Nishikawa, Miyu, Masuyama, Yuuka, Shouji, Tadashi, Fujii, Miharu, Hamada, Masahiro, Nakajima, Noriyuki, Finel, Moshe, Yasuda, Kaori, Kamakura, Masaki, Sakaki, Toshiyuki

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

76

Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme

Pätsi, Jukka, Kervinen, Marko, Finel, Moshe, Hassinen, Ilmo E.

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

77

Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3

Sneitz, Nina, Court, Michael H., Zhang, Xiuling, Laajanen, Kaisa, Yee, Karen K., Dalton, Pamela, Ding, Xinxin, Finel, Moshe

Journal:

Pharmacogenetics and Genomics

Year:

2009

Language:

english

File:

PDF, 620 KB

english, 2009

78

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6

Kurkela, Mika, Patana, Anne-Sisko, Mackenzie, Peter I., Court, Michael H., Tate, Christopher G., Hirvonen, Jouni, Goldman, Adrian, Finel, Moshe

Journal:

Pharmacogenetics and Genomics

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

79

UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?

Troberg, Johanna, Järvinen, Erkka, Ge, Guang-Bo, Yang, Ling, Finel, Moshe

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 455 KB

english, 2016

80

Diphenyleneiodonium inhibits reduction of iron-sulfur clusters in the mitochondrial NADH-ubiquinone oxidoreductase (Complex I)

Majander, Anna, Finel, Moshe, Wikström, M\aa rten

Journal:

Journal of Biological Chemistry

Year:

1994

Language:

english

File:

PDF, 1.14 MB

english, 1994

81

Glucuronidation of clopidogrel by human UGT enzymes: Major contributions by UGT2B7 and UGT2B17

Kahma, Helinä, Filppula, Anne M., Neuvonen, Mikko, Tornio, Aleksi, Tarkiainen, E. Katriina, Holmberg, Mikko T., Itkonen, Matti K., Finel, Moshe, Neuvonen, Pertti J., Niemi, Mikko, Backman, Janne T.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

82

Identification and Characterization of Human UDP-glucuronosyltransferases Responsible for Xanthotoxol Glucuronidation

He, Guiyuan, Troberg, Johanna, Lv, Xia, Xia, Yang-Liu, Zhu, Liang-Liang, Ning, Jing, Ge, Guang-Bo, Finel, Moshe, Yang, Ling

Journal:

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

83

Selectivity in the efflux of glucuronides by human transporters MRP4 is highly active towards 4-methylumbelliferone and 1-naphthol glucuronides, while MRP3 exhibits stereoselective propranolol glucuronide transport

Järvinen, Erkka, Troberg, Johanna, Kidron, Heidi, Finel, Moshe

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.97 MB

english, 2017

84

Clopidogrel carboxylic acid glucuronidation is mediated mainly by UGT2B7, UGT2B4 and UGT2B17: Implications for pharmacogenetics and drug-drug interactions

Kahma, Helina, Filppula, Anne M., Neuvonen, Mikko, Tarkiainen, E. Katriina, Tornio, Aleksi, Holmberg, Mikko T., Itkonen, Matti K., Finel, Moshe, Neuvonen, Pertti J., Niemi, Mikko, Backman, Janne T.

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

85

EFFLUX TRANSPORT of ESTROGEN GLUCURONIDES by HUMAN MRP2, MRP3, MRP4 and BCRP

Järvinen, Erkka, Deng, Feng, Kidron, Heidi, Finel, Moshe

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2017

Language:

english

File:

PDF, 894 KB

english, 2017

86

Bisphenol AF: Does bisphenol AF glucuronide have endocrine activity?

Skledar, Darja Gramec, Carino, Adriana, Trontelj, Jurij, Finel, Moshe, Troberg, Johanna, Fiorucci, Stefano, Mašič, Lucija Peterlin

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

87

Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10

Juvonen, Risto O., Rauhamäki, Sanna, Kortet, Sami, Niinivehmas, Sanna, Troberg, Johanna, Petsalo, Aleksanteri, Huuskonen, Juhani, Raunio, Hannu, Finel, Moshe, Pentikäinen, Olli T.

