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1

Large Differences in Testosterone Excretion in Korean and Swedish Men Are Strongly Associated with a UDP-Glucuronosyl Transferase 2B17 Polymorphism

Jakobsson, Jenny, Ekström, Lena, Inotsume, Nobuo, Garle, Mats, Lorentzon, Mattias, Ohlsson, Claes, Roh, Hyung-Keun, Carlström, Kjell, Rane, Anders

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 210 KB

english, 2006

2

Effect of absorption rate on pharmacokinetics of ibuprofen in relation to chiral inversion in humans

Guohua Ding, Yang Liu, Jiewen Sun, Yuriko Takeuchi, Takaki Toda, Toru Hayakawa, Shoji Fukushima, Shuichi Kishimoto, Wenhui Lin, Nobuo Inotsume

Journal:

Journal of Pharmacy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 297 KB

english, 2007

3

The Inhibitory Effect of Telmisartan on the Metabolism of Arachidonic Acid by CYP2C9 and CYP2C8: An in Vitro Study

Kato, Yuka, Mukai, Yuji, Rane, Anders, Inotsume, Nobuo, Toda, Takaki

Year:

2017

Language:

english

File:

PDF, 840 KB

english, 2017

4

Disposition of enantiomers of sulpiride in humans and rats

Ayako Kamizono, Nobuo Inotsume, Shoji Fukushima, Masahiro Nakano, Yoshio Okamoto

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 322 KB

english, 1993

5

Direct chromatographic separation of 2-arylpropionic acid enantiomers using tris(3,5-dimethylphenylcarbamate)s of cellulose and amylose as chiral stationary phases

Yoshio Okamoto, Ryo Aburatani, Yuriko Kaida, Koichi Hatada, Nobuo Inotsume, Masahiro Nakano

Journal:

Year:

1989

Language:

english

File:

PDF, 299 KB

english, 1989

6

Reversible ring-opening reactions of nimetazepam and nitrazepam in acidic media at body temperature

Nobuo Inotsume, Masahiro Nakano

Journal:

Journal of Pharmaceutical Sciences

Year:

1980

Language:

english

File:

PDF, 465 KB

english, 1980

7

Inhibitory effects of procainamide and probenecid on renal excretion of sultopride enantiomers in rats

Ayako Kamizono, Nobuo Inotsume, Shoji Fukushima, Masahiro Nakano, Yoshio Okamoto

Journal:

Journal of Pharmaceutical Sciences

Year:

1993

Language:

english

File:

PDF, 318 KB

english, 1993

8

Determination of sultopride and tiapride in serum by gas chromatography using a surface ionisation detector

Ayako Kamizono, Nobuo Inotsume, Kenshiro Miyamoto, Keishi Ueda, Taihei Miyakawa, Hiromi Arimoto, Masahiro Nakano

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1991

Language:

english

File:

PDF, 239 KB

english, 1991

9

Rapid and sensitive determination of aprindine in serum by gas chromatography using a surface ionization detector

Hitomi Kawano, Nobuo Inotsume, Hiromi Arimoto, Toshihiro Fujii, Masahiro Nakano

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1989

Language:

english

File:

PDF, 408 KB

english, 1989

10

Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum

Nobuo Inotsume, Akimasa Higashi, Emiko Kinoshita, Tomoko Matsuoka, Masahiro Nakano

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1986

Language:

english

File:

PDF, 329 KB

english, 1986

11

Stereoselective analysis of the enantiomers of ethotoin in human serum using chiral stationary phase liquid chromatography and gas chromatography—mass spectrometry

Nobuo Inotsume, Junko Fujii, Mikiko Honda, Masahiro Nakano, Akimasa Higashi, Ichiro Matsuda

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1988

Language:

english

File:

PDF, 371 KB

english, 1988

12

Optical resolution of dihydropyridine enantiomers by high-performance liquid chromatography using phenylcarbamates of polysaccharides as a chiral stationary phase

Yoshio Okamoto, Ryo Aburatani, Koichi Hatada, Mikiko Honda, Nobuo Inotsume, Masahiro Nakano

Journal:

Journal of Chromatography A

Year:

1990

Language:

english

File:

PDF, 233 KB

english, 1990

13

Rapid determination of serum oxatomide levels with on-line precolumn solid-phase extraction

