Nabil SEIDAH: search on Z-Library

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1

Loss-of-function PCSK9 mutants evade the unfolded protein response sensor, GRP78, and fail to induce endoplasmic reticulum stress when retained

Lebeau, Paul, Platko, Khrystyna, Al-Hashimi, Ali A, Byun, Jae Hyun, Lhoták, Šárka, Holzapfel, Nicholas, Gyulay, Gabriel, Igdoura, Suleiman A., Cool, David, Trigatti, Bernardo, Seidah, Nabil G., Austin

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 3.36 MB

english, 2018

2

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

Nabil G Seidah, Michel Chrétien*,

Journal:

Year:

1999

Language:

english

File:

PDF, 1.70 MB

english, 1999

3

The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit-1/GHF-1-independent pathway in corticotroph AtT20 cells

Stephen E Girardin, Suzanne Benjannet, Jean-Christophe Barale, Michel Chrétien, Nabil G Seidah

Journal:

Year:

1998

Language:

english

File:

PDF, 220 KB

english, 1998

4

The ever-expanding saga of the proprotein convertases and their roles in body homeostasis

Seidah, Nabil G., Chrétien, Michel, Mbikay, Majambu

Journal:

Current Opinion in Lipidology

Year:

2018

Language:

english

File:

PDF, 305 KB

english, 2018

5

Molecular cloning, characterization of cDNA, and distribution of mRNA encoding the frog prohormone convertase PC1

Gangnon, Fran�oise, Danger, Jean-Michel, Jegou, Sylvie, Vieau, Didier, Seidah, Nabil G., Vaudry, Hubert

Journal:

The Journal of Comparative Neurology

Year:

1999

Language:

english

File:

PDF, 952 KB

english, 1999

6

Proprotein convertase subtilisin/kexin type 9 (PCSK9): Hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

Ahmed Zaid, Anna Roubtsova, Rachid Essalmani, Jadwiga Marcinkiewicz, Ann Chamberland, Josée Hamelin, Michel Tremblay, Hélène Jacques, Weijun Jin, Jean Davignon, Nabil G. Seidah, Annik Prat

Journal:

Year:

2008

Language:

english

File:

PDF, 3.19 MB

english, 2008

7

Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases

Siegfried, Geraldine, Basak, Ajoy, Prichett-Pejic, Wendy, Scamuffa, Nathalie, Ma, Liming, Benjannet, Suzanne, Veinot, John P, Calvo, Fabien, Seidah, Nabil, Khatib, Abdel-Majid

Journal:

Year:

2005

Language:

english

File:

PDF, 545 KB

english, 2005

8

What lies ahead for the proprotein convertases?

Nabil G. Seidah

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 398 KB

english, 2011

9

The biology and therapeutic targeting of the proprotein convertases

Seidah, Nabil G., Prat, Annik

Journal:

Nature Reviews Drug Discovery

Year:

2012

Language:

english

File:

PDF, 641 KB

english, 2012

10

Arenavirus envelope glycoproteins mimic autoprocessing sites of the cellular proprotein convertase subtilisin kexin isozyme-1/site-1 protease

Antonella Pasquato, Dominique J. Burri, Esther Gomez-Ibarlucea Traba, Layane Hanna-El-Daher, Nabil G. Seidah, Stefan Kunz

Journal:

Year:

2011

Language:

english

File:

PDF, 487 KB

english, 2011

11

Implication of proprotein convertases in the processing and spread of severe acute respiratory syndrome coronavirus

Eric Bergeron, Martin J. Vincent, Louise Wickham, Josée Hamelin, Ajoy Basak, Stuart T. Nichol, Michel Chrétien, Nabil G. Seidah

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 987 KB

english, 2005

12

Dual regulation of the LDL receptor—Some clarity and new questions

Alan D. Attie, Nabil G. Seidah

Journal:

Cell Metabolism

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

13

Proprotein convertase subtilisin / kexin 9 (PCSK9) inhibitors and the future of dyslipidemia therapy: an updated patent review (2011-2015)

Elbitar, Sandy, Khoury, Petra El, Ghaleb, Youmna, Rabès, Jean-Pierre, Varret, Mathilde, Seidah, Nabil G., Boileau, Catherine, Abifadel, Marianne

Journal:

Expert Opinion on Therapeutic Patents

Year:

2016

Language:

english

File:

PDF, 822 KB

english, 2016

14

CORTICOTROP IN RELEASING FACTOR (CRF): EFFECTS ON THE RELEASE UF PRO-OPIOMELANOCORTIN (POMC)-RELATED PEHTIDES BY HUMAN ANTERIOR PITUITARY CELLS IN VITRO

CHAN, JOHN S.D., LU, CHAO-LIN, SEIDAH, NABIL G., CHRETIEN, MICHEL

Journal:

Year:

1982

Language:

english

File:

PDF, 373 KB

english, 1982

15

Molecular evolution of the proopiomelanocortin system in Barn owl species

LÃ¶w, Karin, Ducrest, Anne-Lyse, San-Jose, Luis M., Simon, CÃ©line, Uva, Vera, Seidah, Nabil G., Pasquato, Antonella, Kunz, Stefan, Roulin, Alexandre, Vaudry, Hubert

Journal:

Year:

2020

File:

PDF, 5.04 MB

2020

16

Pro-protein convertase gene expression in human breast cancer

Min Cheng, Peter Watson, Jean Paterson, Nabil Seidah, Michel Chrétien, Robert P.C. Shiu

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 169 KB

english, 1997

17

Immunohistochemical evidence for the involvement of protein convertases 5A and 2 in the processing of pro-neurotensin in rat brain

Pierre Villeneuve, Louise Lafortune, Nabil G. Seidah, Patrick Kitabgi, Alain Beaudet

Journal:

The Journal of Comparative Neurology

Year:

2000

Language:

english

File:

PDF, 1.48 MB

english, 2000

18

Regional and cellular localization of the neuroendocrine prohormone convertases PC1 and PC2 in the rat central nervous system

Raphaèlle Winsky-Sommerer, Suzanne Benjannet, Carole Rovère, Pierre Barbero, Nabil G. Seidah, Jacques Epelbaum, Pascal Dournaud

Journal:

The Journal of Comparative Neurology

Year:

2000

Language:

english

File:

PDF, 2.41 MB

english, 2000

19

5-Thiomannosides Block the Biosynthesis of Dolichol-Linked Oligosaccharides and Mimic Class I Congenital Disorders of Glycosylation

Dr. Wesley F. Zandberg, Dr. Ningguo Gao, Dr. Jayakanthan Kumarasamy, Dr. Mark A. Lehrman, Dr. Nabil G. Seidah, Dr. B. Mario Pinto

Journal:

Year:

2012

Language:

english

File:

PDF, 1.52 MB

english, 2012

20

A Highly Selective Cell Permeable Peptide Inhibitor of Proprotein Convertase 1: Design, Synthesis and Biological Evaluation in Cellular PC1 Mediated Proteolysis

Ajoy Basak, Peter Koch, Marcel Dupelle, Francine Sirois, Michel Chretien, Nabil G. Seidah, Majambu Mbikay

Journal:

Year:

2003

File:

PDF, 61 KB

2003

21

Molecular cloning and embryonic expression of zebrafish PCSK5 co-orthologues: Functional assessment during lateral line development

Babykumari P. Chitramuthu, David C. Baranowski, Benoît Cadieux, Estelle Rousselet, Nabil G. Seidah, Hugh P.J. Bennett

Journal:

Developmental Dynamics

Year:

2010

Language:

english

File:

PDF, 3.63 MB

english, 2010

22

Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells

Jodie P. Goodridge, Louise J. Lathbury, Noriko K. Steiner, Christine N. Shulse, Philomena Pullikotil, Nabil G. Seidah, Carolyn K. Hurley, Frank T. Christiansen, Campbell S. Witt

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 410 KB

english, 2007

23

PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression

Patrick Labonté, Syntia Begley, Carl Guévin, Marie-Claude Asselin, Nasha Nassoury, Gaétan Mayer, Annik Prat, Nabil G. Seidah

Journal:

Year:

2009

Language:

english

File:

PDF, 2.67 MB

english, 2009

24

Synthesis of the segment (11–23) located in the first tandem repeat of plasma kallikrein: comparative binding studies of this and another segment (328–343) to high-molecular-mass kininogen

Ajoy Basak, Xue Wen Yuan, Robert Harris, Nabil G. Seidah, Michel Chrétien

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 1.09 MB

english, 1993

25

Novel approach to rapid and sensitive localization of protein disulfide bridges by high-performance liquid chromatography and electrochemical detection

