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101

Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells

Wang, Guang-hui, Mitsui, Kenichi, Kotliarova, Svetlana, Yamashita, Akira, Nagao, Yoshiro, Tokuhiro, Shinya, Iwatsubo, Takeshi, Kanazawa, Ichiro, Nukina, Nobuyuki

Journal:

Year:

1999

Language:

english

File:

PDF, 785 KB

english, 1999

102

Impaired degradation of PKC?? by proteasome in a cellular model of Huntington??s disease

Zemskov, Evgeny A., Nukina, Nobuyuki

Journal:

Year:

2003

Language:

english

File:

PDF, 129 KB

english, 2003

103

Rapamycin-induced oligomer formation system of FRB–FKBP fusion proteins

Inobe, Tomonao, Nukina, Nobuyuki

Journal:

Journal of Bioscience and Bioengineering

Year:

2016

Language:

english

File:

PDF, 2.01 MB

english, 2016

104

In situ detection of apolipoprotein E ε4 in archival human brain

Saito, Yuko, Ruberu, Nyoka N, Harada, Mieko, Arai, Tomio, Sawabe, Motoji, Nukina, Nobuyuki, Murayama, Shigeo

Journal:

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

105

Genome-wide analyses in neuronal cells reveal that upstream transcription factors regulate lysosomal gene expression

Yamanaka, Tomoyuki, Tosaki, Asako, Kurosawa, Masaru, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki

Journal:

Year:

2016

Language:

english

File:

PDF, 1.04 MB

english, 2016

106

Reappraisal of VAChT-Cre: Preference in Slow Motor Neurons Innervating Type I or IIa Muscle Fibers

Misawa, Hidemi, Inomata, Daijiro, Kikuchi, Miseri, Maruyama, Sae, Moriwaki, Yasuhiro, Okuda, Takashi, Nukina, Nobuyuki, Yamanaka, Tomoyuki

Journal:

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

107

Studies on sperm whale myoglobin mutants containing inserted glutamine repeats

Tanaka, Motomasa, Morishima, Isao, Nukina, Nobuyuki

Journal:

Biochemical Society Transactions

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

108

STUDIES ON CATECHOLAMINE BY HPLC WITH MULTI ECD

TAKAI, NOBUHARU, SHINOZUKA, NORIKO, MASHIGE, FUMIKO, OHKUBO, AKIYUKI, NUKINA, NOBUYUKI, IIJIMA, SETSU, FUKUI, YASUHIRO, SAKUMA, ICHIROU, ITOU, FUMIKO, MATSUSHIMA, YOSHIKAZU, NAGATA, YOSHIKO

Journal:

Analytical Sciences

Year:

1991

Language:

english

File:

PDF, 129 KB

english, 1991

109

Immunocytochemical study on senile plaques in Alzheimer's disease. II. Abnormal dendrites in senile plaques as revealed by antimicrotubule-associated proteins (MAPs) immunostaining.

NUKINA, Nobuyuki, IHARA, Yasuo

Journal:

Proceedings of the Japan Academy Series B Physical and Biological Sciences

Year:

1983

Language:

english

File:

PDF, 1.18 MB

english, 1983

110

Staining of Alzheimer's neurofibrillary tangles with antiserum against 200K component of neurofilament.

IHARA, Yasuo, NUKINA, Nobuyuki, SUGITA, Hideo, TOYOKURA, Yasuo

Journal:

Proceedings of the Japan Academy Series B Physical and Biological Sciences

Year:

1981

Language:

english

File:

PDF, 1.65 MB

english, 1981

111

Immunocytochemical study on senile plaques in Alzheimer's disease. I. Preparation of an antimicrotubule-associated proteins (MAPs) antiserum and its specificity.

NUKINA, Nobuyuki, IHARA, Yasuo

Journal:

Proceedings of the Japan Academy Series B Physical and Biological Sciences

Year:

1983

Language:

english

File:

PDF, 615 KB

english, 1983

112

Selective degradation of expanded polyglutamine proteins by their specific recognition with QBP1

Nagai, Yoshitaka, Nukina, Nobuyuki

Journal:

Rinsho Shinkeigaku

Year:

2011

File:

PDF, 185 KB

2011

113

Neurodegeration based on polyglutamine aggregation

Nukina, Nobuyuki

Journal:

Rinsho Shinkeigaku

Year:

2011

File:

PDF, 158 KB

2011

114

Pathomechanism of polyglutamine diseases and strategic design for their therapies

Nukina, Nobuyuki

Journal:

Rinsho Shinkeigaku

Year:

2008

File:

PDF, 163 KB

2008

115

FUS/TLS as a polyglutamine aggregate interacting protein

Nukina, Nobuyuki

Journal:

Rinsho Shinkeigaku

Year:

2010

File:

PDF, 203 KB

2010

116

Purification of polyglutamine aggregates and identification of elongation factor-1alpha and heat shock protein 84 as aggregate-interacting proteins.