Junko Fujii, Nobuo Inotsume, Masahiro Nakano, Ikuro Matsukane, Akimasa Higashi, Ichiro Matsuda, Yoshihisa Sudo, Yasuyo Takahata

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 260 KB

english, 1990

14

Roles of Different CYP Enzymes in the Formation of Specific Fluvastatin Metabolites by Human Liver Microsomes

Takaki Toda, Erik Eliasson, Birgitta Ask, Nobuo Inotsume, Anders Rane

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2009

Language:

english

File:

PDF, 172 KB

english, 2009

15

Effects of absorption rate on the pre-systemic chiral inversion of ibuprofen in rabbits

Kosuke Doki, Toru Hayakawa, Wenhui Lin, Hitomi Yanaguimoto, Guohua Ding, Nobuo Inotsume

Journal:

Journal of Pharmacy and Pharmacology

Year:

2003

Language:

english

File:

PDF, 314 KB

english, 2003

16

Pharmacokinetic interaction of ibuprofen enantiomers in rabbits

Wenhui Lin, Toru Hayakawa, Hitomi Yanaguimoto, Mamoru Kuzuba, Takako Obara, Nobuo Inotsume, Wenhui Lin, Fude Cui, Guohua Ding

Journal:

Journal of Pharmacy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

17

Altered expression of MRP2, MRP3 and UGT2B1 in the liver affects the disposition of morphine and its glucuronide conjugate in a rat model of cholestasis

Yoshitaka Hasegawa, Shuichi Kishimoto, Hirokazu Takahashi, Nobuo Inotsume, Yoshikazu Takeuchi, Shoji Fukushima

Journal:

Journal of Pharmacy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 329 KB

english, 2009

18

The pharmacokinetics of morphine and its glucuronide conjugate in a rat model of streptozotocin-induced diabetes and the expression of MRP2, MRP3 and UGT2B1 in the liver

Yoshitaka Hasegawa, Shuichi Kishimoto, Naoki Shibatani, Hiromichi Nomura, Yuko Ishii, Mika Onishi, Nobuo Inotsume, Yoshikazu Takeuchi, Shoji Fukushima

Journal:

Journal of Pharmacy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 191 KB

english, 2010

19

Effects of insulin on CYP3A activity and nicardipine disposition in streptozotocin-induced diabetic rats

Yoshitaka Hasegawa, Shuichi Kishimoto, Naoki Shibatani, Nobuo Inotsume, Yoshikazu Takeuchi, Shoji Fukushima

Journal:

Journal of Pharmacy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

20

Stereoselective determination and pharmacokinetics of dihydropyridines: an updated review

Nobuo Inotsume, Masahiro Nakano

Journal:

Journal of Biochemical and Biophysical Methods

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

21

Effect of Activated Charcoal and Atropine on Absorption and/or Exsorption of Organophosphorus Compounds in Rats

AKI TOMIMARU, KAZUHIKO ARIMORI, NOBUO INOTSUME, MASAHIRO NAKANO

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 608 KB

english, 1996

22

Hydrolytic behavior of dantrolene in acidic media at body temperature

Inotsume, Nobuo, Nakano, Masahiro

Journal:

International Journal of Pharmaceutics

Year:

1983

Language:

english

File:

PDF, 214 KB

english, 1983

23

Reversible azomethine bond cleavage of nitrofurantoin in acidic solutions at body temperature

Nobuo, Inotsume, Masahirpo, Nakano

Journal:

International Journal of Pharmaceutics

Year:

1981

Language:

english

File:

PDF, 689 KB

english, 1981

24

Drug−drug Interaction between Losartan and Paclitaxel in Human Liver Microsomes with Different CYP2C8 Genotypes

Mukai, Yuji, Senda, Asuna, Toda, Takaki, Hayakawa, Toru, Eliasson, Erik, Rane, Anders, Inotsume, Nobuo

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2015

Language:

english

File:

PDF, 160 KB

english, 2015

25

Effect of Milk on Absorption of Norfloxacin in Healthy Volunteers

Minami, Rumiko, Inotsume, Nobuo, Nakano, Masahiro, Sudo, Yoshihisa, Higashi, Akimasa, Matsuda, Ichiro

Journal:

Journal of Clinical Pharmacology

Year:

1993

File:

PDF, 425 KB

1993

26

The Role of CYP2C8 and CYP2C9 Genotypes in Losartan-Dependent Inhibition of Paclitaxel Metabolism in Human Liver Microsomes

Mukai, Yuji, Senda, Asuna, Toda, Takaki, Eliasson, Erik, Rane, Anders, Inotsume, Nobuo

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2016

Language:

english

File:

PDF, 156 KB

english, 2016

27

Physiologic and Metabolic Aspects of Anticonvulsants

Matsuda, Ichiro, Higashi, Akimasa, Inotsume, Nobuo

Journal:

Pediatric Clinics of North America

Year:

1989

Language:

english

File:

PDF, 1.09 MB

english, 1989

28

Disposition of Enantiomers of Sultopride in a Human, Rats and Rabbits.

