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1

Pancreatic Adenocarcinoma

Ryan, David P., Hong, Theodore S., Bardeesy, Nabeel

Journal:

New England Journal of Medicine

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

2

10.1038/22788

Chin, Lynda, DePinho#, Ronald A., Tam, Alice, Pomerantz, Jason, Wong, Michelle, Holash, Jocelyn, Bardeesy, Nabeel, Shen, Qiong, O'Hagan, Ronan, Pantginis, Joe, Zhou, Hao, Horner, James W., Cordon-Card

Journal:

Year:

1999

Language:

english

File:

PDF, 472 KB

english, 1999

3

Pancreatic cancer biology and genetics

Bardeesy, Nabeel, DePinho, Ronald A.

Journal:

Nature Reviews Cancer

Year:

2002

Language:

english

File:

PDF, 2.56 MB

english, 2002

4

Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model

Burd, Christin E., Sorrentino, Jessica A., Clark, Kelly S., Darr, David B., Krishnamurthy, Janakiraman, Deal, Allison M., Bardeesy, Nabeel, Castrillon, Diego H., Beach, David H., Sharpless, Norman E.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.64 MB

english, 2013

5

TGF-β Tumor Suppression through a Lethal EMT

David, Charles J., Huang, Yun-Han, Chen, Mo, Su, Jie, Zou, Yilong, Bardeesy, Nabeel, Iacobuzio-Donahue, Christine A., Massagué, Joan

Journal:

Year:

2016

Language:

english

File:

PDF, 6.92 MB

english, 2016

6

Reprogramming Enhancers to Drive Metastasis

Mostoslavsky, Raul, Bardeesy, Nabeel

Journal:

Year:

2017

Language:

english

File:

PDF, 401 KB

english, 2017

7

Noncoordinate developmental regulation of N-cadherin, N-CAM, integrin, and fibronectin mRNA levels during myoblast terminal differentiation

Colin D. MacCalman, Nabeel Bardeesy, Paul C. Holland, Orest W. Blaschuk

Journal:

Developmental Dynamics

Year:

1992

Language:

english

File:

PDF, 856 KB

english, 1992

8

Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma

Vikram Deshpande, Afamefuna Nduaguba, Stephanie M Zimmerman, Sarah M Kehoe, Laura E MacConaill, Gregory Y Lauwers, Cristina Ferrone, Nabeel Bardeesy, Andrew X Zhu, Aram F Hezel

Journal:

Year:

2011

Language:

english

File:

PDF, 929 KB

english, 2011

9

10.1038/35092592

Sharpless, Norman E., Bardeesy, Nabeel, Lee, Kee-Ho, Carrasco, Daniel, Castrillon, Diego H., Aguirre, Andrew J., Wu, Emily A., Horner, James W., DePinho, Ronald A.

Journal:

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

10

10.1038/35092604

Sharpless, Norman E., Bardeesy, Nabeel, Lee, Kee-Ho, Carrasco, Daniel, Castrillon, Diego H., Aguirre, Andrew J., Wu, Emily A., Horner, James W., DePinho, Ronald A.

Journal:

Year:

2001

Language:

english

File:

PDF, 145 KB

english, 2001

11

10.1038/35092600

Sharpless, Norman E., Bardeesy, Nabeel, Lee, Kee-Ho, Carrasco, Daniel, Castrillon, Diego H., Aguirre, Andrew J., Wu, Emily A., Horner, James W., DePinho, Ronald A.

Journal:

Year:

2001

Language:

english

File:

PDF, 178 KB

english, 2001

12

10.1038/35092609

Sharpless, Norman E., Bardeesy, Nabeel, Lee, Kee-Ho, Carrasco, Daniel, Castrillon, Diego H., Aguirre, Andrew J., Wu, Emily A., Horner, James W., DePinho, Ronald A.

Journal:

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

13

Uncapping NF-κB activity in pancreatic cancer

Gurumurthy, Sushma, Bardeesy, Nabeel

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

14

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

Bardeesy, Nabeel, Sinha, Manisha, Hezel, Aram F., Signoretti, Sabina, Hathaway, Nathaniel A., Sharpless, Norman E., Loda, Massimo, Carrasco, Daniel R., DePinho, Ronald A.