Mitsui, Kenichi, Nakayama, Hiroshi, Akagi, Takumi, Nekooki, Munenori, Ohtawa, Kenji, Takio, Koji, Hashikawa, Tsutomu, Nukina, Nobuyuki

Journal:

The Journal of neuroscience : the official journal of the Society for Neuroscience

Year:

2002

Language:

english

File:

PDF, 748 KB

english, 2002

117

Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel β4 subunit explain its role in cell–cell adhesion

Shimizu, Hideaki, Tosaki, Asako, Ohsawa, Noboru, Ishizuka-Katsura, Yoshiko, Shoji, Shisako, Miyazaki, Haruko, Oyama, Fumitaka, Terada, Takaho, Shirouzu, Mikako, Sekine, Shun-ichi, Nukina, Nobuyuki, Yo

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 2.93 MB

english, 2017

118

1P018 Structures of binary complex of human BACE1 (β-secretase)(1. Protein structure and dynamics (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

Shimizu, Hideaki, Tosaki, Asako, Kaneko, Kumi, Sakurai, Takashi, Nukina, Nobuyuki

Journal:

Seibutsu Butsuri

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

119

1P-058 Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases(Protein:Property, The 47th Annual Meeting of the Biophysical Society of Japan)

Furukawa, Yoshiaki, Kaneko, Kumi, Kurosawa, Masaru, Matsumoto, Gen, Nukina, Nobuyuki

Journal:

Seibutsu Butsuri

Year:

2009

Language:

english

File:

PDF, 204 KB

english, 2009

120

2P048 1E1420 Structural polymorphism of protein aggregates and its pathological relevance(The 48th Annual Meeting of the Biophysical Society of Japan)

Furukawa, Yoshiaki, Kaneko, Kumi, Yamanaka, Koji, Nukina, Nobuyuki

Journal:

Seibutsu Butsuri

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

121

1P065 A new pathomechanism of amyotrophic lateral sclerosis regulated by aggregation of FUS/TLS protein(01C. Protein:Property,Poster)

Nomura, Takao, Watanabe, Shoji, Kaneko, Kumi, Yamanaka, Koji, Nukina, Nobuyuki, Furukawa, Yoshiaki

Journal:

Seibutsu Butsuri

Year:

2013

Language:

english

File:

PDF, 693 KB

english, 2013

122

2B1558 A mechanism controlling the morphologies of protein aggregates by "post-aggregation oxidation"(Proteins:Structure & Function II:Theory, Aggregation,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)

Mitomi, Yasushi, Nomura, Takao, Kurosawa, Masaru, Nukina, Nobuyuki, Furukawa, Yoshiaki

Journal:

Seibutsu Butsuri

Year:

2012

Language:

english

File:

PDF, 212 KB

english, 2012

123

3P059 Elimination of post-translational modifications in SOD1 leads to form pathological amyloid-like aggregates in familial ALS(Proteins-stability, folding, and other physicochemical properties,Oral Presentations)

Furukawa, Yoshiaki, Kaneko, Kumi, Yamanaka, Koji, Nukina, Nobuyuki

Journal:

Seibutsu Butsuri

Year:

2007

File:

PDF, 246 KB

2007

124

2P-076 Molecular dissection of SOD1 aggregation and its structural rationale(The 46th Annual Meeting of the Biophysical Society of Japan)

Furukawa, Yoshiaki, Kaneko, Kumi, Nukina, Nobuyuki

Journal:

Seibutsu Butsuri

Year:

2008

Language:

english

File:

PDF, 550 KB

english, 2008

125

Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains

Yamanaka, Tomoyuki, Tosaki, Asako, Kurosawa, Masaru, Akimoto, Kazunori, Hirose, Tomonori, Ohno, Shigeo, Hattori, Nobutaka, Nukina, Nobuyuki, Sacktor, Todd Charlton

Journal:

Year:

2013

Language:

english

File:

PDF, 13.61 MB

english, 2013

126

Large-Scale RNA Interference Screening in Mammalian Cells Identifies Novel Regulators of Mutant Huntingtin Aggregation

Yamanaka, Tomoyuki, Wong, Hon Kit, Tosaki, Asako, Bauer, Peter O., Wada, Koji, Kurosawa, Masaru, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki, Nagai, Yoshitaka

Journal:

Year:

