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51

Allelic variation in transcription modulates MHC class II expression and function

Jon S Beaty, Teresa L Sukiennicki, Gerald T Nepom

Journal:

Microbes and Infection

Year:

1999

Language:

english

File:

PDF, 282 KB

english, 1999

52

Amino Acids in the Peptide-Binding Groove Influence an Antibody-Defined, Disease-Associated HLA-DR Epitope

S. DROVER, W. H. MARSHALL, W. W. KWOK, G. T. NEPOM, R. W. KARR

Journal:

Scandinavian Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 4.87 MB

english, 1994

53

MHC-DRB allelic sequences incorporate distinct intragenic trans-specific segments

L. K. Gaur, G. T. Nepom, K. E. Snyder, J. Anderson, M. Pandarpurkar, W. Yadock, E. R. Heise

Journal:

Tissue Antigens

Year:

1997

Language:

english

File:

PDF, 4.11 MB

english, 1997

54

A real-time polymerase chain reaction assay for the rapid identification of the autoimmune disease-associated allele HLA-DQB1*0602

V. H. Gersuk, G. T. Nepom

Journal:

Tissue Antigens

Year:

2009

Language:

english

File:

PDF, 168 KB

english, 2009

55

Challenges in the pursuit of immune tolerance

Gerald T. Nepom, E. William St. Clair, Laurence A. Turka

Journal:

Immunological Reviews

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

56

Induction of Islet Allotolerance in Nonhuman Primates

LAKSHMI K. GAUR, Y. NITTA, E. KENNEDY, Å. LERNMARK, K. A. NELSON, M. ALLEN, G. T. NEPOM

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 1.39 MB

english, 2002

57

Immunization to a syngeneic sarcoma by a monoclonal auto-anti-idiotypic antibody

Forstrom, J. W., Nelson, K. A., Nepom, G. T., Hellström, I., Hellström, K. E.

Journal:

Year:

1983

File:

PDF, 392 KB

1983

58

HLA-DR antigens on lymphoid cells differ from those on myeloid cells

Torok-Storb, Beverly, Nepom, Gerald T., Nepom, Barbara S., Hansen, John A.

Journal:

Year:

1983

File:

PDF, 352 KB

1983

59

Animal models of human type 1 diabetes

von Herrath, Matthias, Nepom, Gerald T

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 180 KB

english, 2009

60

Class II peptide multimers: promise for type 1A diabetes?

Eisenbarth, George S., Nepom, Gerald T.

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 42 KB

english, 2002

61

Mucosal matters

Nepom, Gerald T.

Journal:

Nature Reviews Immunology

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

62

The Immune Tolerance Network at 10 years: tolerance research at the bedside

Bluestone, Jeffrey A., Auchincloss, Hugh, Nepom, Gerald T., Rotrosen, Daniel, St. Clair, E. William, Turka, Laurence A.

Journal:

Nature Reviews Immunology

Year:

2010

Language:

english

File:

PDF, 323 KB

english, 2010

63

HLA Heterozygosity in Insulin-Dependent Diabetes is Most Frequent at the DQ Locus

B. MICHELSEN, R. WASSMUTH, J. LUDVIGSSON, Å. LERNMARK, G. T. NEPOM, L. FISHER

Journal:

Scandinavian Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 664 KB

english, 1990

64

Induction of Donor-Specific Tolerance to Islet Allografts in Nonhuman Primates

LAKSHMI K. GAUR, E. KENNEDY, Y. NITTA, G. T. NEPOM, K. A. NELSON, M. ALLEN, Å. LERNMARK

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 1.36 MB

english, 2002

65

Detection of CD4+ Autoreactive T Cells in T1D Using HLA Class II Tetramers

HELENA REIJONEN, WILLIAM W. KWOK, GERALD T. NEPOM

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 2.25 MB

2003

66

Autoreactive T Cells in a Partially Humanized Murine Model of T1D

JOHN A. GEBE, BEN FALK, KELLEE UNRATH, GERALD T. NEPOM

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

67

MHC Class II Tetramers

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.47 MB

english, 2012

68

Differential Transcription Elements Direct Expression of HLA-DQ Genes

Ann E. Woolfrey, Gerald T. Nepom

Journal:

Clinical Immunology and Immunopathology

Year:

1995

File:

PDF, 658 KB

1995

69

Virus-binding receptors: Similarities to immune receptors as determined by anti-idiotypic antibodies