Journal:

Year:

2002

Language:

english

File:

PDF, 586 KB

english, 2002

15

LKB1 (XEEK1) regulates Wnt signalling in vertebrate development

Ossipova, Olga, Bardeesy, Nabeel, DePinho, Ronald A., Green, Jeremy B. A.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 757 KB

english, 2003

16

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

Katajisto, Pekka, Vaahtomeri, Kari, Ekman, Niklas, Ventelä, Eeva, Ristimäki, Ari, Bardeesy, Nabeel, Feil, Robert, DePinho, Ronald A, Mäkelä, Tomi P

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 830 KB

english, 2008

17

Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development

Bruening, Wendy, Bardeesy, Nabeel, Silverman, Bernard L., Cohn, Richard A., Machin, Geoffrey A., Aronson, Andrew J., Housman, David, Pelletier, Jerry

Journal:

Nature Genetics

Year:

1992

File:

PDF, 521 KB

1992

18

Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations

Bardeesy, Nabeel, Falkoff, David, Petruzzi, Mary-Jane, Nowak, Norma, Zabel, Bernhard, Adam, Mohammed, Aguiar, Maria C., Grundy, Paul, Shows, Tom, Pelletier, Jerry

Journal:

Nature Genetics

Year:

1994

File:

PDF, 783 KB

1994

19

Amplification-free digital gene expression profiling from minute cell quantities

Ozsolak, Fatih, Ting, David T, Wittner, Ben S, Brannigan, Brian W, Paul, Suchismita, Bardeesy, Nabeel, Ramaswamy, Sridhar, Milos, Patrice M, Haber, Daniel A

Journal:

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

20

LKB1-AMPK axis revisited

Kottakis, Filippos, Bardeesy, Nabeel

Journal:

Year:

2012

Language:

english

File:

PDF, 455 KB

english, 2012

21

The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model

Nabeel Bardeesy, Norman E. Sharpless, Ronald A. DePinho, Glenn Merlino

Journal:

Seminars in Cancer Biology

Year:

2001

Language:

english

File:

PDF, 3.06 MB

english, 2001

22

The LKB1 tumor suppressor negatively regulates mTOR signaling

Reuben J Shaw, Nabeel Bardeesy, Brendan D Manning, Lyle Lopez, Monica Kosmatka, Ronald A DePinho, Lewis C Cantley

Journal:

Year:

2004

Language:

english

File:

PDF, 376 KB

english, 2004

23

Pten constrains centroacinar cell expansion and malignant transformation in the pancreas

Ben Z. Stanger, Bangyan Stiles, Gregory Y. Lauwers, Nabeel Bardeesy, Michael Mendoza, Ying Wang, Amy Greenwood, Kuang-hung Cheng, Margaret McLaughlin, Dennis Brown, Ronald A. DePinho, Hong Wu, Douglas

Journal:

Year:

2005

Language:

english

File:

PDF, 814 KB

english, 2005

24

RAS unplugged: Negative feedback and oncogene-induced senescence

Nabeel Bardeesy, Norman E. Sharpless

Journal:

Year:

2006

Language:

english

File:

PDF, 269 KB

english, 2006

25

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

Dawang Zhou, Claudius Conrad, Fan Xia, Ji-Sun Park, Bernhard Payer, Yi Yin, Gregory Y. Lauwers, Wolfgang Thasler, Jeannie T. Lee, Joseph Avruch, Nabeel Bardeesy

Journal:

Year:

2009

Language:

english

File:

PDF, 1.73 MB

english, 2009

26

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

Anurag Singh, Patricia Greninger, Daniel Rhodes, Louise Koopman, Sheila Violette, Nabeel Bardeesy, Jeff Settleman

Journal:

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

27

Mst1 and Mst2 control liver size and suppress the development of hepatocellular carcinoma

Claudius Conrad, Dawang Zhou, Ji Sun Park, Joseph Avruch, Andrew Warshaw, Nabeel Bardeesy