2014

Language:

english

File:

PDF, 5.14 MB

english, 2014

127

1YP1-08 Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases(1YP1 Early Research in Biophysics Award Candidate Presentations,The 47th Annual Meeting of the Biophysical Society of Japan)

Furukawa, Yoshiaki, Kaneko, Kumi, Kurosawa, Masaru, Matsumoto, Gen, Nukina, Nobuyuki

Journal:

Seibutsu Butsuri

Year:

2009

Language:

english

File:

PDF, 198 KB

english, 2009

128

ER Dynamics and Derangement in Neurological Diseases

Yamanaka, Tomoyuki, Nukina, Nobuyuki

Journal:

Frontiers in Neuroscience

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

129

TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes

Takasugi, Nobumasa, Araya, Runa, Kamikubo, Yuji, Kaneshiro, Nanaka, Imaoka, Ryosuke, Jin, Hao, Kashiyama, Taku, Hashimoto, Yoshie, Kurosawa, Masaru, Uehara, Takashi, Nukina, Nobuyuki, Sakurai, Takashi

Journal:

Year:

2018

Language:

english

File:

PDF, 1.95 MB

english, 2018

130

Phosphorylated Tau Protein Is Integrated into Paired Helical Filaments in Alzheimer's Disease1

IHARA, Yasuo, NUKINA, Nobuyuki, MIURA, Reiko, OGAWARA, Midori

Journal:

Journal of Biochemistry

Year:

1986

Language:

english

File:

PDF, 1.58 MB

english, 1986

131

Non-coding RNA Neat1 and Abhd11os expressions are dysregulated in medium spiny neurons of Huntington disease model mice

Park, Hongsun, Miyazaki, Haruko, Yamanaka, Tomoyuki, Nukina, Nobuyuki

Journal:

Neuroscience Research

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

132

Biochemical and morphological classification of disease-associated alpha-synuclein mutants aggregates

Tanaka, Goki, Yamanaka, Tomoyuki, Furukawa, Yoshiaki, Kajimura, Naoko, Mitsuoka, Kaoru, Nukina, Nobuyuki

Journal:

Biochemical and Biophysical Research Communications

Year:

2018

Language:

english

File:

PDF, 947 KB

english, 2018

133

Sequence- and seed-structure-dependent polymorphic fibrils of alpha-synuclein

Tanaka, Goki, Yamanaka, Tomoyuki, Furukawa, Yoshiaki, Kajimura, Naoko, Mitsuoka, Kaoru, Nukina, Nobuyuki

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2019

Language:

english

File:

PDF, 15.02 MB

english, 2019

134

Preserved proteinase K-resistant core after amplification of alpha-synuclein aggregates: Implication to disease-related structural study

Yoshinaga, Saki, Yamanaka, Tomoyuki, Miyazaki, Haruko, Okuzumi, Ayami, Hiyama, Akiko, Murayama, Shigeo, Nukina, Nobuyuki

Journal:

Biochemical and Biophysical Research Communications

Year:

2019

File:

PDF, 1.49 MB

2019

135

Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation

Yamanaka, Tomoyuki, Nishiyama, Risa, Shimogori, Tomomi, Nukina, Nobuyuki

Journal:

Scientific Reports

Year:

2020

File:

PDF, 6.30 MB

2020

136

FACS array-based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model

Miyazaki, Haruko, Yamanaka, Tomoyuki, Oyama, Fumitaka, Kino, Yoshihiro, Kurosawa, Masaru, Yamada-Kurosawa, Mizuki, Yamano, Risa, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 2.11 MB

2020

137

Purification of Polyglutamine Aggregates and Identification of Elongation Factor-1Î± and Heat Shock Protein 84 as Aggregate-Interacting Proteins

Mitsui, Kenichi, Nakayama, Hiroshi, Akagi, Takumi, Nekooki, Munenori, Ohtawa, Kenji, Takio, Koji, Hashikawa, Tsutomu, Nukina, Nobuyuki

Journal:

Journal of Neuroscience

Year:

2002

File:

PDF, 748 KB

2002

138

CELF2 regulates the species-specific alternative splicing of TREM2

Yanaizu, Motoaki, Washizu, Chika, Nukina, Nobuyuki, Satoh, Jun-ichi, Kino, Yoshihiro

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.41 MB

2020

139

Gene expression profiling in neuronal cells identifies a different type of transcriptome modulated by NF-Y

Yamanaka, Tomoyuki, Miyazaki, Haruko, Tosaki, Asako, Maity, Sankar N., Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki

Journal:

Scientific Reports

Year:

2020

File:

PDF, 7.10 MB

2020