Claude Lazure, Jim Rochemont, Nabil G. Seidah, Michel Chrétien

Journal:

Journal of Chromatography A

Year:

1985

Language:

english

File:

PDF, 691 KB

english, 1985

26

Enzymatic maturation of pro-opiomelanocortin by anterior pituitary granules : Methodological approach leading to definite characterization of cleavage sites by means of high-performance liquid chromatography and microsequencing

Nabil G. Seidah, Didier Pélaprat, Jim Rochemont, Pierre Lambelin, Michael Dennis, John S.D. Chan, Josée Hamelin, Claude Lazure, Michel Chrétien

Journal:

Journal of Chromatography A

Year:

1983

Language:

english

File:

PDF, 900 KB

english, 1983

27

Characterization of β-endorphin immunoreactive peptides in rat pituitary and brain by coupled gel and reversed-phase high-performance liquid chromatography

Michael Dennis, Claude Lazure, Nabil G. Seidah, Michel Chrétien

Journal:

Journal of Chromatography A

Year:

1983

Language:

english

File:

PDF, 773 KB

english, 1983

28

Eukaryotic protein processing: endoproteolysis of precursor proteins

Nabil G Seidah, Michel Chrétien

Journal:

Current Opinion in Biotechnology

Year:

1997

Language:

english

File:

PDF, 769 KB

english, 1997

29

Inhibition of HIV-2ROD replication in a lymphoblastoid cell line by the α1-antitrypsin Portland variant (α1-PDX) and the decRVKRcmk peptide: comparison with HIV-1LAI

Bouchaib Bahbouhi, Mourad Bendjennat, Cristina Chiva, Marcelo Kogan, Fernando Albericio, Ernest Giralt, Nabil Georges Seidah, Elmostafa Bahraoui

Journal:

Microbes and Infection

Year:

2001

Language:

english

File:

PDF, 422 KB

english, 2001

30

Large Dense-Core Vesicles in Rat Adrenal After Reserpine: Levels of mRNAs of Soluble and Membrane-Bound: Constituents in Chromaffin and Ganglion Cells Indicate a Biosynthesis of Vesicles with Higher Secretory Quanta

Andrea Laslop, Sushil K. Mahata, Martin Wolkersdorfer, Manjula Mahata, Meera Srivastava, Nabil G. Seidah, Reiner Fischer-Colbrie, Hans Winkler

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1.80 MB

english, 1994

31

7B2 Is a Specific Intracellular Binding Protein of the Prohormone Convertase PC2

Suzanne Benjannet, Diane Savaria, Michel Chrétien, Nabil G. Seidah

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.12 MB

english, 1995

32

Proteolytic Processing of Chromogranin B and Secretogranin II by Prohormone Convertases

Andrea Laslop, Christian Weiss, Diane Savaria, Christine Eiter, Sharon A. Tooze, Nabil G. Seidah, Hans Winkler

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.01 MB

english, 1998

33

Coordinated Expression of β-Amyloid Precursor Protein and the Putative β-Secretase BACE and α-Secretase ADAM10 in Mouse and Human Brain

Mieczyslaw Marcinkiewicz, Nabil G. Seidah

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 548 KB

english, 2000

34

Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10

Elvira Lopez-Perez, Yue Zhang, Stuart J Frank, John Creemers, Nabil Seidah, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 457 KB

english, 2001

35

Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study

Pierre Villeneuve, Sylvain Feliciangeli, Gilles Croissandeau, Nabil G. Seidah, Majambu Mbikay, Patrick Kitabgi, Alain Beaudet

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 593 KB

english, 2002

36

Pro-opiomelanocortin-Related Peptides, Prohormone Convertases 1 and 2 and the Regulatory Peptide 7B2 are Present in Melanosomes of Human Melanocytes

Peters, Eva M J, Tobin, Desmond J, Seidah, Nabil G, Schallreuter, Karin U

Journal:

The Journal of Investigative Dermatology

Year:

2000

Language:

english

File:

PDF, 1.02 MB

english, 2000

37

Application of the multiple antigenic peptides (MAP) strategy to the production of prophormone convertases antibodies: Synthesis, characterization and use of 8-branched immunogenic peptides