Journal:

Journal of the American College of Surgeons

Year:

2009

Language:

english

File:

PDF, 93 KB

english, 2009

28

Characterization of a Region-Specific Library of Microclones in the Vicinity of the Bcg and splotch Loci on Mouse Chromosome 1

Douglas J. Epstein, Nabeel Bardeesy, Silvia Vidal, Danielle Malo, Andreas Weith, Michel Vekemans, Philippe Gros

Journal:

Year:

1994

File:

PDF, 205 KB

1994

29

WT1 Mutations Associated with Incomplete Denys-Drash Syndrome Define a Domain Predicted to Behave in a Dominant-Negative Fashion

Nabeel Bardeesy, Bernhard Zabel, Klaus Schmitt, Jerry Pelletier

Journal:

Year:

1994

File:

PDF, 173 KB

1994

30

Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway

Motoharu Awazawa, Kohjiro Ueki, Kazunori Inabe, Toshimasa Yamauchi, Kazuma Kaneko, Yukiko Okazaki, Nabeel Bardeesy, Shin Ohnishi, Ryozo Nagai, Takashi Kadowaki

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 320 KB

english, 2009

31

Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGFβ type II receptor independent manner

Yingqi Teng, Keizo Kanasaki, Nabeel Bardeesy, Hikaru Sugimoto, Raghu Kalluri

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 1.93 MB

english, 2011

32

Loss of Lkb1 in Adult β Cells Increases β Cell Mass and Enhances Glucose Tolerance in Mice

Accalia Fu, Andy Cheuk-Him Ng, Chantal Depatie, Nadeeja Wijesekara, Ying He, Gen-Sheng Wang, Nabeel Bardeesy, Fraser W. Scott, Rhian M. Touyz, Michael B. Wheeler, Robert A. Screaton

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 1.25 MB

english, 2009

33

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E. Kemp, Nabeel Bardeesy, Patrick Dennis, John J. Schlager, André Marette, Sara C. Kozma, George Thomas

Journal:

Cell Metabolism

Year:

2010

Language:

english

File:

PDF, 1.32 MB

english, 2010

34

Ink4a/Arf Regulation by let-7b and Hmga2: A Genetic Pathway Governing Stem Cell Aging

Alexandros Tzatsos, Nabeel Bardeesy

Journal:

Year:

2008

Language:

english

File:

PDF, 127 KB

english, 2008

35

Ready, Set, Go: The EGF Receptor at the Pancreatic Cancer Starting Line

Rushika M. Perera, Nabeel Bardeesy

Journal:

Year:

2012

Language:

english

File:

PDF, 152 KB

english, 2012

36

Tumorigenesis: Modeling Kras in cells and mice

Sushma Gurumurthy, Nabeel Bardeesy

Journal:

Drug Discovery Today: Disease Models

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

37

Protein kinases of the Hippo pathway: Regulation and substrates

Avruch, Joseph, Zhou, Dawang, Fitamant, Julien, Bardeesy, Nabeel, Mou, Fan, Barrufet, Laura Regué

Journal:

Seminars in Cell & Developmental Biology

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

38

852 The Tumor Vasculature is a Paracrine Target of Hedgehog in Pancreatic Cancer

Yoshiaki Sugiyama, Yusuke Mizukami, Junpei Sasajima, Kazumasa Nakamura, Toru Kawamoto, Kazuya Koizumi, Mikihiro Fujiya, Satoshi Tanno, Hidenori Karasaki, Toru Kono, Daniel C. Chung, Nabeel Bardeesy, Y

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

39

The Paracrine Effect of Hedgehog on Bone Marrow-Derived Stromal Cells Occurs at Later Stages of Pancreatic Tumorigenesis

Yoshiaki Sugiyama, Yusuke Mizukami, Toru Kawamoto, Junpei Sasajima, Kazuya Koizumi, Yoshiki Nomura, Kentaro Moriichi, Mikihiro Fujiya, Nabeel Bardeesy, Daniel C. Chung, Yutaka Kohgo