Journal:

Molecular Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

88

Albumin Stimulates the Activity of the Human UDP-Glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the Effects Are Enzyme and Substrate Dependent

Manevski, Nenad, Troberg, Johanna, Svaluto-Moreolo, Paolo, Dziedzic, Klaudyna, Yli-Kauhaluoma, Jari, Finel, Moshe, Rodrigues-Lima, Fernando

Journal:

Year:

2013

Language:

english

File:

PDF, 719 KB

english, 2013

89

Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite

Skledar, Darja Gramec, Carino, Adriana, Trontelj, Jurij, Troberg, Johanna, Distrutti, Eleonora, Marchianò, Silvia, Tomašič, Tihomir, Zega, Anamarija, Finel, Moshe, Fiorucci, Stefano, Mašič, Lucija Pet

Journal:

Year:

2019

Language:

english

File:

PDF, 1.61 MB

english, 2019

90

A Novel Pathogenic UGT1A1 Variant in a Sudanese Child with Type I Crigler-Najjar Syndrome

Elfar, Walaa, Jarvinen, Erkka, Ji, Weizhen, Mosorin, Johanna, Sega, Annalisa G, Iuga, Alina C, Lobritto, Steven J, Konstantino, Monica, Chan, Albert, Finel, Moshe, Lakhani, Saquib A

Journal:

Drug Metabolism and Disposition

Year:

2018

Language:

english

File:

PDF, 1.69 MB

english, 2018

91

Recent progress and challenges in screening and characterization of UGT1A1 inhibitors

Lv, Xia, Xia, Yangliu, Finel, Moshe, Wu, Jingjing, Ge, Guangbo, Yang, Ling

Journal:

Acta Pharmaceutica Sinica B

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

92

Metabolism of Scoparone in Experimental Animals and Humans

Juvonen, Risto, Novák, Filip, Emmanouilidou, Eleni, Auriola, Seppo, Timonen, Juri, Heikkinen, Aki, Küblbeck, Jenni, Finel, Moshe, Raunio, Hannu

Journal:

Year:

2019

File:

PDF, 464 KB

2019

93

Metabolism of Scoparone in Experimental Animals and Humans

Juvonen, Risto, Novák, Filip, Emmanouilidou, Eleni, Auriola, Seppo, Timonen, Juri, Heikkinen, Aki, Küblbeck, Jenni, Finel, Moshe, Raunio, Hannu

Journal:

Year:

2019

Language:

english

File:

PDF, 464 KB

english, 2019

94

Characterization of human UGT2A3 expression using a prepared specific antibody against UGT2A3

Gotoh-Saito, Saki, Abe, Takayuki, Furukawa, Yoichi, Oda, Shingo, Yokoi, Tsuyoshi, Finel, Moshe, Hatakeyama, Masahiko, Fukami, Tatsuki, Nakajima, Miki

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2019

Language:

english

File:

PDF, 633 KB

english, 2019

95

Inhibition of human carboxylesterases by magnolol: Kinetic analyses and mechanism

Song, Yun-Qing, Weng, Zi-Miao, Dou, Tong-Yi, Finel, Moshe, Wang, Ya-Qiao, Ding, Le-Le, Jin, Qiang, Wang, Dan-Dan, Fang, Sheng-Quan, Cao, Yun-Feng, Hou, Jie, Ge, Guang-Bo

Journal:

Chemico-Biological Interactions

Year:

2019

Language:

english

File:

PDF, 3.39 MB

english, 2019

96

Efflux transport of nicotine, cotinine and trans ‐3′‐hydroxycotinine glucuronides by human hepatic transporters

Järvinen, Erkka, Sjöstedt, Noora, Koenderink, Jan B., Kidron, Heidi, Finel, Moshe

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2019

Language:

english

File:

PDF, 382 KB

english, 2019

97

In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs

Juvonen, Risto O., Heikkinen, Aki T., Kärkkäinen, Olli, Jehangir, Rabia, Huuskonen, Juhani, Troberg, Johanna, Raunio, Hannu, Pentikäinen, Olli T., Finel, Moshe

Journal:

European Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

98

Human Efflux Transport of Testosterone, Epitestosterone and Other Androgen Glucuronides

Järvinen, Erkka, Kidron, Heidi, Finel, Moshe

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2019

Language:

english

File:

PDF, 2.70 MB

english, 2019

99

An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

Zhu, Ya-Di, Pang, Hui-Lin, Zhou, Qi-Hang, Qin, Zi-Fei, Jin, Qiang, Finel, Moshe, Wang, Yi-Nan, QIN, Wei-Wei, Lu, Yin, Wang, Dan-Dan, Ge, Guang-Bo

Journal:

Journal of Pharmaceutical Analysis

Year:

2020

File:

PDF, 677 KB

2020