KAMIZONO, Ayako, INOTSUME, Nobuo, FUKUSHIMA, Syouji, NAKANO, Masahiro

Journal:

Biological & Pharmaceutical Bulletin

Year:

1993

File:

PDF, 508 KB

1993

29

Effect of Experimental Renal Failure on the Pharmacokinetics of Losartan in Rats

Yoshitani, Takashi, Yagi, Hitoshi, Inotsume, Nobuo, Yasuhara, Masato

Journal:

Biological & Pharmaceutical Bulletin

Year:

2002

Language:

english

File:

PDF, 88 KB

english, 2002

30

Altered Expression of Nuclear Receptors Affects the Expression of Metabolic Enzymes and Transporters in a Rat Model of Cholestasis

Hasegawa, Yoshitaka, Kishimoto, Shuichi, Takahashi, Hirokazu, Inotsume, Nobuo, Takeuchi, Yoshikazu, Fukushima, Shoji

Journal:

Biological & Pharmaceutical Bulletin

Year:

2009

Language:

english

File:

PDF, 812 KB

english, 2009

31

The Disposition of Pravastatin in a Rat Model of Streptozotocin-Induced Diabetes and Organic Anion Transporting Polypeptide 2 and Multidrug Resistance-Associated Protein 2 Expression in the Liver

Hasegawa, Yoshitaka, Kishimoto, Shuichi, Shibatani, Naoki, Inotsume, Nobuo, Takeuchi, Yoshikazu, Fukushima, Shoji

Journal:

Biological & Pharmaceutical Bulletin

Year:

2010

Language:

english

File:

PDF, 139 KB

english, 2010

32

Losartan Competitively Inhibits CYP2C8-Dependent Paclitaxel Metabolism in Vitro

Mukai, Yuji, Toda, Takaki, Hayakawa, Toru, Eliasson, Erik, Rane, Anders, Inotsume, Nobuo

Journal:

Biological & Pharmaceutical Bulletin

Year:

2014

Language:

english

File:

PDF, 530 KB

english, 2014

33

Simultaneous Determination Method of Epoxyeicosatrienoic Acids and Dihydroxyeicosatrienoic Acids by LC-MS/MS System

Mukai, Yuji, Toda, Takaki, Takeuchi, Satoya, Senda, Asuna, Yamashita, Miki, Eliasson, Erik, Rane, Anders, Inotsume, Nobuo

Year:

2015

Language:

english

File:

PDF, 642 KB

english, 2015

34

Effects of Angiotensin II Receptor Blockers on Metabolism of Arachidonic Acid via CYP2C8

Senda, Asuna, Mukai, Yuji, Toda, Takaki, Hayakawa, Toru, Yamashita, Miki, Eliasson, Erik, Rane, Anders, Inotsume, Nobuo

Year:

2015

Language:

english

File:

PDF, 727 KB

english, 2015

35

Relative bioavailability of midazolam following sublingual versus oral administration in healthy volunteers.

FUJII, Junko, INOTSUME, Nobuo, NAKANO, Masahiro

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 396 KB

1988

36

Reversible azomethine bond cleavage of guanabenz in acidic solutions at body temperature.

INOTSUME, NOBUO, NAKANO, MASAHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 443 KB

1988

37

Pharmacoeconomic Evaluation of Anti-Hyperlipidemic Agent Fenofibrate.