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

40

LKB1 suppresses melanoma metastasis: the answer is YES

Kottakis, Filippos, Gurumurthy, Sushma, Bardeesy, Nabeel

Journal:

Pigment Cell & Melanoma Research

Year:

2012

Language:

english

File:

PDF, 43 KB

english, 2012

41

Cancer: When antioxidants are bad

Perera, Rushika M., Bardeesy, Nabeel

Journal:

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

42

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

Tumaneng, Karen, Schlegelmilch, Karin, Russell, Ryan C., Yimlamai, Dean, Basnet, Harihar, Mahadevan, Navin, Fitamant, Julien, Bardeesy, Nabeel, Camargo, Fernando D., Guan, Kun-Liang

Journal:

Nature Cell Biology

Year:

2012

Language:

english

File:

PDF, 2.83 MB

english, 2012

43

[Advances in Cancer Research] Volume 79 || Animal models of melanoma: Recent advances and future prospects

Bardeesy, Nabeel

Year:

2000

Language:

english

File:

PDF, 3.83 MB

english, 2000

44

Erratum: Role of the SIK2–p35–PJA2 complex in pancreatic β-cell functional compensation

Sakamaki, Jun-Ichi, Fu, Accalia, Reeks, Courtney, Baird, Stephen, Depatie, Chantal, Azzabi, Mufida Al, Bardeesy, Nabeel, Gingras, Anne-Claude, Yee, Siu-Pok, Screaton, Robert A.

Journal:

Nature Cell Biology

Year:

2014

Language:

english

File:

PDF, 553 KB

english, 2014

45

LKB1 contributes to the maintenance of glucose homeostasis in vivo.

Accalia, F.U., Andy Cheuk-Him, N.G., Depatie, Chantal, Wijesekara, Nadeeja, Wheeler, Michael B., Bardeesy, Nabeel, Screaton, Robert A.

Journal:

Canadian Journal of Diabetes

Year:

2008

Language:

english

File:

PDF, 700 KB

english, 2008

46

DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer

Bailey, Jennifer M., Alsina, Janivette, Rasheed, Zeshaan A., McAllister, Florencia M., Fu, Ya–Yuan, Plentz, Ruben, Zhang, Hao, Pasricha, Pankaj J., Bardeesy, Nabeel, Matsui, William, Maitra, Anirban,

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 4.40 MB

english, 2014

47

Targeting Cathepsin E in Pancreatic Cancer by a Small Molecule Allows In Vivo Detection

Keliher, Edmund J., Reiner, Thomas, Earley, Sarah, Klubnick, Jenna, Tassa, Carlos, Lee, Andrew J., Ramaswamy, Sridhar, Bardeesy, Nabeel, Hanahan, Douglas, DePinho, Ronald A., Castro, Cesar M., Weissle

Journal:

Year:

2013

Language:

english

File:

PDF, 2.75 MB

english, 2013

48

In Vivo Quantitative Microvasculature Phenotype Imaging of Healthy and Malignant Tissues Using a Fiber-Optic Confocal Laser Microprobe

Lin, Ken Young, Maricevich,, Marco, Bardeesy, Nabeel, Weissleder, Ralph, Mahmood, Umar

Journal:

Translational Oncology

Year:

2008

Language:

english

File:

PDF, 1.52 MB

english, 2008

49

It's true: all the best men are taken

Gao, Tao, Zhou, Dawang, Yang, Chenghua, Singh, Tarjinder, Penzo–Méndez, Alfredo, Maddipati, Ravikanth, Tzatsos, Alexandros, Bardeesy, Nabeel, Avruch, Joseph, Stanger, Ben Z.

Journal:

Year:

2009

Language:

english

File:

PDF, 126 KB

english, 2009

50

Notes, Short Comments, and Answersto Correspondents.

Gao, Tao, Zhou, Dawang, Yang, Chenghua, Singh, Tarjinder, Penzo–Méndez, Alfredo, Maddipati, Ravikanth, Tzatsos, Alexandros, Bardeesy, Nabeel, Avruch, Joseph, Stanger, Ben Z.

Journal:

Year:

1878

Language:

english

File:

PDF, 878 KB

english, 1878