Jerry T. Nepom, Marc Tardieu, Rochelle L. Epstein, John H. Noseworthy, Howard L. Weiner, Jon Gentsch, Bernard N. Fields, Mark I. Greene

Journal:

Immunologic Research

Year:

1982

Language:

english

File:

PDF, 495 KB

english, 1982

70

Structural variation among major histocompatibility complex class-II genes which predispose to autoimmunity

Gerald T. Nepom

Journal:

Immunologic Research

Year:

1989

Language:

english

File:

PDF, 1.71 MB

english, 1989

71

Locus- and allele-specific DNA-protein interactions in the HLA-DQB1 X box

Teresa L. Sukiennicki, Linda M. Shewey, Gerald T. Nepom

Journal:

Immunologic Research

Year:

1993

Language:

english

File:

PDF, 1.25 MB

english, 1993

72

HLA class I and class II profiles of patients presenting with Sydenham’s chorea

Donadi, E. A., Voltarelli, J .C., Nepom, G. T., Smith, A. G., Louzada-Júnior, P.

Journal:

Journal of Neurology

Year:

2000

Language:

english

File:

PDF, 43 KB

english, 2000

73

Antibody responses to trinitrophenyl (TNP)-l-glutamic acid60-l-alanine30-l-tyrosine10 (GAT) in microcultures: Anti-hapten and anti-carrier responses appear to be under separable control

Norman L. Letvin, Kenneth L. Rock, Jerry T. Nepom, Colette F. Gramm, Baruj Benacerraf

Journal:

Cellular Immunology

Year:

1982

Language:

english

File:

PDF, 761 KB

english, 1982

74

Specific blocking factors — are they important?

Karl Erik Hellström, Ingegerd Hellström, Jerry T. Nepom

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1977

Language:

english

File:

PDF, 1.76 MB

english, 1977

75

Idiotypic interactions in immune responses to tumor-associated antigens

Victor K. Lee, Karl Erik Hellström, Gerald T. Nepom

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1986

Language:

english

File:

PDF, 1.03 MB

english, 1986

76

OR.45. Induction of Autoantigen-Specific Cd4+Cd25+ Regulatory T‐Cells In Vitro

Mindi Walker, Bryan Carson, Steven Ziegler, Gerald Nepom, Jane Buckner

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 48 KB

english, 2006

77

Su.36. Gad-Reactive, Effector Memory Cd4+ T-Cells Cultured from Type 1 Diabetic Patients Express Increased Levels of the Voltage-Gated Potassium Channel Kv1.3: a Potential Therapeutic Target

Nathan Standifer, Christine Beeton, K. George Chandy, Gerald Nepom

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 42 KB

english, 2006

78

Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice

John A. Gebe, Kellee A Unrath, Ben A. Falk, Kouichi Ito, Li Wen, Terri L. Daniels, Åke Lernmark, Gerald T. Nepom

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 1.92 MB

english, 2006

79

Protective Versus Aggressive T Cell Responses to the Major Proinsulin73–90 Epitope in Beta-Islet Cell Autoimmunity

Ivana Durinovic-Bello, Nicol Pratt, Susan A. Masewicz, Gerald Nepom

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 41 KB

english, 2007

80

Evidence for an Increase in the Functional Avidity of the GAD-reactive CD4+ T Cell Population Prior to Diabetes Onset

Nathan Standifer, Gerald Nepom

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 43 KB

english, 2007

81

High Molecular Weight Hyaluronan Promotes the Suppressive Effects of CD4+CD25+ T-reg

Paul Bollyky, Gerald Nepom, Jane Buckner, Susan Masewicz, James Lord, Stephen Evanko, Thomas Wight

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 38 KB

english, 2007

82

OR.9. A Shift in Autoreactive CD4 T Cell Avidity Preceding Diagnosis with Type 1 Diabetes is Correlated with the Outgrowth of Distinct T Cell Clonotypes

Nathan Standifer, Gerald Nepom

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 37 KB

english, 2008

83

OR.31. CD44 Cross-linking Potently Induces FoxP3 and Promotes CD4+CD25+ Regulatory T Cell Mediated Suppression

Paul Bollyky, Rebecca Wu, Ben Falk, Thomas Wight, Jane Buckner, Gerald Nepom

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 36 KB

english, 2008

84

A nexus of science and clinical immunology: The Federation of Clinical Immunology Societies and the FOCIS Centers of Excellence