HAYAKAWA, Toru, SHIMOYAMA, Koichi, SEKIYA, Shigeru, SEKIGUCHI, Masatomo, INOTSUME, Nobuo

Journal:

YAKUGAKU ZASSHI

Year:

2002

Language:

english

File:

PDF, 210 KB

english, 2002

38

Comparison of Dexamethasone 8 mg and 16 mg for the Prevention of Acute and Delayed Cisplatin-induced Emesis in Patients with Lung Cancer

HAYAKAWA, Toru, SATO, Mayumi, HIROHATA, Tae, TOTSU, Sawako, MAKINO, Azusa, WADA, Yoshiko, SATO, Hideki, INOTSUME, Nobuo, FUJITA, Akihisa, SEKINE, Kyu-ichiro

Journal:

YAKUGAKU ZASSHI

Year:

2006

File:

PDF, 647 KB

2006

39

Establishment of Pharmaceutical Managements for Patient Care during Lung Cancer Chemotherapy and Its Quantitative Evaluation

HAYAKAWA, Toru, YAMANOUCHI, Kaori, HIROHATA, Tae, TOTSU, Sawako, MAKINO, Azusa, SATO, Hideki, FUJITA, Akihisa, SEKINE, Kyu-ichiro, INOTSUME, Nobuo

Journal:

YAKUGAKU ZASSHI

Year:

2005

File:

PDF, 331 KB

2005

40

Effect of food on the bioavailability of bromazepam following oral administration in healthy volunteers.

FUJII, Junko, INOTSUME, Nobuo, NAKANO, Masahiro

Journal:

Journal of Pharmacobio-Dynamics

Year:

1990

File:

PDF, 418 KB

1990

41

Preparation and evaluation of sustained release tablets prepared with .ALPHA.-starch.

NAKANO, MASAHIRO, NAKAZONO, NAOKO, INOTSUME, NOBUO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 488 KB

english, 1987

42

Degradation of bromazepam by the intestinal microflora.

FUJII, JUNKO, INOTSUME, NOBUO, NAKANO, MASAHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 687 KB

english, 1987

43

Studies on the Risk Factors for Fenofibrate-induced Elevation of Liver Function Tests.

HAYAKAWA, Toru, HAYASHI, Akemi, MIYAKAWA, Maiko, SHIMOYAMA, Koichi, SEKIYA, Shigeru, SEKIGUCHI, Masatomo, INOTSUME, Nobuo

Journal:

YAKUGAKU ZASSHI

Year:

2002

File:

PDF, 357 KB

2002

44

Plasma concentration profile of diazepam after oral administration of the open-ring form of diazepam to man.

Inotsume, Nobuo, Fujii, Junko, Nakano, Masahiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 387 KB

1986

45

Reversible ring-opening reactions of triazolobenzo- and triazolothienodiazepines in acidic media at around body temperature.

INOTSUME, NOBUO, NAKANO, MASAHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1980

File:

PDF, 624 KB

1980

46

Angiotensin II Receptor Blockers Inhibit the Generation of Epoxyeicosatrienoic Acid from Arachidonic Acid in Recombinant CYP2C9, CYP2J2 and Human Liver Microsomes

Senda, Asuna, Mukai, Yuji, Hayakawa, Toru, Kato, Yuka, Eliasson, Erik, Rane, Anders, Toda, Takaki, Inotsume, Nobuo

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2017

Language:

english

File:

PDF, 556 KB

english, 2017

47

Reply to ‘Multiple and Opposite Effects of Angiotensin II Receptor Blockers on the Bioavailability of Epoxyeicosatrienoic Acids’

Senda, Asuna, Mukai, Yuji, Hayakawa, Toru, Kato, Yuka, Eliasson, Erik, Rane, Anders, Toda, Takaki, Inotsume, Nobuo

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2017

Language:

english

File:

PDF, 44 KB

english, 2017

48

Combined effect of telmisartan and fluvastatin on arachidonic acid metabolism in human liver microsomes

Kato, Yuka, Mukai, Yuji, Rane, Anders, Inotsume, Nobuo, Toda, Takaki

Journal:

Year:

2017

Language:

english

File:

PDF, 959 KB

english, 2017

49

Reduction of Dantrolene by Enteric Bacteria

KUROIWA, MAKOTO, INOTSUME, NOBUO, IWAOKU, REIKO, NAKANO, MASAHIRO

Journal:

YAKUGAKU ZASSHI

Year:

1985

File:

PDF, 536 KB

1985

50

Reduction of Nitrazepam and Nimetazepam with Enteric Bacteria

KUROIWA, MAKOTO, INOTSUME, NOBUO, NAKANO, MASAHIRO

Journal:

YAKUGAKU ZASSHI

Year:

1986

Language:

english

File:

PDF, 745 KB

english, 1986