Dr Ajoy Basak, Alain Boudreault, Andrew Chen, Michel Chrétien, Nabil G. Seidah, Claude Lazure

Journal:

Journal of Peptide Science

Year:

1995

Language:

english

File:

PDF, 1008 KB

english, 1995

38

Light and electron microscopic localization of the N-terminal fragment of human pro-opiomelanocortin in the human pituitary gland and in neoplasms

R. Yoshiyuki Osamura, Keiichi Watanabe, Nabil G. Seidah, John S. D. Chan, Michel Chrétien

Journal:

Virchows Archiv

Year:

1985

Language:

english

File:

PDF, 582 KB

english, 1985

39

The proprotein convertases are potential targets in the treatment of dyslipidemia

Nabil G. Seidah, Annik Prat

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 614 KB

english, 2007

40

Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy

Chiara Marchesi, Rachid Essalmani, Catherine A. Lemarié, Eyal Leibovitz, Talin Ebrahimian, Pierre Paradis, Nabil G. Seidah, Ernesto L. Schiffrin, Annik Prat

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 483 KB

english, 2011

41

Immunohistochemical localization of subtilisin/kexin-like proprotein convertases in human atherosclerosis

Philipp Stawowy, Heike Kallisch, Núbia Borges Pereira Stawowy, Dietger Stibenz, John P. Veinot, Michael Gräfe, Nabil G. Seidah, Michel Chrétien, Eckart Fleck, Kristof Graf

Journal:

Virchows Archiv

Year:

2005

Language:

english

File:

PDF, 850 KB

english, 2005

42

The Influence ofPCSK9Polymorphisms on Serum Low-Density Lipoprotein Cholesterol and Risk of Atherosclerosis

Jean Davignon, Geneviève Dubuc, Nabil G. Seidah

Journal:

Current Atherosclerosis Reports

Year:

2010

Language:

english

File:

PDF, 227 KB

english, 2010

43

The H5N1 Influenza Variant Fujian-Like Hemagglutinin Selected Following Vaccination Exhibits a Compromised Furin Cleavage

Antonella Pasquato, Nabil G. Seidah

Journal:

Journal of Molecular Neuroscience

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

44

Affinity purification of proteinases by a combination of immobilized peptidyl aldehyde and semicarbazone

Ajoy Basak, Xue Wen Yuan, Nabil G. Seidah, Michel Chrétien, Claude Lazure

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1992

Language:

english

File:

PDF, 1012 KB

english, 1992

45

Histidine-rich human salivary peptides are inhibitors of proprotein convertases furin and PC7 but act as substrates for PC1

AJOY BASAK, BLAIR ERNST, DYANNE BREWER, NABIL G. SEIDAH, JON S. MUNZER, CLAUDE LAZURE, GILLES A. LAJOIE

Journal:

Chemical Biology & Drug Design

Year:

1997

Language:

english

File:

PDF, 757 KB

english, 1997

46

β-Amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin

Louise Wickham, Suzanne Benjannet, Edwige Marcinkiewicz, Michel Chretien, Nabil G. Seidah

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 386 KB

english, 2005

47

Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system

Steve Poirier, Annik Prat, Edwige Marcinkiewicz, Joanne Paquin, Babykumari P. Chitramuthu, David Baranowski, Benoit Cadieux, Hugh P. J. Bennett, Nabil G. Seidah

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 441 KB

english, 2006

48

The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR

Nasha Nassoury, Daniel A. Blasiole, Angie Tebon Oler, Suzanne Benjannet, Josée Hamelin, Vivianne Poupon, Peter S. McPherson, Alan D. Attie, Annik Prat, Nabil G. Seidah

Journal:

Year:

2007

Language:

english

File:

PDF, 1.50 MB

english, 2007

49

The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR

Nasha Nassoury, Daniel A. Blasiole, Angie Tebon Oler, Suzanne Benjannet, Josée Hamelin, Vivianne Poupon, Peter S. McPherson, Alan D. Attie, Annik Prat, Nabil G. Seidah

Journal:

Year:

2007

Language:

english

File:

PDF, 26 KB

english, 2007

50

PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism

Jimmy D. Dikeakos, Chantal Mercure, Marie-Josée Lacombe, Nabil G. Seidah, Timothy L. Reudelhuber

Journal:

Year:

2007

Language:

english

File:

PDF, 705 KB

english, 2007