Michael T. Lotze, Gerald T. Nepom

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 133 KB

english, 2008

85

Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation

Elsa Laughlin, George Burke, Alberto Pugliese, Ben Falk, Gerald Nepom

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 956 KB

english, 2008

86

Approaching the Heisenberg principle of immunology

Gerald T. Nepom

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 137 KB

english, 2008

87

Tissue Environment Modulates FoxP3+Regulatory T Cells (Treg) Through Interactions with Extracellular Matrix

Paul Bollyky, Ben Falk, S. Alice Long, Rebecca Wu, Stephen Evanko, Jane Buckner, Thomas Wight, Gerald Nepom

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

88

T.128. Short-term Administration of Anakinra does not Appear to Affect Stimulated C-peptide Responses Acutely in Patients with Type 1 Diabetes

Srinath Sanda, Jennifer Bollyky, Emily Burwell, Nathan Standifer, Gerald Nepom, Carla Greenbaum

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 36 KB

english, 2009

89

F.69. Selection of Antigen Specific Autoreactive T Cells is Influenced by INS-VNTR Genotype

Ivana Durinovic-Bello, Rebecca Wu, Srinath Sanda, Gerald Nepom

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

90

S.48. Longitudinal Dynamics of CD4+T Cell Responses to an Insulin Peptide in Healthy, Autoantibody-positive and Type 1 Diabetic Subjects

Nathan Standifer, Emily Burwell, Gerald Nepom

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

91

Changes in autoreactive T cell avidity during type 1 diabetes development

Nathan E. Standifer, Emily A. Burwell, Vivian H. Gersuk, Carla J. Greenbaum, Gerald T. Nepom

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 776 KB

english, 2009

92

Insulin Gene VNTR Genotype Associates with Frequency and Phenotype of the Autoimmune Response to Proinsulin

Ivana Durinovic-Belló, Vivian Gersuk, Rebecca Wu, Jessica Matthis, Gerald Nepom

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 75 KB

english, 2010

93

Autoantigen T Cell Immune Responses Observed in the DR0401/DR0404 MHC-generated T Cell Repertoire that are Absent in the Homozygous DR0401 or DR0404 Restricted T Cell Repertoire

John Gebe, Betty Yue, Mary Rieck, Anton Preisinger, Eddie James, Crystal Rawlings, Brad Stone, Jane Buckner, Gerald Nepom

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

94

Reduced CD11b Integrin Expression with Short-term Administration of an IL-1R Antagonist in Type 1 Diabetes Patients

Srinath Sanda, Jenna Bollyky, Gerald Nepom, Jessica Hamerman, Carla Greenbaum

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

95

Short-term IL-1β blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes

Srinath Sanda, Jenna Bollyky, Nathan Standifer, Gerald Nepom, Jessica A. Hamerman, Carla Greenbaum

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 488 KB

english, 2010

96

Ultra-sensitive detection of rare T cell clones

Harlan Robins, Cindy Desmarais, Jessica Matthis, Robert Livingston, Jessica Andriesen, Helena Reijonen, Christopher Carlson, Gerold Nepom, Cassian Yee, Karen Cerosaletti

Journal:

Journal of Immunological Methods

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012

97

T Cell Autoreactivity in the Transplant Milieu

J. Matthis, G. T. Nepom

Journal:

American Journal of Transplantation

Year:

2012

Language:

english

File:

PDF, 658 KB

english, 2012

98

HLA-DQ heterogeneity among HLA-DRw11(5) haplotypes

Avraham Amar, Eric Mickelson, John A. Hansen, Gerald T. Nepom

Journal:

Tissue Antigens

Year:

1986

Language:

english

File:

PDF, 624 KB

english, 1986

99

Allorecognition of HLA-DQw8 molecules: Influence of single amino acid substitutions

Henrik A. Gjersten, Knut E. A. Lundin, William W. Kwok, Gerald T. Nepom, Erik Thorsby

Journal:

Tissue Antigens

Year:

1992

Language:

english

File:

PDF, 332 KB

english, 1992

100

Analysis of HLA-DQA1 and -DQB1 genes in Mexican Americans with insulin-dependent diabetes mellitus

C. B. Sanjeevi, A. Zeidler, S. Shaw, J. Rotter, G. T. Nepom, G. Costin, L. Raffel, S. Eastman, I. Kockum, R. Wassmuth, Å. Lernmark

Journal:

Tissue Antigens

Year:

1993

Language:

english

File:

PDF, 517 KB

english, 1993

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